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Select item 95516791.

Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome

Brian J. Golbourn, Matthew E. Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E. Mbah, Nisha Kabir, Ann-Catherine J. Stanton, Abigail L. Locke, Stephanie M. Casillo, Yanhua Zhao, Lauren M. Sanders, Allison Cheney, Steven J. Mullett, Apeng Chen, Michelle Wassell, Anthony Andren, Jennifer Perez, Esther P. Jane, Daniel R. David Premkumar, Robert F. Koncar, Shideh Mirhadi, Lauren H. McCarl, Yue-Fang Chang, Yijen L. Wu, Taylor A. Gatesman, Andrea F. Cruz, Michal Zapotocky, Baoli Hu, Gary Kohanbash, Xiuxing Wang, Alenoush Vartanian, Michael F. Moran, Frank Lieberman, Nduka M. Amankulor, Stacy G. Wendell, Olena M. Vaske, Ashok Panigrahy, James Felker, Kelsey C. Bertrand, Claudia L. Kleinman, Jeremy N. Rich, Robert M. Friedlander, Alberto Broniscer, Costas Lyssiotis, Nada Jabado, Ian F. Pollack, Stephen C. Mack, Sameer Agnihotri

Nat Cancer. Author manuscript; available in PMC 2022 Oct 11.

Published in final edited form as: Nat Cancer. 2022 May; 3(5): 629–648. Published online 2022 Apr 14. doi: 10.1038/s43018-022-00348-3

Correction in:: Nat Cancer. 2022 Jun 23

PMCID:: PMC9551679

Abstract Article PDF–6.3M

Select item 29058602.

Changes in the Expression of Methionine Adenosyltransferase Genes and S-adenosylmethionine Homeostasis during Hepatic Stellate Cell Activation

Komal Ramani, Heping Yang, John Kuhlenkamp, Lauda Tomasi, Hidekazu Tsukamoto, José M. Mato, Shelly C. Lu

Hepatology. Author manuscript; available in PMC 2011 Mar 1.

Published in final edited form as: Hepatology. 2010 Mar; 51(3): 986–995. doi: 10.1002/hep.23411

PMCID:: PMC2905860

Abstract Article PDF–716K

Select item 66312353.

Alterations of Methionine Metabolism as Potential Targets for the Prevention and Therapy of Hepatocellular Carcinoma

Rosa M. Pascale, Graziella Peitta, Maria M. Simile, Francesco Feo

Medicina (Kaunas) 2019 Jun; 55(6): 296. Published online 2019 Jun 21. doi: 10.3390/medicina55060296

PMCID:: PMC6631235

Abstract Article PDF–3.0M

Select item 44218174.

Acetylation of MAT IIα represses tumour cell growth and is decreased in human hepatocellular cancer

Hong-Bin Yang, Ying-Ying Xu, Xiang-Ning Zhao, Shao-Wu Zou, Ye Zhang, Min Zhang, Jin-Tao Li, Feng Ren, Li-Ying Wang, Qun-Ying Lei

Nat Commun. 2015 Apr 30; 6: 6973. Published online 2015 Apr 30. doi: 10.1038/ncomms7973

PMCID:: PMC4421817

Abstract Article PDF–1.4M

Select item 92134455.

Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA

Jin-Tao Li, Hai Yang, Ming-Zhu Lei, Wei-Ping Zhu, Ying Su, Kai-Yue Li, Wen-Ying Zhu, Jian Wang, Lei Zhang, Jia Qu, Lei Lv, Hao-Jie Lu, Zheng-Jun Chen, Lu Wang, Miao Yin, Qun-Ying Lei

Signal Transduct Target Ther. 2022; 7: 192. Published online 2022 Jun 22. doi: 10.1038/s41392-022-01017-8

Correction in:: Signal Transduct Target Ther. 2022; 7: 401.

PMCID:: PMC9213445

Abstract Article PDF–4.2M

Select item 56666216.

Methionine metabolism is essential for SIRT1‐regulated mouse embryonic stem cell maintenance and embryonic development

Shuang Tang, Yi Fang, Gang Huang, Xiaojiang Xu, Elizabeth Padilla‐Banks, Wei Fan, Qing Xu, Sydney M Sanderson, Julie F Foley, Scotty Dowdy, Michael W McBurney, David C Fargo, Carmen J Williams, Jason W Locasale, Ziqiang Guan, Xiaoling Li

EMBO J. 2017 Nov 2; 36(21): 3175–3193. Published online 2017 Oct 11. doi: 10.15252/embj.201796708

PMCID:: PMC5666621

Abstract Article PDF–2.9M

Select item 36503947.

Methionine Adenosyltransferase II-dependent Histone H3K9 Methylation at the COX-2 Gene Locus

Yohei Kera, Yasutake Katoh, Mineto Ohta, Mitsuyo Matsumoto, Teruko Takano-Yamamoto, Kazuhiko Igarashi

J Biol Chem. 2013 May 10; 288(19): 13592–13601. Published online 2013 Mar 28. doi: 10.1074/jbc.M112.429738

PMCID:: PMC3650394

Abstract Article PDF–1.2M

Select item 26601448.

Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1α

Siming Li, Erland Arning, Chang Liu, Victor Vitvitsky, Carlos Hernandez, Ruma Banerjee, Teodoro Bottiglieri, Jiandie D. Lin

Am J Physiol Endocrinol Metab. 2009 Mar; 296(3): E543–E548. Published online 2009 Jan 21. doi: 10.1152/ajpendo.90719.2008

PMCID:: PMC2660144

Abstract Article

Select item 64639239.

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia

Teresa Partearroyo, Silvia Murillo-Cuesta, Néstor Vallecillo, Jose M. Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Giacomo Mandruzzato, Adelaida M. Celaya, Steven H. Zeisel, María A. Pajares, Gregorio Varela-Moreiras, Isabel Varela-Nieto

FASEB J. 2019 May; 33(5): 5942–5956. Published online 2019 Feb 12. doi: 10.1096/fj.201801533R

PMCID:: PMC6463923

Abstract Article

Select item 830418510.

IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss

Adelaida M. Celaya, Lourdes Rodríguez-de la Rosa, Jose M. Bermúdez-Muñoz, José M. Zubeldia, Carlos Romá-Mateo, Carlos Avendaño, Federico V. Pallardó, Isabel Varela-Nieto

Cells. 2021 Jul; 10(7): 1686. Published online 2021 Jul 3. doi: 10.3390/cells10071686

PMCID:: PMC8304185

Abstract Article PDF–7.1M

Select item 483027811.

Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2

Paul A. Dutchak, Sunil Laxman, Sandi Jo Estill, Chensu Wang, Yun Wang, Yiguang Wang, Gamze B. Bulut, Jinming Gao, Lily J. Huang, Benjamin P. Tu

Cell Rep. Author manuscript; available in PMC 2016 Jul 21.

Published in final edited form as: Cell Rep. 2015 Jul 21; 12(3): 371–379. Published online 2015 Jul 9. doi: 10.1016/j.celrep.2015.06.042

PMCID:: PMC4830278

Abstract Article PDF–1.4M

Select item 316612912.

Global Analysis of Gene Expression in the Developing Brain of Gtf2ird1 Knockout Mice

Jennifer O'Leary, Lucy R. Osborne

PLoS One. 2011; 6(8): e23868. Published online 2011 Aug 31. doi: 10.1371/journal.pone.0023868

PMCID:: PMC3166129

Abstract Article PDF–436K

Select item 854859613.

Liver and brain differential expression of one-carbon metabolism genes during ontogenesis

Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist

Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9

PMCID:: PMC8548596

Abstract Article PDF–1.3M

Select item 699392514.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 626277715.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 55297116.

Tagging genes with cassette-exchange sites

Gilda Cobellis, Giancarlo Nicolaus, Mariangela Iovino, Antonio Romito, Emanuele Marra, Manlio Barbarisi, Marco Sardiello, Francesco P. Di Giorgio, Nicola Iovino, Massimo Zollo, Andrea Ballabio, Riccardo Cortese

Nucleic Acids Res. 2005; 33(4): e44. Published online 2005 Mar 1. doi: 10.1093/nar/gni045

PMCID:: PMC552971

Abstract Article PDF–382K

Select item 624418317.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 43978318.

Genomic Analysis of Mouse Retinal Development

Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko

PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247

PMCID:: PMC439783

Abstract Article PDF–975K

Select item 633346019.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 538122620.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

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