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Items: 1 to 20 of 26

1.
The Rho-guanine nucleotide exchange factor PDZ-RhoGEF governs susceptibility to diet-induced obesity and type 2 diabetes
Ying-Ju Chang, Scott Pownall, Thomas E Jensen, Samar Mouaaz, Warren Foltz, Lily Zhou, Nicole Liadis, Minna Woo, Zhenyue Hao, Previn Dutt, Philip J Bilan, Amira Klip, Tak Mak, Vuk Stambolic
eLife. 2015; 4: e06011. Published online 2015 Oct 29. doi: 10.7554/eLife.06011
PMCID:
PMC4709268
AbstractArticlePDF–3.9M
2.
Arhgef1 Plays a Vital Role in Platelet Function and Thrombogenesis
Hanan Qasim, Zubair A. Karim, Keziah R. Hernandez, Dante Lozano, Fadi T. Khasawneh, Fatima Z. Alshbool
J Am Heart Assoc. 2019 May 7; 8(9): e011712. Published online 2019 Apr 17. doi: 10.1161/JAHA.118.011712
PMCID:
PMC6512111
AbstractArticlePDF–2.1M
3.
Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-Myosin II signaling
Masahiko Itoh, Sachiko Tsukita, Yuji Yamazaki, Hiroyuki Sugimoto
Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25): 9905–9910. Published online 2012 Jun 4. doi: 10.1073/pnas.1115063109
PMCID:
PMC3382488
AbstractArticlePDF–1.9M
4.
Rho GEF Lsc is required for normal polarization, migration, and adhesion of formyl-peptide–stimulated neutrophils
Sanjeev A. Francis, Xun Shen, Jeffrey B. Young, Prashant Kaul, Daniel J. Lerner
Blood. 2006 Feb 15; 107(4): 1627–1635. Prepublished online 2005 Nov 1. doi: 10.1182/blood-2005-03-1164
PMCID:
PMC1895409
AbstractArticle
5.
Formation and contraction of multicellular actomyosin cables facilitate lens placode invagination
Nathalie S. Houssin, Jessica B. Martin, Vincenzo Coppola, Sung Ok Yoon, Timothy F. Plageman, Jr.
Dev Biol. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Dev Biol. 2020 Jun 1; 462(1): 36–49. Published online 2020 Feb 28. doi: 10.1016/j.ydbio.2020.02.014
PMCID:
PMC7225080
AbstractArticlePDF–4.3M
6.
Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
SungKyoung Lee, Benjamin Cieply, Yueqin Yang, Natoya Peart, Carl Glaser, Patricia Chan, Russ P. Carstens
Cell Rep. Author manuscript; available in PMC 2019 Feb 12.
Published in final edited form as: Cell Rep. 2018 Nov 27; 25(9): 2417–2430.e5. doi: 10.1016/j.celrep.2018.10.097
PMCID:
PMC6371790
AbstractArticlePDF–2.3M
7.
PDZ-RhoGEF and LARG Are Essential for Embryonic Development and Provide a Link between Thrombin and LPA Receptors and Rho Activation
Constantinos M. Mikelis, Todd R. Palmby, May Simaan, Wenling Li, Roman Szabo, Ruth Lyons, Daniel Martin, Hiroshi Yagi, Shigetomo Fukuhara, Hiroki Chikumi, Rebeca Galisteo, Yoh-suke Mukouyama, Thomas H. Bugge, J. Silvio Gutkind
J Biol Chem. 2013 Apr 26; 288(17): 12232–12243. Published online 2013 Mar 6. doi: 10.1074/jbc.M112.428599
PMCID:
PMC3636907
AbstractArticlePDF–3.7M
8.
Agonist-induced Ca2+ Sensitization in Smooth Muscle: REDUNDANCY OF RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS (RhoGEFs) AND RESPONSE KINETICS, A CAGED COMPOUND STUDY
Mykhaylo V. Artamonov, Ko Momotani, Andra Stevenson, David R. Trentham, Urszula Derewenda, Zygmunt S. Derewenda, Paul W. Read, J. Silvio Gutkind, Avril V. Somlyo
J Biol Chem. 2013 Nov 22; 288(47): 34030–34040. Published online 2013 Oct 8. doi: 10.1074/jbc.M113.514596
PMCID:
PMC3837142
AbstractArticlePDF–1.8M
9.
ESRP1 mutations cause hearing loss due to defects in alternative splicing that disrupt cochlear development
Alex M. Rohacek, Thomas W. Bebee, Richard K. Tilton, Caleb M. Radens, Chris McDermott-Roe, Natoya Peart, Maninder Kaur, Michael Zaykaner, Benjamin Cieply, Kiran Musunuru, Yoseph Barash, John A. Germiller, Ian D. Krantz, Russ P. Carstens, Douglas J. Epstein
Dev Cell. Author manuscript; available in PMC 2018 Nov 6.
Published in final edited form as: Dev Cell. 2017 Nov 6; 43(3): 318–331.e5. Published online 2017 Oct 26. doi: 10.1016/j.devcel.2017.09.026
PMCID:
PMC5687886
AbstractArticlePDF–2.4M
10.
Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk
SungKyoung Lee, Matthew J. Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun-Duck Nah, Trevor Williams, Russ P. Carstens
Development. 2020 Nov 1; 147(21): dev187369. Published online 2020 May 4. doi: 10.1242/dev.187369
PMCID:
PMC7225129
AbstractArticle
11.
The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development
Thomas W Bebee, Juw Won Park, Katherine I Sheridan, Claude C Warzecha, Benjamin W Cieply, Alex M Rohacek, Yi Xing, Russ P Carstens
eLife. 2015; 4: e08954. Published online 2015 Sep 15. doi: 10.7554/eLife.08954
PMCID:
PMC4566030
AbstractArticlePDF–3.9M
12.
Interactome Mapping of the Phosphatidylinositol 3-Kinase-Mammalian Target of Rapamycin Pathway Identifies Deformed Epidermal Autoregulatory Factor-1 as a New Glycogen Synthase Kinase-3 Interactor
Fanny Pilot-Storck, Emilie Chopin, Jean-François Rual, Anais Baudot, Pavel Dobrokhotov, Marc Robinson-Rechavi, Christine Brun, Michael E. Cusick, David E. Hill, Laurent Schaeffer, Marc Vidal, Evelyne Goillot
Mol Cell Proteomics. 2010 Jul; 9(7): 1578–1593. Published online 2010 Apr 5. doi: 10.1074/mcp.M900568-MCP200
PMCID:
PMC2938100
AbstractArticlePDF–1.1M
13.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
14.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
15.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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