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Select item 112961161.

Chronic TNF exposure induces glucocorticoid‐like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia

Katherine L. Kruckow, Elizabeth Murray, Elnur Shayhidin, Alexander F. Rosenberg, Dawn M. E. Bowdish, Carlos J. Orihuela

Aging Cell. 2024 Jun; 23(6): e14133. Published online 2024 Mar 8. doi: 10.1111/acel.14133

PMCID:: PMC11296116

Abstract Article PDF–4.1M

Select item 108989402.

TNF-α protects from exacerbated myocarditis and cardiac death by suppressing expansion of activated heart-reactive CD4⁺ T cells

Filip Rolski, Karolina Tkacz, Kazimierz Węglarczyk, Grzegorz Kwiatkowski, Paweł Pelczar, Agnieszka Jaźwa-Kusior, Anna Bar, Gabriela M Kuster, Stefan Chłopicki, Maciej Siedlar, Gabriela Kania, Przemysław Błyszczuk

Cardiovasc Res. 2024 Jan; 120(1): 82–94. Published online 2023 Oct 25. doi: 10.1093/cvr/cvad158

PMCID:: PMC10898940

Abstract Article PDF–1.3M

Select item 108336063.

TNF-α from the Proximal Nephron Exacerbates Aristolochic Acid Nephropathy

Yi Wen, Xiaohan Lu, Jamie R. Privratsky, Jiafa Ren, Saba Ali, Bo Yang, Nathan P. Rudemiller, Jiandong Zhang, Sergei A. Nedospasov, Steven D. Crowley

Kidney360. 2024 Jan; 5(1): 44–56. Published online 2023 Nov 21. doi: 10.34067/KID.0000000000000314

PMCID:: PMC10833606

Abstract Article PDF–1.3M

Select item 108168994.

Knockout of the Tnfa Gene Decreases Influenza Virus-Induced Histological Reactions in Laboratory Mice

Darya A. Savenkova, Andrey S. Gudymo, Alexey N. Korablev, Oleg S. Taranov, Darya V. Bazovkina, Nataliya V. Danilchenko, Olga N. Perfilyeva, Elena K. Ivleva, Anastasiya A. Moiseeva, Yulia A. Bulanovich, Elena V. Roshchina, Irina A. Serova, Nariman R. Battulin, Elizabeth A. Kulikova, Dmitry V. Yudkin

Int J Mol Sci. 2024 Jan; 25(2): 1156. Published online 2024 Jan 18. doi: 10.3390/ijms25021156

PMCID:: PMC10816899

Abstract Article PDF–1.0M

Select item 104936005.

TNFα is a key trigger of inflammation in diet-induced non-obese MASLD in mice

Katharina Burger, Finn Jung, Anja Baumann, Annette Brandt, Raphaela Staltner, Victor Sánchez, Ina Bergheim

Redox Biol. 2023 Oct; 66: 102870. Published online 2023 Sep 1. doi: 10.1016/j.redox.2023.102870

PMCID:: PMC10493600

Abstract Article PDF–6.9M

Select item 104336916.

The TNF^ΔARE Mouse as a Model of Intestinal Fibrosis

Calen A. Steiner, Samuel D. Koch, Tamara Evanoff, Nichole Welch, Rachael Kostelecky, Rosemary Callahan, Emily M. Murphy, Tom T. Nguyen, Caroline H.T. Hall, Sizhao Lu, Edwin F. de Zoeten, Mary C.M. Weiser-Evans, Ian M. Cartwright, Sean P. Colgan

Am J Pathol. 2023 Aug; 193(8): 1013–1028. doi: 10.1016/j.ajpath.2023.04.009

PMCID:: PMC10433691

Abstract Article PDF–5.6M

Select item 101527597.

Acute coronavirus infection triggers a TNF-dependent osteoporotic phenotype in mice

Celso M. Queiroz-Junior, Anna C.P.M. Santos, Matheus R. Gonçalves, Camila B. Brito, Breno Barrioni, Pedro J. Almeida, Marcela H. Gonçalves-Pereira, Tarcília Silva, Sicília R. Oliveira, Marivalda M. Pereira, Helton C. Santiago, Mauro M. Teixeira, Vivian V. Costa

Life Sci. 2023 Jul 1; 324: 121750. Published online 2023 May 2. doi: 10.1016/j.lfs.2023.121750

PMCID:: PMC10152759

Abstract Article PDF–13M

Select item 95403108.

Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis‐linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice

Brigid K. Jensen, Kevin J. McAvoy, Nicolette M. Heinsinger, Angelo C. Lepore, Hristelina Ilieva, Aaron R. Haeusler, Davide Trotti, Piera Pasinelli

Glia. 2022 Jul; 70(7): 1426–1449. Published online 2022 Apr 26. doi: 10.1002/glia.24183

PMCID:: PMC9540310

Abstract Article PDF–6.2M

Select item 89987979.

TNF-α Induced Myotube Atrophy in C2C12 Cell Line Uncovers Putative Inflammatory-Related lncRNAs Mediating Muscle Wasting

Tomasz Powrózek, Dominika Pigoń-Zając, Marcin Mazurek, Michael Ochieng Otieno, Mansur Rahnama-Hezavah, Teresa Małecka-Massalska

Int J Mol Sci. 2022 Apr; 23(7): 3878. Published online 2022 Mar 31. doi: 10.3390/ijms23073878

PMCID:: PMC8998797

Abstract Article PDF–5.9M

Select item 880482610.

Low-Frequency Vibration Promotes Tumor Necrosis Factor-α Production to Increase Cartilage Degeneration in Knee Osteoarthritis

Peng-Ming Yu, Yang Lin, Chi Zhang, Hai-Ming Wang, Quan Wei, Si-Yi Zhu, Qing-Chuan Wei, Zhi-Gang Wang, Hong-Xia Pan, Ri-Dong Huang, Cheng-Qi He

Cartilage. 2021 Dec; 13(2 Suppl): 1398S–1406S. Published online 2020 Jun 12. doi: 10.1177/1947603520931178

PMCID:: PMC8804826

Abstract Article PDF–912K

Select item 861832011.

Scavenging Tumor Necrosis Factor α Does Not Affect Inhibition of Dentate Granule Cells Following In Vitro Entorhinal Cortex Lesion

Dimitrios Kleidonas, Andreas Vlachos

Cells. 2021 Nov; 10(11): 3232. Published online 2021 Nov 19. doi: 10.3390/cells10113232

PMCID:: PMC8618320

Abstract Article PDF–3.0M

Select item 858102712.

Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine

Teresa Canedo, Camila Cabral Portugal, Renato Socodato, Tiago Oliveira Almeida, Ana Filipa Terceiro, Joana Bravo, Ana Isabel Silva, João Duarte Magalhães, Sónia Guerra-Gomes, João Filipe Oliveira, Nuno Sousa, Ana Magalhães, João Bettencourt Relvas, Teresa Summavielle

Neuropsychopharmacology. 2021 Dec; 46(13): 2358–2370. Published online 2021 Aug 16. doi: 10.1038/s41386-021-01139-7

PMCID:: PMC8581027

Abstract Article PDF–5.3M

Select item 846191813.

Intracolic ultrasound molecular imaging: a novel method for assessing colonic tumor necrosis factor-α expression in inflammatory bowel disease

Xiaoyan Miao, Ren Mao, Yujia You, Huichao Zhou, Chen Qiu, Xuehua Li, Zhihui Chen, Jie Ren, Minhu Chen, Ping Wang, Rongqin Zheng, Tinghui Yin

Mol Med. 2021; 27: 119. Published online 2021 Sep 23. doi: 10.1186/s10020-021-00379-z

PMCID:: PMC8461918

Abstract Article PDF–3.1M

Select item 813791814.

TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread

Jennifer Oyler-Yaniv, Alon Oyler-Yaniv, Evan Maltz, Roy Wollman

Nat Commun. 2021; 12: 2992. Published online 2021 May 20. doi: 10.1038/s41467-021-23195-9

PMCID:: PMC8137918

Abstract Article PDF–1.7M

Select item 800221715.

Tumor Necrosis Factor (TNF) Is Required for Spatial Learning and Memory in Male Mice under Physiological, but Not Immune-Challenged Conditions

Leda Mygind, Marianne Skov-Skov Bergh, Vivien Tejsi, Ramanan Vaitheeswaran, Kate L. Lambertsen, Bente Finsen, Athanasios Metaxas

Cells. 2021 Mar; 10(3): 608. Published online 2021 Mar 9. doi: 10.3390/cells10030608

PMCID:: PMC8002217

Abstract Article PDF–2.1M

Select item 769219716.

Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice

Ditte Gry Ellman, Minna Christiansen Lund, Maiken Nissen, Pernille Sveistrup Nielsen, Charlotte Sørensen, Emilie Boye Lester, Estrid Thougaard, Louise Helskov Jørgensen, Sergei A. Nedospasov, Ditte Caroline Andersen, Jane Stubbe, Roberta Brambilla, Matilda Degn, Kate Lykke Lambertsen

Cells. 2020 Nov; 9(11): 2407. Published online 2020 Nov 3. doi: 10.3390/cells9112407

PMCID:: PMC7692197

Abstract Article PDF–3.2M

Select item 753740217.

Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis

Merlijn H. Kaaij, Melissa N. van Tok, Iris C. Blijdorp, Carmen A. Ambarus, Michael Stock, Désiree Pots, Véronique L. Knaup, Marietta Armaka, Eleni Christodoulou-Vafeiadou, Tessa K. van Melsen, Huriatul Masdar, Harry J.P.P. Eskes, Nataliya G. Yeremenko, George Kollias, Georg Schett, Sander W. Tas, Leonie M. van Duivenvoorde, Dominique L.P. Baeten

J Exp Med. 2020 Oct 5; 217(10): e20200288. Published online 2020 Jul 14. doi: 10.1084/jem.20200288

PMCID:: PMC7537402

Abstract Article PDF–5.7M

Select item 735493618.

TNF deficiency dysregulates inflammatory cytokine production, leading to lung pathology and death during respiratory poxvirus infection

Ma. Junaliah Tuazon Kels, Esther Ng, Zahrah Al Rumaih, Pratikshya Pandey, Sigrid R. Ruuls, Heinrich Korner, Timothy P. Newsome, Geeta Chaudhri, Gunasegaran Karupiah

Proc Natl Acad Sci U S A. 2020 Jul 7; 117(27): 15935–15946. Published online 2020 Jun 22. doi: 10.1073/pnas.2004615117

PMCID:: PMC7354936

Abstract Article PDF–2.8M

Select item 730682619.

Effects of Tumor Necrosis Factor on Viral Replication and Pulmonary Inflammation during Acute Mouse Adenovirus Type 1 Respiratory Infection

Krittika Pant, Adithya Chandrasekaran, Christine J. Chang, Aditya Vageesh, Alexandra J. Popkov, Jason B. Weinberg

Virology. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: Virology. 2020 Aug; 547: 12–19. Published online 2020 May 23. doi: 10.1016/j.virol.2020.05.004

PMCID:: PMC7306826

Abstract Article PDF–1.1M

Select item 726957720.

Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia

Nimitha R. Mathew, Janaki M. Vinnakota, Petya Apostolova, Daniel Erny, Shaimaa Hamarsheh, Geoffroy Andrieux, Jung-Seok Kim, Kathrin Hanke, Tobias Goldmann, Louise Chappell-Maor, Nadia El-Khawanky, Gabriele Ihorst, Dominik Schmidt, Justus Duyster, Jürgen Finke, Thomas Blank, Melanie Boerries, Bruce R. Blazar, Steffen Jung, Marco Prinz, Robert Zeiser

J Clin Invest. 2020 Mar 2; 130(3): 1315–1329. Published online 2020 Feb 17. doi: 10.1172/JCI130272