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Items: 1 to 20 of 94

1.
Enhanced Akt3 kinase activity reduces atherosclerosis in hyperlipidemic mice in a gender-dependent manner
Lifang Zhang, Jessica Altemus, Liang Ding, Olga Cherepanova, Tatiana V. Byzova, Eugene A. Podrez
J Biol Chem. 2023 Dec; 299(12): 105425. Published online 2023 Nov 4. doi: 10.1016/j.jbc.2023.105425
PMCID:
PMC10716582
AbstractArticlePDF–2.3M
2.
Akt3-Mediated Protection Against Inflammatory Demyelinating Disease
Juwen C. DuBois, Alex K. Ray, Ross C. Gruber, Yongwei Zhang, Ranee Aflakpui, Fernando Macian-Juan, Bridget Shafit-Zagardo
Front Immunol. 2019; 10: 1738. Published online 2019 Jul 25. doi: 10.3389/fimmu.2019.01738
PMCID:
PMC6669559
AbstractArticlePDF–6.6M
3.
AKT3 drives adenoid cystic carcinoma development in salivary glands
Katalin Zboray, Julian Mohrherr, Patricia Stiedl, Klemens Pranz, Laura Wandruszka, Beatrice Grabner, Robert Eferl, Richard Moriggl, Dagmar Stoiber, Kazuhito Sakamoto, Kay‐Uwe Wagner, Helmut Popper, Emilio Casanova, Herwig P. Moll
Cancer Med. 2018 Feb; 7(2): 445–453. Published online 2017 Dec 28. doi: 10.1002/cam4.1293
PMCID:
PMC5806106
AbstractArticlePDF–1.2M
4.
PKBγ/AKT3 loss-of-function causes learning and memory deficits and deregulation of AKT/mTORC2 signaling: Relevance for schizophrenia
Kristy R. Howell, Kirsten Floyd, Amanda J. Law
PLoS One. 2017; 12(5): e0175993. Published online 2017 May 3. doi: 10.1371/journal.pone.0175993
PMCID:
PMC5414975
AbstractArticlePDF–2.1M
5.
Genetic Deletion of Akt3 Induces an Endophenotype Reminiscent of Psychiatric Manifestations in Mice
Yan Bergeron, Geneviève Bureau, Marie-Élaine Laurier-Laurin, Eric Asselin, Guy Massicotte, Michel Cyr
Front Mol Neurosci. 2017; 10: 102. Published online 2017 Apr 10. doi: 10.3389/fnmol.2017.00102
PMCID:
PMC5385361
AbstractArticlePDF–3.7M
6.
N-cadherin regulates mammary tumor cell migration through Akt3 suppression
S Chung, J Yao, K Suyama, S Bajaj, X Qian, OD Loudig, EA Eugenin, GR Phillips, RB Hazan
Oncogene. Author manuscript; available in PMC 2015 Mar 6.
Published in final edited form as: Oncogene. 2013 Jan 24; 32(4): 422–430. Published online 2012 Mar 12. doi: 10.1038/onc.2012.65
PMCID:
PMC4351658
AbstractArticlePDF–459K
7.
miR-29 targets Akt3 to reduce proliferation and facilitate differentiation of myoblasts in skeletal muscle development
W Wei, H-B He, W-Y Zhang, H-X Zhang, J-B Bai, H-Z Liu, J-H Cao, K-C Chang, X-Y Li, S-H Zhao
Cell Death Dis. 2013 Jun; 4(6): e668. Published online 2013 Jun 13. doi: 10.1038/cddis.2013.184
PMCID:
PMC3698551
AbstractArticlePDF–2.5M
8.
The Effects of Flavonoid Apigenin on Male Reproductive Health: Inhibition of Spermatogonial Proliferation through Downregulation of Prmt7/Akt3 Pathway
Bingyuan Wang, Mingrui Zhang, Jiankang Guo, Zhiguo Liu, Rong Zhou, Fei Guo, Kui Li, Yulian Mu
Int J Mol Sci. 2021 Nov; 22(22): 12209. Published online 2021 Nov 11. doi: 10.3390/ijms222212209
PMCID:
PMC8621337
AbstractArticlePDF–1.9M
9.
Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47phox
Christos Polytarchou, Maria Hatziapostolou, Tung On Yau, Niki Christodoulou, Philip W. Hinds, Filippos Kottakis, Ioannis Sanidas, Philip N. Tsichlis
Proc Natl Acad Sci U S A. 2020 Nov 17; 117(46): 28806–28815. Published online 2020 Nov 2. doi: 10.1073/pnas.2017830117
PMCID:
PMC7682348
AbstractArticlePDF–1.6M
10.
AKT3 deficiency in M2 macrophages impairs cutaneous wound healing by disrupting tissue remodeling
Song Gu, Hanhao Dai, Xilian Zhao, Chang Gui, Jianchao Gui
Aging (Albany NY) 2020 Apr 30; 12(8): 6928–6946. Published online 2020 Apr 14. doi: 10.18632/aging.103051
PMCID:
PMC7202485
AbstractArticlePDF–2.9M
11.
SIAH1 ubiquitin ligase mediates ubiquitination and degradation of Akt3 in neural development
Hyo Rim Ko, Eun-Ju Jin, Sang Bae Lee, Chung Kwon Kim, Taegwan Yun, Sung-Woo Cho, Kye Won Park, Jee-Yin Ahn
J Biol Chem. 2019 Oct 18; 294(42): 15435–15445. Published online 2019 Aug 30. doi: 10.1074/jbc.RA119.009618
PMCID:
PMC6802513
AbstractArticlePDF–2.9M
12.
Impaired Spatial Learning is Associated with Disrupted Integrity of the White Matter in Akt3 Knockout Mice
He Wang, Bao‐Feng Zhang, Ting‐Ting Zhang, Long Wang, Xiao‐Yan Zou, Yun Xu, Ling Chen, Gui‐Quan Chen
CNS Neurosci Ther. 2017 Jan; 23(1): 99–102. Published online 2016 Sep 27. doi: 10.1111/cns.12647
PMCID:
PMC6492745
ArticlePDF–2.0M
13.
V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
Mercedes Valls Serón, Bart Ferwerda, JooYeon Engelen-Lee, Madelijn Geldhoff, Valery Jaspers, Aeilko H. Zwinderman, Michael W. Tanck, Frank Baas, Arie van der Ende, Matthijs C. Brouwer, Diederik van de Beek
Acta Neuropathol Commun. 2016; 4: 50. Published online 2016 May 18. doi: 10.1186/s40478-016-0320-9
PMCID:
PMC4870776
AbstractArticlePDF–1.7M
14.
MicroRNA-207 enhances radiation-induced apoptosis by directly targeting akt3 in cochlea hair cells
P-x Tan, S-s Du, C Ren, Q-w Yao, R Zheng, R Li, Y-w Yuan
Cell Death Dis. 2014 Oct; 5(10): e1433. Published online 2014 Oct 2. doi: 10.1038/cddis.2014.407
PMCID:
PMC4649514
AbstractArticlePDF–1.8M
15.
AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1
Daniel G. Corum, Philip N. Tsichlis, Robin C. Muise-Helmericks
FASEB J. 2014 Jan; 28(1): 395–407. doi: 10.1096/fj.13-235382
PMCID:
PMC3868834
AbstractArticle
16.
Suppression of inflammatory responses during MOG-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling
Vladislav Tsiperson, Ross C. Gruber, Michael Goldberg, Ayana Jordan, Jason G. Weinger, Fernando Macian, Bridget Shafit-Zagardo
J Immunol. Author manuscript; available in PMC 2014 Feb 15.
Published in final edited form as: J Immunol. 2013 Feb 15; 190(4): 1528–1539. Published online 2013 Jan 18. doi: 10.4049/jimmunol.1201387
PMCID:
PMC3564598
AbstractArticlePDF–2.6M
17.
An important role for Akt3 in platelet activation and thrombosis
Kelly A. O'Brien, Aleksandra Stojanovic-Terpo, Nissim Hay, Xiaoping Du
Blood. 2011 Oct 13; 118(15): 4215–4223. Prepublished online 2011 Aug 5. doi: 10.1182/blood-2010-12-323204
PMCID:
PMC3204738
AbstractArticle
18.
Akt3 Controls VEGF secretion and angiogenesis in ovarian cancer cells
Tiera A. Liby, Perry Spyropoulos, Haley Buff Lindner, Juanita Eldridge, Craig Beeson, Tien Hsu, Robin C. Muise-Helmericks
Int J Cancer. Author manuscript; available in PMC 2013 Feb 1.
Published in final edited form as: Int J Cancer. 2012 Feb 1; 130(3): 532–543. Published online 2011 Apr 20. doi: 10.1002/ijc.26010
PMCID:
PMC3189303
AbstractArticlePDF–1.1M
19.
A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice
Satoko Tokuda, Connie L. Mahaffey, Bobby Monks, Christian R. Faulkner, Morris J. Birnbaum, Steve C. Danzer, Wayne N. Frankel
Hum Mol Genet. 2011 Mar 1; 20(5): 988–999. Published online 2010 Dec 15. doi: 10.1093/hmg/ddq544
PMCID:
PMC3033189
AbstractArticlePDF–457K
20.
Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT’s Role in Complex Brain Disorders and Neurological Disease
Josien Levenga, Helen Wong, Ryan Milstead, Lauren LaPlante, Charles A Hoeffer
Cereb Cortex Commun. 2021; 2(2): tgab036. Published online 2021 May 28. doi: 10.1093/texcom/tgab036
PMCID:
PMC8223503
AbstractArticlePDF–3.0M

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