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Items: 1 to 20 of 113

1.
CD137 Regulates Bone Loss via the p53 Wnt/β-Catenin Signaling Pathways in Aged Mice
Jiyu Han, Yanhong Wang, Haichao Zhou, Yingqi Zhang, Daqian Wan
Front Endocrinol (Lausanne) 2022; 13: 922501. Published online 2022 Jun 30. doi: 10.3389/fendo.2022.922501
PMCID:
PMC9279613
AbstractArticlePDF–7.9M
2.
CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation
Itziar Otano, Arantza Azpilikueta, Javier Glez-Vaz, Maite Alvarez, José Medina-Echeverz, Ivan Cortés-Domínguez, Carlos Ortiz-de-Solorzano, Peter Ellmark, Sara Fritzell, Gabriela Hernandez-Hoyos, Michelle Hase Nelson, María Carmen Ochoa, Elixabet Bolaños, Doina Cuculescu, Patricia Jaúregui, Sandra Sanchez-Gregorio, Iñaki Etxeberria, María E. Rodriguez-Ruiz, Miguel F. Sanmamed, Álvaro Teijeira, Pedro Berraondo, Ignacio Melero
Nat Commun. 2021; 12: 7296. Published online 2021 Dec 15. doi: 10.1038/s41467-021-27613-w
PMCID:
PMC8674279
AbstractArticlePDF–4.6M
3.
Activation of 4-1BB signaling in bone marrow stromal cells triggers bone loss via the p-38 MAPK-DKK1 axis in aged mice
Daqian Wan, Songtao Ai, Huoniu Ouyang, Liming Cheng
Exp Mol Med. 2021 Apr; 53(4): 654–666. Published online 2021 Apr 15. doi: 10.1038/s12276-021-00605-y
PMCID:
PMC8102492
AbstractArticlePDF–2.1M
4.
4-1BBL regulates the polarization of macrophages and inhibition of 4-1BBL signaling alleviates imiquimod-induced psoriasis
Haruka Miki, Kyung Ho Han, David Scott, Michael Croft, Young Jun Kang
J Immunol. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: J Immunol. 2020 Apr 1; 204(7): 1892–1903. Published online 2020 Feb 10. doi: 10.4049/jimmunol.1900983
PMCID:
PMC7313554
AbstractArticlePDF–1.5M
5.
Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci
Maria M. Xu, Antoine Ménoret, Sarah-Anne E. Nicholas, Sebastian Günther, Eric J. Sundberg, Beiyan Zhou, Annabelle Rodriguez, Patrick A. Murphy, Anthony T. Vella
Am J Physiol Heart Circ Physiol. 2019 Jun 1; 316(6): H1480–H1494. Published online 2019 Apr 12. doi: 10.1152/ajpheart.00088.2019
PMCID:
PMC6620679
AbstractArticle
6.
CD137 promotes bone metastasis of breast cancer by enhancing the migration and osteoclast differentiation of monocytes/macrophages
Pengling Jiang, Wenjuan Gao, Tiansi Ma, Rongrong Wang, Yongjun Piao, Xiaoli Dong, Peng Wang, Xuehui Zhang, Yanhua Liu, Weijun Su, Rong Xiang, Jin Zhang, Na Li
Theranostics. 2019; 9(10): 2950–2966. Published online 2019 May 9. doi: 10.7150/thno.29617
PMCID:
PMC6568184
AbstractArticlePDF–2.6M
7.
4-1BB Signaling Promotes Alveolar Macrophages-Mediated Pro-Fibrotic Responses and Crystalline Silica-Induced Pulmonary Fibrosis in Mice
Yiping Lu, Chao Li, Sitong Du, Xi Chen, Xinning Zeng, Fangwei Liu, Ying Chen, Jie Chen
Front Immunol. 2018; 9: 1848. Published online 2018 Sep 10. doi: 10.3389/fimmu.2018.01848
PMCID:
PMC6139304
AbstractArticlePDF–5.8M
8.
4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8+ T cell proliferation
Beom K Choi, Do Y Lee, Don G Lee, Young H Kim, Seon-Hee Kim, Ho S Oh, Chungyong Han, Byoung S Kwon
Cell Mol Immunol. 2017 Sep; 14(9): 748–757. Published online 2016 Mar 14. doi: 10.1038/cmi.2016.02
PMCID:
PMC5596242
AbstractArticlePDF–2.2M
9.
Blocking the 4-1BB Pathway Ameliorates Crystalline Silica-induced Lung Inflammation and Fibrosis in Mice
Chao Li, Sitong Du, Yiping Lu, Xiaowei Lu, Fangwei Liu, Ying Chen, Dong Weng, Jie Chen
Theranostics. 2016; 6(12): 2052–2067. Published online 2016 Sep 9. doi: 10.7150/thno.16180
PMCID:
PMC5039680
AbstractArticlePDF–3.0M
10.
4-1BB Signaling Enhances Primary and Secondary Population Expansion of CD8+ T Cells by Maximizing Autocrine IL-2/IL-2 Receptor Signaling
Ho S. Oh, Beom K. Choi, Young H. Kim, Don G. Lee, Sunhee Hwang, Myoung J. Lee, Sang H. Park, Yong-Soo Bae, Byoung S. Kwon
PLoS One. 2015; 10(5): e0126765. Published online 2015 May 11. doi: 10.1371/journal.pone.0126765
PMCID:
PMC4427336
AbstractArticlePDF–994K
11.
Regulation of Mouse 4-1BB Expression: Multiple Promoter Usages and a Splice Variant
Jung D. Kim, Chang H. Kim, Byoung S. Kwon
Mol Cells. 2011 Feb 28; 31(2): 141–149. doi: 10.1007/s10059-011-0018-6
PMCID:
PMC3932682
AbstractArticlePDF–850K
12.
Human and Mouse CD137 Have Predominantly Different Binding CRDs to Their Respective Ligands
Ling Yi, Yanlin Zhao, Xiaojue Wang, Min Dai, Karl Erik Hellström, Ingegerd Hellström, Hongtao Zhang
PLoS One. 2014; 9(1): e86337. Published online 2014 Jan 21. doi: 10.1371/journal.pone.0086337
PMCID:
PMC3897701
AbstractArticlePDF–1.0M
13.
Gene Targeting in NOD Mouse Embryos Using Zinc-Finger Nucleases
Yi-Guang Chen, Matthew H. Forsberg, Shamim Khaja, Ashley E. Ciecko, Martin J. Hessner, Aron M. Geurts
Diabetes. 2014 Jan; 63(1): 68–74. Published online 2013 Dec 13. doi: 10.2337/db13-0192
PMCID:
PMC3868049
AbstractArticlePDF–1.0M
14.
CD137 Facilitates the Resolution of Acute DSS-Induced Colonic Inflammation in Mice
Julia M. Martínez Gómez, Lieping Chen, Herbert Schwarz, Thomas Karrasch
PLoS One. 2013; 8(9): e73277. Published online 2013 Sep 4. doi: 10.1371/journal.pone.0073277
Correction in:
PLoS One. 2014; 9(1): 10.1371/annotation/83fd162d-b115-4af3-b6e7-dc23ae3f9a76.
PMCID:
PMC3762711
AbstractArticlePDF–2.4M
15.
CD137-Mediated Pathogenesis from Chronic Hepatitis to Hepatocellular Carcinoma in Hepatitis B Virus-Transgenic Mice
Jun Wang, Wenxia Zhao, Liang Cheng, Mingzhou Guo, Dongling Li, Xiaozhu Li, Yi Tan, Suping Ma, Suyun Li, Yunsheng Yang, Lieping Chen, Shengdian Wang
J Immunol. Author manuscript; available in PMC 2013 Mar 19.
Published in final edited form as: J Immunol. 2010 Dec 15; 185(12): 7654–7662. Published online 2010 Nov 8. doi: 10.4049/jimmunol.1000927
PMCID:
PMC3601909
AbstractArticlePDF–2.8M
16.
4-1BB Signaling Breaks the Tolerance of Maternal CD8+ T Cells That Are Reactive with Alloantigens
Kwang H. Kim, Beom K. Choi, Jung D. Kim, Young H. Kim, Sun K. Lee, Jae H. Suh, Sang C. Lee, Sang W. Kang, Byoung S. Kwon
PLoS One. 2012; 7(9): e45481. Published online 2012 Sep 21. doi: 10.1371/journal.pone.0045481
PMCID:
PMC3448654
AbstractArticlePDF–2.2M
17.
CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species
Yee Andy Yeo, Julia M Martínez Gómez, J Ludovic Croxford, Stephan Gasser, Eng-Ang Ling, Herbert Schwarz
J Neuroinflammation. 2012; 9: 173. Published online 2012 Jul 16. doi: 10.1186/1742-2094-9-173
PMCID:
PMC3420242
AbstractArticlePDF–3.5M
18.
CD137 deficiency does not affect development of airway inflammation or respiratory tolerance induction in murine models
A-K Behrendt, A Meyer-Bahlburg, G Hansen
Clin Exp Immunol. 2012 Jun; 168(3): 308–317. doi: 10.1111/j.1365-2249.2012.04572.x
PMCID:
PMC3390483
AbstractArticlePDF–678K
19.
The Tumor Necrosis Factor Receptor Subfamily 9 (Tnfrsf9) Gene is Expressed in Distinct Cell Populations in the Mouse Uterus and Conceptus During the Implantation Period of Pregnancy
Kirsten Eckstrum, Brent M. Bany
Cell Tissue Res. Author manuscript; available in PMC 2012 Jun 1.
Published in final edited form as: Cell Tissue Res. 2011 Jun; 344(3): 567–576. Published online 2011 May 12. doi: 10.1007/s00441-011-1171-0
PMCID:
PMC3104000
AbstractArticlePDF–2.7M
20.
Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells
Ian R Humphreys, Seung-Woo Lee, Morgan Jones, Andrea Loewendorf, Emma Gostick, David A Price, Chris A Benedict, Carl F Ware, Michael Croft
Eur J Immunol. 2010 Oct; 40(10): 2762–2768. doi: 10.1002/eji.200940256
PMCID:
PMC2967573
AbstractArticlePDF–296K

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