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Select item 73134801.

Beneficial impact of Baricitinib in COVID-19 moderate pneumonia; multicentre study

Fabrizio Cantini, Laura Niccoli, Carlotta Nannini, Daniela Matarrese, Massimo Edoardo Di Natale, Pamela Lotti, Donatella Aquilini, Giancarlo Landini, Barbara Cimolato, Massimo Antonio Di Pietro, Michele Trezzi, Paolo Stobbione, Gabriele Frausini, Assunta Navarra, Emanuele Nicastri, Giovanni Sotgiu, Delia Goletti

J Infect. 2020 Oct; 81(4): 647–679. Published online 2020 Jun 24. doi: 10.1016/j.jinf.2020.06.052

PMCID:: PMC7313480

Abstract Article PDF–5.3M

Select item 71770732.

Baricitinib therapy in COVID-19: A pilot study on safety and clinical impact

Fabrizio Cantini, Laura Niccoli, Daniela Matarrese, Emanuele Nicastri, Paolo Stobbione, Delia Goletti

J Infect. 2020 Aug; 81(2): 318–356. Published online 2020 Apr 23. doi: 10.1016/j.jinf.2020.04.017

PMCID:: PMC7177073

Abstract Article PDF–7.3M

Select item 71379853.

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease

Peter Richardson, Ivan Griffin, Catherine Tucker, Dan Smith, Olly Oechsle, Anne Phelan, Michael Rawling, Edward Savory, Justin Stebbing

Lancet. 2020 15-21 February; 395(10223): e30–e31. Published online 2020 Feb 4. doi: 10.1016/S0140-6736(20)30304-4

Correction in:: Lancet. 2020 20-26 June; 395(10241): 1906.

PMCID:: PMC7137985

Article PDF–218K

Select item 70858624.

Potential Treatments for COVID-19; a Narrative Literature Review

Ali Rismanbaf

Arch Acad Emerg Med. 2020; 8(1): e29. Published online 2020 Mar 21.

PMCID:: PMC7085862

Abstract Article PDF–305K

Select item 70744325.

Therapeutic options for the treatment of 2019-novel coronavirus: An evidence-based approach

Phulen Sarma, Manisha Prajapat, Pramod Avti, Hardeep Kaur, Subodh Kumar, Bikash Medhi

Indian J Pharmacol. 2020 Jan-Feb; 52(1): 1–5. Published online 2020 Mar 11. doi: 10.4103/ijp.IJP_119_20

PMCID:: PMC7074432

Article

Select item 70195866.

The Serine/Threonine Kinase AP2-Associated Kinase 1 Plays an Important Role in Rabies Virus Entry

Chong Wang, Jinliang Wang, Lei Shuai, Xiao Ma, Hailin Zhang, Renqiang Liu, Weiye Chen, Xijun Wang, Jinying Ge, Zhiyuan Wen, Zhigao Bu

Viruses. 2020 Jan; 12(1): 45. Published online 2019 Dec 30. doi: 10.3390/v12010045

PMCID:: PMC7019586

Abstract Article PDF–4.9M

Select item 26586907.

Unlocking the Mysteries of Na⁺-K⁺-ATPase Endocytosis: Phosphorylation Is the Key

James F. Collawn

Am J Respir Cell Mol Biol. 2006 Jul; 35(1): 1–2. doi: 10.1165/rcmb.f317

PMCID:: PMC2658690

Article PDF–56K

Select item 21728168.

Differential requirements for AP-2 in clathrin-mediated endocytosis

Sean D. Conner, Sandra L. Schmid

J Cell Biol. 2003 Sep 1; 162(5): 773–780. doi: 10.1083/jcb.200304069

PMCID:: PMC2172816

Abstract Article PDF–278K

Select item 71459369.

Rheumatologists’ perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets

Durga Prasanna Misra, Vikas Agarwal, Armen Yuri Gasparyan, Olena Zimba

Clin Rheumatol. 2020; 39(7): 2055–2062. Published online 2020 Apr 10. doi: 10.1007/s10067-020-05073-9

PMCID:: PMC7145936

Abstract Article PDF–625K

Select item 631537610.

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

Megan J. Agajanian, Matthew P. Walker, Alison D. Axtman, Roberta R. Ruela-de-Sousa, D. Stephen Serafin, Alex D. Rabinowitz, David M. Graham, Meagan B. Ryan, Tigist Tamir, Yuko Nakamichi, Melissa V. Gammons, James M. Bennett, Rafael M. Couñago, David H. Drewry, Jonathan M. Elkins, Carina Gileadi, Opher Gileadi, Paulo H. Godoi, Nirav Kapadia, Susanne Müller, André S. Santiago, Fiona J. Sorrell, Carrow I. Wells, Oleg Fedorov, Timothy M. Willson, William J. Zuercher, Michael B. Major

Cell Rep. 2019 Jan 2; 26(1): 79–93.e8. Published online 2019 Jan 2. doi: 10.1016/j.celrep.2018.12.023

PMCID:: PMC6315376

Abstract Article PDF–3.5M

Select item 478086411.

Family-wide Structural Analysis of Human Numb-Associated Protein Kinases

Fiona J. Sorrell, Marta Szklarz, Kamal R. Abdul Azeez, Jon M. Elkins, Stefan Knapp

Structure. 2016 Mar 1; 24(3): 401–411. doi: 10.1016/j.str.2015.12.015

PMCID:: PMC4780864

Abstract Article PDF–3.2M

Select item 444239512.

AP-2-Associated Protein Kinase 1 and Cyclin G-Associated Kinase Regulate Hepatitis C Virus Entry and Are Potential Drug Targets

Gregory Neveu, Amotz Ziv-Av, Rina Barouch-Bentov, Elena Berkerman, Jon Mulholland, Shirit Einav

J Virol. 2015 Apr 15; 89(8): 4387–4404. Published online 2015 Feb 4. doi: 10.1128/JVI.02705-14

PMCID:: PMC4442395

Abstract Article PDF–3.2M

Select item 309968913.

The Adaptor-associated Kinase 1, AAK1, Is a Positive Regulator of the Notch Pathway

Neetu Gupta-Rossi, Sara Ortica, Vannary Meas-Yedid, Sara Heuss, Julien Moretti, Jean-Christophe Olivo-Marin, Alain Israël

J Biol Chem. 2011 May 27; 286(21): 18720–18730. Published online 2011 Apr 4. doi: 10.1074/jbc.M110.190769

PMCID:: PMC3099689

Abstract Article PDF–3.3M

Select item 217330414.

Phosphorylation of the AP2 μ subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

Doris Ricotta, Sean D. Conner, Sandra L. Schmid, Kurt von Figura, Stefan Höning

J Cell Biol. 2002 Mar 4; 156(5): 791–795. doi: 10.1083/jcb.200111068

PMCID:: PMC2173304

Abstract Article PDF–150K

Select item 192482015.

A Novel AAK1 Splice Variant Functions at Multiple Steps of the Endocytic Pathway

Davin M. Henderson, Sean D. Conner

Mol Biol Cell. 2007 Jul; 18(7): 2698–2706. doi: 10.1091/mbc.E06-09-0831

PMCID:: PMC1924820

Abstract Article PDF–912K

Select item 1018864016.

Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis

Jie Lian, Xinxing Zhu, Jiang Du, Beijia Huang, Fengting Zhao, Chunya Ma, Rui Guo, Yangxia Zhang, Longkai Ji, Badrul Hisham Yahaya, Juntang Lin

Mol Ther. 2023 May 3; 31(5): 1365–1382. Published online 2023 Feb 2. doi: 10.1016/j.ymthe.2023.01.025

PMCID:: PMC10188640

Abstract Article PDF–5.8M

Select item 217331717.

Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis

Sean D. Conner, Sandra L. Schmid

J Cell Biol. 2002 Mar 4; 156(5): 921–929. doi: 10.1083/jcb.200108123

PMCID:: PMC2173317

Abstract Article PDF–508K

Select item 275886618.

Genomewide association study for onset age in Parkinson disease

Jeanne C Latourelle, Nathan Pankratz, Alexandra Dumitriu, Jemma B Wilk, Stefano Goldwurm, Gianni Pezzoli, Claudio B Mariani, Anita L DeStefano, Cheryl Halter, James F Gusella, William C Nichols, Richard H Myers, Tatiana Foroud, the PSG -PROGENI and GenePD Investigators, Coordinators and Molecular Genetic Laboratories

BMC Med Genet. 2009; 10: 98. Published online 2009 Sep 22. doi: 10.1186/1471-2350-10-98

PMCID:: PMC2758866

Abstract Article PDF–521K

Select item 424987119.

Genetic Variants Associated with Serum Thyroid Stimulating Hormone (TSH) Levels in European Americans and African Americans from the eMERGE Network

Jennifer R. Malinowski, Joshua C. Denny, Suzette J. Bielinski, Melissa A. Basford, Yuki Bradford, Peggy L. Peissig, David Carrell, David R. Crosslin, Jyotishman Pathak, Luke Rasmussen, Jennifer Pacheco, Abel Kho, Katherine M. Newton, Rongling Li, Iftikhar J. Kullo, Christopher G. Chute, Rex L. Chisholm, Gail P. Jarvik, Eric B. Larson, Catherine A. McCarty, Daniel R. Masys, Dan M. Roden, Mariza de Andrade, Marylyn D. Ritchie, Dana C. Crawford

PLoS One. 2014; 9(12): e111301. Published online 2014 Dec 1. doi: 10.1371/journal.pone.0111301

PMCID:: PMC4249871

Abstract Article PDF–941K

Select item 154070620.

Role of the AP2 β-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly

Eva M Schmid, Marijn G. J Ford, Anne Burtey, Gerrit J. K Praefcke, Sew-Yeu Peak-Chew, Ian G Mills, Alexandre Benmerah, Harvey T McMahon

PLoS Biol. 2006 Sep; 4(9): e262. Published online 2006 Aug 15. doi: 10.1371/journal.pbio.0040262

PMCID:: PMC1540706

Abstract Article PDF–2.9M

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