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Select item 53265571.

Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms

Mikaela D. Stewart, Emily D. Duncan, Ernesto Coronado, Paul A. DaRosa, Jonathan N. Pruneda, Peter S. Brzovic, Rachel E. Klevit

Protein Sci. 2017 Mar; 26(3): 475–483. Published online 2017 Jan 23. doi: 10.1002/pro.3091

PMCID:: PMC5326557

Abstract Article PDF–1.5M

Select item 26501142.

A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration

Jessie Chu, Nancy A. Hong, Claudio A. Masuda, Brian V. Jenkins, Keats A. Nelms, Christopher C. Goodnow, Richard J. Glynne, Hua Wu, Eliezer Masliah, Claudio A. P. Joazeiro, Steve A. Kay

Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7): 2097–2103. Published online 2009 Feb 5. doi: 10.1073/pnas.0812819106

PMCID:: PMC2650114

Abstract Article PDF–1.0M

Select item 44629363.

The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon

Karina von der Malsburg, Sichen Shao, Ramanujan S. Hegde

Mol Biol Cell. 2015 Jun 15; 26(12): 2168–2180. doi: 10.1091/mbc.E15-01-0040

PMCID:: PMC4462936

Abstract Article PDF–1.5M

Select item 29884964.

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

Mario H. Bengtson, Claudio A.P. Joazeiro

Nature. Author manuscript; available in PMC 2011 Mar 23.

Published in final edited form as: Nature. 2010 Sep 23; 467(7314): 470–473. Published online 2010 Sep 12. doi: 10.1038/nature09371

PMCID:: PMC2988496

Abstract Article PDF–1.2M

Select item 98434885.

Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling

Gongsheng Yuan, Shu-ting Yang, Shuying Yang

Mol Ther Nucleic Acids. 2023 Mar 14; 31: 197–210. Published online 2022 Dec 27. doi: 10.1016/j.omtn.2022.12.017

PMCID:: PMC9843488

Abstract Article PDF–4.7M

Select item 63440516.

Release of ubiquitinated and non-ubiquitinated nascent chains from stalled mammalian ribosomal complexes by ANKZF1 and Ptrh1

Kazushige Kuroha, Alexandra Zinoviev, Christopher U. T. Hellen, Tatyana V. Pestova

Mol Cell. Author manuscript; available in PMC 2019 Oct 18.

Published in final edited form as: Mol Cell. 2018 Oct 18; 72(2): 286–302.e8. Published online 2018 Sep 20. doi: 10.1016/j.molcel.2018.08.022

PMCID:: PMC6344051

Abstract Article PDF–1.1M

Select item 55344337.

Ubiquitination of stalled ribosome triggers ribosome-associated quality control

Yoshitaka Matsuo, Ken Ikeuchi, Yasushi Saeki, Shintaro Iwasaki, Christian Schmidt, Tsuyoshi Udagawa, Fumiya Sato, Hikaru Tsuchiya, Thomas Becker, Keiji Tanaka, Nicholas T. Ingolia, Roland Beckmann, Toshifumi Inada

Nat Commun. 2017; 8: 159. Published online 2017 Jul 31. doi: 10.1038/s41467-017-00188-1

PMCID:: PMC5534433

Abstract Article PDF–2.1M

Select item 54180448.

RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling

Ryan J. Malonis, Wenxiang Fu, Mark J. Jelcic, Marae Thompson, Brian S. Canter, Mary Tsikitis, Francisco J. Esteva, Irma Sánchez

J Biol Chem. 2017 May 5; 292(18): 7435–7451. Published online 2017 Mar 14. doi: 10.1074/jbc.M117.783662

PMCID:: PMC5418044

Abstract Article PDF–2.7M

Select item 100827719.

The role of RNF149 in the pre-emptive quality control substrate ubiquitination

Aster Legesse, Nathali Kaushansky, Ilana Braunstein, Haddas Saad, Gerardo Lederkremer, Ami Navon, Ariel Stanhill

Commun Biol. 2023; 6: 385. Published online 2023 Apr 8. doi: 10.1038/s42003-023-04763-9

PMCID:: PMC10082771

Abstract Article PDF–2.2M

Select item 432188110.

Structure and Assembly Pathway of the Ribosome Quality Control Complex

Sichen Shao, Alan Brown, Balaji Santhanam, Ramanujan S. Hegde

Mol Cell. 2015 Feb 5; 57(3): 433–444. doi: 10.1016/j.molcel.2014.12.015

PMCID:: PMC4321881

Abstract Article

Select item 419392211.

Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

Henrike C Besche, Zhe Sha, Nikolay V Kukushkin, Andreas Peth, Eva-Maria Hock, Woong Kim, Steven Gygi, Juan A Gutierrez, Hua Liao, Lawrence Dick, Alfred L Goldberg

EMBO J. 2014 May 16; 33(10): 1159–1176. Published online 2014 May 8. doi: 10.1002/embj.201386906

PMCID:: PMC4193922

Abstract Article PDF–1.1M

Select item 658469112.

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI

Wen-Feng Hu, Kimiko L. Krieger, Dragana Lagundžin, Xueli Li, Ronald S. Cheung, Toshiyasu Taniguchi, Keith R. Johnson, Tadayoshi Bessho, Alvaro N. A. Monteiro, Nicholas T. Woods

Cell Death Discov. 2019; 5: 105. Published online 2019 Jun 19. doi: 10.1038/s41420-019-0185-3

PMCID:: PMC6584691

Abstract Article PDF–1.6M

Select item 822574113.

Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network

Yu-Kun Xia, Yi-Rong Zeng, Meng-Li Zhang, Peng Liu, Fang Liu, Hao Zhang, Chen-Xi He, Yi-Ping Sun, Jin-Ye Zhang, Cheng Zhang, Lei Song, Chen Ding, Yu-Jie Tang, Zhen Yang, Chen Yang, Pu Wang, Kun-Liang Guan, Yue Xiong, Dan Ye

Protein Cell. 2021 Jul; 12(7): 557–577. Published online 2020 Jul 18. doi: 10.1007/s13238-020-00754-2

PMCID:: PMC8225741

Abstract Article PDF–3.1M

Select item 273665214.

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

Sjoerd J L van Wijk, Sjoerd J de Vries, Patrick Kemmeren, Anding Huang, Rolf Boelens, Alexandre M J J Bonvin, H Th Marc Timmers

Mol Syst Biol. 2009; 5: 295. Published online 2009 Aug 18. doi: 10.1038/msb.2009.55

Correction in:: Mol Syst Biol. 2009; 5: 317.

PMCID:: PMC2736652

Abstract Article PDF–5.6M

Select item 949339415.

Quantitative interactome proteomics identifies a proteostasis network for GABA_A receptors

Ya-Juan Wang, Xiao-Jing Di, Ting-Wei Mu

J Biol Chem. 2022 Oct; 298(10): 102423. Published online 2022 Aug 27. doi: 10.1016/j.jbc.2022.102423

PMCID:: PMC9493394

Abstract Article PDF–2.6M

Select item 694423816.

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion

Antoine Méant, Beichen Gao, Geneviève Lavoie, Sami Nourreddine, Flora Jung, Léo Aubert, Joseph Tcherkezian, Anne-Claude Gingras, Philippe P. Roux

Mol Cell Proteomics. 2020 Jan; 19(1): 50–64. Published online 2019 Nov 2. doi: 10.1074/mcp.RA119.001811

PMCID:: PMC6944238

Abstract Article PDF–5.7M

Select item 342034017.

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity

Oliver Stehling, Ajay A. Vashisht, Judita Mascarenhas, Zophonias O. Jonsson, Tanu Sharma, Daili J.A. Netz, Antonio J. Pierik, James A. Wohlschlegel, Roland Lill

Science. Author manuscript; available in PMC 2013 Jan 13.

Published in final edited form as: Science. 2012 Jul 13; 337(6091): 195–199. Published online 2012 Jun 7. doi: 10.1126/science.1219723

PMCID:: PMC3420340

Abstract Article PDF–1.8M

Select item 282753818.

A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks

Etsuko Miyamoto-Sato, Shigeo Fujimori, Masamichi Ishizaka, Naoya Hirai, Kazuyo Masuoka, Rintaro Saito, Yosuke Ozawa, Katsuya Hino, Takanori Washio, Masaru Tomita, Tatsuhiro Yamashita, Tomohiro Oshikubo, Hidetoshi Akasaka, Jun Sugiyama, Yasuo Matsumoto, Hiroshi Yanagawa

PLoS One. 2010; 5(2): e9289. Published online 2010 Feb 24. doi: 10.1371/journal.pone.0009289

PMCID:: PMC2827538

Abstract Article PDF–676K

Select item 796299419.

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Yanke Chen, Ting Jiang, Hongyi Zhang, Xingchun Gou, Cong Han, Jianhui Wang, Ann T. Chen, Jun Ma, Jun Liu, Zeming Chen, Xintao Jing, Hong Lei, Zhenzhen Wang, Youmei Bao, Mehdi Baqri, Yong Zhu, Ranjit S. Bindra, James E. Hansen, Jun Dou, Chen Huang, Jiangbing Zhou

Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Nat Cell Biol. 2020 Oct; 22(10): 1276–1285. Published online 2020 Oct 1. doi: 10.1038/s41556-020-00586-6