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Select item 39329131.

Stability of mRNA influences osteoporotic bone mass via CNOT3

Chiho Watanabe, Masahiro Morita, Tadayoshi Hayata, Tetsuya Nakamoto, Chisato Kikuguchi, Xue Li, Yasuhiro Kobayashi, Naoyuki Takahashi, Takuya Notomi, Keiji Moriyama, Tadashi Yamamoto, Yoichi Ezura, Masaki Noda

Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7): 2692–2697. Published online 2014 Feb 3. doi: 10.1073/pnas.1316932111

PMCID:: PMC3932913

Abstract Article PDF–1.0M

Select item 51109972.

Interaction of CCR4–NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis

Cheng-Yuan Yang, Senthilkumar Ramamoorthy, Sören Boller, Marc Rosenbaum, Alfonso Rodriguez Gil, Gerhard Mittler, Yumiko Imai, Keiji Kuba, Rudolf Grosschedl

Genes Dev. 2016 Oct 15; 30(20): 2310–2324. doi: 10.1101/gad.285452.116

PMCID:: PMC5110997

Abstract Article PDF–17M

Select item 45480563.

CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability

Takeshi Inoue, Masahiro Morita, Atsushi Hijikata, Yoko Fukuda-Yuzawa, Shungo Adachi, Kyoichi Isono, Tomokatsu Ikawa, Hiroshi Kawamoto, Haruhiko Koseki, Tohru Natsume, Taro Fukao, Osamu Ohara, Tadashi Yamamoto, Tomohiro Kurosaki

J Exp Med. 2015 Aug 24; 212(9): 1465–1479. doi: 10.1084/jem.20150384

PMCID:: PMC4548056

Abstract Article PDF–3.1M

Select item 86940854.

CNOT3 interacts with the Aurora B and MAPK/ERK kinases to promote survival of differentiating mesendodermal progenitor cells

Moumita Sarkar, Matteo Martufi, Monica Roman-Trufero, Yi-Fang Wang, Chad Whilding, Dirk Dormann, Pierangela Sabbattini, Niall Dillon

Mol Biol Cell. 2021 Dec 1; 32(22): ar40. doi: 10.1091/mbc.E21-02-0089

PMCID:: PMC8694085

Abstract Article PDF–12M

Select item 45940055.

CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins

Toru Suzuki, Chisato Kikuguchi, Sahil Sharma, Toshio Sasaki, Miho Tokumasu, Shungo Adachi, Tohru Natsume, Yumi Kanegae, Tadashi Yamamoto

Sci Rep. 2015; 5: 14779. Published online 2015 Oct 6. doi: 10.1038/srep14779

PMCID:: PMC4594005

Abstract Article PDF–2.4M

Select item 74557216.

Loss of β-cell identity and diabetic phenotype in mice caused by disruption of CNOT3-dependent mRNA deadenylation

Dina Mostafa, Akiko Yanagiya, Eleni Georgiadou, Yibo Wu, Theodoros Stylianides, Guy A. Rutter, Toru Suzuki, Tadashi Yamamoto

Commun Biol. 2020; 3: 476. Published online 2020 Aug 28. doi: 10.1038/s42003-020-01201-y

PMCID:: PMC7455721

Abstract Article PDF–2.4M

Select item 54712377.

The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription

Alfonso Rodríguez-Gil, Olesja Ritter, Vera V. Saul, Jochen Wilhelm, Chen-Yuan Yang, Rudolf Grosschedl, Yumiko Imai, Keiji Kuba, Michael Kracht, M. Lienhard Schmitz

Sci Rep. 2017; 7: 3547. Published online 2017 Jun 14. doi: 10.1038/s41598-017-03708-7

PMCID:: PMC5471237

Abstract Article PDF–5.3M

Select item 41554198.

Identification of Ccr4-Not Complex Components as Regulators of Transition from Partial to Genuine Induced Pluripotent Stem Cells

Masayoshi Kamon, Miyuki Katano, Keiko Hiraki-Kamon, Tomoaki Hishida, Yutaka Nakachi, Yosuke Mizuno, Yasushi Okazaki, Ayumu Suzuki, Masataka Hirasaki, Atsushi Ueda, Masazumi Nishimoto, Hidemasa Kato, Akihiko Okuda

Stem Cells Dev. 2014 Sep 15; 23(18): 2170–2179. Published online 2013 Nov 8. doi: 10.1089/scd.2013.0326

PMCID:: PMC4155419

Abstract Article PDF–691K

Select item 32435899.

Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3^+/− mice

Masahiro Morita, Yuichi Oike, Takeshi Nagashima, Tsuyoshi Kadomatsu, Mitsuhisa Tabata, Toru Suzuki, Takahisa Nakamura, Nobuaki Yoshida, Mariko Okada, Tadashi Yamamoto

EMBO J. 2011 Nov 16; 30(22): 4678–4691. Published online 2011 Sep 6. doi: 10.1038/emboj.2011.320

PMCID:: PMC3243589

Abstract Article PDF–1.2M

Select item 824938810.

Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex

Katsura Minegishi, Benjamin Rothé, Kaoru R. Komatsu, Hiroki Ono, Yayoi Ikawa, Hiromi Nishimura, Takanobu A. Katoh, Eriko Kajikawa, Xiaorei Sai, Emi Miyashita, Katsuyoshi Takaoka, Kana Bando, Hiroshi Kiyonari, Tadashi Yamamoto, Hirohide Saito, Daniel B. Constam, Hiroshi Hamada

Nat Commun. 2021; 12: 4071. Published online 2021 Jul 1. doi: 10.1038/s41467-021-24295-2

PMCID:: PMC8249388

Abstract Article PDF–4.7M

Select item 510651811.

CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State

Xiaofeng Zheng, Pengyi Yang, Brad Lackford, Brian D. Bennett, Li Wang, Hui Li, Yu Wang, Yiliang Miao, Julie F. Foley, David C. Fargo, Ying Jin, Carmen J. Williams, Raja Jothi, Guang Hu

Stem Cell Reports. 2016 Nov 8; 7(5): 897–910. Published online 2016 Oct 13. doi: 10.1016/j.stemcr.2016.09.007

PMCID:: PMC5106518

Abstract Article PDF–2.7M

Select item 378771712.

Cnot1, Cnot2, and Cnot3 Maintain Mouse and Human ESC Identity and Inhibit Extraembryonic Differentiation

Xiaofeng Zheng, Raluca Dumitru, Brad L. Lackford, Johannes M. Freudenberg, Ajeet P. Singh, Trevor K. Archer, Raja Jothi, Guang Hu

Stem Cells. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Stem Cells. 2012 May; 30(5): 910–922. doi: 10.1002/stem.1070

PMCID:: PMC3787717

Abstract Article PDF–3.4M

Select item 524230313.

mTOR regulates the expression of DNA damage response enzymes in long‐lived Snell dwarf, GHRKO, and PAPPA‐KO mice

Graham Dominick, Jacqueline Bowman, Xinna Li, Richard A. Miller, Gonzalo G. Garcia

Aging Cell. 2017 Feb; 16(1): 52–60. Published online 2016 Sep 13. doi: 10.1111/acel.12525

PMCID:: PMC5242303

Abstract Article PDF–895K

Select item 330899214.

Interaction between NANOS2 and the CCR4-NOT Deadenylation Complex Is Essential for Male Germ Cell Development in Mouse

Atsushi Suzuki, Rie Saba, Kei Miyoshi, Yoshinori Morita, Yumiko Saga

PLoS One. 2012; 7(3): e33558. Published online 2012 Mar 20. doi: 10.1371/journal.pone.0033558

PMCID:: PMC3308992

Abstract Article PDF–3.1M

Select item 284049915.

NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs

Atsushi Suzuki, Katsuhide Igarashi, Ken-ichi Aisaki, Jun Kanno, Yumiko Saga

Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8): 3594–3599. Published online 2010 Feb 2. doi: 10.1073/pnas.0908664107

PMCID:: PMC2840499

Abstract Article PDF–1.2M

Select item 195148916.

Depletion of Mammalian CCR4b Deadenylase Triggers Elevation of the p27^Kip1 mRNA Level and Impairs Cell Growth

Masahiro Morita, Toru Suzuki, Takahisa Nakamura, Kazumasa Yokoyama, Takashi Miyasaka, Tadashi Yamamoto

Mol Cell Biol. 2007 Jul; 27(13): 4980–4990. Published online 2007 Apr 23. doi: 10.1128/MCB.02304-06

PMCID:: PMC1951489

Abstract Article PDF–1.1M

Select item 927941417.

A SOX17-PDGFB signaling axis regulates aortic root development

Pengfei Lu, Ping Wang, Bingruo Wu, Yidong Wang, Yang Liu, Wei Cheng, Xuhui Feng, Xinchun Yuan, Miriam M. Atteya, Haleigh Ferro, Yukiko Sugi, Grant Rydquist, Mahdi Esmaily, Jonathan T. Butcher, Ching-Pin Chang, Jack Lenz, Deyou Zheng, Bin Zhou

Nat Commun. 2022; 13: 4065. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31815-1

PMCID:: PMC9279414

Abstract Article PDF–11M

Select item 639844718.

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto

Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146

PMCID:: PMC6398447

Abstract Article

Select item 586818119.

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Jin Li, Su-Ping Deng, Gang Wei, Peng Yu

Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012

PMCID:: PMC5868181

Abstract Article PDF–653K

Select item 344801220.

Transcription factor Foxp3 and its protein partners form a complex regulatory network

Dipayan Rudra, Paul deRoos, Ashutosh Chaudhry, Rachel Niec, Aaron Arvey, Robert M. Samstein, Christina Leslie, Scott A. Shaffer, David R. Goodlett, Alexander Y. Rudensky

Nat Immunol. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: Nat Immunol. 2012 Oct; 13(10): 1010–1019. Published online 2012 Aug 26. doi: 10.1038/ni.2402