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Select item 105394651.

TRIM25 targets p300 for degradation

Seham Elabd, Eleonora Pauletto, Valeria Solozobova, Nils Eickhoff, Nuno Padrao, Wilbert Zwart, Christine Blattner

Life Sci Alliance. 2023 Dec; 6(12): e202301980. Published online 2023 Sep 28. doi: 10.26508/lsa.202301980

PMCID:: PMC10539465

Abstract Article PDF–3.5M

Select item 184062.

Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor α

Akira Orimo, Satoshi Inoue, Osamu Minowa, Nobuko Tominaga, Yasuhiro Tomioka, Miyuki Sato, Junko Kuno, Hisahiko Hiroi, Yoshihiko Shimizu, Masami Suzuki, Tetsuo Noda, Masami Muramatsu

Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21): 12027–12032. doi: 10.1073/pnas.96.21.12027

PMCID:: PMC18406

Abstract Article PDF–397K

Select item 59856633.

An integrated systems biology approach identifies TRIM25 as a key determinant of breast cancer metastasis

Logan A. Walsh, Mariano J. Alvarez, Erich Y. Sabio, Marsha Reyngold, Vladimir Makarov, Suranjit Mukherjee, Ken-Wing Lee, Alexis Desrichard, Sevin Turcan, Martin G. Dalin, Vinagolu K. Rajasekhar, Shuibing Chen, Linda T. Vahdat, Andrea Califano, Timothy A. Chan

Cell Rep. Author manuscript; available in PMC 2018 Jun 4.

Published in final edited form as: Cell Rep. 2017 Aug 15; 20(7): 1623–1640. doi: 10.1016/j.celrep.2017.07.052

PMCID:: PMC5985663

Abstract Article PDF–2.0M

Select item 40123904.

Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling

Akshay A. D'Cruz, Nadia J. Kershaw, Jessica J. Chiang, May K. Wang, Nicos A. Nicola, Jeffrey J. Babon, Michaela U. Gack, Sandra E. Nicholson

Biochem J. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Biochem J. 2013 Dec 1; 456(2): 231–240. doi: 10.1042/BJ20121425

PMCID:: PMC4012390

Abstract Article PDF–1.8M

Select item 479335.

Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein.

S Inoue, A Orimo, T Hosoi, S Kondo, H Toyoshima, T Kondo, A Ikegami, Y Ouchi, H Orimo, M Muramatsu

Proc Natl Acad Sci U S A. 1993 Dec 1; 90(23): 11117–11121. doi: 10.1073/pnas.90.23.11117

PMCID:: PMC47933

Summary Page Browse PDF–1.2M

Select item 84814846.

Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a

Chengcai Lai, Lihui Liu, Qinghua Liu, Keyu Wang, Sijie Cheng, Lingna Zhao, Min Xia, Cheng Wang, Yueqiang Duan, Lili Zhang, Ziyang Liu, Jianjun Luo, Xiliang Wang, Runsheng Chen, Penghui Yang

Cell Death Differ. 2021 Oct; 28(10): 2900–2915. Published online 2021 May 14. doi: 10.1038/s41418-021-00791-2

PMCID:: PMC8481484

Abstract Article PDF–4.0M

Select item 74427987.

OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity

Fangzhou Li, Qianqian Sun, Kun Liu, Ling Zhang, Ning Lin, Kaiqiang You, Mingwei Liu, Ning Kon, Feng Tian, Zebin Mao, Tingting Li, Tanjun Tong, Jun Qin, Wei Gu, Dawei Li, Wenhui Zhao

Nat Commun. 2020; 11: 4184. Published online 2020 Aug 21. doi: 10.1038/s41467-020-17926-7

PMCID:: PMC7442798

Abstract Article PDF–2.3M

Select item 35102538.

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

Ricardo Rajsbaum, Randy A. Albrecht, May K. Wang, Natalya P. Maharaj, Gijs A. Versteeg, Estanislao Nistal-Villán, Adolfo García-Sastre, Michaela U. Gack

PLoS Pathog. 2012 Nov; 8(11): e1003059. Published online 2012 Nov 29. doi: 10.1371/journal.ppat.1003059

PMCID:: PMC3510253

Abstract Article PDF–1.6M

Select item 68208719.

RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination

Kendra M. Quicke, Kristin Y. Kim, Curt M. Horvath, Mehul S. Suthar

J Interferon Cytokine Res. 2019 Nov 1; 39(11): 669–683. Published online 2019 Oct 29. doi: 10.1089/jir.2019.0059

PMCID:: PMC6820871

Abstract Article PDF–1.2M

Select item 575284110.

Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex

Bo Zhao, Weidao Zhang, Yixian Cun, Jingzheng Li, Yan Liu, Jing Gao, Hongwen Zhu, Hu Zhou, Rugang Zhang, Ping Zheng

Cell Res. 2018 Jan; 28(1): 69–89. Published online 2017 Nov 10. doi: 10.1038/cr.2017.139

PMCID:: PMC5752841

Abstract Article PDF–9.1M

Select item 645971811.

NLRP12 regulates anti-viral RIG-I activation via interaction with TRIM25

Szu-Ting Chen, Liang Chen, Diego Shih-Chieh Lin, Sei-Yi Chen, Yen-Po Tsao, Haitao Guo, Fei-Ju Li, Wei-Ting Tseng, Jason W. Tam, Chih-Wei Chao, W. June Brickey, Ivan Dzhagalov, Moon-Jung Song, Hye-Ri Kang, Jae U. Jung, Jenny P-Y Ting

Cell Host Microbe. Author manuscript; available in PMC 2020 Apr 10.

Published in final edited form as: Cell Host Microbe. 2019 Apr 10; 25(4): 602–616.e7. Published online 2019 Mar 19. doi: 10.1016/j.chom.2019.02.013

PMCID:: PMC6459718

Abstract Article PDF–3.0M

Select item 371235612.

Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I

Penghua Wang, Alvaro Arjona, Yue Zhang, Hameeda Sultana, Jianfeng Dai, Long Yang, Philippe M LeBlanc, Karine Doiron, Maya Saleh, Erol Fikrig

Nat Immunol. Author manuscript; available in PMC 2013 Jul 16.

Published in final edited form as: Nat Immunol. 2010 Oct; 11(10): 912–919. Published online 2010 Sep 5. doi: 10.1038/ni.1933

PMCID:: PMC3712356

Abstract Article PDF–3.9M

Select item 548461913.

Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses

Wei Liu, Jing Li, Weinan Zheng, Yingli Shang, Zhendong Zhao, Shanshan Wang, Yuhai Bi, Shuang Zhang, Chongfeng Xu, Ziyuan Duan, Lianfeng Zhang, Yue L Wang, Zhengfan Jiang, Wenjun Liu, Lei Sun

eLife. 2017; 6: e24425. Published online 2017 Jun 8. doi: 10.7554/eLife.24425

PMCID:: PMC5484619

Abstract Article PDF–6.5M

Select item 307048114.

Linear ubiquitin assembly complex negatively regulates RIG-I and TRIM25 mediated type-I interferon induction

Kyung-Soo Inn, Michaela U. Gack, Fuminori Tokunaga, Mude Shi, Lai-Yee Wong, Kazuhiro Iwai, Jae U. Jung

Mol Cell. Author manuscript; available in PMC 2012 Feb 4.

Published in final edited form as: Mol Cell. 2011 Feb 4; 41(3): 354–365. doi: 10.1016/j.molcel.2010.12.029

PMCID:: PMC3070481

Abstract Article PDF–1.8M

Select item 222295415.

TRIM E3 Ligases Interfere with Early and Late Stages of the Retroviral Life Cycle

Pradeep D Uchil, Brian D Quinlan, Wai-Tsing Chan, Joseph M Luna, Walther Mothes

PLoS Pathog. 2008 Feb; 4(2): e16. Published online 2008 Feb 1. doi: 10.1371/journal.ppat.0040016

PMCID:: PMC2222954

Abstract Article PDF–1.0M

Select item 12524516.

The tripartite motif family identifies cell compartments

Alexandre Reymond, Germana Meroni, Anna Fantozzi, Giuseppe Merla, Stefano Cairo, Lucilla Luzi, Daniela Riganelli, Elena Zanaria, Silvia Messali, Silvia Cainarca, Alessandro Guffanti, Saverio Minucci, Pier Giuseppe Pelicci, Andrea Ballabio

EMBO J. 2001 May 1; 20(9): 2140–2151. doi: 10.1093/emboj/20.9.2140

PMCID:: PMC125245

Abstract Article PDF–787K

Select item 660230017.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 645951018.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 633346019.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327