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Select item 104492831.

TIMP2 facilitates CIRI through activating NLRP3-mediated pyroptosis

Shaoyong Shi, Chongyang Zhang, Jiaxiang Liu

Aging (Albany NY) 2023 May 15; 15(9): 3635–3643. Published online 2023 May 12. doi: 10.18632/aging.204696

PMCID:: PMC10449283

Abstract Article PDF–914K

Select item 102754012.

Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging

Rachel Britton, Tristan Wasley, Reema Harish, Charles Holz, John Hall, Dennis C. Yee, Jody Melton Witt, Elizabeth A. Booth, Steven Braithwaite, Eva Czirr, Meghan Kerrisk Campbell

eNeuro. 2023 Jun; 10(6): ENEURO.0031-23.2023. Published online 2023 Jun 12. doi: 10.1523/ENEURO.0031-23.2023

PMCID:: PMC10275401

Abstract Article PDF–2.7M

Select item 72215063.

TIMP-2 suppresses tumor growth and metastasis in murine model of triple-negative breast cancer

David Peeney, Sandra M Jensen, Nadia P Castro, Sarvesh Kumar, Silvia Noonan, Chenchen Handler, Alex Kuznetsov, Joanna Shih, Andy D Tran, David S Salomon, William G Stetler-Stevenson

Carcinogenesis. 2020 May; 41(3): 313–325. Published online 2019 Oct 17. doi: 10.1093/carcin/bgz172

PMCID:: PMC7221506

Abstract Article PDF–60M

Select item 63216664.

Anti-cancer effect of dung beetle glycosaminoglycans on melanoma

Mi Young Ahn, Ban Ji Kim, Ha Jeong Kim, Jang Mi Jin, Hyung Joo Yoon, Jae Sam Hwang, Kun-Koo Park

BMC Cancer. 2019; 19: 9. Published online 2019 Jan 5. doi: 10.1186/s12885-018-5202-z

PMCID:: PMC6321666

Abstract Article PDF–1.9M

Select item 40005635.

Angiotensin-II Induced Hypertension and Renovascular Remodeling in TIMP2 Knockout Mice

Sathnur PUSHPAKUMAR, Sourav KUNDU, Tyranny PRYOR, Srikanth GIVVIMANI, Eleanor LEDERER, Suresh C. TYAGI, Utpal SEN

J Hypertens. Author manuscript; available in PMC 2014 Apr 26.

Published in final edited form as: J Hypertens. 2013 Nov; 31(11): 2270–2281. doi: 10.1097/HJH.0b013e3283649b33

PMCID:: PMC4000563

Abstract Article PDF–2.1M

Select item 30606276.

Sexually Dimorphic Diet-Induced Insulin Resistance in Obese Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)-Deficient Mice

Diane M. Jaworski, Olga Sideleva, Holly M. Stradecki, Garret D. Langlois, Aida Habibovic, Basanthi Satish, William G. Tharp, James Lausier, Kyla LaRock, Thomas L. Jetton, Mina Peshavaria, Richard E. Pratley

Endocrinology. 2011 Apr; 152(4): 1300–1313. Published online 2011 Feb 1. doi: 10.1210/en.2010-1029

PMCID:: PMC3060627

Abstract Article

Select item 30424797.

Hyperphagia and leptin resistance in Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) deficient mice

Holly M. Stradecki, Diane M. Jaworski

J Neuroendocrinol. Author manuscript; available in PMC 2012 Mar 1.

Published in final edited form as: J Neuroendocrinol. 2011 Mar; 23(3): 269–281. doi: 10.1111/j.1365-2826.2010.02105.x

PMCID:: PMC3042479

Abstract Article PDF–1.2M

Select item 111594758.

Substrate choice of membrane‐type 1 matrix metalloproteinase is dictated by tissue inhibitor of metalloproteinase‐2 levels

Tomoya Kudo, Takahisa Takino, Hisashi Miyamori, Erik W. Thompson, Hiroshi Sato

Cancer Sci. 2007 Apr; 98(4): 563–568. Published online 2007 Feb 12. doi: 10.1111/j.1349-7006.2007.00426.x

PMCID:: PMC11159475

Abstract Article PDF–530K

Select item 107304009.

Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity

Ana Catarina Ferreira, Brittany M. Hemmer, Sarah M. Philippi, Alejandro B. Grau-Perales, Jacob L. Rosenstadt, Hanxiao Liu, Jeffrey D. Zhu, Tatyana Kareva, Tim Ahfeldt, Merina Varghese, Patrick R. Hof, Joseph M. Castellano

Mol Psychiatry. 2023; 28(9): 3943–3954. Published online 2023 Nov 2. doi: 10.1038/s41380-023-02296-5

PMCID:: PMC10730400

Abstract Article PDF–3.6M

Select item 511392410.

Aberrant Expression of TIMP-2 and PBEF Genes in the Placentae of Cloned Mice Due to Epigenetic Reprogramming Error

Hong Rye Kim, Jae Eun Lee, Reza Kheirkhahi Oqani, So Yeon Kim, Teruhiko Wakayama, Chong Li, Su Jin Sa, Je Seok Woo, Dong Il Jin

PLoS One. 2016; 11(11): e0166241. Published online 2016 Nov 17. doi: 10.1371/journal.pone.0166241

PMCID:: PMC5113924

Abstract Article PDF–1.6M

Select item 388136311.

TIMP-2 mutant decreases MMP-2 activity and augments pressure overload induced LV dysfunction and heart failure

S. Givvimani, S. Kundu, N. Narayanan, F. Armaghan, N. Qipshidze, S. Pushpakumar, T. P. Vacek, S. C. Tyagi

Arch Physiol Biochem. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Arch Physiol Biochem. 2013 May; 119(2): 10.3109/13813455.2012.755548. Published online 2013 Feb 11. doi: 10.3109/13813455.2012.755548

PMCID:: PMC3881363

Abstract Article PDF–2.1M

Select item 312069612.

A dual role for microglia in promoting tissue inhibitor of metalloproteinase (TIMP) expression in glial cells in response to neuroinflammatory stimuli

Jennifer V Welser-Alves, Stephen J Crocker, Richard Milner

J Neuroinflammation. 2011; 8: 61. Published online 2011 Jun 1. doi: 10.1186/1742-2094-8-61

PMCID:: PMC3120696

Abstract Article PDF–2.0M

Select item 298221213.

Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates neuromuscular junction development via a β1 integrin-mediated mechanism

Gentian Lluri, Garret D. Langlois, Brian McClellan, Paul D. Soloway, Diane M. Jaworski

J Neurobiol. Author manuscript; available in PMC 2010 Nov 16.

Published in final edited form as: J Neurobiol. 2006 Oct 1; 66(12): 1365–1377. doi: 10.1002/neu.20315

PMCID:: PMC2982212

Abstract Article PDF–1.6M

Select item 297869514.

Functional Genomics Complements Quantitative Genetics in Identifying Disease-Gene Associations

Yuanfang Guan, Cheryl L. Ackert-Bicknell, Braden Kell, Olga G. Troyanskaya, Matthew A. Hibbs

PLoS Comput Biol. 2010 Nov; 6(11): e1000991. Published online 2010 Nov 11. doi: 10.1371/journal.pcbi.1000991

PMCID:: PMC2978695

Abstract Article PDF–1.0M

Select item 271531615.

Tissue Inhibitor of Metalloproteinase-1 Deficiency Amplifies Acute Lung Injury in Bleomycin-Exposed Mice

Kyoung-Hee Kim, Kristin Burkhart, Peter Chen, Charles W. Frevert, Julie Randolph-Habecker, Robert C. Hackman, Paul D. Soloway, David K. Madtes

Am J Respir Cell Mol Biol. 2005 Sep; 33(3): 271–279. Published online 2005 Jun 9. doi: 10.1165/rcmb.2005-0111OC

PMCID:: PMC2715316

Abstract Article PDF–477K

Select item 268306816.

TIMP-2 Is Required for Efficient Activation of proMMP-2 in Vivo

Zhiping Wang, Ruth Juttermann, Paul D. Soloway

J Biol Chem. Author manuscript; available in PMC 2009 May 16.

Published in final edited form as: J Biol Chem. 2000 Aug 25; 275(34): 26411–26415. doi: 10.1074/jbc.M001270200

PMCID:: PMC2683068

Abstract Article PDF–730K

Select item 219716117.

Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) regulates myogenesis and β1 integrin expression in vitro

Gentian Lluri, Garret D. Langlois, Paul D. Soloway, Diane M. Jaworski

Exp Cell Res. Author manuscript; available in PMC 2009 Jan 1.

Published in final edited form as: Exp Cell Res. 2008 Jan 1; 314(1): 11–24. Published online 2007 Jun 27. doi: 10.1016/j.yexcr.2007.06.007

PMCID:: PMC2197161

Abstract Article PDF–1.1M

Select item 592598918.

Differential Regulation of MMP‐9 and TIMP‐2 Expression in Malignant Melanoma Developed in Metallothionein/RET Transgenic Mice

Masami Asai, Masashi Kato, Naoya Asai, Toshihide Iwashita, Hideki Murakami, Kumi Kawai, Izumi Nakashima, Masahide Takahashi1

Jpn J Cancer Res. 1999 Jan; 90(1): 86–92. doi: 10.1111/j.1349-7006.1999.tb00670.x

PMCID:: PMC5925989

Summary PDF–3.7M

Select item 558622219.

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

Joseph M. Castellano, Kira I. Mosher, Rachelle J. Abbey, Alisha A. McBride, Michelle L. James, Daniela Berdnik, Jadon C. Shen, Bende Zou, Xinmin S. Xie, Martha Tingle, Izumi V. Hinkson, Martin S. Angst, Tony Wyss-Coray

Nature. Author manuscript; available in PMC 2017 Oct 27.

Published in final edited form as: Nature. 2017 Apr 27; 544(7651): 488–492. Published online 2017 Apr 19. doi: 10.1038/nature22067