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Select item 83927181.

TWEAKing the Hippocampus: The Effects of TWEAK on the Genomic Fabric of the Hippocampus in a Neuropsychiatric Lupus Mouse Model

Dumitru A. Iacobas, Jing Wen, Sanda Iacobas, Chaim Putterman, Noa Schwartz

Genes (Basel) 2021 Aug; 12(8): 1172. Published online 2021 Jul 29. doi: 10.3390/genes12081172

PMCID:: PMC8392718

Abstract Article PDF–3.3M

Select item 67296922.

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

Ioana Potrovita, Wen Zhang, Linda Burkly, Kyungmin Hahm, John Lincecum, Monica Z. Wang, Martin H. Maurer, Moritz Rossner, Armin Schneider, Markus Schwaninger

J Neurosci. 2004 Sep 22; 24(38): 8237–8244. doi: 10.1523/JNEUROSCI.1089-04.2004

PMCID:: PMC6729692

Abstract Article PDF–448K

Select item 67257783.

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Increases the Permeability of the Neurovascular Unit through Nuclear Factor-κB Pathway Activation

Rohini Polavarapu, Maria Carolina Gongora, Jeffrey A. Winkles, Manuel Yepes

J Neurosci. 2005 Nov 2; 25(44): 10094–10100. doi: 10.1523/JNEUROSCI.3382-05.2005

PMCID:: PMC6725778

Abstract Article PDF–418K

Select item 49495304.

Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation

Annika Wilhelm, Emma L Shepherd, Aldo Amatucci, Mamoona Munir, Gary Reynolds, Elizabeth Humphreys, Yazid Resheq, David H Adams, Stefan Hübscher, Linda C Burkly, Christopher J Weston, Simon C Afford

J Pathol. 2016 May; 239(1): 109–121. Published online 2016 Mar 29. doi: 10.1002/path.4707

PMCID:: PMC4949530

Abstract Article PDF–5.3M

Select item 48191405.

Endogenous TWEAK is critical for regulating the function of mouse uterine natural killer cells in an immunological model of pregnancy loss

Xuefeng Qi, Mingzhu Lei, Lijuan Qin, Mengjie Xie, Dandan Zhao, Jingyu Wang

Immunology. 2016 May; 148(1): 70–82. Published online 2016 Mar 2. doi: 10.1111/imm.12588

PMCID:: PMC4819140

Abstract Article PDF–1.2M

Select item 47629466.

TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity

Ramesh S. Yadava, Erin P. Foff, Qing Yu, Jordan T. Gladman, Timothy S. Zheng, Mani S. Mahadevan

PLoS One. 2016; 11(2): e0150192. Published online 2016 Feb 22. doi: 10.1371/journal.pone.0150192

Correction in:: PLoS One. 2018; 13(2): e0192816.

PMCID:: PMC4762946

Abstract Article PDF–5.2M

Select item 45164897.

Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia

Ana B Sanz, Maria Dolores Sanchez-Niño, Maria Concepcion Izquierdo, Aniela Jakubowski, Pilar Justo, Luis M Blanco-Colio, Marta Ruiz-Ortega, Jesús Egido, Alberto Ortiz

J Cell Mol Med. 2009 Sep; 13(9b): 3329–3342. Published online 2009 May 1. doi: 10.1111/j.1582-4934.2009.00766.x

PMCID:: PMC4516489

Abstract Article PDF–1.6M

Select item 42835038.

Deletion of TNF-Like Weak Inducer of Apoptosis (TWEAK) Protects Mice From Adipose and Systemic Impacts of Severe Obesity

Grace Bennett, Katherine J. Strissel, Jason DeFuria, Junpeng Wang, Dayong Wu, Linda C. Burkly, Martin S. Obin

Obesity (Silver Spring) Author manuscript; available in PMC 2015 Jan 5.

Published in final edited form as: Obesity (Silver Spring). 2014 Jun; 22(6): 1485–1494. Published online 2014 Mar 8. doi: 10.1002/oby.20726

PMCID:: PMC4283503

Abstract Article PDF–1.0M

Select item 41543739.

Charu Dogra, Harish Changotra, Nia Wedhas, Xuezhong Qin, Jon E. Wergedal, Ashok Kumar

FASEB J. Author manuscript; available in PMC 2014 Sep 4.

Published in final edited form as: FASEB J. 2007 Jun; 21(8): 1857–1869. Published online 2007 Feb 21. doi: 10.1096/fj.06-7537com

PMCID:: PMC4154373

Abstract Article PDF–1.0M

Select item 415436910.

TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases

Shephali Bhatnagar, Ashwani Mittal, Sanjay K. Gupta, Ashok Kumar

J Cell Physiol. Author manuscript; available in PMC 2014 Sep 4.

Published in final edited form as: J Cell Physiol. 2012 Mar; 227(3): 1042–1051. doi: 10.1002/jcp.22821

PMCID:: PMC4154369

Abstract Article PDF–2.3M

Select item 382396411.

Exogenous Administration of a Recombinant Variant of TWEAK Impairs Healing after Myocardial Infarction by Aggravation of Inflammation

Christina Pachel, Denise Mathes, Barbara Bayer, Charlotte Dienesch, Gaby Wangorsch, Wolfram Heitzmann, Isabell Lang, Hossein Ardehali, Georg Ertl, Thomas Dandekar, Harald Wajant, Stefan Frantz

PLoS One. 2013; 8(11): e78938. Published online 2013 Nov 11. doi: 10.1371/journal.pone.0078938

PMCID:: PMC3823964

Abstract Article PDF–3.8M

Select item 294727012.

Genetic Ablation of TWEAK Augments Regeneration and Post-Injury Growth of Skeletal Muscle in Mice

Ashwani Mittal, Shephali Bhatnagar, Akhilesh Kumar, Pradyut K. Paul, Shihuan Kuang, Ashok Kumar

Am J Pathol. 2010 Oct; 177(4): 1732–1742. doi: 10.2353/ajpath.2010.100335

PMCID:: PMC2947270

Abstract Article PDF–830K

Select item 281329113.

TWEAK Activates the Non-Canonical NFκB Pathway in Murine Renal Tubular Cells: Modulation of CCL21

Ana B. Sanz, Maria D. Sanchez-Niño, Maria C. Izquierdo, Aniela Jakubowski, Pilar Justo, Luis M. Blanco-Colio, Marta Ruiz-Ortega, Rafael Selgas, Jesús Egido, Alberto Ortiz

PLoS One. 2010; 5(1): e8955. Published online 2010 Jan 29. doi: 10.1371/journal.pone.0008955

PMCID:: PMC2813291

Abstract Article PDF–4.2M

Select item 280824114.

Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice

Siva K. Panguluri, Shephali Bhatnagar, Akhilesh Kumar, John J. McCarthy, Apurva K. Srivastava, Nigel G. Cooper, Robert F. Lundy, Ashok Kumar

PLoS One. 2010; 5(1): e8760. Published online 2010 Jan 19. doi: 10.1371/journal.pone.0008760

PMCID:: PMC2808241

Abstract Article PDF–820K

Select item 954970615.

Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity

Gökhan Güner, Marlene Aßfalg, Kai Zhao, Tobias Dreyer, Shibojyoti Lahiri, Yun Lo, Bianca Ionela Slivinschi, Axel Imhof, Georg Jocher, Laura Strohm, Christian Behrends, Dieter Langosch, Holger Bronger, Christopher Nimsky, Jörg W Bartsch, Stanley R Riddell, Harald Steiner, Stefan F Lichtenthaler

EMBO Mol Med. 2022 Oct; 14(10): e16084. Published online 2022 Sep 7. doi: 10.15252/emmm.202216084

PMCID:: PMC9549706

Abstract Article PDF–1.5M

Select item 690466016.

Experimental atopic dermatitis is dependent on the TWEAK/Fn14 signaling pathway

Q. Liu, H. Wang, X. Wang, M. Lu, X. Tan, L. Peng, F. Tan, T. Xiao, S. Xiao, Y. Xia

Clin Exp Immunol. 2020 Jan; 199(1): 56–67. Published online 2019 Sep 17. doi: 10.1111/cei.13373

PMCID:: PMC6904660

Abstract Article PDF–1.4M

Select item 573321917.

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Activates Type I Interferon Signals in Lupus Nephritis

Leixi Xue, Lei Liu, Jun Huang, Jian Wen, Ru Yang, Lin Bo, Mei Tang, Yi Zhang, Zhichun Liu

Biomed Res Int. 2017; 2017: 4927376. Published online 2017 Nov 26. doi: 10.1155/2017/4927376

PMCID:: PMC5733219

Abstract Article PDF–2.0M

Select item 549359518.

TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis

Daniel Sidler, Ping Wu, Rana Herro, Meike Claus, Dennis Wolf, Yuko Kawakami, Toshiaki Kawakami, Linda Burkly, Michael Croft

Nat Commun. 2017; 8: 15395. Published online 2017 May 22. doi: 10.1038/ncomms15395

PMCID:: PMC5493595

Abstract Article PDF–1.9M

Select item 540683719.

TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice

Valvanera Fernández-Laso, Cristina Sastre, Nerea Méndez-Barbero, Jesús Egido, Jose L. Martín-Ventura, Carmen Gómez-Guerrero, Luis M. Blanco-Colio

Sci Rep. 2017; 7: 46679. Published online 2017 Apr 27. doi: 10.1038/srep46679

PMCID:: PMC5406837

Abstract Article PDF–2.7M

Select item 538539620.

Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice

Takuhito Sezaki, Yuki Hirata, Teruki Hagiwara, Yuki I Kawamura, Tadashi Okamura, Rieko Takanashi, Kenta Nakano, Miwa Tamura-Nakano, Linda C Burkly, Taeko Dohi

World J Gastroenterol. 2017 Apr 7; 23(13): 2294–2307. Published online 2017 Apr 7. doi: 10.3748/wjg.v23.i13.2294