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Select item 108003571.

Macrophage SREBP1 regulates skeletal muscle regeneration

Yumiko Oishi, Hiroyuki Koike, Naoki Kumagami, Yoshimi Nakagawa, Masaya Araki, Yoshitaka Taketomi, Yoshimi Miki, Shigeru Matsuda, Hyeree Kim, Takashi Matsuzaka, Hitoshi Ozawa, Hitoshi Shimano, Makoto Murakami, Ichiro Manabe

Front Immunol. 2023; 14: 1251784. Published online 2024 Jan 8. doi: 10.3389/fimmu.2023.1251784

Correction in:: Front Immunol. 2024; 15: 1382077.

PMCID:: PMC10800357

Abstract Article PDF–7.7M

Select item 90398362.

Srebf1c preserves hematopoietic stem cell function and survival as a switch of mitochondrial metabolism

Yukai Lu, Zihao Zhang, Song Wang, Yan Qi, Fang Chen, Yang Xu, Mingqiang Shen, Mo Chen, Naicheng Chen, Lijing Yang, Shilei Chen, Fengchao Wang, Yongping Su, Mengjia Hu, Junping Wang

Stem Cell Reports. 2022 Mar 8; 17(3): 599–615. Published online 2022 Feb 10. doi: 10.1016/j.stemcr.2022.01.011

PMCID:: PMC9039836

Abstract Article PDF–6.1M

Select item 87267043.

Impairment of ULK1 sulfhydration-mediated lipophagy by SREBF1/SREBP-1c in hepatic steatosis

Thuy T.P. Nguyen, Do-Young Kim, Seung-Soon Im, Tae-Il Jeon

Autophagy. 2021; 17(12): 4489–4490. Published online 2021 Aug 30. doi: 10.1080/15548627.2021.1968608

PMCID:: PMC8726704

Abstract Article PDF–428K

Select item 82011434.

SREBP-1c Deficiency Affects Hippocampal Micromorphometry and Hippocampus-Dependent Memory Ability in Mice

Mary Jasmin Ang, Sueun Lee, Mai Wada, Poornima D. E. Weerasinghe-Mudiyanselage, Sung-Ho Kim, Taekyun Shin, Tae-Il Jeon, Seung-Soon Im, Changjong Moon

Int J Mol Sci. 2021 Jun; 22(11): 6103. Published online 2021 Jun 5. doi: 10.3390/ijms22116103

PMCID:: PMC8201143

Abstract Article PDF–2.0M

Select item 75203385.

Mechanistic insights into the effects of SREBP1c on hepatic stellate cell and liver fibrosis

Shengyan Su, Haimeng Tian, Xin Jia, Xiaofei Zhu, Juanjuan Wu, Yali Zhang, Yuanyuan Chen, Ziqiang Li, Yajun Zhou

J Cell Mol Med. 2020 Sep; 24(17): 10063–10074. Published online 2020 Jul 17. doi: 10.1111/jcmm.15614

PMCID:: PMC7520338

Abstract Article PDF–2.4M

Select item 59795616.

Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes

Birgit Knebel, Sonja Hartwig, Sylvia Jacob, Ulrike Kettel, Martina Schiller, Waltraud Passlack, Cornelia Koellmer, Stefan Lehr, Dirk Müller-Wieland, Jorg Kotzka

Int J Mol Sci. 2018 Apr; 19(4): 980. Published online 2018 Mar 25. doi: 10.3390/ijms19040980

PMCID:: PMC5979561

Abstract Article PDF–4.9M

Select item 59337927.

Impact of silencing hepatic SREBP-1 on insulin signaling

Victoria Jideonwo, Yongyong Hou, Miwon Ahn, Sneha Surendran, Núria Morral

PLoS One. 2018; 13(5): e0196704. Published online 2018 May 3. doi: 10.1371/journal.pone.0196704

PMCID:: PMC5933792

Abstract Article PDF–3.4M

Select item 56604628.

RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer

Jae Ho Lee, Yong Geun Jeon, Kyoung-Hwa Lee, Hye Won Lee, Jeu Park, Hagoon Jang, Minyong Kang, Hye Sun Lee, Hee Jin Cho, Do-Hyun Nam, Cheol Kwak, Jae Bum Kim

Mol Cell Biol. 2017 Nov 15; 37(22): e00265-17. Prepublished online 2017 Aug 21. Published online 2017 Oct 27. doi: 10.1128/MCB.00265-17

PMCID:: PMC5660462

Abstract Article PDF–5.1M

Select item 54181919.

Sterol regulatory element‐binding protein‐1c orchestrates metabolic remodeling of white adipose tissue by caloric restriction

Namiki Fujii, Takumi Narita, Naoyuki Okita, Masaki Kobayashi, Yurika Furuta, Yoshikazu Chujo, Masahiro Sakai, Atsushi Yamada, Kanae Takeda, Tomokazu Konishi, Yuka Sudo, Isao Shimokawa, Yoshikazu Higami

Aging Cell. 2017 Jun; 16(3): 508–517. Published online 2017 Mar 3. doi: 10.1111/acel.12576

PMCID:: PMC5418191

Abstract Article PDF–728K

Select item 462514410.

Dietary fiber prevents obesity-related liver lipotoxicity by modulating sterol-regulatory element binding protein pathway in C57BL/6J mice fed a high-fat/cholesterol diet

Shufen Han, Jun Jiao, Wei Zhang, Jiaying Xu, Zhongxiao Wan, Weiguo Zhang, Xiaoran Gao, Liqiang Qin

Sci Rep. 2015; 5: 15256. Published online 2015 Oct 29. doi: 10.1038/srep15256

PMCID:: PMC4625144

Abstract Article PDF–943K

Select item 382667511.

Adaptive responses by mouse fetus to a maternal HLE diet by downregulating SREBP1: a microarray- and bio-analytic-based study

Huan-Ling Yu, Huang-Tai Miao, Li-Fang Gao, Li Li, Yuan-Di Xi, Shao-Ping Nie, Rong Xiao

J Lipid Res. 2013 Dec; 54(12): 3269–3280. doi: 10.1194/jlr.M037416

PMCID:: PMC3826675

Abstract Article PDF–2.2M

Select item 309063012.

Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein -1a

Seung-Soon Im, Leyla Yousef, Christoph Blaschitz, Janet Z. Liu, Robert A. Edwards, Stephen G. Young, Manuela Raffatellu, Timothy F. Osborne

Cell Metab. Author manuscript; available in PMC 2012 May 4.

Published in final edited form as: Cell Metab. 2011 May 4; 13(5): 540–549. doi: 10.1016/j.cmet.2011.04.001

PMCID:: PMC3090630

Abstract Article PDF–1.7M

Select item 296340513.

Time of Day and Nutrients in Feeding Govern Daily Expression Rhythms of the Gene for Sterol Regulatory Element-binding Protein (SREBP)-1 in the Mouse Liver

Eriko Matsumoto, Akinori Ishihara, Saki Tamai, Ayako Nemoto, Katsuro Iwase, Takaki Hiwasa, Shigenobu Shibata, Masaki Takiguchi

J Biol Chem. 2010 Oct 22; 285(43): 33028–33036. Published online 2010 Aug 18. doi: 10.1074/jbc.M109.089391

PMCID:: PMC2963405

Abstract Article PDF–2.3M

Select item 286790214.

A feed-forward loop amplifies nutritional regulation of PNPLA3

Yongcheng Huang, Shaoqing He, John Zhong Li, Young-Kyo Seo, Timothy F. Osborne, Jonathan C. Cohen, Helen H. Hobbs

Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17): 7892–7897. Published online 2010 Apr 12. doi: 10.1073/pnas.1003585107

PMCID:: PMC2867902

Abstract Article PDF–835K

Select item 278519115.

Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice

Hervé Lerat, Hélène L. Kammoun, Isabelle Hainault, Emilie Mérour, Martin R. Higgs, Céline Callens, Stanley M. Lemon, Fabienne Foufelle, Jean-Michel Pawlotsky

J Biol Chem. 2009 Nov 27; 284(48): 33466–33474. Published online 2009 Oct 6. doi: 10.1074/jbc.M109.019810

PMCID:: PMC2785191

Abstract Article PDF–1.2M

Select item 272896816.

Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif

Young-Kyo Seo, Hansook Kim Chong, Aniello M. Infante, Seung-Soon Im, Xiaohui Xie, Timothy F. Osborne

Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33): 13765–13769. Published online 2009 Aug 4. doi: 10.1073/pnas.0904246106

PMCID:: PMC2728968

Abstract Article PDF–948K

Select item 50789117.

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

H Shimano, J D Horton, I Shimomura, R E Hammer, M S Brown, J L Goldstein

J Clin Invest. 1997 Mar 1; 99(5): 846–854. doi: 10.1172/JCI119248

PMCID:: PMC507891

Summary PDF–411K

Select item 3394218.

ADD-1 provides major new insight into the mechanism of insulin action

Jeffrey S. Flier, Anthony N. Hollenberg

Proc Natl Acad Sci U S A. 1999 Dec 7; 96(25): 14191–14192. doi: 10.1073/pnas.96.25.14191

PMCID:: PMC33942

Article PDF–55K

Select item 1105887619.

Loss of SREBP-1c ameliorates iron-induced liver fibrosis by decreasing lipocalin-2

Eun-Ho Lee, Jae-Ho Lee, Do-Young Kim, Young-Seung Lee, Yunju Jo, Tam Dao, Kyung Eun Kim, Dae-Kyu Song, Ji Hae Seo, Young-Kyo Seo, Je Kyung Seong, Changjong Moon, Eugene Han, Mi Kyung Kim, Seungwan Ryu, Minsang Shin, Gu Seob Roh, Hye Ra Jung, Timothy F. Osborne, Dongryeol Ryu, Tae-Il Jeon, Seung-Soon Im

Exp Mol Med. 2024 Apr; 56(4): 1001–1012. Published online 2024 Apr 16. doi: 10.1038/s12276-024-01213-2