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Items: 1 to 20 of 21

1.
Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia
Gonçalo C. Pereira, Laura Lee, Nadiia Rawlings, Joke Ouwendijk, Joanne E. Parker, Tatyana N. Andrienko, Jeremy M. Henley, Andrew P. Halestrap
PLoS One. 2020; 15(6): e0234653. Published online 2020 Jun 24. doi: 10.1371/journal.pone.0234653
PMCID:
PMC7313731
AbstractArticlePDF–3.6M
2.
Reducing mitochondrial bound hexokinase II mediates transition from non-injurious into injurious ischemia/reperfusion of the intact heart
Rianne Nederlof, Ebru Gürel-Gurevin, Otto Eerbeek, Chaoqin Xie, G. Sjoerd Deijs, Moritz Konkel, Jun Hu, Nina C. Weber, Cees A. Schumacher, Antonius Baartscheer, Egbert G. Mik, Markus W. Hollmann, Fadi G. Akar, Coert J. Zuurbier
J Physiol Biochem. 2016; 73(3): 323–333. Published online 2017 Mar 3. doi: 10.1007/s13105-017-0555-3
Correction in:
J Physiol Biochem. 2017; 73(4): 623.
PMCID:
PMC5534207
AbstractArticlePDF–1.0M
3.
Extent of Mitochondrial Hexokinase II Dissociation During Ischemia Correlates With Mitochondrial Cytochrome c Release, Reactive Oxygen Species Production, and Infarct Size on Reperfusion
Philippe Pasdois, Joanne Elizabeth Parker, Andrew Philip Halestrap
J Am Heart Assoc. 2013 Feb; 2(1): e005645. Published online 2013 Feb 22. doi: 10.1161/JAHA.112.005645
PMCID:
PMC3603240
AbstractArticlePDF–1.6M
4.
Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy
Jialiang Lin, Longjie Wang, Yuhao Wu, Qian Xiang, Yongzhao Zhao, Xuanqi Zheng, Shuai Jiang, Zhuoran Sun, Dongwei Fan, Weishi Li
Exp Mol Med. 2024 Mar; 56(3): 747–759. Published online 2024 Mar 27. doi: 10.1038/s12276-024-01196-0
PMCID:
PMC10984922
AbstractArticlePDF–14M
5.
Fiber type-specific effects of acute exercise on insulin-stimulated AS160 phosphorylation in insulin-resistant rat skeletal muscle
Mark W. Pataky, Sydney L. Van Acker, Rhea Dhingra, Marina M. Freeburg, Edward B. Arias, Kentaro Oki, Haiyan Wang, Jonas T. Treebak, Gregory D. Cartee
Am J Physiol Endocrinol Metab. 2019 Dec 1; 317(6): E984–E998. Published online 2019 Oct 1. doi: 10.1152/ajpendo.00304.2019
PMCID:
PMC6957376
AbstractArticle
6.
Inhibition of miR-143 during ischemia cerebral injury protects neurones through recovery of the hexokinase 2-mediated glucose uptake
Xianzhu Zeng, Na Liu, Jing Zhang, Lei Wang, Zhecheng Zhang, Ju Zhu, Qian Li, Yuwen Wang
Biosci Rep. 2017 Aug 31; 37(4): BSR20170216. Prepublished online 2017 May 18. Published online 2017 Jul 4. doi: 10.1042/BSR20170216
PMCID:
PMC6434090
AbstractArticlePDF–825K
7.
The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation
Mir Hussain Nawaz, Juliana C. Ferreira, Lyudmila Nedyalkova, Haizhong Zhu, César Carrasco-López, Serdal Kirmizialtin, Wael M. Rabeh
Biosci Rep. 2018 Feb 28; 38(1): BSR20171666. Prepublished online 2018 Jan 3. Published online 2018 Feb 21. doi: 10.1042/BSR20171666
PMCID:
PMC5803496
AbstractArticlePDF–2.1M
8.
Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors
Hong Lin, Jin Zeng, Ren Xie, Mark J. Schulz, Rosanna Tedesco, Junya Qu, Karl F. Erhard, James F. Mack, Kaushik Raha, Alan R. Rendina, Lawrence M. Szewczuk, Patricia M. Kratz, Anthony J. Jurewicz, Ted Cecconie, Stan Martens, Patrick J. McDevitt, John D. Martin, Stephenie B. Chen, Yong Jiang, Leng Nickels, Benjamin J. Schwartz, Angela Smallwood, Baoguang Zhao, Nino Campobasso, Yanqiu Qian, Jacques Briand, Cynthia M. Rominger, Catherine Oleykowski, Mary Ann Hardwicke, Juan I. Luengo
ACS Med Chem Lett. 2016 Mar 10; 7(3): 217–222. Published online 2015 Dec 28. doi: 10.1021/acsmedchemlett.5b00214
PMCID:
PMC4789681
AbstractArticlePDF–2.3M
9.
Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production
Rongxue Wu, Eugene Wyatt, Kusum Chawla, Minh Tran, Mohsen Ghanefar, Markku Laakso, Conrad L Epting, Hossein Ardehali
EMBO Mol Med. 2012 Jul; 4(7): 633–646. Published online 2012 Apr 20. doi: 10.1002/emmm.201200240
PMCID:
PMC3407950
AbstractArticlePDF–991K
10.
Subcellular Localization of Hexokinases I and II Directs the Metabolic Fate of Glucose
Scott John, James N. Weiss, Bernard Ribalet
PLoS One. 2011; 6(3): e17674. Published online 2011 Mar 9. doi: 10.1371/journal.pone.0017674
PMCID:
PMC3052386
AbstractArticlePDF–979K
11.
Peroxynitrite Nitrates Adenine Nucleotide Translocase and Voltage-Dependent Anion Channel 1 and Alters their Interactions and Association with Hexokinase II in Mitochondria
Meiying Yang, Yanji Xu, James S. Heisner, Jie Sun, David F. Stowe, Wai-Meng Kwok, Amadou K.S. Camara
Mitochondrion. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Mitochondrion. 2019 May; 46: 380–392. Published online 2018 Nov 1. doi: 10.1016/j.mito.2018.10.002
PMCID:
PMC6487210
AbstractArticlePDF–1.3M
12.
Smad7 dependent expression signature highlights BMP2 and HK2 signaling in HSC transdifferentiation
Bernd Denecke, Lucia Wickert, Yan Liu, Loredana Ciuclan, Steven Dooley, Nadja M Meindl-Beinker
World J Gastroenterol. 2010 Nov 7; 16(41): 5211–5224. Published online 2010 Nov 7. doi: 10.3748/wjg.v16.i41.5211
PMCID:
PMC2975092
AbstractArticlePDF–1.6M
13.
Akt Inhibits Apoptosis Downstream of BID Cleavage via a Glucose-Dependent Mechanism Involving Mitochondrial Hexokinases
Nathan Majewski, Veronique Nogueira, R. Brooks Robey, Nissim Hay
Mol Cell Biol. 2004 Jan; 24(2): 730–740. doi: 10.1128/MCB.24.2.730-740.2004
PMCID:
PMC343797
AbstractArticlePDF–508K
14.
The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia
Philippe Pasdois, Joanne E. Parker, Elinor J. Griffiths, Andrew P. Halestrap
Biochem J. 2011 Jun 1; 436(Pt 2): 493–505. Prepublished online 2011 Mar 17. Published online 2011 May 13. doi: 10.1042/BJ20101957
PMCID:
PMC3195442
AbstractArticlePDF–1.4M
15.
Effects of Tianshu Capsule on Spontaneously Hypertensive Rats as Revealed by 1H-NMR-Based Metabolic Profiling
Jian Gao, Tieshan Wang, Chao Wang, Shuai Wang, Wei Wang, Di Ma, Yongbiao Li, Haibin Zhao, Jianxin Chen
Front Pharmacol. 2019; 10: 989. Published online 2019 Sep 11. doi: 10.3389/fphar.2019.00989
PMCID:
PMC6749043
AbstractArticlePDF–2.0M
16.
Hexokinase-II positively regulates glucose starvation induced autophagy through TORC1 inhibition
David J Roberts, Valerie P Tan-Sah, Eric Y Ding, Jeffery M Smith, Shigeki Miyamoto
Mol Cell. Author manuscript; available in PMC 2015 Feb 20.
Published in final edited form as: Mol Cell. 2014 Feb 20; 53(4): 521–533. Published online 2014 Jan 23. doi: 10.1016/j.molcel.2013.12.019
PMCID:
PMC3943874
AbstractArticlePDF–1.0M
17.
Hexokinase activity is required for recruitment of parkin to depolarized mitochondria
Melissa K. McCoy, Alice Kaganovich, Iakov N. Rudenko, Jinhui Ding, Mark R. Cookson
Hum Mol Genet. 2014 Jan 1; 23(1): 145–156. Published online 2013 Aug 19. doi: 10.1093/hmg/ddt407
PMCID:
PMC3857951
AbstractArticlePDF–1.5M
18.
Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels
Federica Chiara, Diego Castellaro, Oriano Marin, Valeria Petronilli, William S. Brusilow, Magdalena Juhaszova, Steven J. Sollott, Michael Forte, Paolo Bernardi, Andrea Rasola
PLoS One. 2008; 3(3): e1852. Published online 2008 Mar 19. doi: 10.1371/journal.pone.0001852
PMCID:
PMC2267038
AbstractArticlePDF–973K
19.
Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart
Tania Martins-Marques, Sandra Isabel Anjo, Paulo Pereira, Bruno Manadas, Henrique Girão
Mol Cell Proteomics. 2015 Nov; 14(11): 3040–3055. Published online 2015 Aug 27. doi: 10.1074/mcp.M115.052894
PMCID:
PMC4638045
AbstractArticlePDF–2.5M
20.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M

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