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Select item 110084591.

FBXO11 regulates bone development

Hong Huang, Jianrong Lu, Ikramuddin Aukhil, Colton Yu, Brinda Bhut, Julie Marchesan, Flavia Pirih, Jia Chang

Bone. Author manuscript; available in PMC 2024 Apr 11.

Published in final edited form as: Bone. 2023 May; 170: 116709. Published online 2023 Mar 1. doi: 10.1016/j.bone.2023.116709

PMCID:: PMC11008459

Abstract Article PDF–1.6M

Select item 97099222.

FBXO11 inactivation leads to abnormal germinal-center formation and lymphoproliferative disease

Christof Schneider, Ning Kon, Letizia Amadori, Qiong Shen, Friederike H. Schwartz, Benjamin Tischler, Marion Bossennec, David Dominguez-Sola, Govind Bhagat, Wei Gu, Katia Basso, Riccardo Dalla-Favera

Blood. 2016 Aug 4; 128(5): 660–666. Published online 2020 Nov 24. doi: 10.1182/blood-2015-11-684357

Correction in:: Blood. 2023 Dec 14; 142(24): 2125.

PMCID:: PMC9709922

Abstract Article

Select item 72483983.

The Jeff Mouse Mutant Model for Chronic Otitis Media Manifests Gain-of-Function as Well as Loss-of-Function Effects

Oana Kubinyecz, Pratik P. Vikhe, Thomas Purnell, Steve D. M. Brown, Hilda Tateossian

Front Genet. 2020; 11: 498. Published online 2020 May 19. doi: 10.3389/fgene.2020.00498

PMCID:: PMC7248398

Abstract Article PDF–2.7M

Select item 70265034.

Mutation in Fbxo11 Leads to Altered Immune Cell Content in Jeff Mouse Model of Otitis Media

Pratik P. Vikhe, Hilda Tateossian, Gurpreet Bharj, Steve D.M. Brown, Derek W. Hood

Front Genet. 2020; 11: 50. Published online 2020 Feb 11. doi: 10.3389/fgene.2020.00050

PMCID:: PMC7026503

Abstract Article PDF–998K

Select item 62873505.

Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

Sofie Otzen Bagger, Branden Michael Hopkinson, Deo Prakash Pandey, Mads Bak, Andreas Vincent Brydholm, Rene Villadsen, Kristian Helin, Lone Rønnov-Jessen, Ole William Petersen, Jiyoung Kim

Mol Cancer. 2018; 17: 171. Published online 2018 Dec 10. doi: 10.1186/s12943-018-0918-6

PMCID:: PMC6287350

Abstract Article PDF–3.7M

Select item 32027146.

The Deaf Mouse Mutant Jeff (Jf) is a Single Gene Model of Otitis Media

Rachel E. Hardisty, Alexandra Erven, Karen Logan, Susan Morse, Sylvia Guionaud, Sara Sancho–Oliver, A. Jackie Hunter, Steve D. M. Brown, Karen P. Steel

J Assoc Res Otolaryngol. 2003 Jun; 4(2): 130–138. Published online 2002 Oct 31. doi: 10.1007/s10162-002-3015-9

PMCID:: PMC3202714

Summary PDF–562K

Select item 31976877.

HIF–VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants

Michael T. Cheeseman, Hayley E. Tyrer, Debbie Williams, Tertius A. Hough, Paras Pathak, Maria R. Romero, Helen Hilton, Sulzhan Bali, Andrew Parker, Lucie Vizor, Tom Purnell, Kate Vowell, Sara Wells, Mahmood F. Bhutta, Paul K. Potter, Steve D. M. Brown

PLoS Genet. 2011 Oct; 7(10): e1002336. Published online 2011 Oct 20. doi: 10.1371/journal.pgen.1002336

PMCID:: PMC3197687

Abstract Article PDF–594K

Select item 95556198.

Trans-cortical vessels in the mouse temporal bulla bone are a means to recruit myeloid cells in chronic otitis media and limit peripheral leukogram changes

Ali Azar, Mahmood F. Bhutta, Jorge Del-Pozo, Elspeth Milne, Michael Cheeseman

Front Genet. 2022; 13: 985214. Published online 2022 Sep 28. doi: 10.3389/fgene.2022.985214

PMCID:: PMC9555619

Abstract Article PDF–5.1M

Select item 89909269.

The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

Jorge del-Pozo, Denis J. Headon, James D. Glover, Ali Azar, Sonia Schuepbach-Mallepell, Mahmood F. Bhutta, Jon Riddell, Scott Maxwell, Elspeth Milne, Pascal Schneider, Michael Cheeseman

Dis Model Mech. 2022 Mar 1; 15(3): dmm049034. Published online 2022 Mar 30. doi: 10.1242/dmm.049034

PMCID:: PMC8990926

Abstract Article

Select item 668432410.

CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation

Chang Jiang, Stephen J. Trudeau, Taek-Chin Cheong, Rui Guo, Mingxiang Teng, Liang Wei Wang, Zhonghao Wang, Chiara Pighi, Carole Gautier-Courteille, Yijie Ma, Sizun Jiang, Chong Wang, Bo Zhao, Luc Paillard, John G. Doench, Roberto Chiarle, Benjamin E. Gewurz

Cell Rep. Author manuscript; available in PMC 2019 Aug 6.

Published in final edited form as: Cell Rep. 2019 Jul 30; 28(5): 1307–1322.e8. doi: 10.1016/j.celrep.2019.06.079

PMCID:: PMC6684324

Abstract Article PDF–2.9M

Select item 472833211.

A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse

Derek Hood, Richard Moxon, Tom Purnell, Caroline Richter, Debbie Williams, Ali Azar, Michael Crompton, Sara Wells, Martin Fray, Steve D. M. Brown, Michael T. Cheeseman

Dis Model Mech. 2016 Jan 1; 9(1): 69–79. doi: 10.1242/dmm.021659

PMCID:: PMC4728332

Abstract Article

Select item 36769412.

Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line.

A M Van der Bliek, T Van der Velde-Koerts, V Ling, P Borst

Mol Cell Biol. 1986 May; 6(5): 1671–1678. doi: 10.1128/mcb.6.5.1671

PMCID:: PMC367694

Summary Page Browse PDF–2.4M

Select item 915303713.

Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma

Chiara Pighi, Taek-Chin Cheong, Mara Compagno, Enrico Patrucco, Maddalena Arigoni, Martina Olivero, Qi Wang, Cristina López, Stephan H. Bernhart, Bruno M. Grande, Teresa Poggio, Fernanda Langellotto, Lisa Bonello, Riccardo Dall’Olio, Sandra Martínez-Martín, Luca Molinaro, Paola Francia di Celle, Jonathan R. Whitfield, Laura Soucek, Claudia Voena, Raffaele A. Calogero, Ryan D. Morin, Louis M. Staudt, Reiner Siebert, Alberto Zamò, Roberto Chiarle

Blood Adv. 2021 Dec 14; 5(23): 5239–5257. Published online 2021 Dec 8. doi: 10.1182/bloodadvances.2021005682

PMCID:: PMC9153037

Abstract Article PDF–3.2M

Select item 221337114.

Eya4-deficient mice are a model for heritable otitis media

Frederic F.S. Depreux, Keith Darrow, David A. Conner, Roland D. Eavey, M. Charles Liberman, Christine E. Seidman, J.G. Seidman

J Clin Invest. 2008 Feb 1; 118(2): 651–658. doi: 10.1172/JCI32899

PMCID:: PMC2213371

Abstract Article PDF–949K

Select item 334438515.

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas

Shanshan Duan, Lukas Cermak, Julia K. Pagan, Mario Rossi, Cinzia Martinengo, Paola Francia di Celle, Bjoern Chapuy, Margaret Shipp, Roberto Chiarle, Michele Pagano

Nature. Author manuscript; available in PMC 2012 Jul 5.

Published in final edited form as: Nature. 2012 Jan 5; 481(7379): 90–93. doi: 10.1038/nature10688

PMCID:: PMC3344385

Abstract Article PDF–1.2M

Select item 334107516.

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

Karen M. Mann, Jerrold M. Ward, Christopher Chin Kuan Yew, Anne Kovochich, David W. Dawson, Michael A. Black, Benjamin T. Brett, Todd E. Sheetz, Adam J. Dupuy, Australian Pancreatic Cancer Genome Initiative, David K. Chang, Andrew V. Biankin, Nicola Waddell, Karin S. Kassahn, Sean M. Grimmond, Alistair G. Rust, David J. Adams, Nancy A. Jenkins, Neal G. Copeland

Proc Natl Acad Sci U S A. 2012 Apr 17; 109(16): 5934–5941. Published online 2012 Mar 15. doi: 10.1073/pnas.1202490109

PMCID:: PMC3341075

Abstract Article PDF–1.3M

Select item 1026827417.

FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA

Yusuke Kasuga, Ryota Ouda, Masashi Watanabe, Xin Sun, Miki Kimura, Shigetsugu Hatakeyama, Koichi S. Kobayashi

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2218955120. Published online 2023 Jun 6. doi: 10.1073/pnas.2218955120

PMCID:: PMC10268274

Abstract Article PDF–2.3M

Select item 440648818.

FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development

Yue Jin, Anitha K. Shenoy, Samuel Doernberg, Hao Chen, Huacheng Luo, Huangxuan Shen, Tong Lin, Miriam Tarrash, Qingsong Cai, Xin Hu, Ryan Fiske, Ting Chen, Lizi Wu, Kamal A. Mohammed, Veerle Rottiers, Siu Sylvia Lee, Jianrong Lu

Cancer Lett. Author manuscript; available in PMC 2016 Jun 28.

Published in final edited form as: Cancer Lett. 2015 Jun 28; 362(1): 70–82. Published online 2015 Mar 28. doi: 10.1016/j.canlet.2015.03.037

PMCID:: PMC4406488

Abstract Article PDF–1.6M

Select item 271448319.

Regulation of TGF-β signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

Hilda Tateossian, Rachel E Hardisty-Hughes, Susan Morse, Maria R Romero, Helen Hilton, Charlotte Dean, Steve DM Brown

Pathogenetics. 2009; 2: 5. Published online 2009 Jul 6. doi: 10.1186/1755-8417-2-5

PMCID:: PMC2714483

Abstract Article PDF–2.1M

Select item 472832220.

Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung

Hilda Tateossian, Susan Morse, Michelle M. Simon, Charlotte H. Dean, Steve D. M. Brown

Dis Model Mech. 2015 Dec 1; 8(12): 1531–1542. doi: 10.1242/dmm.022426

PMCID:: PMC4728322

Abstract Article

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