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Select item 108914631.

Are embryonic stem cell markers and ALDH1A1 relevant in the context of breast cancer estrogen positivity?

Noha A. Mousa, Amal Hussein, Noha M. Elemam, Ghada Mohammed, Mona Elwany, Tasneem Basha, Amal A. AlHammadi, Rana S. Majzob, Iman M. Talaat

Cancer Med. 2024 Feb; 13(3): e7004. Published online 2024 Feb 24. doi: 10.1002/cam4.7004

Correction in:: Cancer Med. 2024 Apr; 13(8): e7171.

PMCID:: PMC10891463

Abstract Article PDF–27M

Select item 107580612.

ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription

Ielizaveta Gorodetska, Anne Offermann, Jakob Püschel, Vasyl Lukiyanchuk, Diana Gaete, Anastasia Kurzyukova, Vera Freytag, Marie-Therese Haider, Christina S Fjeldbo, Simona Di Gaetano, Franziska Maria Schwarz, Shivaprasad Patil, Angelika Borkowetz, Holger H. H. Erb, Aria Baniahmad, Jovan Mircetic, Heidi Lyng, Steffen Löck, Annett Linge, Tobias Lange, Franziska Knopf, Ben Wielockx, Mechthild Krause, Sven Perner, Anna Dubrovska

Theranostics. 2024; 14(2): 714–737. Published online 2024 Jan 1. doi: 10.7150/thno.88057

PMCID:: PMC10758061

Abstract Article PDF–14M

Select item 102538563.

The Molecular Context of Oxidant Stress Response in Cancer Establishes ALDH1A1 as a Critical Target: What This Means for Acute Myeloid Leukemia

Garrett M. Dancik, Lokman Varisli, Spiros A. Vlahopoulos

Int J Mol Sci. 2023 Jun; 24(11): 9372. Published online 2023 May 27. doi: 10.3390/ijms24119372

PMCID:: PMC10253856

Abstract Article PDF–864K

Select item 98918524.

Proteomic profiling reveals an association between ALDH and oxidative phosphorylation and DNA damage repair pathways in human colon adenocarcinoma stem cells

Yewei Wang, Ying Chen, Rolando Garcia-Milian, Jaya Prakash Golla, Georgia Charkoftaki, TuKiet T Lam, David C. Thompson, Vasilis Vasiliou

Chem Biol Interact. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Chem Biol Interact. 2022 Dec 1; 368: 110175. Published online 2022 Sep 23. doi: 10.1016/j.cbi.2022.110175

PMCID:: PMC9891852

Abstract Article PDF–1.1M

Select item 97774395.

ALDH1-Mediated Autophagy Sensitizes Glioblastoma Cells to Ferroptosis

Yang Wu, Helena Kram, Jens Gempt, Friederike Liesche-Starnecker, Wei Wu, Jürgen Schlegel

Cells. 2022 Dec; 11(24): 4015. Published online 2022 Dec 12. doi: 10.3390/cells11244015

PMCID:: PMC9777439

Abstract Article PDF–2.3M

Select item 92726106.

Association of ALDH1 with Response to Radiotherapy and Its Impact on Survival in Patients with Advanced Stage of Head and Neck Squamous Cell Carcinoma (HNSCC)

Parul Dubey, Narayan Kumar, Rajeev Gupta, Anupam Mishra, Smrati Bhadauria, Vijay Kumar, Madanlal Brahma Bhatt

Asian Pac J Cancer Prev. 2022 Feb; 23(2): 419–427. doi: 10.31557/APJCP.2022.23.2.419

PMCID:: PMC9272610

Abstract Article PDF–1006K

Select item 91093837.

An antisense Alu transposon insertion/deletion polymorphism of ALDH1A1 may functionally associate with Parkinson’s disease

Hui-Hui Fan, Jing Zheng, Xiao-Ya Huang, Ke-Yun Wu, Lei Cui, Hao-Jia Dong, Zhen Wang, Xiong Zhang, Jian-Hong Zhu

BMC Geriatr. 2022; 22: 427. Published online 2022 May 16. doi: 10.1186/s12877-022-03132-1

PMCID:: PMC9109383

Abstract Article PDF–4.4M

Select item 89506188.

Effect of ALDH1A1 Gene Knockout on Drug Resistance in Paclitaxel and Topotecan Resistant Human Ovarian Cancer Cell Lines in 2D and 3D Model

Marta Nowacka, Barbara Ginter-Matuszewska, Monika Świerczewska, Karolina Sterzyńska, Michał Nowicki, Radosław Januchowski

Int J Mol Sci. 2022 Mar; 23(6): 3036. Published online 2022 Mar 11. doi: 10.3390/ijms23063036

PMCID:: PMC8950618

Abstract Article PDF–4.0M

Select item 81849659.

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra

Sci Rep. 2021; 11: 11949. Published online 2021 Jun 7. doi: 10.1038/s41598-021-90570-3

PMCID:: PMC8184965

Abstract Article PDF–2.5M

Select item 805763610.

ALDH1A1 is a Marker of Astrocytic Differentiation during Brain Development and Correlates with Better Survival in Glioblastoma Patients

S. Alexandra Adam, Oliver Schnell, Julia Pöschl, Sabina Eigenbrod, Hans A. Kretzschmar, Jörg‐Christian Tonn, Ulrich Schüller

Brain Pathol. 2012 Nov; 22(6): 788–797. Published online 2012 Apr 19. doi: 10.1111/j.1750-3639.2012.00592.x

PMCID:: PMC8057636

Abstract Article PDF–3.7M

Select item 777474111.

Association study between genetic variants in retinol metabolism pathway genes and prostate cancer risk

Dongliang Cao, Yixuan Meng, Shuwei Li, Junyi Xin, Shuai Ben, Yifei Cheng, Meilin Wang, Lixin Hua, Gong Cheng

Cancer Med. 2020 Dec; 9(24): 9462–9470. Published online 2020 Oct 17. doi: 10.1002/cam4.3538

PMCID:: PMC7774741

Abstract Article PDF–585K

Select item 694687412.

ALDH1A1 contributes to PARP inhibitor resistance via enhancing DNA repair in BRCA2^−/− ovarian cancer cells

Lu Liu, Shurui Cai, Chunhua Han, Ananya Banerjee, Dayong Wu, Tiantian Cui, Guozhen Xie, Junran Zhang, Xiaoli Zhang, Eric McLaughlin, Ming Yin, Floor J. Backes, Arnab Chakravarti, Yanfang Zheng, Qi-En Wang

Mol Cancer Ther. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Mol Cancer Ther. 2020 Jan; 19(1): 199–210. Published online 2019 Sep 18. doi: 10.1158/1535-7163.MCT-19-0242

PMCID:: PMC6946874

Abstract Article PDF–2.5M

Select item 683129013.

Aldehyde dehydrogenase 1A1 confers erlotinib resistance via facilitating the reactive oxygen species-reactive carbonyl species metabolic pathway in lung adenocarcinomas

Hui-Min Lei, Ke-Ren Zhang, Cong Hui Wang, Yang Wang, Guang-Lei Zhuang, Li-Ming Lu, Jian Zhang, Ying Shen, Hong-Zhuan Chen, Liang Zhu

Theranostics. 2019; 9(24): 7122–7139. Published online 2019 Sep 23. doi: 10.7150/thno.35729

Correction in:: Theranostics. 2023; 13(7): 2257–2258.

PMCID:: PMC6831290

Abstract Article PDF–3.7M

Select item 681827914.

Androgen Receptor and ALDH1 Expression Among Internationally Diverse Patient Populations

Evelyn Jiagge, Aisha Souleiman Jibril, Melissa Davis, Carlos Murga-Zamalloa, Celina G. Kleer, Kofi Gyan, George Divine, Mark Hoenerhoff, Jessica Bensenhave, Baffour Awuah, Joseph Oppong, Ernest Adjei, Barbara Salem, Kathy Toy, Sofia Merajver, Max Wicha, Lisa Newman

J Glob Oncol. 2018; 4: JGO.18.00056. Published online 2018 Aug 11. doi: 10.1200/JGO.18.00056

PMCID:: PMC6818279

Abstract Article PDF–741K

Select item 611730615.

High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling

Donghyeok Kim, Bo-hyun Choi, In-geun Ryoo, Mi-Kyoung Kwak

Cell Death Dis. 2018 Sep; 9(9): 896. Published online 2018 Aug 30. doi: 10.1038/s41419-018-0903-4

PMCID:: PMC6117306

Abstract Article PDF–2.4M

Select item 600303816.

ALDH1A inhibition sensitizes colon cancer cells to chemotherapy

Z. Kozovska, A. Patsalias, V. Bajzik, E. Durinikova, L. Demkova, S. Jargasova, B. Smolkova, J. Plava, L. Kucerova, M. Matuskova

BMC Cancer. 2018; 18: 656. Published online 2018 Jun 15. doi: 10.1186/s12885-018-4572-6

PMCID:: PMC6003038

Abstract Article PDF–1.4M

Select item 596141617.

Expression of Aldehyde Dehydrogenase 1A1 (ALDH1A1) as a Prognostic Biomarker in Colorectal Cancer Using Immunohistochemistry

Wangshuo Yang, Yang Wang, Wei Wang, Zhuming Chen, Guang Bai

Med Sci Monit. 2018; 24: 2864–2872. Published online 2018 May 7. doi: 10.12659/MSM.910109

PMCID:: PMC5961416

Abstract Article PDF–2.3M

Select item 581732118.

Update of ALDH as a Potential Biomarker and Therapeutic Target for AML

Xiangchou Yang, Rongxin Yao, Hong Wang

Biomed Res Int. 2018; 2018: 9192104. Published online 2018 Jan 3. doi: 10.1155/2018/9192104

PMCID:: PMC5817321

Abstract Article PDF–646K

Select item 566602619.

Tumor endothelial cells with high aldehyde dehydrogenase activity show drug resistance

Kyoko Hida, Nako Maishi, Kosuke Akiyama, Hitomi Ohmura‐Kakutani, Chisaho Torii, Noritaka Ohga, Takahiro Osawa, Hiroshi Kikuchi, Hirofumi Morimoto, Masahiro Morimoto, Masanobu Shindoh, Nobuo Shinohara, Yasuhiro Hida

Cancer Sci. 2017 Nov; 108(11): 2195–2203. Published online 2017 Sep 17. doi: 10.1111/cas.13388

PMCID:: PMC5666026

Abstract Article PDF–1.4M

Select item 564579320.

Molecular Cloning and Oxidative Modification of Human Lens ALDH1A1: Implication in Impaired Detoxification of Lipid Aldehydes

Tianlin Xiao, Mohammad Shoeb, M. Saeed Siddiqui, Min Zhang, Kota V. Ramana, Satish K. Srivastava, Vasilis Vasiliou, Naseem H. Ansari

J Toxicol Environ Health A. Author manuscript; available in PMC 2017 Oct 18.

Published in final edited form as: J Toxicol Environ Health A. 2009; 72(9): 577–584. doi: 10.1080/15287390802706371

PMCID:: PMC5645793

Abstract Article PDF–1.2M

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