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Select item 101641451.

NAPE-PLD deletion in stress-TRAPed neurons results in an anxiogenic phenotype

Margaryta Tevosian, Hristo Todorov, Ermelinda Lomazzo, Laura Bindila, Natsuo Ueda, Davide Bassetti, Davide Warm, Sergei Kirischuk, Heiko J. Luhmann, Susanne Gerber, Beat Lutz

Transl Psychiatry. 2023; 13: 152. Published online 2023 May 6. doi: 10.1038/s41398-023-02448-9

PMCID:: PMC10164145

Abstract Article PDF–4.2M

Select item 72473162.

Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D

Geetika Aggarwal, Jonah E. Zarrow, Zahra Mashhadi, C. Robb Flynn, Paige Vinson, C. David Weaver, Sean S. Davies

J Biol Chem. 2020 May 22; 295(21): 7289–7300. Published online 2020 Apr 13. doi: 10.1074/jbc.RA120.013362

PMCID:: PMC7247316

Abstract Article PDF–2.8M

Select item 68286923.

A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration

Francesca Palese, Silvia Pontis, Natalia Realini, Daniele Piomelli

Sci Rep. 2019; 9: 15927. Published online 2019 Nov 4. doi: 10.1038/s41598-019-51799-1

PMCID:: PMC6828692

Abstract Article PDF–4.2M

Select item 66714124.

Enzymatic Machinery for Endocannabinoid Biosynthesis Associated with Calcium Stores in Glutamatergic Axon Terminals

Rita Nyilas, Barna Dudok, Gabriella M. Urbán, Ken Mackie, Masahiko Watanabe, Benjamin F. Cravatt, Tamás F. Freund, István Katona

J Neurosci. 2008 Jan 30; 28(5): 1058–1063. doi: 10.1523/JNEUROSCI.5102-07.2008

PMCID:: PMC6671412

Abstract Article PDF–573K

Select item 63499425.

Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

Amandine Everard, Hubert Plovier, Marialetizia Rastelli, Matthias Van Hul, Alice de Wouters d’Oplinter, Lucie Geurts, Céline Druart, Sylvie Robine, Nathalie M. Delzenne, Giulio G. Muccioli, Willem M. de Vos, Serge Luquet, Nicolas Flamand, Vincenzo Di Marzo, Patrice D. Cani

Nat Commun. 2019; 10: 457. Published online 2019 Jan 28. doi: 10.1038/s41467-018-08051-7

PMCID:: PMC6349942

Abstract Article PDF–3.4M

Select item 55382846.

Leptogenic effects of NAPE require activity of NAPE-hydrolyzing phospholipase D

Zhongyi Chen, Yongqin Zhang, Lilu Guo, Noura Dosoky, Lorenzo de Ferra, Scott Peters, Kevin D. Niswender, Sean S. Davies

J Lipid Res. 2017 Aug; 58(8): 1624–1635. Published online 2017 Jun 8. doi: 10.1194/jlr.M076513

PMCID:: PMC5538284

Abstract Article PDF–1.2M

Select item 49094777.

Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain

Emma Leishman, Ken Mackie, Serge Luquet, Heather B Bradshaw

Biochim Biophys Acta. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2016 Jun; 1861(6): 491–500. Published online 2016 Mar 5. doi: 10.1016/j.bbalip.2016.03.003

PMCID:: PMC4909477

Abstract Article PDF–1.3M

Select item 30637318.

Proinflammatory Stimuli Control N-Acylphosphatidylethanolamine-Specific Phospholipase D Expression in Macrophages

Chenggang Zhu, Carlos Solorzano, Saurabh Sahar, Natalia Realini, Ernest Fung, Paolo Sassone-Corsi, Daniele Piomelli

Mol Pharmacol. 2011 Apr; 79(4): 786–792. doi: 10.1124/mol.110.070201

PMCID:: PMC3063731

Abstract Article PDF–799K

Select item 27240389.

Capsaicin-sensitive primary sensory neurons in the mouse express N-Acyl phosphatidylethanolamine phospholipase D

B. Nagy, C. Fedonidis, A. Photiou, J. Wahba, C.C. Paule, D. Ma, L. Buluwela, I. Nagy

Neuroscience. 2009 Jun 30; 161(2-3): 572–577. doi: 10.1016/j.neuroscience.2009.03.047

PMCID:: PMC2724038

Abstract Article

Select item 118455710.

Mammalian cells stably overexpressing N-acylphosphatidylethanolamine-hydrolysing phospholipase D exhibit significantly decreased levels of N-acylphosphatidylethanolamines

Yasuo Okamoto, Jun Morishita, Jun Wang, Patricia C. Schmid, Randy J. Krebsbach, Harald H. O. Schmid, Natsuo Ueda

Biochem J. 2005 Jul 1; 389(Pt 1): 241–247. Prepublished online 2005 Mar 10. Published online 2005 Jun 21. doi: 10.1042/BJ20041790

PMCID:: PMC1184557

Abstract Article PDF–116K

Select item 729129811.

Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism

Charlotte Lefort, Martin Roumain, Matthias Van Hul, Marialetizia Rastelli, Rita Manco, Isabelle Leclercq, Nathalie M. Delzenne, Vincenzo Di Marzo, Nicolas Flamand, Serge Luquet, Cristoforo Silvestri, Giulio G. Muccioli, Patrice D. Cani

Cells. 2020 May; 9(5): 1247. Published online 2020 May 18. doi: 10.3390/cells9051247

PMCID:: PMC7291298

Abstract Article PDF–5.3M

Select item 438270712.

Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota

Lucie Geurts, Amandine Everard, Matthias Van Hul, Ahmed Essaghir, Thibaut Duparc, Sébastien Matamoros, Hubert Plovier, Julien Castel, Raphael G. P. Denis, Marie Bergiers, Céline Druart, Mireille Alhouayek, Nathalie M. Delzenne, Giulio G. Muccioli, Jean-Baptiste Demoulin, Serge Luquet, Patrice D. Cani

Nat Commun. 2015 Mar 11; 6: 6495. Published online 2015 Mar 11. doi: 10.1038/ncomms7495

PMCID:: PMC4382707

Abstract Article PDF–3.5M

Select item 379361913.

Isolevuglandin-modified phosphatidylethanolamine is metabolized by NAPE-hydrolyzing phospholipase D

Lilu Guo, Stephen D. Gragg, Zhongyi Chen, Yongqin Zhang, Venkataraman Amarnath, Sean S. Davies

J Lipid Res. 2013 Nov; 54(11): 3151–3157. doi: 10.1194/jlr.M042556

PMCID:: PMC3793619

Abstract Article PDF–749K

Select item 349683714.

Cannabinoid-1 (CB1) receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting NAPE-PLD terminals

Virginia M. Pickel, Eli T. Shobin, Diane A. Lane, Ken Mackie

Neuroscience. Author manuscript; available in PMC 2013 Dec 27.

Published in final edited form as: Neuroscience. 2012 Dec 27; 227: 10–21. Published online 2012 Jul 31. doi: 10.1016/j.neuroscience.2012.07.050

PMCID:: PMC3496837

Abstract Article PDF–5.7M

Select item 294684115.

Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo

Gabriel M. Simon, Benjamin F. Cravatt

Mol Biosyst. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Mol Biosyst. 2010 Aug; 6(8): 1411–1418. Published online 2010 Apr 14. doi: 10.1039/c000237b

PMCID:: PMC2946841

Abstract Article PDF–784K

Select item 153854516.

Inactivation of N-Acyl Phosphatidylethanolamine Phospholipase D Reveals Multiple Mechanisms for the Biosynthesis of Endocannabinoids

Donmienne Leung, Alan Saghatelian, Gabriel M. Simon, Benjamin F. Cravatt

Biochemistry. Author manuscript; available in PMC 2006 Aug 9.

Published in final edited form as: Biochemistry. 2006 Apr 18; 45(15): 4720–4726. doi: 10.1021/bi060163l

PMCID:: PMC1538545

Abstract Article PDF–601K

Select item 413623317.

Francisella tularensis LVS Induction of Prostaglandin Biosynthesis by Infected Macrophages Requires Specific Host Phospholipases and Lipid Phosphatases

Aaron R. Navratil, Ashley M. Brummett, Joshua D. Bryan, Matthew D. Woolard

Infect Immun. 2014 Aug; 82(8): 3299–3311. doi: 10.1128/IAI.02060-14

PMCID:: PMC4136233

Abstract Article PDF–1.7M

Select item 353629818.

Molecular Mechanisms of N-Formyl-Methionyl-Leucyl-Phenylalanine-Induced Superoxide Generation and Degranulation in Mouse Neutrophils: Phospholipase D Is Dispensable

Takanobu Sato, Tsunaki Hongu, Megumi Sakamoto, Yuji Funakoshi, Yasunori Kanaho

Mol Cell Biol. 2013 Jan; 33(1): 136–145. doi: 10.1128/MCB.00869-12

PMCID:: PMC3536298

Abstract Article PDF–2.0M

Select item 513208319.

Evidence for a GPR18 Role in Diurnal Regulation of Intraocular Pressure

Sally Miller, Emma Leishman, Olivia Oehler, Laura Daily, Natalia Murataeva, Jim Wager-Miller, Heather Bradshaw, Alex Straiker

Invest Ophthalmol Vis Sci. 2016 Nov; 57(14): 6419–6426. doi: 10.1167/iovs.16-19437

PMCID:: PMC5132083

Abstract Article PDF–929K

Select item 221954320.

Multiple Pathways Involved in the Biosynthesis of Anandamide

Jie Liu, Lei Wang, Judith Harvey-White, Bill X. Huang, Hee-Yong Kim, Serge Luquet, Richard D. Palmiter, Gerald Krystal, Ravi Rai, Anu Mahadevan, Raj K. Razdan, George Kunos

Neuropharmacology. Author manuscript; available in PMC 2009 Jan 1.

Published in final edited form as: Neuropharmacology. 2008 Jan; 54(1): 1–7. Published online 2007 Jun 6. doi: 10.1016/j.neuropharm.2007.05.020