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Items: 1 to 20 of 314

1.
Expression of fibroblast growth factor receptor 2 (FGFR2) in combined hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma: clinicopathological study
Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma
Virchows Arch. 2024; 484(6): 915–923. Published online 2024 Mar 27. doi: 10.1007/s00428-024-03792-x
PMCID:
PMC11186861
AbstractArticlePDF–1.3M
2.
Elucidating the Role of Wildtype and Variant FGFR2 Structural Dynamics in (Dys)Function and Disorder
Yiyang Lian, Dale Bodian, Amarda Shehu
Int J Mol Sci. 2024 Apr; 25(8): 4523. Published online 2024 Apr 20. doi: 10.3390/ijms25084523
PMCID:
PMC11050683
AbstractArticlePDF–19M
3.
Genetic insights into the ‘sandwich fusion’ subtype of Klippel–Feil syndrome: novel FGFR2 mutations identified by 21 cases of whole-exome sequencing
Nanfang Xu, Kan-Lin Hung, Xiaoli Gong, Dongwei Fan, Yinglun Tian, Ming Yan, Yuan Wei, Shenglin Wang
Orphanet J Rare Dis. 2024; 19: 141. Published online 2024 Apr 1. doi: 10.1186/s13023-024-03134-9
PMCID:
PMC10985996
AbstractArticlePDF–1.5M
4.
Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes
Julia Schmidt, Silke Kaulfuß, Hagen Ott, Marianne Gaubert, Nadine Reintjes, Felix Bremmer, Steffi Dreha-Kulaczewski, Philipp Stroebel, Gökhan Yigit, Bernd Wollnik
Hum Genet. 2024; 143(2): 159–168. Published online 2024 Jan 24. doi: 10.1007/s00439-023-02634-1
PMCID:
PMC10881730
AbstractArticlePDF–2.5M
5.
FGFR2 genetic variants in women with breast cancer
Thérèse Dix-Peek, Caroline Dickens, Tanya N. Augustine, Boitumelo P. Phakathi, Eunice J. Van Den Berg, Maureen Joffe, Oluwatosin A. Ayeni, Herbert Cubasch, Sarah Nietz, Christopher G. Mathew, Mahtaab Hayat, Alfred I. Neugut, Judith S. Jacobson, Paul Ruff, Raquel A.B. Duarte
Mol Med Rep. 2023 Dec; 28(6): 226. Published online 2023 Oct 10. doi: 10.3892/mmr.2023.13113
PMCID:
PMC10619128
AbstractArticlePDF–375K
6.
Functional Distinctions of Endometrial Cancer-Associated Mutations in the Fibroblast Growth Factor Receptor 2 Gene
Garima Dixit, Benjamin A. Pappas, Gourav Bhardwaj, Willow Schanz, Thorsten Maretzky
Cells. 2023 Sep; 12(18): 2227. Published online 2023 Sep 7. doi: 10.3390/cells12182227
PMCID:
PMC10526318
AbstractArticlePDF–2.0M
7.
FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways
Garima Dixit, Jesus Gonzalez‐Bosquet, Joseph Skurski, Eric J. Devor, Erin B. Dickerson, Warren B. Nothnick, Priya D. Issuree, Kimberly K. Leslie, Thorsten Maretzky
Clin Transl Med. 2023 May; 13(5): e1223. Published online 2023 May 10. doi: 10.1002/ctm2.1223
PMCID:
PMC10172618
AbstractArticlePDF–8.4M
8.
Effect of FGFR2 Alterations on Overall and Progression-Free Survival in Patients Receiving Systemic Therapy for Intrahepatic Cholangiocarcinoma
Ghassan K. Abou-Alfa, Kristen Bibeau, Nikolaus Schultz, Amin Yaqubie, Brittanie Millang, Haobo Ren, Luis Féliz
Target Oncol. 2022; 17(5): 517–527. Published online 2022 Sep 17. doi: 10.1007/s11523-022-00906-w
PMCID:
PMC9512879
AbstractArticlePDF–855K
9.
Circulating Tumor DNA Analysis Detects FGFR2 Amplification and Concurrent Genomic Alterations Associated with FGFR Inhibitor Efficacy in Advanced Gastric Cancer
Tomoko Jogo, Yoshiaki Nakamura, Kohei Shitara, Hideaki Bando, Hisateru Yasui, Taito Esaki, Tetsuji Terazawa, Taroh Satoh, Eiji Shinozaki, Tomohiro Nishina, Yu Sunakawa, Yoshito Komatsu, Hiroki Hara, Eiji Oki, Nobuhisa Matsuhashi, Takashi Ohta, Takeshi Kato, Koushiro Ohtsubo, Takeshi Kawakami, Naohiro Okano, Yoshiyuki Yamamoto, Takanobu Yamada, Akihito Tsuji, Justin I. Odegaard, Hiroya Taniguchi, Toshihiko Doi, Satoshi Fujii, Takayuki Yoshino
Clin Cancer Res. 2021 Oct 15; 27(20): 5619–5627. Published online 2021 Aug 10. doi: 10.1158/1078-0432.CCR-21-1414
PMCID:
PMC9401460
AbstractArticlePDF–881K
10.
成纤维细胞生长因子受体2在肾透明细胞癌中的表达及意义
蔡 天玉, 朱 振鹏, 徐 纯如, 吉 星, 吕 同德, 郭 振可, 林 健
Beijing Da Xue Xue Bao Yi Xue Ban. 2022 Aug 18; 54(4): 628–635. Chinese. Published online 2022 Jun 20. doi: 10.19723/j.issn.1671-167X.2022.04.008
PMCID:
PMC9385531
AbstractArticlePDF–5.2M
11.
Mother and Daughter Carrying of the Same Pathogenic Variant in FGFR2 with Discordant Phenotype
Filomena Lo Vecchio, Elisabetta Tabolacci, Veronica Nobile, Maria Grazia Pomponi, Roberta Pietrobono, Giovanni Neri, Simona Amenta, Ettore Candida, Cristina Grippaudo, Ettore Lo Cascio, Alessia Vita, Federica Tiberio, Alessandro Arcovito, Wanda Lattanzi, Maurizio Genuardi, Pietro Chiurazzi
Genes (Basel) 2022 Jul; 13(7): 1161. Published online 2022 Jun 27. doi: 10.3390/genes13071161
PMCID:
PMC9319849
AbstractArticlePDF–2.1M
12.
FGFR2 accommodates osteogenic cell fate determination in human mesenchymal stem cells
Ying Zhang, Ling Ling, Arya Ajay D/O Ajayakumar, Yating Michelle Eio, Andre J. van Wijnen, Victor Nurcombe, Simon M. Cool
Gene. Author manuscript; available in PMC 2023 Apr 15.
Published in final edited form as: Gene. 2022 Apr 15; 818: 146199. Published online 2022 Jan 29. doi: 10.1016/j.gene.2022.146199
PMCID:
PMC9256080
AbstractArticlePDF–2.0M
13.
Fibroblast growth factor receptor 2 promotes the proliferation, migration, and invasion of ectopic stromal cells via activation of extracellular-signal-regulated kinase signaling pathway in endometriosis
Yuan Xu, Feng Gao, Jingyong Zhang, Pingping Cai, Dongsheng Xu
Bioengineered. 2022; 13(4): 8360–8371. Published online 2022 Mar 21. doi: 10.1080/21655979.2022.2054207
PMCID:
PMC9161834
AbstractArticlePDF–2.8M
14.
Genomic Understanding Reveals the Important Role of FGFR2 as Paeoniflorin Target for Circumventing Breast Cancer Resistance to Tamoxifen
Moh Arikus Wibowo, Eri Prasetyo Nugroho, Adam Hermawan
Asian Pac J Cancer Prev. 2021 Dec; 22(12): 3949–3958. doi: 10.31557/APJCP.2021.22.12.3949
PMCID:
PMC9080378
AbstractArticlePDF–1.5M
15.
Phenotypic variability of syndromic craniosynostosis caused by c.833G > T in FGFR2: Clinical and genetic evaluation of eight patients from a five‐generation family
Xianda Wei, Guori Huang, Baoheng Gui, Bobo Xie, Shaoke Chen, Xin Fan, Yujun Chen
Mol Genet Genomic Med. 2022 Apr; 10(4): e1901. Published online 2022 Mar 2. doi: 10.1002/mgg3.1901
PMCID:
PMC9000941
AbstractArticlePDF–1.2M
16.
FGFR2 overexpression and compromised survival in diffuse-type gastric cancer in a large central European cohort
Thorben Schrumpf, Hans-Michael Behrens, Jochen Haag, Sandra Krüger, Christoph Röcken
PLoS One. 2022; 17(2): e0264011. Published online 2022 Feb 15. doi: 10.1371/journal.pone.0264011
PMCID:
PMC8846517
AbstractArticlePDF–3.0M
17.
FGFR2 loss sensitizes MYCN‐amplified neuroblastoma CHP134 cells to CHK1 inhibitor–induced apoptosis
Kiyohiro Ando, Miki Ohira, Ichiro Takada, Verna Cázares‐Ordoñez, Yusuke Suenaga, Hiroki Nagase, Shinichi Kobayashi, Tsugumichi Koshinaga, Takehiko Kamijo, Makoto Makishima, Satoshi Wada
Cancer Sci. 2022 Feb; 113(2): 587–596. Published online 2021 Nov 30. doi: 10.1111/cas.15205
PMCID:
PMC8819351
AbstractArticlePDF–1.0M
18.
Cancer-related FGFR2 overexpression and gene amplification in Japanese patients with gastric cancer
Keiko Minashi, Takeshi Yamada, Hisashi Hosaka, Kenji Amagai, Yoshiaki Shimizu, Hirokazu Kiyozaki, Mikio Sato, Atsuko Soeda, Shinji Endo, Hiroyasu Ishida, Toshiro Kamoshida, Yoshinori Sakai, Kohei Shitara
Jpn J Clin Oncol. 2021 Oct; 51(10): 1523–1533. Published online 2021 Jul 13. doi: 10.1093/jjco/hyab104
PMCID:
PMC8491535
AbstractArticlePDF–790K
19.
Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study
Prof Ghassan K Abou-Alfa, Vaibhav Sahai, Antoine Hollebecque, Gina Vaccaro, Davide Melisi, Raed Al-Rajabi, Andrew S Paulson, Mitesh J Borad, David Gallinson, Adrian G Murphy, Prof Do-Youn Oh, Efrat Dotan, Daniel V Catenacci, Prof Eric Van Cutsem, Tao Ji, Christine F Lihou, Huiling Zhen, Luis Féliz, Prof Arndt Vogel
Lancet Oncol. Author manuscript; available in PMC 2021 Sep 24.
Published in final edited form as: Lancet Oncol. 2020 May; 21(5): 671–684. Published online 2020 Mar 20. doi: 10.1016/S1470-2045(20)30109-1
PMCID:
PMC8461541
AbstractArticlePDF–1.5M
20.
FGFR2 alteration as a potential therapeutic target in poorly cohesive gastric carcinoma
Yue Wang, Tao Shi, Xuan Wang, Jinwei Hu, Lixia Yu, Qin Liu, Nandie Wu, Baorui Liu, Jia Wei
J Transl Med. 2021; 19: 401. Published online 2021 Sep 22. doi: 10.1186/s12967-021-03079-8
PMCID:
PMC8459493
AbstractArticlePDF–2.5M

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