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Select item 77015851.

Loss of TG‐Interacting Factor 1 decreases survival in mouse models of myeloid leukaemia

Ling Yan, Utpal P. Davé, Michael Engel, Stephen J. Brandt, Rizwan Hamid

J Cell Mol Med. 2020 Nov; 24(22): 13472–13480. Published online 2020 Oct 15. doi: 10.1111/jcmm.15977

PMCID:: PMC7701585

Abstract Article PDF–939K

Select item 38895552.

Tgif1 Regulates Quiescence and Self-Renewal of Hematopoietic Stem Cells

Ling Yan, Bethany Womack, David Wotton, Yan Guo, Yu Shyr, Utpal Davé, Chun Li, Scott Hiebert, Stephen Brandt, Rizwan Hamid

Mol Cell Biol. 2013 Dec; 33(24): 4824–4833. doi: 10.1128/MCB.01076-13

PMCID:: PMC3889555

Abstract Article PDF–1.2M

Select item 33423053.

The TGF-β/Smad Repressor TG-Interacting Factor 1 (TGIF1) Plays a Role in Radiation-Induced Intestinal Injury Independently of a Smad Signaling Pathway

Mohammad Hneino, Agnes François, Valerie Buard, Georges Tarlet, Rym Abderrahmani, Karl Blirando, Pamela A. Hoodless, Marc Benderitter, Fabien Milliat

PLoS One. 2012; 7(5): e35672. Published online 2012 May 2. doi: 10.1371/journal.pone.0035672

PMCID:: PMC3342305

Abstract Article PDF–1.9M

Select item 29399154.

Tgif1 represses apolipoprotein gene expression in liver

Tiffany A. Melhuish, David D. Chung, Glen A. Bjerke, David Wotton

J Cell Biochem. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: J Cell Biochem. 2010 Oct 1; 111(2): 380–390. doi: 10.1002/jcb.22713

PMCID:: PMC2939915

Abstract Article PDF–1.1M

Select item 110452215.

Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

Simona Bolamperti, Hiroaki Saito, Sarah Heerdmann, Eric Hesse, Hanna Taipaleenmäki

eLife. 2024; 13: RP94265. Published online 2024 Apr 25. doi: 10.7554/eLife.94265

PMCID:: PMC11045221

Abstract Article PDF–17M

Select item 71468746.

Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment

Marie-Therese Haider, Hiroaki Saito, Jennifer Zarrer, Kevin Uzhunnumpuram, Sankari Nagarajan, Vijayalakshmi Kari, Michael Horn-Glander, Stefan Werner, Eric Hesse, Hanna Taipaleenmäki

Breast Cancer Res. 2020; 22: 34. Published online 2020 Apr 9. doi: 10.1186/s13058-020-01269-8

PMCID:: PMC7146874

Abstract Article PDF–4.1M

Select item 65960197.

Canonical TGF-β Signaling Negatively Regulates Neuronal Morphogenesis through TGIF/Smad Complex-Mediated CRMP2 Suppression

Hideyuki Nakashima, Keita Tsujimura, Koichiro Irie, Masataka Ishizu, Miao Pan, Tomonori Kameda, Kinichi Nakashima

J Neurosci. 2018 May 16; 38(20): 4791–4810. doi: 10.1523/JNEUROSCI.2423-17.2018

PMCID:: PMC6596019

Abstract Article PDF–8.4M

Select item 55807108.

HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets

Bony De Kumar, Hugo J. Parker, Ariel Paulson, Mark E. Parrish, Irina Pushel, Narendra Pratap Singh, Ying Zhang, Brian D. Slaughter, Jay R. Unruh, Laurence Florens, Julia Zeitlinger, Robb Krumlauf

Genome Res. 2017 Sep; 27(9): 1501–1512. doi: 10.1101/gr.219386.116

PMCID:: PMC5580710

Abstract Article PDF–18M

Select item 36747969.

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease

Hilda Tateossian, Susan Morse, Andrew Parker, Philomena Mburu, Nick Warr, Abraham Acevedo-Arozena, Michael Cheeseman, Sara Wells, Steve D.M. Brown

Hum Mol Genet. 2013 Jul 1; 22(13): 2553–2565. Published online 2013 Mar 3. doi: 10.1093/hmg/ddt103

PMCID:: PMC3674796

Abstract Article PDF–1.1M

Select item 251723110.

Maternal Tgif is required for vascularization of the embryonic placenta

Laurent Bartholin, Tiffany A. Melhuish, Shannon E. Powers, Sophie Goddard-Léon, Isabelle Treilleux, Ann E. Sutherland, David Wotton

Dev Biol. Author manuscript; available in PMC 2009 Jul 15.

Published in final edited form as: Dev Biol. 2008 Jul 15; 319(2): 285–297. Published online 2008 May 2. doi: 10.1016/j.ydbio.2008.04.027

PMCID:: PMC2517231

Abstract Article PDF–5.2M

Select item 148908011.

Embryonic Fibroblasts from Mice Lacking Tgif Were Defective in Cell Cycling

Lynn Mar, Pamela A. Hoodless

Mol Cell Biol. 2006 Jun; 26(11): 4302–4310. doi: 10.1128/MCB.02156-05

PMCID:: PMC1489080

Abstract Article PDF–618K

Select item 644654312.

TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth

Anant Shah, Tiffany A. Melhuish, Todd E. Fox, Henry F. Frierson, Jr, David Wotton

Genes Dev. 2019 Apr 1; 33(7-8): 388–402. doi: 10.1101/gad.320127.118

PMCID:: PMC6446543

Abstract Article PDF–12M

Select item 396670413.

TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2

Camilla Pramfalk, Tiffany A. Melhuish, David Wotton, Zhao-Yan Jiang, Mats Eriksson, Paolo Parini

J Lipid Res. 2014 Apr; 55(4): 709–717. doi: 10.1194/jlr.M045922

PMCID:: PMC3966704

Abstract Article PDF–905K

Select item 270455114.

The nigrostriatal dopamine system of aging GFRα-1 heterozygous mice: neurochemistry, morphology and behavior

Vandana Zaman, Heather A. Boger, Ann-Charlotte Granholm, Baerbel Rohrer, Alfred Moore, Mona Buhusi, Greg A. Gerhardt, Barry J. Hoffer, Lawrence D. Middaugh

Eur J Neurosci. Author manuscript; available in PMC 2009 Jul 1.

Published in final edited form as: Eur J Neurosci. 2008 Oct; 28(8): 1557–1568. doi: 10.1111/j.1460-9568.2008.06456.x

PMCID:: PMC2704551

Abstract Article PDF–2.8M

Select item 964142415.

Antagonizing microRNA‐19a/b augments PTH anabolic action and restores bone mass in osteoporosis in mice

Hanna Taipaleenmäki, Hiroaki Saito, Saskia Schröder, Miki Maeda, Ramona Mettler, Matthias Ring, Ewa Rollmann, Andreas Gasser, Carl Haasper, Thorsten Gehrke, Alexander Weiss, Steffen K Grimm, Eric Hesse

EMBO Mol Med. 2022 Nov; 14(11): e13617. Published online 2022 Oct 4. doi: 10.15252/emmm.202013617

PMCID:: PMC9641424

Abstract Article PDF–3.0M

Select item 643077316.

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

Hiroaki Saito, Andreas Gasser, Simona Bolamperti, Miki Maeda, Levi Matthies, Katharina Jähn, Courtney L. Long, Hartmut Schlüter, Marcel Kwiatkowski, Vaibhav Saini, Paola Divieti Pajevic, Teresita Bellido, Andre J. van Wijnen, Khalid S. Mohammad, Theresa A. Guise, Hanna Taipaleenmäki, Eric Hesse

Nat Commun. 2019; 10: 1354. Published online 2019 Mar 22. doi: 10.1038/s41467-019-08778-x

PMCID:: PMC6430773

Abstract Article PDF–2.4M

Select item 472833217.

A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse

Derek Hood, Richard Moxon, Tom Purnell, Caroline Richter, Debbie Williams, Ali Azar, Michael Crompton, Sara Wells, Martin Fray, Steve D. M. Brown, Michael T. Cheeseman

Dis Model Mech. 2016 Jan 1; 9(1): 69–79. doi: 10.1242/dmm.021659

PMCID:: PMC4728332

Abstract Article

Select item 349393218.

The TG-interacting Factor TGIF1 Regulates Stress-induced Proinflammatory Phenotype of Endothelial Cells

Mohammad Hneino, Karl Blirando, Valérie Buard, Georges Tarlet, Marc Benderitter, Pamela Hoodless, Agnès François, Fabien Milliat

J Biol Chem. 2012 Nov 9; 287(46): 38913–38921. Published online 2012 Sep 20. doi: 10.1074/jbc.M112.388389

PMCID:: PMC3493932

Abstract Article PDF–1.6M

Select item 182076319.

Functional analysis of mutations in TGIF associated with holoprosencephaly

Kenia B. El-Jaick, Shannon E. Powers, Laurent Bartholin, Kenneth R. Myers, Jin Hahn, Ieda M. Orioli, Maia Ouspenskaia, Felicitas Lacbawan, Erich Roessler, David Wotton, Maximilian Muenke

Mol Genet Metab. Author manuscript; available in PMC 2007 Mar 12.

Published in final edited form as: Mol Genet Metab. 2007 Jan; 90(1): 97–111. Published online 2006 Sep 7. doi: 10.1016/j.ymgme.2006.07.011