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Items: 1 to 20 of 65

1.
Chromosomal deletions on 16p11.2 encompassing SH2B1 are associated with accelerated metabolic disease
Ruth Hanssen, Chiara Auwerx, Maarja Jõeloo, Marie C. Sadler, Estonian Biobank Research Team, Elana Henning, Julia Keogh, Rebecca Bounds, Miriam Smith, Helen V. Firth, Zoltán Kutalik, I. Sadaf Farooqi, Alexandre Reymond, Katherine Lawler
Cell Rep Med. 2023 Aug 15; 4(8): 101155. Published online 2023 Aug 15. doi: 10.1016/j.xcrm.2023.101155
PMCID:
PMC10439272
AbstractArticlePDF–4.0M
2.
Association of the SH2B1 rs7359397 Gene Polymorphism with Steatosis Severity in Subjects with Obesity and Non-Alcoholic Fatty Liver Disease
Nuria Perez-Diaz-del-Campo, Itziar Abete, Irene Cantero, Bertha Araceli Marin-Alejandre, J. Ignacio Monreal, Mariana Elorz, José Ignacio Herrero, Alberto Benito-Boillos, Jose I. Riezu-Boj, Fermín I. Milagro, Josep A. Tur, J. Alfredo Martinez, M. Angeles Zulet
Nutrients. 2020 May; 12(5): 1260. Published online 2020 Apr 29. doi: 10.3390/nu12051260
PMCID:
PMC7282006
AbstractArticlePDF–1.6M
3.
Replication of the SH2B1 rs7498665 Association with Obesity in a Belgian Study Population
Sigri Beckers, Doreen Zegers, Luc F. Van Gaal, Wim Van Hul
Obes Facts. 2011 Dec; 4(6): 473–477. Published online 2011 Dec 6. doi: 10.1159/000335305
PMCID:
PMC6444515
AbstractArticlePDF–157K
4.
Evidence for association between SH2B1 gene variants and glycated hemoglobin in non-diabetic European American young adults: The Add Health study
LESLIE A LANGE, MARIAELISA GRAFF, ETHAN M LANGE, KRISTIN L YOUNG, ANDREA S RICHARDSON, KAREN L MOHLKE, KARI E NORTH, KATHLEEN M HARRIS, PENNY GORDON-LARSEN
Ann Hum Genet. Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: Ann Hum Genet. 2016 Sep; 80(5): 294–305. doi: 10.1111/ahg.12165
PMCID:
PMC5453181
AbstractArticlePDF–372K
5.
Functional Characterization of Obesity-Associated Variants Involving the α and β Isoforms of Human SH2B1
Laura R. Pearce, Ray Joe, Michael E. Doche, Hsiao-Wen Su, Julia M. Keogh, Elana Henning, Lawrence S. Argetsinger, Elena G. Bochukova, Joel M. Cline, Sumedha Garg, Sadia Saeed, Steven Shoelson, Stephen O'Rahilly, Inês Barroso, Liangyou Rui, I. Sadaf Farooqi, Christin Carter-Su
Endocrinology. 2014 Sep; 155(9): 3219–3226. Published online 2014 Jun 27. doi: 10.1210/en.2014-1264
PMCID:
PMC4138566
AbstractArticle
6.
Signaling Adaptor Protein SH2B1 Enhances Neurite Outgrowth and Accelerates the Maturation of Human Induced Neurons
Yi-Chao Hsu, Su-Liang Chen, Ya-Jean Wang, Yun-Hsiang Chen, Dan-Yen Wang, Linyi Chen, Chia-Hsiang Chen, Hwei-Hsien Chen, Ing-Ming Chiu
Stem Cells Transl Med. 2014 Jun; 3(6): 713–722. Published online 2014 Apr 15. doi: 10.5966/sctm.2013-0111
PMCID:
PMC4039450
AbstractArticlePDF–2.4M
7.
Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants
Anna-Lena Volckmar, Florian Bolze, Ivonne Jarick, Nadja Knoll, André Scherag, Thomas Reinehr, Thomas Illig, Harald Grallert, Heinz-Erich Wichmann, Susanna Wiegand, Heike Biebermann, Heiko Krude, Pamela Fischer-Posovszky, Winfried Rief, Martin Wabitsch, Martin Klingenspor, Johannes Hebebrand, Anke Hinney
BMC Med Genomics. 2012; 5: 65. Published online 2012 Dec 27. doi: 10.1186/1755-8794-5-65
PMCID:
PMC3544595
AbstractArticlePDF–749K
8.
Human SH2B1 mutations are associated with maladaptive behaviors and obesity
Michael E. Doche, Elena G. Bochukova, Hsiao-Wen Su, Laura R. Pearce, Julia M. Keogh, Elana Henning, Joel M. Cline, Anne Dale, Tim Cheetham, Inês Barroso, Lawrence S. Argetsinger, Stephen O’Rahilly, Liangyou Rui, Christin Carter-Su, I. Sadaf Farooqi
J Clin Invest. 2012 Dec 3; 122(12): 4732–4736. Published online 2012 Nov 19. doi: 10.1172/JCI62696
Correction in:
J Clin Invest. 2013 Jan 2; 123(1): 526.
PMCID:
PMC3533535
AbstractArticlePDF–2.2M
9.
Adapter Protein SH2B1β Cross-Links Actin Filaments and Regulates Actin Cytoskeleton
Leah Rider, Jing Tao, Stacy Snyder, Brittany Brinley, Jiayun Lu, Maria Diakonova
Mol Endocrinol. 2009 Jul; 23(7): 1065–1076. Published online 2009 Apr 2. doi: 10.1210/me.2008-0428
PMCID:
PMC2703597
AbstractArticle
10.
The SH2B gene is associated with serum leptin and body fat in normal female twins
Yalda Jamshidi, Harold Snieder, Dongliang Ge, Tim D Spector, Sandra D O’Dell
Obesity (Silver Spring) Author manuscript; available in PMC 2007 Jan 23.
Published in final edited form as: Obesity (Silver Spring). 2007 Jan; 15(1): 5–9. doi: 10.1038/oby.2007.637
PMCID:
PMC1780257
AbstractArticlePDF–302K
11.
Hsa_circ_0075960 Serves as a Sponge for miR-361-3p/SH2B1 in Endometrial Carcinoma
Bo Wu, Ailing Ren, Ying Tian, Ruizhen Huang
Technol Cancer Res Treat. 2020; 19: 1533033820983079. Published online 2020 Dec 24. doi: 10.1177/1533033820983079
PMCID:
PMC7768316
AbstractArticlePDF–1.5M
12.
Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance
Anabel Flores, Lawrence S. Argetsinger, Lukas K.J. Stadler, Alvaro E. Malaga, Paul B. Vander, Lauren C. DeSantis, Ray M. Joe, Joel M. Cline, Julia M. Keogh, Elana Henning, Ines Barroso, Edson Mendes de Oliveira, Gowri Chandrashekar, Erik S. Clutter, Yixin Hu, Jeanne Stuckey, I. Sadaf Farooqi, Martin G. Myers, Jr., Christin Carter-Su
Diabetes. 2019 Nov; 68(11): 2049–2062. Published online 2019 Aug 22. doi: 10.2337/db19-0608
PMCID:
PMC6804625
AbstractArticlePDF–2.3M
13.
The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus
Johanna Giuranna, Anna-Lena Volckmar, Anna Heinen, Triinu Peters, Börge Schmidt, Anne Spieker, Helena Straub, Harald Grallert, Timo D. Müller, Jochen Antel, Ute Haußmann, Hans Klafki, Rui Liangyou, Johannes Hebebrand, Anke Hinney
Obes Facts. 2018 May; 11(2): 93–108. Published online 2018 Apr 10. doi: 10.1159/000486962
Correction in:
Obes Facts. 2018 Jul; 11(3): 176–180.
PMCID:
PMC5981666
AbstractArticlePDF–1.0M
14.
SH2B1 promotes epithelial‐mesenchymal transition through the IRS1/β‐catenin signaling axis in lung adenocarcinoma
Shaoqiang Wang, Yuanda Cheng, Yang Gao, Zhiwei He, Wolong Zhou, Ruimin Chang, Zhenzi Peng, Yingying Zheng, Chaojun Duan, Chunfang Zhang
Mol Carcinog. 2018 May; 57(5): 640–652. Published online 2018 Feb 20. doi: 10.1002/mc.22788
PMCID:
PMC5900930
AbstractArticlePDF–14M
15.
MicroRNA-361-3p suppresses tumor cell proliferation and metastasis by directly targeting SH2B1 in NSCLC
Wei Chen, Jun Wang, Sulai Liu, Shaoqiang Wang, Yuanda Cheng, Wolong Zhou, Chaojun Duan, Chunfang Zhang
J Exp Clin Cancer Res. 2016; 35: 76. Published online 2016 May 10. doi: 10.1186/s13046-016-0357-4
PMCID:
PMC4863317
AbstractArticlePDF–7.0M
16.
Meta-analyses between 18 candidate genetic markers and overweight/obesity
Linlin Tang, Huadan Ye, Qingxiao Hong, Fei Chen, Qinwen Wang, Leiting Xu, Shizhong Bu, Qiong Liu, Meng Ye, Dao Wen Wang, Yifeng Mai, Shiwei Duan
Diagn Pathol. 2014; 9: 56. Published online 2014 Mar 12. doi: 10.1186/1746-1596-9-56
PMCID:
PMC4008255
AbstractArticlePDF–1.6M
17.
The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells
Sabrina Prudente, Eleonora Morini, Jay Larmon, Francesco Andreozzi, Natalia Di Pietro, Angela Nigro, Ernest V Gervino, Gaia Chiara Mannino, Simonetta Bacci, Thomas H Hauser, Emanuele Bellacchio, Gloria Formoso, Fabio Pellegrini, Vittoria Proto, Claudia Menzaghi, Lucia Frittitta, Assunta Pandolfi, Giorgio Sesti, Alessandro Doria, Vincenzo Trischitta
Atherosclerosis. Author manuscript; available in PMC 2013 Jul 31.
Published in final edited form as: Atherosclerosis. 2011 Dec; 219(2): 667–672. Published online 2011 Aug 19. doi: 10.1016/j.atherosclerosis.2011.08.019
PMCID:
PMC3728428
AbstractArticlePDF–356K
18.
Screening for Coding Variants in FTO and SH2B1 Genes in Chinese Patients with Obesity
Zhaojing Zheng, Li Hong, Xiaodong Huang, Peirong Yang, Juan Li, Yu Ding, Ru-en Yao, Juan Geng, Yongnian Shen, Yiping Shen, Qihua Fu, Yongguo Yu
PLoS One. 2013; 8(6): e67039. Published online 2013 Jun 25. doi: 10.1371/journal.pone.0067039
PMCID:
PMC3692548
AbstractArticlePDF–587K
19.
Adapter Protein SH2B1β Binds Filamin A to Regulate Prolactin-Dependent Cytoskeletal Reorganization and Cell Motility
Leah Rider, Maria Diakonova
Mol Endocrinol. 2011 Jul; 25(7): 1231–1243. Published online 2011 May 12. doi: 10.1210/me.2011-0056
PMCID:
PMC3125092
AbstractArticle
20.
Neuronal SH2B1 is essential for controlling energy and glucose homeostasis
Decheng Ren, Yingjiang Zhou, David Morris, Minghua Li, Zhiqin Li, Liangyou Rui
J Clin Invest. 2007 Feb 1; 117(2): 397–406. Published online 2007 Jan 18. doi: 10.1172/JCI29417
PMCID:
PMC1765516
AbstractArticlePDF–1.3M

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