PMC Links for Gene (Select 233081) - PMC

Links from Gene

Items: 1 to 20 of 50

<< First< Prev

Page of 3

Select item 107843171.

Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance

Nathalia R.V. Dragano, Edward Milbank, Roberta Haddad-Tóvolli, Pablo Garrido-Gil, Eva Nóvoa, Marcos F. Fondevilla, Valentina Capelli, Ariane Maria Zanesco, Carina Solon, Joseane Morari, Leticia Pires, Ánxela Estevez-Salguero, Daniel Beiroa, Ismael González-García, Olga Barca-Mayo, Carlos Diéguez, Ruben Nogueiras, José L. Labandeira-García, Elisabeth Rexen Ulven, Trond Ulven, Marc Claret, Licio A. Velloso, Miguel López

Mol Metab. 2024 Jan; 79: 101840. Published online 2023 Nov 29. doi: 10.1016/j.molmet.2023.101840

PMCID:: PMC10784317

Abstract Article PDF–3.3M

Select item 101822482.

GPR40 Deficiency Worsens Metabolic Syndrome-Associated Periodontitis in Mice

Yanchun Li, Zhongyang Lu, Cameron L. Kirkwood, Keith L. Kirkwood, Stephen A. Wank, Ai-Jun Li, Maria F. Lopes-Virella, Yan Huang

J Periodontal Res. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: J Periodontal Res. 2023 Jun; 58(3): 575–587. Published online 2023 Feb 17. doi: 10.1111/jre.13107

PMCID:: PMC10182248

Abstract Article PDF–1.8M

Select item 99386163.

Targeting of G-protein coupled receptor 40 alleviates airway hyperresponsiveness through RhoA/ROCK1 signaling pathway in obese asthmatic mice

Xixi Lin, Like Wang, Xiaojie Lu, Yuanyuan Zhang, Rongying Zheng, Ruijie Chen, Weixi Zhang

Respir Res. 2023; 24: 56. Published online 2023 Feb 17. doi: 10.1186/s12931-023-02361-1

PMCID:: PMC9938616

Abstract Article PDF–2.4M

Select item 96357484.

Loss of GPR40 in LDL receptor-deficient mice exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis

Zhongyang Lu, Yanchun Li, Ai-Jun Li, Wing-Kin Syn, Stephen A. Wank, Maria F. Lopes-Virella, Yan Huang

PLoS One. 2022; 17(11): e0277251. Published online 2022 Nov 4. doi: 10.1371/journal.pone.0277251

PMCID:: PMC9635748

Abstract Article PDF–4.7M

Select item 72642945.

A dominant insulin-specific and islet-destructive T-cell response is sufficient to activate CD8 T cells directed against the fatty-acid receptor GPR40

Andreas Spyrantis, Jana Krieger, Katja Stifter, Bernhard Otto Boehm, Reinhold Schirmbeck

Cell Mol Immunol. 2020 Jun; 17(6): 659–661. Published online 2019 Oct 24. doi: 10.1038/s41423-019-0309-y

PMCID:: PMC7264294

Article PDF–903K

Select item 67463876.

GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve

Hikaru Ueno, Ryo Ito, Shin-ichi Abe, Hitomi Ogino, Minoru Maruyama, Hirohisa Miyashita, Yasufumi Miyamoto, Yusuke Moritoh, Yoshiyuki Tsujihata, Koji Takeuchi, Nobuhiro Nishigaki

PLoS One. 2019; 14(9): e0222653. Published online 2019 Sep 16. doi: 10.1371/journal.pone.0222653

PMCID:: PMC6746387

Abstract Article PDF–2.3M

Select item 56501427.

GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent

Michele J. Pachanski, Melissa E. Kirkland, Daniel T. Kosinski, Joel Mane, Boonlert Cheewatrakoolpong, Jiyan Xue, Daphne Szeto, Gail Forrest, Corin Miller, Michelle Bunzel, Christopher W. Plummer, Harry R. Chobanian, Michael W. Miller, Sarah Souza, Brande S. Thomas-Fowlkes, Aimie M. Ogawa, Adam B. Weinglass, Jerry Di Salvo, Xiaoyan Li, Yue Feng, Daniel A. Tatosian, Andrew D. Howard, Steven L. Colletti, Maria E. Trujillo

PLoS One. 2017; 12(10): e0186033. Published online 2017 Oct 20. doi: 10.1371/journal.pone.0186033

PMCID:: PMC5650142

Abstract Article PDF–12M

Select item 56416308.

Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance

Sibylle Sabrautzki, Gabriele Kaiser, Gerhard K.H. Przemeck, Felicia Gerst, Estela Lorza-Gil, Madhura Panse, Tina Sartorius, Miriam Hoene, Susan Marschall, Hans-Ulrich Häring, Martin Hrabě de Angelis, Susanne Ullrich

Mol Metab. 2017 Oct; 6(10): 1304–1312. Published online 2017 Jul 18. doi: 10.1016/j.molmet.2017.07.007

PMCID:: PMC5641630

Abstract Article PDF–867K

Select item 55169859.

Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice

Kazuo Nakamoto, Fuka Aizawa, Kei Miyagi, Takuya Yamashita, Mitsumasa Mankura, Yutaka Koyama, Fumiyo Kasuya, Akira Hirasawa, Takashi Kurihara, Atsuro Miyata, Shogo Tokuyama

PLoS One. 2017; 12(7): e0180610. Published online 2017 Jul 19. doi: 10.1371/journal.pone.0180610

PMCID:: PMC5516985

Abstract Article PDF–5.3M

Select item 493540210.

Featured Article: Deficiency of G-protein coupled receptor 40, a lipid-activated receptor, heightens in vitro- and in vivo-induced murine osteoarthritis

Laurent-Emmanuel Monfoulet, Claire Philippe, Sylvie Mercier, Véronique Coxam, Yohann Wittrant

Exp Biol Med (Maywood) 2015 Jul; 240(7): 854–866. Published online 2015 Jan 13. doi: 10.1177/1535370214565078

PMCID:: PMC4935402

Abstract Article PDF–1.6M

Select item 488855811.

Deletion of GPR40 fatty acid receptor gene in mice blocks mercaptoacetate-induced feeding

Ai-Jun Li, Michael F. Wiater, Qing Wang, Stephen Wank, Sue Ritter

Am J Physiol Regul Integr Comp Physiol. 2016 May 15; 310(10): R968–R974. Published online 2016 Mar 16. doi: 10.1152/ajpregu.00548.2015

PMCID:: PMC4888558

Abstract Article

Select item 471790412.

The G-Protein–Coupled Receptor GPR40 Directly Mediates Long-Chain Fatty Acid–Induced Secretion of Cholecystokinin

ALICE P. LIOU, XINPING LU, YOSHITATSU SEI, XILIN ZHAO, SUSANNE PECHHOLD, RICARDO J. CARRERO, HELEN E. RAYBOULD, STEPHEN WANK

Gastroenterology. Author manuscript; available in PMC 2016 Jan 19.

Published in final edited form as: Gastroenterology. 2011 Mar; 140(3): 903–912. Published online 2010 Oct 16. doi: 10.1053/j.gastro.2010.10.012

PMCID:: PMC4717904

Abstract Article PDF–667K

Select item 433943413.

Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40

Prasanna Karki, Takashi Kurihara, Tomoya Nakamachi, Jun Watanabe, Toshihide Asada, Tatsuki Oyoshi, Seiji Shioda, Megumu Yoshimura, Kazunori Arita, Atsuro Miyata

Mol Pain. 2015; 11: 6. Published online 2015 Feb 12. doi: 10.1186/s12990-015-0003-8

PMCID:: PMC4339434

Abstract Article PDF–3.9M

Select item 386535414.

Hypothalamic GPR40 Signaling Activated by Free Long Chain Fatty Acids Suppresses CFA-Induced Inflammatory Chronic Pain

Kazuo Nakamoto, Takashi Nishinaka, Naoya Sato, Mitsumasa Mankura, Yutaka Koyama, Fumiyo Kasuya, Shogo Tokuyama

PLoS One. 2013; 8(12): e81563. Published online 2013 Dec 12. doi: 10.1371/journal.pone.0081563

PMCID:: PMC3865354

Abstract Article PDF–2.3M

Select item 358508715.

The Free Fatty Acid Receptor G Protein-coupled Receptor 40 (GPR40) Protects from Bone Loss through Inhibition of Osteoclast Differentiation

Fabien Wauquier, Claire Philippe, Laurent Léotoing, Sylvie Mercier, Marie-Jeanne Davicco, Patrice Lebecque, Jérôme Guicheux, Paul Pilet, Elisabeth Miot-Noirault, Vincent Poitout, Thierry Alquier, Véronique Coxam, Yohann Wittrant

J Biol Chem. 2013 Mar 1; 288(9): 6542–6551. Published online 2013 Jan 18. doi: 10.1074/jbc.M112.429084

PMCID:: PMC3585087

Abstract Article PDF–2.2M

Select item 276816716.

Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

Thierry Alquier, Marie-Line Peyot, Martin G. Latour, Melkam Kebede, Christina M. Sorensen, Stephane Gesta, C. Ronald Kahn, Richard D. Smith, Thomas L. Jetton, Thomas O. Metz, Marc Prentki, Vincent Poitout

Diabetes. 2009 Nov; 58(11): 2607–2615. Published online 2009 Aug 31. doi: 10.2337/db09-0362

PMCID:: PMC2768167

Abstract Article PDF–264K

Select item 257039617.

Lack of FFAR1/GPR40 Does Not Protect Mice From High-Fat Diet–Induced Metabolic Disease

Hong Lan, Lizbeth M. Hoos, Li Liu, Glen Tetzloff, Weiwen Hu, Susan J. Abbondanzo, Galya Vassileva, Eric L. Gustafson, Joseph A. Hedrick, Harry R. Davis

Diabetes. 2008 Nov; 57(11): 2999–3006. doi: 10.2337/db08-0596

PMCID:: PMC2570396

Abstract Article PDF–399K

Select item 251849418.

The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding

Melkam Kebede, Thierry Alquier, Martin G. Latour, Meriem Semache, Caroline Tremblay, Vincent Poitout

Diabetes. 2008 Sep; 57(9): 2432–2437. doi: 10.2337/db08-0553

PMCID:: PMC2518494

Abstract Article PDF–428K

Select item 843659919.

GPR40 deficiency is associated with hepatic FAT/CD36 upregulation, steatosis, inflammation, and cell injury in C57BL/6 mice

Zhongyang Lu, Yanchun Li, Wing-Kin Syn, Ai-Jun Li, W. Sue Ritter, Stephen A. Wank, Maria F. Lopes-Virella, Yan Huang

Am J Physiol Endocrinol Metab. 2021 Jan 1; 320(1): E30–E42. Published online 2020 Oct 26. doi: 10.1152/ajpendo.00257.2020

PMCID:: PMC8436599

Abstract Article

Select item 733836320.

Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms

Daiane F. Engel, Vanessa C. D. Bobbo, Carina S. Solon, Guilherme A. Nogueira, Alexandre Moura-Assis, Natalia F. Mendes, Ariane M. Zanesco, Athanasios Papangelis, Trond Ulven, Licio A. Velloso

Sci Rep. 2020; 10: 11047. Published online 2020 Jul 6. doi: 10.1038/s41598-020-68110-2

PMCID:: PMC7338363

Abstract Article PDF–6.2M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 50

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity