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Select item 90044451.

Photorepair of Either CPD or 6-4PP DNA Lesions in Basal Keratinocytes Attenuates Ultraviolet-Induced Skin Effects in Nucleotide Excision Repair Deficient Mice

Gustavo S. Kajitani, Carolina Quayle, Camila C. M. Garcia, Wesley L. Fotoran, Juliana F. R. dos Santos, Gijsbertus T. J. van der Horst, Jan H. J. Hoeijmakers, Carlos F. M. Menck

Front Immunol. 2022; 13: 800606. Published online 2022 Mar 29. doi: 10.3389/fimmu.2022.800606

PMCID:: PMC9004445

Abstract Article PDF–2.2M

Select item 53010832.

Hearing Dysfunction in Xpa-Deficient Mice

Hitomi Shinomiya, Daisuke Yamashita, Takeshi Fujita, Eiji Nakano, Go Inokuchi, Shingo Hasegawa, Naoki Otsuki, Chikako Nishigori, Ken-ichi Nibu

Front Aging Neurosci. 2017; 9: 19. Published online 2017 Feb 10. doi: 10.3389/fnagi.2017.00019

PMCID:: PMC5301083

Abstract Article PDF–1.0M

Select item 45514803.

Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice

Hironobu Nakane, Seiichi Hirota, Philip J. Brooks, Yusaku Nakabeppu, Yoshimichi Nakatsu, Yoshitake Nishimune, Akihiro Iino, Kiyoji Tanaka

DNA Repair (Amst) Author manuscript; available in PMC 2015 Aug 27.

Published in final edited form as: DNA Repair (Amst). 2008 Dec 1; 7(12): 1938–1950. Published online 2008 Oct 1. doi: 10.1016/j.dnarep.2008.08.003

PMCID:: PMC4551480

Abstract Article PDF–1.5M

Select item 36041664.

Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cells

Mudit Vaid, Ram Prasad, Tripti Singh, Craig A. Elmets, Hui Xu, Santosh K. Katiyar

Biochem Pharmacol. Author manuscript; available in PMC 2014 Apr 15.

Published in final edited form as: Biochem Pharmacol. 2013 Apr 15; 85(8): 1066–1076. Published online 2013 Feb 5. doi: 10.1016/j.bcp.2013.01.026

PMCID:: PMC3604166

Abstract Article PDF–2.6M

Select item 34990455.

Benzo[a]pyrene (BP) DNA adduct formation in DNA repair–deficient p53 haploinsufficient [Xpa(−/−)p53(+/−)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days

Kaarthik John, M.Margaret Pratt, Frederick A. Beland, Mona I. Churchwell, Gail McMullen, Ofelia A. Olivero, Igor P. Pogribny, Miriam C. Poirier

Carcinogenesis. 2012 Nov; 33(11): 2236–2241. Published online 2012 Jul 14. doi: 10.1093/carcin/bgs247

PMCID:: PMC3499045

Abstract Article PDF–455K

Select item 33088146.

Platelet-activating Factor Receptor Agonists Mediate Xeroderma Pigmentosum A Photosensitivity

Yongxue Yao, Kathleen A. Harrison, Mohammed Al-Hassani, Robert C. Murphy, Samin Rezania, Raymond L. Konger, Jeffrey B. Travers

J Biol Chem. 2012 Mar 16; 287(12): 9311–9321. Published online 2012 Feb 1. doi: 10.1074/jbc.M111.332395

PMCID:: PMC3308814

Abstract Article PDF–1.2M

Select item 28553967.

Agents that reverse UV-induced immune suppression and photocarcinogenesis affect DNA repair

Coimbatore S. Sreevidya, Atsushi Fukunaga, Noor M. Khaskhely, Taro Masaki, Ryusuke Ono, Chikako Nishigori, Stephen E. Ullrich

J Invest Dermatol. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: J Invest Dermatol. 2010 May; 130(5): 1428–1437. Published online 2009 Oct 15. doi: 10.1038/jid.2009.329

PMCID:: PMC2855396

Abstract Article PDF–2.7M

Select item 22127838.

Prevention of UV radiation–induced immunosuppression by IL-12 is dependent on DNA repair

Agatha Schwarz, Akira Maeda, Kerstin Kernebeck, Harry van Steeg, Stefan Beissert, Thomas Schwarz

J Exp Med. 2005 Jan 17; 201(2): 173–179. doi: 10.1084/jem.20041212

PMCID:: PMC2212783

Abstract Article PDF–332K

Select item 3077389.

Cloning and characterization of the mouse XPAC gene.

C T van Oostrom, A de Vries, S J Verbeek, C F van Kreijl, H van Steeg

Nucleic Acids Res. 1994 Jan 11; 22(1): 11–14. doi: 10.1093/nar/22.1.11

PMCID:: PMC307738

Summary Page Browse PDF–789K

Select item 29765310.

Molecular cloning of a mouse DNA repair gene that complements the defect of group-A xeroderma pigmentosum.

K Tanaka, I Satokata, Z Ogita, T Uchida, Y Okada

Proc Natl Acad Sci U S A. 1989 Jul; 86(14): 5512–5516. doi: 10.1073/pnas.86.14.5512

PMCID:: PMC297653

Summary Page Browse PDF–1.0M

Select item 854430611.

Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model

Gustavo Satoru Kajitani, Lear Brace, Jose Humberto Trevino-Villarreal, Kaspar Trocha, Michael Robert MacArthur, Sarah Vose, Dorathy Vargas, Roderick Bronson, Sarah Jayne Mitchell, Carlos Frederico Martins Menck, James Robert Mitchell

Aging (Albany NY) 2021 Oct 15; 13(19): 22710–22731. Published online 2021 Oct 10. doi: 10.18632/aging.203617

PMCID:: PMC8544306

Abstract Article PDF–1.7M

Select item 696112812.

Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts

Lisa Hölzl-Armstrong, Jill E. Kucab, Michael Korenjak, Mirjam Luijten, David H. Phillips, Jiri Zavadil, Volker M. Arlt

Methods Protoc. 2019 Dec; 2(4): 85. Published online 2019 Nov 13. doi: 10.3390/mps2040085

PMCID:: PMC6961128

Abstract Article PDF–16M

Select item 479884813.

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

Jill E. Kucab, Edwin P. Zwart, Harry van Steeg, Mirjam Luijten, Heinz H. Schmeiser, David H. Phillips, Volker M. Arlt

DNA Repair (Amst) 2016 Mar; 39: 21–33. doi: 10.1016/j.dnarep.2015.11.004

PMCID:: PMC4798848

Abstract Article PDF–1.4M

Select item 379943714.

XPD-dependent activation of apoptosis in response to triplex-induced DNA damage

Meetu Kaushik Tiwari, Faye A. Rogers

Nucleic Acids Res. 2013 Oct; 41(19): 8979–8994. Published online 2013 Aug 2. doi: 10.1093/nar/gkt670

PMCID:: PMC3799437

Abstract Article PDF–17M

Select item 342454415.

Endogenous formation and repair of oxidatively induced G[8-5 m]T intrastrand cross-link lesion

Jin Wang, Huachuan Cao, Changjun You, Bifeng Yuan, Ralf Bahde, Sanjeev Gupta, Chikako Nishigori, Laura J. Niedernhofer, Philip J. Brooks, Yinsheng Wang

Nucleic Acids Res. 2012 Aug; 40(15): 7368–7374. Published online 2012 May 11. doi: 10.1093/nar/gks357

PMCID:: PMC3424544

Abstract Article PDF–403K

Select item 322153416.

Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1

Leroy Hubert, Jr, Yunfu Lin, Vincent Dion, John H. Wilson

Hum Mol Genet. 2011 Dec 15; 20(24): 4822–4830. Published online 2011 Sep 15. doi: 10.1093/hmg/ddr421

PMCID:: PMC3221534

Abstract Article PDF–230K

Select item 189242617.

p53 Haploinsufficiency Profoundly Accelerates the Onset of Tongue Tumors in Mice Lacking the Xeroderma Pigmentosum Group A Gene

Fumio Ide, Munenori Kitada, Hideaki Sakashita, Kaoru Kusama, Kiyoji Tanaka, Takatoshi Ishikawa

Am J Pathol. 2003 Nov; 163(5): 1729–1733. doi: 10.1016/S0002-9440(10)63531-6

PMCID:: PMC1892426

Abstract Article PDF–334K

Select item 6087918.

Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne Syndrome Group B DNA repair genes

Machiko Murai, Yasushi Enokido, Naoko Inamura, Masafumi Yoshino, Yoshimichi Nakatsu, Gijsbertus T. J. van der Horst, Jan H. J. Hoeijmakers, Kiyoji Tanaka, Hiroshi Hatanaka

Proc Natl Acad Sci U S A. 2001 Nov 6; 98(23): 13379–13384. Published online 2001 Oct 30. doi: 10.1073/pnas.231329598

PMCID:: PMC60879

Abstract Article PDF–591K

Select item 913083519.

Genome Replication Is Associated With Release of Immunogenic DNA Waste

Nadja Schubert, Tina Schumann, Elena Daum, Karolin Flade, Yan Ge, Lara Hagedorn, Winfried Edelmann, Luise Müller, Marc Schmitz, Gunnar Kuut, Veit Hornung, Rayk Behrendt, Axel Roers

Front Immunol. 2022; 13: 880413. Published online 2022 May 11. doi: 10.3389/fimmu.2022.880413

PMCID:: PMC9130835

Abstract Article PDF–6.8M

Select item 462583720.

Defective Mitophagy in XPA via PARP1 Hyperactivation and NAD+/SIRT1 Reduction

Evandro Fei Fang, Morten Scheibye-Knudsen, Lear E. Brace, Henok Kassahun, Tanima SenGupta, Hilde Nilsen, James R. Mitchell, Deborah L. Croteau, Vilhelm A. Bohr

Cell. Author manuscript; available in PMC 2015 Oct 29.

Published in final edited form as: Cell. 2014 May 8; 157(4): 882–896. doi: 10.1016/j.cell.2014.03.026