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Select item 33573941.

Design, synthesis and biological characterization of novel inhibitors of CD38

Min Dong, Yuan-Qi Si, Shuang-Yong Sun, Xiao-Ping Pu, Zhen-Jun Yang, Liang-Ren Zhang, Li-He Zhang, Fung Ping Leung, Connie Mo Ching. Lam, Anna Ka Yee Kwong, Jianbo Yue, Yeyun Zhou, Irina A. Kriksunov, Quan Hao, Hon Cheung Lee

Org Biomol Chem. Author manuscript; available in PMC 2012 May 21.

Published in final edited form as: Org Biomol Chem. 2011 May 7; 9(9): 3246–3257. Published online 2011 Mar 23. doi: 10.1039/c0ob00768d

PMCID:: PMC3357394

Abstract Article PDF–934K

Select item 26569102.

Decreased ADP-Ribosyl Cyclase Activity in Peripheral Blood Mononuclear Cells from Diabetic Patients with Nephropathy

Michio Ohtsuji, Kunimasa Yagi, Miyuki Shintaku-Kubota, Yukiko Kojima-Koba, Naoko Ito, Masako Sugihara, Naoto Yamaaki, Daisuke Chujo, Atsushi Nohara, Yoshiyu Takeda, Junji Kobayashi, Masakazu Yamagishi, Haruhiro Higashida

Exp Diabetes Res. 2008; 2008: 897508. Published online 2009 Mar 17. doi: 10.1155/2008/897508

PMCID:: PMC2656910

Abstract Article PDF–717K

Select item 17627053.

Identification and Functional Characterization of the Hepatic Stellate Cell CD38 Cell Surface Molecule

Sandra March, Mariona Graupera, María Rosa Sarrias, Francisco Lozano, Pilar Pizcueta, Jaume Bosch, Pablo Engel

Am J Pathol. 2007 Jan; 170(1): 176–187. doi: 10.2353/ajpath.2007.051212

PMCID:: PMC1762705

Abstract Article PDF–1.5M

Select item 5088984.

Autoantibodies against CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) that impair glucose-induced insulin secretion in noninsulin- dependent diabetes patients.

F Ikehata, J Satoh, K Nata, A Tohgo, T Nakazawa, I Kato, S Kobayashi, T Akiyama, S Takasawa, T Toyota, H Okamoto

J Clin Invest. 1998 Jul 15; 102(2): 395–401. doi: 10.1172/JCI1656

PMCID:: PMC508898

Summary PDF–285K

Select item 224205.

Evidence of a role for cyclic ADP-ribose in long-term synaptic depression in hippocampus

Magali Reyes-Harde, Ruth Empson, Barry V. L. Potter, Antony Galione, Patric K. Stanton

Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7): 4061–4066. doi: 10.1073/pnas.96.7.4061

PMCID:: PMC22420

Abstract Article PDF–329K

Select item 97922026.

Downregulation of Sirt6 by CD38 promotes cell senescence and aging

Hongji Zhou, Shihai Liu, NanYang Zhang, Kehua Fang, Jinbao Zong, Yi An, Xiaotian Chang

Aging (Albany NY) 2022 Dec 15; 14(23): 9730–9757. Published online 2022 Dec 6. doi: 10.18632/aging.204425

PMCID:: PMC9792202

Abstract Article PDF–3.0M

Select item 63350177.

Characterization of CD38 in the major cell types of the heart: endothelial cells highly express CD38 with activation by hypoxia-reoxygenation triggering NAD(P)H depletion

James Boslett, Craig Hemann, Fedias L. Christofi, Jay L. Zweier

Am J Physiol Cell Physiol. 2018 Mar 1; 314(3): C297–C309. Published online 2017 Nov 29. doi: 10.1152/ajpcell.00139.2017

PMCID:: PMC6335017

Abstract Article

Select item 29922598.

The Ecto-enzyme CD38 Is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Synthase That Couples Receptor Activation to Ca²⁺ Mobilization from Lysosomes in Pancreatic Acinar Cells

François Cosker, Nathalie Cheviron, Michiko Yamasaki, Alexis Menteyne, Frances E. Lund, Marie-Jo Moutin, Antony Galione, Jose-Manuel Cancela

J Biol Chem. 2010 Dec 3; 285(49): 38251–38259. Published online 2010 Sep 24. doi: 10.1074/jbc.M110.125864

PMCID:: PMC2992259

Abstract Article PDF–2.2M

Select item 27855649.

CD38/cADPR/Ca²⁺ Pathway Promotes Cell Proliferation and Delays Nerve Growth Factor-induced Differentiation in PC12 Cells

Jianbo Yue, Wenjie Wei, Connie M. C. Lam, Yong-Juan Zhao, Min Dong, Liang-Ren Zhang, Li-He Zhang, Hon-Cheung Lee

J Biol Chem. 2009 Oct 23; 284(43): 29335–29342. Published online 2009 Aug 20. doi: 10.1074/jbc.M109.049767

PMCID:: PMC2785564

Abstract Article PDF–1.5M

Select item 122236810.

CD38 is the major enzyme responsible for synthesis of nicotinic acid-adenine dinucleotide phosphate in mammalian tissues.

Eduardo N Chini, Claudia C S Chini, Ichiro Kato, Shin Takasawa, Hiroshi Okamoto

Biochem J. 2002 Feb 15; 362(Pt 1): 125–130. doi: 10.1042/0264-6021:3620125

PMCID:: PMC1222368

Summary PDF–124K

Select item 457717211.

Depletion of NADP(H) due to CD38 activation triggers endothelial dysfunction in the postischemic heart

Levy A. Reyes, James Boslett, Saradhadevi Varadharaj, Francesco De Pascali, Craig Hemann, Lawrence J. Druhan, Giuseppe Ambrosio, Mohamed El-Mahdy, Jay L. Zweier

Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37): 11648–11653. Published online 2015 Aug 21. doi: 10.1073/pnas.1505556112

PMCID:: PMC4577172

Abstract Article PDF–957K

Select item 216948412.

Cd38/Adp-Ribosyl Cyclase: A New Role in the Regulation of Osteoclastic Bone Resorption

Li Sun, Olugbenga A. Adebanjo, Baljit S. Moonga, Susanne Corisdeo, Hindupur K. Anandatheerthavarada, Gopa Biswas, Toshiya Arakawa, Yoshiyuki Hakeda, Antoliy Koval, Bali Sodam, Peter J.R. Bevis, A. James Moser, F. Anthony Lai, Solomon Epstein, Bruce R. Troen, Masayoshi Kumegawa, Mone Zaidi

J Cell Biol. 1999 Sep 6; 146(5): 1161–1172. doi: 10.1083/jcb.146.5.1161

PMCID:: PMC2169484

Abstract Article PDF–340K

Select item 734347113.

CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD⁺/NADH ratio and Sirt3 activity in renal tubular cells in diabetic rats

Yoshio Ogura, Munehiro Kitada, Jing Xu, Itaru Monno, Daisuke Koya

Aging (Albany NY) 2020 Jun 30; 12(12): 11325–11336. Published online 2020 Jun 7. doi: 10.18632/aging.103410

PMCID:: PMC7343471

Abstract Article PDF–1.5M

Select item 554290714.

CD38 promotes angiotensin II‐induced cardiac hypertrophy

Xiao‐Hui Guan, Xuan Hong, Ning Zhao, Xiao‐Hong Liu, Yun‐Fei Xiao, Ting‐Tao Chen, Li‐Bin Deng, Xiao‐Lei Wang, Jian‐Bin Wang, Guang‐Ju Ji, Mingui Fu, Ke‐Yu Deng, Hong‐Bo Xin

J Cell Mol Med. 2017 Aug; 21(8): 1492–1502. Published online 2017 Mar 12. doi: 10.1111/jcmm.13076

PMCID:: PMC5542907

Abstract Article PDF–1.7M

Select item 498336715.

CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway

Xiao-Hui Guan, Xiao-Hong Liu, Xuan Hong, Ning Zhao, Yun-Fei Xiao, Ling-Fang Wang, Ling Tang, Kai Jiang, Yi-Song Qian, Ke-Yu Deng, Guangju Ji, Mingui Fu, Hong-Bo Xin

Oxid Med Cell Longev. 2016; 2016: 7410257. Published online 2016 Jul 31. doi: 10.1155/2016/7410257

PMCID:: PMC4983367

Abstract Article PDF–4.6M

Select item 122313916.

CD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brain.

Claire Ceni, Nathalie Pochon, Virginie Brun, Hélène Muller-Steffner, Annie Andrieux, Didier Grunwald, Francis Schuber, Michel De Waard, Frances Lund, Michel Villaz, Marie-Jo Moutin

Biochem J. 2003 Feb 15; 370(Pt 1): 175–183. doi: 10.1042/BJ20020604

PMCID:: PMC1223139

Summary PDF–245K

Select item 251918617.

ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ET_A and ET_B receptor-induced renal vasoconstriction in vivo

Tiffany L. Thai, William J. Arendshorst

Am J Physiol Renal Physiol. 2008 Aug; 295(2): F360–F368. Published online 2008 Jun 4. doi: 10.1152/ajprenal.00512.2007

PMCID:: PMC2519186

Abstract Article

Select item 189581518.

M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice

Dominik Schenten, Angela Egert, Manolis Pasparakis, Klaus Rajewsky

Blood. 2006 Jun 15; 107(12): 4849–4856. Prepublished online 2006 Feb 21. doi: 10.1182/blood-2005-10-4154

PMCID:: PMC1895815

Abstract Article

Select item 219248519.

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

J Exp Med. 1996 Apr 1; 183(4): 1707–1718. doi: 10.1084/jem.183.4.1707

PMCID:: PMC2192485

Summary PDF–1.5M

Select item 377350520.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561