PMC Links for Gene (Select 20595) - PMC

Tejal Aslesh, Esra Erkut, Jun Ren, Kenji Rowel Q. Lim, Stanley Woo, Susan Hatlevig, Hong M. Moulton, Simon Gosgnach, John Greer, Rika Maruyama, Toshifumi Yokota

JCI Insight. 2023 Mar 8; 8(5): e160516. Published online 2023 Mar 8. doi: 10.1172/jci.insight.160516

PMCID:: PMC10077475

Abstract Article PDF–9.0M

Select item 99617524.

Long-Term SMN- and Ncald-ASO Combinatorial Therapy in SMA Mice and NCALD-ASO Treatment in hiPSC-Derived Motor Neurons Show Protective Effects

Anixa Muiños-Bühl, Roman Rombo, Karen K. Ling, Eleonora Zilio, Frank Rigo, C. Frank Bennett, Brunhilde Wirth

Int J Mol Sci. 2023 Feb; 24(4): 4198. Published online 2023 Feb 20. doi: 10.3390/ijms24044198

PMCID:: PMC9961752

Abstract Article PDF–7.9M

Select item 96211285.

Microvasculopathy in spinal muscular atrophy is driven by a reversible autonomous endothelial cell defect

Haiyan Zhou, Ying Hong, Mariacristina Scoto, Alison Thomson, Emma Pead, Tom MacGillivray, Elena Hernandez-Gerez, Francesco Catapano, Jinhong Meng, Qiang Zhang, Gillian Hunter, Hannah K. Shorrock, Thomas K. Ng, Abedallah Hamida, Mathilde Sanson, Giovanni Baranello, Kevin Howell, Thomas H. Gillingwater, Paul Brogan, Dorothy A. Thompson, Simon H. Parson, Francesco Muntoni

J Clin Invest. 2022 Nov 1; 132(21): e153430. Published online 2022 Nov 1. doi: 10.1172/JCI153430

PMCID:: PMC9621128

Abstract Article PDF–10M

Select item 88342386.

Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy

Markus Leo, Linda-Isabell Schmitt, Michael Fleischer, Rebecca Steffen, Cora Osswald, Christoph Kleinschnitz, Tim Hagenacker

Cells. 2022 Feb; 11(3): 558. Published online 2022 Feb 5. doi: 10.3390/cells11030558

PMCID:: PMC8834238

Abstract Article PDF–31M

Select item 84100727.

Combining multiomics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy

Katharina E. Meijboom, Viola Volpato, Jimena Monzón-Sandoval, Joseph M. Hoolachan, Suzan M. Hammond, Frank Abendroth, Olivier G. de Jong, Gareth Hazell, Nina Ahlskog, Matthew J.A. Wood, Caleb Webber, Melissa Bowerman

JCI Insight. 2021 Jul 8; 6(13): e149446. Published online 2021 Jul 8. doi: 10.1172/jci.insight.149446

PMCID:: PMC8410072

Abstract Article PDF–8.8M

Select item 82574588.

SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease

Marc-Olivier Deguise, Chantal Pileggi, Yves De Repentigny, Ariane Beauvais, Alexandra Tierney, Lucia Chehade, Jean Michaud, Maica Llavero-Hurtado, Douglas Lamont, Abdelmadjid Atrih, Thomas M. Wishart, Thomas H. Gillingwater, Bernard L. Schneider, Mary-Ellen Harper, Simon H. Parson, Rashmi Kothary

Cell Mol Gastroenterol Hepatol. 2021; 12(1): 354–377.e3. Published online 2021 Feb 2. doi: 10.1016/j.jcmgh.2021.01.019

PMCID:: PMC8257458

Abstract Article PDF–7.7M

Select item 81274089.

Calcium is reduced in presynaptic mitochondria of motor nerve terminals during neurotransmission in SMA mice

Mario Lopez-Manzaneda, Julio Franco-Espin, Rocio Tejero, Raquel Cano, Lucia Tabares

Hum Mol Genet. 2021 Apr 15; 30(8): 629–643. Published online 2021 Mar 9. doi: 10.1093/hmg/ddab065

PMCID:: PMC8127408

Abstract Article PDF–3.7M

Select item 718416110.

Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy

Marc-Olivier Deguise, Yves De Repentigny, Alexandra Tierney, Ariane Beauvais, Jean Michaud, Lucia Chehade, Mohamed Thabet, Brittany Paul, Aoife Reilly, Sabrina Gagnon, Jean-Marc Renaud, Rashmi Kothary

EBioMedicine. 2020 May; 55: 102750. Published online 2020 Apr 24. doi: 10.1016/j.ebiom.2020.102750

Correction in:: EBioMedicine. 2021 Apr; 66: 103295.

PMCID:: PMC7184161

Abstract Article PDF–4.0M

Select item 710299411.

Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model

Lei Sheng, Frank Rigo, C Frank Bennett, Adrian R Krainer, Yimin Hua

Nucleic Acids Res. 2020 Apr 6; 48(6): 2853–2865. Published online 2020 Feb 27. doi: 10.1093/nar/gkaa126

PMCID:: PMC7102994

Abstract Article PDF–8.2M

Select item 684309512.

Hyperexcitability precedes motoneuron loss in the Smn^2B/− mouse model of spinal muscular atrophy

K. A. Quinlan, E. J. Reedich, W. D. Arnold, A. C. Puritz, C. F. Cavarsan, C. J. Heckman, C. J. DiDonato

J Neurophysiol. 2019 Oct 1; 122(4): 1297–1311. Published online 2019 Jul 31. doi: 10.1152/jn.00652.2018

PMCID:: PMC6843095

Abstract Article

Select item 678161313.

Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy

Léo Houdebine, Domenico D’Amico, Jean Bastin, Farah Chali, Céline Desseille, Valentin Rumeau, Judy Soukkari, Carole Oudot, Thaïs Rouquet, Bruno Bariohay, Julien Roux, Delphine Sapaly, Laure Weill, Philippe Lopes, Fatima Djouadi, Cynthia Bezier, Frédéric Charbonnier, Olivier Biondi

Front Physiol. 2019; 10: 1258. Published online 2019 Oct 1. doi: 10.3389/fphys.2019.01258

PMCID:: PMC6781613

Abstract Article PDF–6.8M

Select item 672540514.

Regular Exercise Prolongs Survival in a Type 2 Spinal Muscular Atrophy Model Mouse

Clément Grondard, Olivier Biondi, Anne-Sophie Armand, Sylvie Lécolle, Bruno Della Gaspera, Claude Pariset, Hung Li, Claude-Louis Gallien, Pierre-Paul Vidal, Christophe Chanoine, Frédéric Charbonnier

J Neurosci. 2005 Aug 17; 25(33): 7615–7622. doi: 10.1523/JNEUROSCI.1245-05.2005

Correction in:: J Neurosci. 2005 Sep 14; 25(37): 8587.

PMCID:: PMC6725405

Abstract Article PDF–382K

Select item 661252015.

NCALD Antisense Oligonucleotide Therapy in Addition to Nusinersen further Ameliorates Spinal Muscular Atrophy in Mice

Laura Torres-Benito, Svenja Schneider, Roman Rombo, Karen K. Ling, Vanessa Grysko, Aaradhita Upadhyay, Natalia L. Kononenko, Frank Rigo, C. Frank Bennett, Brunhilde Wirth

Am J Hum Genet. 2019 Jul 3; 105(1): 221–230. Published online 2019 Jun 20. doi: 10.1016/j.ajhg.2019.05.008

PMCID:: PMC6612520

Abstract Article PDF–1.6M

Select item 652787716.

Survival Motor Neuron (SMN) Protein Insufficiency Exacerbates Renal Ischemia/Reperfusion Injury

Xiaoqian Qian, Yichao Du, Gengru Jiang, Fujun Lin, Lei Yao

Front Physiol. 2019; 10: 559. Published online 2019 May 14. doi: 10.3389/fphys.2019.00559

PMCID:: PMC6527877

Abstract Article PDF–2.8M

Select item 648218717.

SMN deficiency causes pain hypersensitivity in a mild SMA mouse model through enhancing excitability of nociceptive dorsal root ganglion neurons

Ruobing Qu, Fuping Yao, Xiaomin Zhang, Yuan Gao, Tong Liu, Yimin Hua

Sci Rep. 2019; 9: 6493. Published online 2019 Apr 24. doi: 10.1038/s41598-019-43053-5

PMCID:: PMC6482187

Abstract Article PDF–2.2M

Select item 596384218.

Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology

Luke W. Thompson, Kim D. Morrison, Sally L. Shirran, Ewout J. N. Groen, Thomas H. Gillingwater, Catherine H. Botting, Judith E. Sleeman

J Cell Sci. 2018 Apr 15; 131(8): jcs211482. Published online 2018 Apr 17. doi: 10.1242/jcs.211482

PMCID:: PMC5963842

Abstract Article

Select item 588617219.

Downregulation of Survivin contributes to cell-cycle arrest during postnatal cardiac development in a severe spinal muscular atrophy mouse model

Lei Sheng, Bo Wan, Pengchao Feng, Junjie Sun, Frank Rigo, C Frank Bennett, Martin Akerman, Adrian R Krainer, Yimin Hua

Hum Mol Genet. 2018 Feb 1; 27(3): 486–498. Published online 2017 Dec 6. doi: 10.1093/hmg/ddx418

PMCID:: PMC5886172

Abstract Article PDF–1.5M

Select item 579498620.

Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy

Delphine Sapaly, Matthieu Dos Santos, Perrine Delers, Olivier Biondi, Gwendoline Quérol, Léo Houdebine, Kevinee Khoobarry, François Girardet, Philippe Burlet, Anne-Sophie Armand, Christophe Chanoine, Jean-François Bureau, Frédéric Charbonnier, Suzie Lefebvre

Sci Rep. 2018; 8: 2075. Published online 2018 Feb 1. doi: 10.1038/s41598-018-20219-1

PMCID:: PMC5794986

Abstract Article PDF–6.3M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 282

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity