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Select item 95743791.

Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages

Aleksandar Murgaski, Máté Kiss, Helena Van Damme, Daliya Kancheva, Isaure Vanmeerbeek, Jiri Keirsse, Eva Hadadi, Jan Brughmans, Sana M. Arnouk, Ahmed E.I. Hamouda, Ayla Debraekeleer, Victor Bosteels, Yvon Elkrim, Louis Boon, Sabine Hoves, Niels Vandamme, Sofie Deschoemaeker, Sophie Janssens, Abhishek D. Garg, Greetje Vande Velde, Martina Schmittnaegel, Carola H. Ries, Damya Laoui

Cancer Res. 2022 Oct 17; 82(20): 3785–3801. Published online 2022 Aug 18. doi: 10.1158/0008-5472.CAN-22-0094

PMCID:: PMC9574379

Abstract Article PDF–2.1M

Select item 82006772.

Effect of CpG Depletion of Vector Genome on CD8⁺ T Cell Responses in AAV Gene Therapy

Thais B. Bertolini, Jamie L. Shirley, Irene Zolotukhin, Xin Li, Tsuneyasu Kaisho, Weidong Xiao, Sandeep R. P. Kumar, Roland W. Herzog

Front Immunol. 2021; 12: 672449. Published online 2021 May 31. doi: 10.3389/fimmu.2021.672449

PMCID:: PMC8200677

Abstract Article PDF–2.8M

Select item 79979743.

Learned adaptive multiphoton illumination microscopy for large-scale immune response imaging

Henry Pinkard, Hratch Baghdassarian, Adriana Mujal, Ed Roberts, Kenneth H. Hu, Daniel Haim Friedman, Ivana Malenica, Taylor Shagam, Adam Fries, Kaitlin Corbin, Matthew F. Krummel, Laura Waller

Nat Commun. 2021; 12: 1916. Published online 2021 Mar 26. doi: 10.1038/s41467-021-22246-5

PMCID:: PMC7997974

Abstract Article PDF–1.9M

Select item 48593324.

Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1⁺ DCs in mouse and human and distinguishes them from Langerhans cells

Sabrina Carpentier, Thien-Phong Vu Manh, Rabie Chelbi, Sandrine Henri, Bernard Malissen, Muzlifah Haniffa, Florent Ginhoux, Marc Dalod

J Immunol Methods. 2016 May; 432: 35–49. doi: 10.1016/j.jim.2016.02.023

PMCID:: PMC4859332

Abstract Article PDF–4.6M

Select item 47438315.

Imaging of the cross-presenting dendritic cell subsets in the skin-draining lymph node

Masahiro Kitano, Chihiro Yamazaki, Akiko Takumi, Takashi Ikeno, Hiroaki Hemmi, Noriko Takahashi, Kanako Shimizu, Scott E. Fraser, Katsuaki Hoshino, Tsuneyasu Kaisho, Takaharu Okada

Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4): 1044–1049. Published online 2016 Jan 11. doi: 10.1073/pnas.1513607113

PMCID:: PMC4743831

Abstract Article PDF–1.7M

Select item 105690986.

An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses

Ryotaro Oyama, Harumichi Ishigame, Hiroki Tanaka, Naho Tateshita, Moeko Itazawa, Ryosuke Imai, Naomasa Nishiumi, Jun-ichi Kishikawa, Takayuki Kato, Jessica Anindita, Yoshifumi Nishikawa, Masatoshi Maeki, Manabu Tokeshi, Kota Tange, Yuta Nakai, Yu Sakurai, Takaharu Okada, Hidetaka Akita

ACS Nano. 2023 Oct 10; 17(19): 18758–18774. Published online 2023 Sep 26. doi: 10.1021/acsnano.3c02251

PMCID:: PMC10569098

Abstract Article PDF–8.6M

Select item 102798757.

Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity

Felipe Flores-Santibañez, Sofie Rennen, Dominique Fernández, Clint De Nolf, Evelien Van De Velde, Sandra Gaete González, Camila Fuentes, Carolina Moreno, Diego Figueroa, Álvaro Lladser, Takao Iwawaki, María Rosa Bono, Sophie Janssens, Fabiola Osorio

Front Immunol. 2023; 14: 1209588. Published online 2023 Jun 6. doi: 10.3389/fimmu.2023.1209588

PMCID:: PMC10279875

Abstract Article PDF–6.3M

Select item 100789528.

An OMA1 redox site controls mitochondrial homeostasis, sarcoma growth, and immunogenicity

Richard Miallot, Virginie Millet, Yann Groult, Angelika Modelska, Lydie Crescence, Sandrine Roulland, Sandrine Henri, Bernard Malissen, Nicolas Brouilly, Laurence Panicot-Dubois, Renaud Vincentelli, Gerlind Sulzenbacher, Pascal Finetti, Aurélie Dutour, Jean-Yves Blay, François Bertucci, Franck Galland, Philippe Naquet

Life Sci Alliance. 2023 Jun; 6(6): e202201767. Published online 2023 Apr 5. doi: 10.26508/lsa.202201767

PMCID:: PMC10078952

Abstract Article PDF–3.4M

Select item 84422439.

Optimal CD8⁺ T‐cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses

Sandra Dimonte, Silvia Gimeno‐Brias, Morgan Marsden, Lucy Chapman, Pragati Sabberwal, Mathew Clement, Ian R Humphreys

Immunology. 2021 Oct; 164(2): 279–291. Published online 2021 Jun 13. doi: 10.1111/imm.13368

PMCID:: PMC8442243

Abstract Article PDF–617K

Select item 836366810.

PD-L1⁺ and XCR1⁺ dendritic cells are region-specific regulators of gut homeostasis

Thais G. Moreira, Davide Mangani, Laura M. Cox, Jeffrey Leibowitz, Eduardo. L. C. Lobo, Mariana A. Oliveira, Christian D. Gauthier, Brenda N. Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C. A. Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C. Anderson, Rafael M. Rezende, Ana Maria C. Faria, Howard L. Weiner

Nat Commun. 2021; 12: 4907. Published online 2021 Aug 13. doi: 10.1038/s41467-021-25115-3

PMCID:: PMC8363668

Abstract Article PDF–3.8M

Select item 480430711.

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis

Tomokazu Ohta, Masanaka Sugiyama, Hiroaki Hemmi, Chihiro Yamazaki, Soichiro Okura, Izumi Sasaki, Yuri Fukuda, Takashi Orimo, Ken J. Ishii, Katsuaki Hoshino, Florent Ginhoux, Tsuneyasu Kaisho

Sci Rep. 2016; 6: 23505. Published online 2016 Mar 23. doi: 10.1038/srep23505

PMCID:: PMC4804307

Abstract Article PDF–2.4M

Select item 288283512.

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α⁺ dendritic cells

Karine Crozat, Rachel Guiton, Vanessa Contreras, Vincent Feuillet, Charles-Antoine Dutertre, Erwan Ventre, Thien-Phong Vu Manh, Thomas Baranek, Anne K. Storset, Jacqueline Marvel, Pierre Boudinot, Anne Hosmalin, Isabelle Schwartz-Cornil, Marc Dalod

J Exp Med. 2010 Jun 7; 207(6): 1283–1292. doi: 10.1084/jem.20100223

PMCID:: PMC2882835

Abstract Article PDF–3.8M

Select item 1106117713.

Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses

Hongkui Xiao, Isabel Ulmert, Luisa Bach, Johanna Huber, Hamsa Narasimhan, Ilia Kurochkin, Yinshui Chang, Signe Holst, Urs Mörbe, Lili Zhang, Andreas Schlitzer, Carlos-Filipe Pereira, Barbara U. Schraml, Dirk Baumjohann, Katharina Lahl

Nat Commun. 2024; 15: 3554. Published online 2024 Apr 30. doi: 10.1038/s41467-024-46966-6

PMCID:: PMC11061177

Abstract Article PDF–8.0M

Select item 902217714.

Rotavirus-Induced Expansion of Antigen-Specific CD8 T Cells Does Not Require Signaling via TLR3, MyD88 or the Type I Interferon Receptor

Konjit Getachew Muleta, Isabel Ulmert, Kedir Hussen Hamza, Sharné van Dijl, Joy Nakawesi, Katharina Lahl

Front Immunol. 2022; 13: 814491. Published online 2022 Apr 7. doi: 10.3389/fimmu.2022.814491

PMCID:: PMC9022177

Abstract Article PDF–4.9M

Select item 848862415.

Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure

Natallia Salei, Xingqi Ji, Dalia Pakalniškytė, Vanessa Kuentzel, Stephan Rambichler, Na Li, Markus Moser, Katja Steiger, Thorsten Buch, Hans-Joachim Anders, Barbara U. Schraml

Proc Natl Acad Sci U S A. 2021 Sep 28; 118(39): e2022311118. Published online 2021 Sep 13. doi: 10.1073/pnas.2022311118

PMCID:: PMC8488624

Abstract Article PDF–1.8M

Select item 738136416.

IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy

Ting Zhou, William Damsky, Orr-El Weizman, Meaghan K. McGeary, K. Patricia Hartmann, Connor E. Rosen, Suzanne Fischer, Ruaidhri Jackson, Richard A. Flavell, Jun Wang, Miguel F. Sanmamed, Marcus W. Bosenberg, Aaron M. Ring

Nature. Author manuscript; available in PMC 2020 Dec 24.

Published in final edited form as: Nature. 2020 Jul; 583(7817): 609–614. Published online 2020 Jun 24. doi: 10.1038/s41586-020-2422-6

PMCID:: PMC7381364

Abstract Article PDF–6.7M

Select item 647550317.

A Natural Killer/Dendritic Cell Axis Defines Responsive Tumor Microenvironments in Melanoma

Kevin C. Barry, Joy Hsu, Miranda L. Broz, Francisco J. Cueto, Mikhail Binnewies, Alexis J. Combes, Amanda E. Nelson, Kimberly Loo, Raj Kumar, Michael D. Rosenblum, Michael D. Alvarado, Denise M. Wolf, Dusan Bogunovic, Nina Bhardwaj, Adil I. Daud, Patrick K. Ha, William R. Ryan, Joshua L. Pollack, Bushra Samad, Saurabh Asthana, Vincent Chan, Matthew F. Krummel

Nat Med. Author manuscript; available in PMC 2019 Apr 21.

Published in final edited form as: Nat Med. 2018 Aug; 24(8): 1178–1191. Published online 2018 Jun 25. doi: 10.1038/s41591-018-0085-8

PMCID:: PMC6475503

Abstract Article PDF–1.2M

Select item 628829318.

Novel Cre-Expressing Mouse Strains Permitting to Selectively Track and Edit Type 1 Conventional Dendritic Cells Facilitate Disentangling Their Complexity in vivo

Raphaël Mattiuz, Christian Wohn, Sonia Ghilas, Marc Ambrosini, Yannick O. Alexandre, Cindy Sanchez, Anissa Fries, Thien-Phong Vu Manh, Bernard Malissen, Marc Dalod, Karine Crozat

Front Immunol. 2018; 9: 2805. Published online 2018 Dec 4. doi: 10.3389/fimmu.2018.02805

PMCID:: PMC6288293

Abstract Article PDF–3.0M

Select item 846380319.

Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone

Nathalie Diener, Jean-Fred Fontaine, Matthias Klein, Thomas Hieronymus, Florian Wanke, Florian C. Kurschus, Andreas Ludwig, Carl Ware, Paul Saftig, Tobias Bopp, Björn E. Clausen, Ronald A. Backer

Proc Natl Acad Sci U S A. 2021 Sep 21; 118(38): e2111234118. Published online 2021 Sep 15. doi: 10.1073/pnas.2111234118

PMCID:: PMC8463803

Abstract Article PDF–3.3M

Select item 767144320.

Visualizing Synaptic Transfer of Tumor Antigens Amongst Dendritic Cells

Megan K. Ruhland, Edward W. Roberts, En Cai, Adriana M. Mujal, Kyle Marchuk, Casey Beppler, David Nam, Nina K. Serwas, Mikhail Binnewies, Matthew F. Krummel

Cancer Cell. Author manuscript; available in PMC 2021 Jun 8.

Published in final edited form as: Cancer Cell. 2020 Jun 8; 37(6): 786–799.e5. doi: 10.1016/j.ccell.2020.05.002

PMCID:: PMC7671443

Abstract Article PDF–3.2M

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