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Items: 1 to 20 of 26

1.
Disrupted BRCA1-PALB2 Interaction Induces Tumor Immunosuppression and T-Lymphocyte Infiltration in Hepatocellular Carcinoma Through cGAS-STING Pathway
Hui Ma, Zhihua Kang, Tzeh Keong Foo, Zhiyuan Shen, Bing Xia
Hepatology. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Hepatology. 2023 Jan 1; 77(1): 33–47. Published online 2022 Feb 15. doi: 10.1002/hep.32335
PMCID:
PMC9271123
AbstractArticlePDF–4.5M
2.
Antiparallel Coiled-Coil Interactions Mediate Homodimerization of the DNA Damage Repair Protein, PALB2
Fei Song, Minxing Li, Gaohua Liu, G.V.T. Swapna, Nourhan S. Daigham, Bing Xia, Gaetano T. Montelionep, Samuel F. Bunting
Biochemistry. Author manuscript; available in PMC 2019 Nov 27.
Published in final edited form as: Biochemistry. 2018 Nov 27; 57(47): 6581–6591. Published online 2018 Nov 8. doi: 10.1021/acs.biochem.8b00789
PMCID:
PMC6652205
AbstractArticlePDF–818K
3.
Evidence of inter-tissue differences in the DNA damage response and the pro-oncogenic role of NFκB in mice with disengaged BRCA1-PALB2 interaction
Amar Hekmat Mahdi, Yanying Huo, Yongmei Tan, Srilatha Simhadri, Gabriele Vincelli, Jie Gao, Shridar Ganesan, Bing Xia
Cancer Res. Author manuscript; available in PMC 2019 Jul 15.
Published in final edited form as: Cancer Res. 2018 Jul 15; 78(14): 3969–3981. Published online 2018 May 8. doi: 10.1158/0008-5472.CAN-18-0388
PMCID:
PMC6050088
AbstractArticlePDF–2.4M
4.
Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development
Huai-Chin Chiang, Xiaowen Zhang, Xiayan Zhao, Chi Zhang, Jerry Chen, Paula Garza, Sabrina Smith, Thomas Ludwig, Richard J. Baer, Rong Li, Yanfen Hu
Sci Rep. 2018; 8: 2731. Published online 2018 Feb 9. doi: 10.1038/s41598-018-21044-2
PMCID:
PMC5807304
AbstractArticlePDF–1.6M
5.
Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer
Yanying Huo, Hong Cai, Irina Teplova, Christian Bowman-Colin, Guanghua Chen, Sandy Price, Nicola Barnard, Shridar Ganesan, Vassiliki Karantza, Eileen White, Bing Xia
Cancer Discov. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Cancer Discov. 2013 Aug; 3(8): 894–907. Published online 2013 May 6. doi: 10.1158/2159-8290.CD-13-0011
PMCID:
PMC3740014
AbstractArticlePDF–6.1M
6.
Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration
Yanying Huo, Akshada Sawant, Yongmei Tan, Amar H Mahdi, Tao Li, Hui Ma, Vrushank Bhatt, Run Yan, Jake Coleman, Cheryl F Dreyfus, Jessie Yanxiang Guo, M. Maral Mouradian, Eileen White, Bing Xia
PLoS Genet. 2022 Apr; 18(4): e1010138. Published online 2022 Apr 11. doi: 10.1371/journal.pgen.1010138
PMCID:
PMC9022806
AbstractArticlePDF–6.4M
7.
Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains
Dongju Park, Reena Shakya, Christopher Koivisto, Jason R. Pitarresi, Matthias Szabolcs, Raleigh Kladney, Ashley Hadjis, Thomas A. Mace, Thomas Ludwig
PLoS One. 2019; 14(12): e0226714. Published online 2019 Dec 26. doi: 10.1371/journal.pone.0226714
PMCID:
PMC6932818
AbstractArticlePDF–4.3M
8.
Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2
Suzanne A. Hartford, Rajanikant Chittela, Xia Ding, Aradhana Vyas, Betty Martin, Sandra Burkett, Diana C. Haines, Eileen Southon, Lino Tessarollo, Shyam K. Sharan
PLoS Genet. 2016 Aug; 12(8): e1006236. Published online 2016 Aug 4. doi: 10.1371/journal.pgen.1006236
PMCID:
PMC4973925
AbstractArticlePDF–15M
9.
A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation
Martijn S Luijsterburg, Dimitris Typas, Marie-Christine Caron, Wouter W Wiegant, Diana van den Heuvel, Rick A Boonen, Anthony M Couturier, Leon H Mullenders, Jean-Yves Masson, Haico van Attikum
eLife. 2017; 6: e20922. Published online 2017 Feb 27. doi: 10.7554/eLife.20922
PMCID:
PMC5328590
AbstractArticlePDF–4.1M
10.
Male Fertility Defect Associated with Disrupted BRCA1-PALB2 Interaction in Mice
Srilatha Simhadri, Shaun Peterson, Dharm S. Patel, Yanying Huo, Hong Cai, Christian Bowman-Colin, Shoreh Miller, Thomas Ludwig, Shridar Ganesan, Mantu Bhaumik, Samuel F. Bunting, Maria Jasin, Bing Xia
J Biol Chem. 2014 Aug 29; 289(35): 24617–24629. Published online 2014 Jul 11. doi: 10.1074/jbc.M114.566141
PMCID:
PMC4148885
AbstractArticlePDF–4.7M
11.
BRCA1 haploinsufficiency is masked by RNF168-mediated chromatin ubiquitylation
Dali Zong, Salomé Adam, Yifan Wang, Hiroyuki Sasanuma, Elsa Callén, Matilde Murga, Amanda Day, Michael J. Kruhlak, Nancy Wong, Meagan Munro, Arnab Ray Chaudhuri, Baktiar Karim, Bing Xia, Shunichi Takeda, Neil Johnson, Daniel Durocher, André Nussenzweig
Mol Cell. Author manuscript; available in PMC 2020 Mar 21.
Published in final edited form as: Mol Cell. 2019 Mar 21; 73(6): 1267–1281.e7. Published online 2019 Jan 28. doi: 10.1016/j.molcel.2018.12.010
PMCID:
PMC6430682
AbstractArticlePDF–2.3M
12.
Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer
Christian Bowman-Colin, Bing Xia, Samuel Bunting, Christiaan Klijn, Rinske Drost, Peter Bouwman, Laura Fineman, Xixi Chen, Aedin C. Culhane, Hong Cai, Scott J. Rodig, Roderick T. Bronson, Jos Jonkers, Andre Nussenzweig, Chryssa Kanellopoulou, David M. Livingston
Proc Natl Acad Sci U S A. 2013 May 21; 110(21): 8632–8637. Published online 2013 May 8. doi: 10.1073/pnas.1305362110
PMCID:
PMC3666744
AbstractArticlePDF–719K
13.
siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/− with susceptibility versus C57BL/6-Trp53+/− mice with resistance to mammary tumors
M Böhringer, K Obermeier, N Griner, D Waldraff, E Dickinson, K Eirich, D Schindler, M Hagen, D J Jerry, L Wiesmüller
Oncogene. 2013 Nov 28; 32(48): 5458–5470. Published online 2013 Feb 25. doi: 10.1038/onc.2013.38
PMCID:
PMC3898496
AbstractArticlePDF–1.6M
14.
Assembly, Verification, and Initial Annotation of the NIA Mouse 7.4K cDNA Clone Set
Vincent VanBuren, Yulan Piao, Dawood B. Dudekula, Yong Qian, Mark G. Carter, Patrick R. Martin, Carole A. Stagg, Uwem C. Bassey, Kazuhiro Aiba, Toshio Hamatani, George J. Kargul, Amber G. Luo, Janet Kelso, Winston Hide, Minoru S.H. Ko
Genome Res. 2002 Dec; 12(12): 1999–2003. doi: 10.1101/gr.633802
PMCID:
PMC187561
AbstractArticlePDF–431K
15.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells
Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin
Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064
PMCID:
PMC165511
AbstractArticlePDF–217K
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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