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Select item 33984951.

SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU)

Barbara P. Vistica, Guangpu Shi, Lindsey Nugent, Cuiyan Tan, Amnon Altman, Igal Gery

Mol Vis. 2012; 18: 1858–1864. Published online 2012 Jul 7.

PMCID:: PMC3398495

Abstract Article PDF–950K

Select item 28218722.

SLAT/Def6 Plays a Critical Role in the Development of Th17 Cell-Mediated Experimental Autoimmune Encephalomyelitis

Ann J. Canonigo-Balancio, Camille Fos, Thomas Prod’homme, Stéphane Bécart, Amnon Altman

J Immunol. Author manuscript; available in PMC 2010 Feb 15.

Published in final edited form as: J Immunol. 2009 Dec 1; 183(11): 7259. Published online 2009 Nov 13. doi: 10.4049/jimmunol.0902573

PMCID:: PMC2821872

Abstract Article PDF–1.9M

Select item 19244953.

SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca²⁺/NFAT signaling

Stéphane Bécart, Céline Charvet, Ann J. Canonigo Balancio, Carl De Trez, Yoshihiko Tanaka, Wei Duan, Carl Ware, Michael Croft, Amnon Altman

J Clin Invest. 2007 Aug 1; 117(8): 2164–2175. Published online 2007 Jul 26. doi: 10.1172/JCI31640

PMCID:: PMC1924495

Abstract Article PDF–1.8M

Select item 77719614.

Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis

Zhonghao Deng, Courtney Ng, Kazuki Inoue, Ziyu Chen, Yuhan Xia, Xiaoyu Hu, Matthew Greenblatt, Alessandra Pernis, Baohong Zhao

eLife. 2020; 9: e59659. Published online 2020 Dec 29. doi: 10.7554/eLife.59659

PMCID:: PMC7771961

Abstract Article PDF–1.2M

Select item 57071895.

Def-6, a Novel Regulator of Small GTPases in Podocytes, Acts Downstream of Atypical Protein Kinase C (aPKC) λ/ι

Kirstin Worthmann, Michael Leitges, Beina Teng, Marcello Sestu, Irini Tossidou, Thomas Samson, Hermann Haller, Tobias B. Huber, Mario Schiffer

Am J Pathol. 2013 Dec; 183(6): 1945–1959. doi: 10.1016/j.ajpath.2013.08.026

PMCID:: PMC5707189

Abstract Article PDF–2.4M

Select item 54251566.

Def6 restrains osteoclastogenesis and inflammatory bone resorption¹

Nikolaus Binder, Christine Miller, Masaki Yoshida, Kazuki Inoue, Shinichi Nakano, Xiaoyu Hu, Lionel B. Ivashkiv, Georg Schett, Alessandra Pernis, Steven R. Goldring, F. Patrick Ross, Baohong Zhao

J Immunol. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: J Immunol. 2017 May 1; 198(9): 3436–3447. Published online 2017 Mar 17. doi: 10.4049/jimmunol.1601716

PMCID:: PMC5425156

Abstract Article PDF–2.3M

Select item 49991977.

SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells

Tatsiana Ripich, Carlos Andrés Chacón-Martínez, Luise Fischer, Alessandra Pernis, Nadine Kiessling, Annette I. Garbe, Rolf Jessberger

PLoS One. 2016; 11(8): e0161060. Published online 2016 Aug 25. doi: 10.1371/journal.pone.0161060

PMCID:: PMC4999197

Abstract Article PDF–2.6M

Select item 43001148.

Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells

Camille Fos, Stephane Becart, Ann J. Canonigo Balancio, Darren Boehning, Amnon Altman

Sci Signal. Author manuscript; available in PMC 2015 Jan 20.

Published in final edited form as: Sci Signal. 2014 Sep 30; 7(345): ra93. Published online 2014 Sep 30. doi: 10.1126/scisignal.2005565

PMCID:: PMC4300114

Abstract Article PDF–1.3M

Select item 38879789.

SLAT Negatively Regulates RANKL-Induced Osteoclast Differentiation

Bang Ung Youn, Kabsun Kim, Jung Ha Kim, Jongwon Lee, Jang Bae Moon, Inyoung Kim, Yong-Wook Park, Nacksung Kim

Mol Cells. 2013 Sep 30; 36(3): 252–257. Published online 2013 Aug 29. doi: 10.1007/s10059-013-0159-x

PMCID:: PMC3887978

Abstract Article PDF–9.1M

Select item 282516110.

Tyrosine-Phosphorylation-Dependent Translocation of the SLAT Protein to the Immunological Synapse Is Required for NFAT Transcription Factor Activation

Stéphane Bécart, Ann J. Canonigo Balancio, Céline Charvet, Sonia Feau, Caitlin E. Sedwick, Amnon Altman

Immunity. Author manuscript; available in PMC 2010 Feb 19.

Published in final edited form as: Immunity. 2008 Nov 14; 29(5): 704–719. Published online 2008 Oct 30. doi: 10.1016/j.immuni.2008.08.015

PMCID:: PMC2825161

Abstract Article PDF–3.9M

Select item 267325711.

Adaptor Protein SLAT Modulates Fcγ Receptor-mediated Phagocytosis in Murine Macrophages

Harshini Mehta, Michael Glogauer, Stephane Bécart, Amnon Altman, K. Mark Coggeshall

J Biol Chem. 2009 May 1; 284(18): 11882–11891. doi: 10.1074/jbc.M809712200

PMCID:: PMC2673257

Abstract Article PDF–648K

Select item 265394412.

Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases

Qinzhong Chen, Sanjay Gupta, Alessandra B. Pernis

J Leukoc Biol. 2009 Mar; 85(3): 539–543. Published online 2008 Dec 12. doi: 10.1189/jlb.0308219

PMCID:: PMC2653944

Abstract Article

Select item 136134513.

Loss of IRF-4–binding protein leads to the spontaneous development of systemic autoimmunity

Jessica C. Fanzo, Wen Yang, So Young Jang, Sanjay Gupta, Qinzhong Chen, Ayesha Siddiq, Steven Greenberg, Alessandra B. Pernis

J Clin Invest. 2006 Mar 1; 116(3): 703–714. Published online 2006 Feb 9. doi: 10.1172/JCI24096

PMCID:: PMC1361345

Abstract Article PDF–1.3M

Select item 463628514.

IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus

Michela Manni, Sanjay Gupta, Briana G. Nixon, Casey T. Weaver, Rolf Jessberger, Alessandra B. Pernis

PLoS One. 2015; 10(11): e0141927. Published online 2015 Nov 6. doi: 10.1371/journal.pone.0141927

PMCID:: PMC4636285

Abstract Article PDF–3.3M

Select item 352979215.

SLAT regulates CD8⁺ T cell clonal expansion in a Cdc42 and NFAT1 dependent manner

Sonia Feau, Stephen P. Schoenberger, Amnon Altman, Stéphane Bécart

J Immunol. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: J Immunol. 2013 Jan 1; 190(1): 174–183. Published online 2012 Nov 28. doi: 10.4049/jimmunol.1201685

PMCID:: PMC3529792

Abstract Article PDF–3.3M

Select item 292972616.

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

Partha S. Biswas, Sanjay Gupta, Emily Chang, Li Song, Roslynn A. Stirzaker, James K. Liao, Govind Bhagat, Alessandra B. Pernis

J Clin Invest. 2010 Sep 1; 120(9): 3280–3295. Published online 2010 Aug 9. doi: 10.1172/JCI42856

PMCID:: PMC2929726

Abstract Article PDF–2.3M

Select item 942768917.

IL-13Rα1-Mediated Signaling Regulates Age-Associated/Autoimmune B-Cell Expansion and Lupus Pathogenesis

Zhu Chen, Danny Flores Castro, Sanjay Gupta, Swati Phalke, Michela Manni, Juan Rivera-Correa, Rolf Jessberger, Habib Zaghouani, Evgenia Giannopoulou, Tania Pannellini, Alessandra B. Pernis

Arthritis Rheumatol. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Arthritis Rheumatol. 2022 Sep; 74(9): 1544–1555. Published online 2022 Aug 22. doi: 10.1002/art.42146