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Select item 108688261.

Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus

Daniela Bender, Alexandra Koulouri, Xingjian Wen, Mirco Glitscher, Anja Schollmeier, Liliana Fernandes da Costa, Robin Oliver Murra, Gert Paul Carra, Vanessa Haberger, Gerrit J. K. Praefcke, Eberhard Hildt

PLoS Pathog. 2024 Feb; 20(2): e1011976. Published online 2024 Feb 5. doi: 10.1371/journal.ppat.1011976

PMCID:: PMC10868826

Abstract Article PDF–5.5M

Select item 107631132.

Function and mechanism of GBP1 in the development and progression of cervical cancer

Senyu Wang, Yajing Zhang, Xiumin Ma, Yangchun Feng

J Transl Med. 2024; 22: 11. Published online 2024 Jan 2. doi: 10.1186/s12967-023-04837-6

PMCID:: PMC10763113

Abstract Article PDF–22M

Select item 106538073.

Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation

Antonia R. Bass, Marisa S. Egan, Jasmine Alexander-Floyd, Natasha Lopes Fischer, Jessica Doerner, Sunny Shin

mBio. 2023 Sep-Oct; 14(5): e01707-23. Published online 2023 Sep 22. doi: 10.1128/mbio.01707-23

PMCID:: PMC10653807

Abstract Article PDF–6.9M

Select item 102533934.

Human GBP1 Is Involved in the Repair of Damaged Phagosomes/Endolysosomes

Hellen Buijze, Volker Brinkmann, Robert Hurwitz, Anca Dorhoi, Stefan H. E. Kaufmann, Gang Pei

Int J Mol Sci. 2023 Jun; 24(11): 9701. Published online 2023 Jun 2. doi: 10.3390/ijms24119701

PMCID:: PMC10253393

Abstract Article PDF–8.9M

Select item 92470265.

Role of GBP1 in innate immunity and potential as a tuberculosis biomarker

Ting Shi, Linlin Huang, Yulin Zhou, Jianmei Tian

Sci Rep. 2022; 12: 11097. Published online 2022 Jun 30. doi: 10.1038/s41598-022-15482-2

PMCID:: PMC9247026

Abstract Article PDF–5.4M

Select item 84063206.

Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell Formation

Marisa Dilucca, Saray Ramos, Kateryna Shkarina, José Carlos Santos, Petr Broz

mBio. 2021 Jul-Aug; 12(4): e02054-21. Published online 2021 Aug 17. doi: 10.1128/mBio.02054-21

Correction in:: mBio. 2023 May-Jun; 14(3): e00694-23.

PMCID:: PMC8406320

Abstract Article PDF–5.9M

Select item 80687597.

The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri

Miriam Kutsch, Coral González-Prieto, Cammie F Lesser, Jörn Coers

Pathog Dis. 2021 Jul; 79(5): ftab023. Published online 2021 Apr 22. doi: 10.1093/femspd/ftab023

PMCID:: PMC8068759

Abstract Article PDF–3.7M

Select item 78915038.

Guanylate‐binding protein 1 correlates with advanced tumor features, and serves as a prognostic biomarker for worse survival in lung adenocarcinoma patients

Quanchao Wan, Jingming Qu, Longfei Li, Feng Gao

J Clin Lab Anal. 2021 Feb; 35(2): e23610. Published online 2020 Dec 10. doi: 10.1002/jcla.23610

PMCID:: PMC7891503

Abstract Article PDF–870K

Select item 74356959.

Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death

Daniel Fisch, Barbara Clough, Marie-Charlotte Domart, Vesela Encheva, Hironori Bando, Ambrosius P. Snijders, Lucy M. Collinson, Masahiro Yamamoto, Avinash R. Shenoy, Eva-Maria Frickel

Cell Rep. 2020 Aug 11; 32(6): 108008. Published online 2020 Aug 11. doi: 10.1016/j.celrep.2020.108008

PMCID:: PMC7435695

Abstract Article

Select item 597892910.

T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression

Dana A. M. Mustafa, Rute M. S. M. Pedrosa, Marcel Smid, Marcel van der Weiden, Vanja de Weerd, Alex L. Nigg, Cor Berrevoets, Lona Zeneyedpour, Neibla Priego, Manuel Valiente, Theo M. Luider, Reno Debets, John W. M. Martens, John A. Foekens, Anieta M. Sieuwerts, Johan M. Kros

Acta Neuropathol. 2018; 135(4): 581–599. Published online 2018 Jan 19. doi: 10.1007/s00401-018-1806-2

PMCID:: PMC5978929

Abstract Article PDF–9.5M

Select item 577356211.

Guanylate Binding Protein 1 Inhibits Osteogenic Differentiation of Human Mesenchymal Stromal Cells Derived from Bone Marrow

Shi Bai, Zhixiang Mu, Yuanding Huang, Ping Ji

Sci Rep. 2018; 8: 1048. Published online 2018 Jan 18. doi: 10.1038/s41598-018-19401-2

PMCID:: PMC5773562

Abstract Article PDF–1.3M

Select item 572741612.

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility

Anthony S. Piro, Dulcemaria Hernandez, Sarah Luoma, Eric M. Feeley, Ryan Finethy, Azeb Yirga, Eva M. Frickel, Cammie F. Lesser, Jörn Coers

mBio. 2017 Nov-Dec; 8(6): e01979-17. Published online 2017 Dec 12. doi: 10.1128/mBio.01979-17

PMCID:: PMC5727416

Abstract Article PDF–3.5M

Select item 551470813.

Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1

Sergii Shydlovskyi, Anke Y. Zienert, Semra Ince, Christine Dovengerds, Annika Hohendahl, Julia M. Dargazanli, Ailisa Blum, Saskia D. Günther, Nikolay Kladt, Michael Stürzl, Astrid C. Schauss, Miriam Kutsch, Aurélien Roux, Gerrit J. K. Praefcke, Christian Herrmann

Proc Natl Acad Sci U S A. 2017 Jul 11; 114(28): E5559–E5568. Published online 2017 Jun 23. doi: 10.1073/pnas.1620959114

PMCID:: PMC5514708

Abstract Article PDF–1.8M

Select item 530743914.

Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii

Aiping Qin, De-Hua Lai, Qifa Liu, Weijun Huang, Ya-Ping Wu, Xiaoyong Chen, Sunxing Yan, Huimin Xia, Geoff Hide, Zhao-Rong Lun, Francisco J. Ayala, Andy Peng Xiang

Proc Natl Acad Sci U S A. 2017 Feb 7; 114(6): 1365–1370. Published online 2017 Jan 25. doi: 10.1073/pnas.1619665114

PMCID:: PMC5307439

Abstract Article PDF–1.3M

Select item 503018815.

Guanylate-Binding Protein-1 protects ovarian cancer cell lines but not breast cancer cell lines from killing by paclitaxel

Aaron R. Tipton, Geoffrey O. Nyabuto, Jill A. Trendel, Travis M. Mazur, John P. Wilson, Suzan Wadi, Jacob S. Justinger, Garret L. Moore, Peter T. Nguyen, Deborah J. Vestal

Biochem Biophys Res Commun. Author manuscript; available in PMC 2017 Sep 30.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Sep 30; 478(4): 1617–1623. Published online 2016 Aug 31. doi: 10.1016/j.bbrc.2016.08.169

PMCID:: PMC5030188

Abstract Article PDF–1.9M

Select item 496161816.

Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii

Ashleigh C. Johnston, Anthony Piro, Barbara Clough, Malvin Siew, Sebastian Virreira Winter, Jörn Coers, Eva‐Maria Frickel

Cell Microbiol. 2016 Aug; 18(8): 1056–1064. Published online 2016 Mar 10. doi: 10.1111/cmi.12579

PMCID:: PMC4961618

Abstract Article PDF–680K

Select item 446235217.

Guanine nucleotide-binding protein 1 is one of the key molecules contributing to cancer cell radioresistance

Motoi Fukumoto, Tatsuya Amanuma, Yoshikazu Kuwahara, Tsutomu Shimura, Masatoshi Suzuki, Shiro Mori, Hiroyuki Kumamoto, Yohei Saito, Yasuhito Ohkubo, Zhenfeng Duan, Kenji Sano, Tomohiro Oguchi, Kazuyuki Kainuma, Shinichi Usami, Kengo Kinoshita, Inchul Lee, Manabu Fukumoto

Cancer Sci. 2014 Oct; 105(10): 1351–1359. Published online 2014 Sep 29. doi: 10.1111/cas.12489

PMCID:: PMC4462352

Abstract Article PDF–1.6M

Select item 391128718.

Gamma Interferon-Induced Guanylate Binding Protein 1 Is a Novel Actin Cytoskeleton Remodeling Factor

Nicole Ostler, Nathalie Britzen-Laurent, Andrea Liebl, Elisabeth Naschberger, Günter Lochnit, Markus Ostler, Florian Forster, Peter Kunzelmann, Semra Ince, Verena Supper, Gerrit J. K. Praefcke, Dirk W. Schubert, Hannes Stockinger, Christian Herrmann, Michael Stürzl

Mol Cell Biol. 2014 Jan; 34(2): 196–209. doi: 10.1128/MCB.00664-13

PMCID:: PMC3911287

Abstract Article PDF–4.3M

Select item 382320219.

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases

Matthias Hammon, Martin Herrmann, Oliver Bleiziffer, Galyna Pryymachuk, Laura Andreoli, Luis E Munoz, Kerstin U Amann, Michele Mondini, Marisa Gariglio, Paolo Airó, Vera S Schellerer, Antonis K Hatzopoulos, Raymund E Horch, Ulrich Kneser, Michael Stürzl, Elisabeth Naschberger

J Cell Mol Med. 2011 Jul; 15(7): 1582–1592. Published online 2011 Jun 22. doi: 10.1111/j.1582-4934.2010.01146.x