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Select item 109680531.

Increased NLRP1 mRNA and Protein Expression Suggests Inflammasome Activation in the Dorsolateral Prefrontal and Medial Orbitofrontal Cortex in Schizophrenia

Ena Španić Popovački, Dora Vogrinc, Heidi R. Fuller, Lea Langer Horvat, Davor Mayer, Janja Kopić, Klara Pintarić, Mirjana Babić Leko, Mihaela Pravica, Željka Krsnik, Darko Marčinko, Marina Šagud, Patrick R. Hof, Mihovil Mladinov, Goran Šimić

Biomolecules. 2024 Mar; 14(3): 302. Published online 2024 Mar 4. doi: 10.3390/biom14030302

PMCID:: PMC10968053

Abstract Article PDF–4.6M

Select item 107254832.

NLRP1- A CINDERELLA STORY: a perspective of recent advances in NLRP1 and the questions they raise

Kristian Barry, Christopher Murphy, Ashley Mansell

Commun Biol. 2023; 6: 1274. Published online 2023 Dec 16. doi: 10.1038/s42003-023-05684-3

PMCID:: PMC10725483

Abstract Article PDF–688K

Select item 101951803.

The Relationship between the Serum NLRP1 Level and Coronary Lesions in Patients with Coronary Artery Disease

Jing Zong, Yixiao Wang, Siyu Pan, Yiming Yang, Jingfeng Peng, Fangfang Li, Luhong Xu, Shanshan Li, Wenhao Qian

Int J Clin Pract. 2023; 2023: 2250055. Published online 2023 May 11. doi: 10.1155/2023/2250055

PMCID:: PMC10195180

Abstract Article PDF–291K

Select item 99960114.

The NLRP1 inflammasome in skin diseases

Marc Burian, Morna F. Schmidt, Amir S. Yazdi

Front Immunol. 2023; 14: 1111611. Published online 2023 Feb 23. doi: 10.3389/fimmu.2023.1111611

PMCID:: PMC9996011

Abstract Article PDF–1005K

Select item 98005825.

High p62 expression suppresses the NLRP1 inflammasome and increases stress resistance in cutaneous SCC cells

Paulina Hennig, Michela Di Filippo, Gilles Bilfeld, Mark Mellett, Hans-Dietmar Beer

Cell Death Dis. 2022 Dec; 13(12): 1077. Published online 2022 Dec 29. doi: 10.1038/s41419-022-05530-0

PMCID:: PMC9800582

Abstract Article PDF–2.7M

Select item 96847696.

A common variant close to the “tripwire” linker region of NLRP1 contributes to severe COVID-19

Vinicius N. C. Leal, Leandro M. Paulino, Raylane A. G. Cambui, Thiago G. Zupelli, Suemy M. Yamada, Leonardo A. T. Oliveira, Valéria de F. Dutra, Carolina B. Bub, Araci M. Sakashita, Ana Paula H. Yokoyama, José M. Kutner, Camila A. Vieira, Wellyngton M. de S. Santiago, Milena M. S. Andrade, Franciane M. E. Teixeira, Ricardo W. Alberca, Sarah C. Gozzi-Silva, Tatiana M. Yendo, Lucas C. Netto, Alberto J. S. Duarte, Maria N. Sato, James Venturini, Alessandra Pontillo

Inflamm Res. 2022 Nov 23 : 1–8. doi: 10.1007/s00011-022-01670-3 [Epub ahead of print]

PMCID:: PMC9684769

Abstract Article PDF–1.0M

Select item 96034397.

NLRP1 in Cutaneous SCCs: An Example of the Complex Roles of Inflammasomes in Cancer Development

Michela Di Filippo, Paulina Hennig, Tugay Karakaya, Marta Slaufova, Hans-Dietmar Beer

Int J Mol Sci. 2022 Oct; 23(20): 12308. Published online 2022 Oct 14. doi: 10.3390/ijms232012308

PMCID:: PMC9603439

Abstract Article PDF–2.5M

Select item 88998638.

The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells

Andrew R. Griswold, Hsin-Che Huang, Daniel A. Bachovchin

Invest Ophthalmol Vis Sci. 2022 Mar; 63(3): 2. Published online 2022 Mar 3. doi: 10.1167/iovs.63.3.2

PMCID:: PMC8899863

Abstract Article PDF–1.9M

Select item 81689559.

NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity

Jonas Moecking, Pawat Laohamonthonkul, Katelyn Chalker, Marquitta J. White, Cassandra R. Harapas, Chien-Hsiung Yu, Sophia Davidson, Katja Hrovat-Schaale, Donglei Hu, Celeste Eng, Scott Huntsman, Dale J. Calleja, Jay C. Horvat, Phil M. Hansbro, Robert J.J. O’Donoghue, Jenny P. Ting, Esteban G. Burchard, Matthias Geyer, Motti Gerlic, Seth L. Masters

J Allergy Clin Immunol. 2021 Jun; 147(6): 2134–2145.e20. doi: 10.1016/j.jaci.2020.12.636

PMCID:: PMC8168955

Abstract Article PDF–3.5M

Select item 801963810.

Autophagy in the HTR-8/SVneo Cell Oxidative Stress Model Is Associated with the NLRP1 Inflammasome

Meihe Li, Tao Sun, Xiaoling Wu, Peng An, Xili Wu, Huimin Dang

Oxid Med Cell Longev. 2021; 2021: 2353504. Published online 2021 Mar 27. doi: 10.1155/2021/2353504

PMCID:: PMC8019638

Abstract Article PDF–1.5M

Select item 799369911.

Low expression of NLRP1 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients

Edward Shen, Ying Han, Changjing Cai, Ping Liu, Yihong Chen, Le Gao, Qiaoqiao Huang, Hong Shen, Shan Zeng, Min He

Aging (Albany NY) 2021 Mar 15; 13(5): 7570–7588. Published online 2021 Mar 3. doi: 10.18632/aging.202620

PMCID:: PMC7993699

Abstract Article PDF–2.6M

Select item 785773212.

Diverse viral proteases activate the NLRP1 inflammasome

Brian V Tsu, Christopher Beierschmitt, Andrew P Ryan, Rimjhim Agarwal, Patrick S Mitchell, Matthew D Daugherty

eLife. 2021; 10: e60609. Published online 2021 Jan 7. doi: 10.7554/eLife.60609

PMCID:: PMC7857732

Abstract Article PDF–6.0M

Select item 780147313.

Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Zhihao Xu, Ying Zhou, Muziying Liu, Huan Ma, Liangqi Sun, Ayesha Zahid, Yulei Chen, Rongbin Zhou, Minjie Cao, Dabao Wu, Weidong Zhao, Bofeng Li, Tengchuan Jin

Cell Death Dis. 2021 Jan; 12(1): 57. Published online 2021 Jan 11. doi: 10.1038/s41419-020-03342-8

PMCID:: PMC7801473

Abstract Article PDF–7.5M

Select item 748466814.

Fine Particulate Matter (PM_2.5) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells

Liu Dong, Ruiming Hu, Dandan Yang, Jinzhuo Zhao, Haidong Kan, Jianguo Tan, Ming Guan, Zhihua Kang, Feng Xu

Int J Med Sci. 2020; 17(14): 2200–2206. Published online 2020 Sep 1. doi: 10.7150/ijms.46962

PMCID:: PMC7484668

Abstract Article PDF–1.0M

Select item 682644015.

Association of NLRP1 Coding Polymorphism with Lung Function and Serum IL-1β Concentration in Patients Diagnosed with Chronic Obstructive Pulmonary Disease (COPD)

Petar Ozretić, Miguel Inacio da Silva Filho, Calogerina Catalano, Irena Sokolović, Andrea Vukić-Dugac, Maja Šutić, Matea Kurtović, Gordana Bubanović, Sanja Popović-Grle, Sanda Skrinjarić-Cincar, Oliver Vugrek, Irena Jukić, Lada Rumora, Martina Bosnar, Miroslav Samaržija, Robert Bals, Marko Jakopović, Asta Försti, Jelena Knežević

Genes (Basel) 2019 Oct; 10(10): 783. Published online 2019 Oct 9. doi: 10.3390/genes10100783

PMCID:: PMC6826440

Abstract Article PDF–1.2M

Select item 680061216.

The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries

Patrick S. Mitchell, Andrew Sandstrom, Russell E. Vance

Curr Opin Immunol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Curr Opin Immunol. 2019 Oct; 60: 37–45. Published online 2019 May 20. doi: 10.1016/j.coi.2019.04.015

PMCID:: PMC6800612

Abstract Article PDF–1.1M

Select item 675461817.

Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis

Scott B. Drutman, Filomeen Haerynck, Franklin L. Zhong, David Hum, Nicholas J. Hernandez, Serkan Belkaya, Franck Rapaport, Sarah Jill de Jong, David Creytens, Simon J. Tavernier, Katrien Bonte, Sofie De Schepper, Jutte van der Werff ten Bosch, Lazaro Lorenzo-Diaz, Andy Wullaert, Xavier Bossuyt, Gérard Orth, Vincent R. Bonagura, Vivien Béziat, Laurent Abel, Emmanuelle Jouanguy, Bruno Reversade, Jean Laurent-Casanova

Proc Natl Acad Sci U S A. 2019 Sep 17; 116(38): 19055–19063. Published online 2019 Sep 4. doi: 10.1073/pnas.1906184116

PMCID:: PMC6754618

Abstract Article PDF–1.1M

Select item 666469918.

Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes

Xiaoxiao Sun, Ying Xia, Yue Liu, Yanfei Wang, Shuoming Luo, Jian Lin, Gan Huang, Xia Li, Zhiguo Xie, Zhiguang Zhou

J Diabetes Res. 2019; 2019: 7405120. Published online 2019 Jul 14. doi: 10.1155/2019/7405120

PMCID:: PMC6664699

Abstract Article PDF–682K

Select item 568204719.

NLRP1 Overexpression Is Correlated with the Tumorigenesis and Proliferation of Human Breast Tumor

Yuxian Wei, Hongyan Huang, Zhu Qiu, Hongzhong Li, Jinxiang Tan, Guosheng Ren, Xiaoyi Wang

Biomed Res Int. 2017; 2017: 4938473. Published online 2017 Oct 29. doi: 10.1155/2017/4938473

PMCID:: PMC5682047

Abstract Article PDF–3.4M

Select item 466973920.

DAC can restore expression of NALP1 to suppress tumor growth in colon cancer

C Chen, B Wang, J Sun, H Na, Z Chen, Z Zhu, L Yan, S Ren, Y Zuo

Cell Death Dis. 2015 Jan; 6(1): e1602. Published online 2015 Jan 22. doi: 10.1038/cddis.2014.532

PMCID:: PMC4669739

Abstract Article PDF–2.4M

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