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Items: 1 to 20 of 55

1.
Targeted Overexpression of TGF-α in the Corneal Epithelium of Adult Transgenic Mice Induces Changes in Anterior Segment Morphology and Activates Noncanonical Wnt Signaling
Yong Yuan, Lung-Kun Yeh, Hongshan Liu, Osamu Yamanaka, William D. Hardie, Winston W.-Y. Kao, Chia-Yang Liu
Invest Ophthalmol Vis Sci. 2013 Mar; 54(3): 1829–1837. Published online 2013 Mar 11. doi: 10.1167/iovs.12-11477
PMCID:
PMC3626521
AbstractArticlePDF–511K
2.
KLF4 Regulates Corneal Epithelial Cell Cycle Progression by Suppressing Canonical TGF-β Signaling and Upregulating CDK Inhibitors P16 and P27
Anil Tiwari, Sudha Swamynathan, Nicholas Alexander, John Gnalian, Shenghe Tian, Paul R. Kinchington, Shivalingappa K. Swamynathan
Invest Ophthalmol Vis Sci. 2019 Feb; 60(2): 731–740. doi: 10.1167/iovs.18-26423
PMCID:
PMC6383833
AbstractArticlePDF–3.6M
3.
KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial–Mesenchymal Transition
Anil Tiwari, Chelsea L. Loughner, Sudha Swamynathan, Shivalingappa K. Swamynathan
Invest Ophthalmol Vis Sci. 2017 May; 58(5): 2785–2795. doi: 10.1167/iovs.17-21826
PMCID:
PMC5455171
AbstractArticlePDF–3.6M
4.
Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy
Edwin H.A. Allen, David G. Courtney, Sarah D. Atkinson, Johnny E. Moore, Laura Mairs, Ebbe Toftgaard Poulsen, Davide Schiroli, Eleonora Maurizi, Christian Cole, Robyn P. Hickerson, John James, Helen Murgatroyd, Frances J.D. Smith, Carrie MacEwen, Jan J. Enghild, M. Andrew Nesbit, Deena M. Leslie Pedrioli, W.H. Irwin McLean, C.B. Tara Moore
Hum Mol Genet. 2016 Mar 15; 25(6): 1176–1191. Published online 2016 Jan 11. doi: 10.1093/hmg/ddw001
PMCID:
PMC4764196
AbstractArticlePDF–1.1M
5.
Spatiotemporally Regulated Ablation of Klf4 in Adult Mouse Corneal Epithelial Cells Results in Altered Epithelial Cell Identity and Disrupted Homeostasis
Emili E. Delp, Sudha Swamynathan, Winston W. Kao, Shivalingappa K. Swamynathan
Invest Ophthalmol Vis Sci. 2015 Jun; 56(6): 3549–3558. Published online 2015 Jun 3. doi: 10.1167/iovs.15-16463
PMCID:
PMC4464104
AbstractArticlePDF–2.9M
6.
Crosstalk between TGF-β and MAPK Signaling during Corneal Wound Healing
Kazuto Terai, Mindy K. Call, Hongshan Liu, Shizuya Saika, Chia-Yang Liu, Yasuhito Hayashi, Tai-Ichiro Chikama, Jianhua Zhang, Noriko Terai, Candace W.-C. Kao, Winston W.-Y. Kao
Invest Ophthalmol Vis Sci. 2011 Oct; 52(11): 8208–8215. Published online 2011 Oct 17. doi: 10.1167/iovs.11-8017
PMCID:
PMC3208026
AbstractArticlePDF–2.2M
7.
IκB Kinase β Regulates Epithelium Migration during Corneal Wound Healing
Liang Chen, Qinghang Meng, Winston Kao, Ying Xia
PLoS One. 2011; 6(1): e16132. Published online 2011 Jan 17. doi: 10.1371/journal.pone.0016132
PMCID:
PMC3022035
AbstractArticlePDF–911K
8.
Monoallelic Expression of Krt12 Gene during Corneal-type Epithelium Differentiation of Limbal Stem Cells
Yasuhito Hayashi, Mindy K. Call, Chia-Yang Liu, Miyuki Hayashi, George Babcock, Yuichi Ohashi, Winston W.-Y. Kao
Invest Ophthalmol Vis Sci. 2010 Sep; 51(9): 4562–4568. doi: 10.1167/iovs.10-5331
PMCID:
PMC2941181
AbstractArticlePDF–1.9M
9.
Excess FGF-7 in Corneal Epithelium Causes Corneal Intraepithelial Neoplasia in Young Mice and Epithelium Hyperplasia in Adult Mice
Taiichiro Chikama, Chia-Yang Liu, Johanna T.A. Meij, Yasuhito Hayashi, I-Jong Wang, Liu Yang, Teruo Nishida, Winston W.Y. Kao
Am J Pathol. 2008 Mar; 172(3): 638–649. doi: 10.2353/ajpath.2008.070897
PMCID:
PMC2258268
AbstractArticlePDF–3.5M
10.
Sirt1 Regulates Corneal Epithelial Migration by Deacetylating Cortactin
Yong Lin, Qi Liu, Li Li, Rusen Yang, Juxiu Ye, Shuai Yang, Guangying Luo, Peter S. Reinach, Dongsheng Yan
Invest Ophthalmol Vis Sci. 2022 Nov; 63(12): 14. Published online 2022 Nov 9. doi: 10.1167/iovs.63.12.14
PMCID:
PMC9652720
AbstractArticlePDF–5.6M
11.
Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas
Chelsea L. Loughner, Anil Tiwari, Doreswamy Kenchegowda, Sudha Swamynathan, Shivalingappa K. Swamynathan
Invest Ophthalmol Vis Sci. 2017 Sep; 58(11): 4683–4693. doi: 10.1167/iovs.17-22498
PMCID:
PMC5598321
AbstractArticlePDF–3.0M
12.
Study of corneal epithelial progenitor origin and the Yap1 requirement using keratin 12 lineage tracing transgenic mice
Ramesh Babu Kasetti, Subhash Gaddipati, Shifu Tian, Lei Xue, Winston W.-Y. Kao, Qingxian Lu, Qiutang Li
Sci Rep. 2016; 6: 35202. Published online 2016 Oct 13. doi: 10.1038/srep35202
PMCID:
PMC5062132
AbstractArticlePDF–1.5M
13.
Corneal Expression of SLURP-1 by Age, Sex, Genetic Strain, and Ocular Surface Health
Sudha Swamynathan, Emili E. Delp, Stephen A. K. Harvey, Chelsea L. Loughner, Leela Raju, Shivalingappa K. Swamynathan
Invest Ophthalmol Vis Sci. 2015 Dec; 56(13): 7888–7896. Published online 2015 Dec 15. doi: 10.1167/iovs.15-18206
PMCID:
PMC4682604
AbstractArticlePDF–2.3M
14.
Serum response factor: positive and negative regulation of an epithelial gene expression network in the destrin mutant cornea
Sharolyn V. Kawakami-Schulz, Angela M. Verdoni, Shannon G. Sattler, Erik Jessen, Winston W.-Y. Kao, Akihiro Ikeda, Sakae Ikeda
Physiol Genomics. 2014 Apr 15; 46(8): 277–289. Published online 2014 Feb 18. doi: 10.1152/physiolgenomics.00126.2013
PMCID:
PMC4035658
AbstractArticle
15.
A Pathogenic Relationship Between a Regulator of the Actin Cytoskeleton and Serum Response Factor
Angela M. Verdoni, Keaton J. Schuster, Brian S. Cole, Akihiro Ikeda, Winston W. Kao, Sakae Ikeda
Genetics. 2010 Sep; 186(1): 147–157. doi: 10.1534/genetics.110.117309
PMCID:
PMC2940283
AbstractArticlePDF–3.0M
16.
Conditional Deletion of Cited2 Results in Defective Corneal Epithelial Morphogenesis and Maintenance
Yu Chen, Eric C Carlson, Zhi-Yi Chen, Anne Hamik, Mukesh K Jain, Sally L. Dunwoodie, Yu-Chung Yang
Dev Biol. Author manuscript; available in PMC 2010 Oct 1.
Published in final edited form as: Dev Biol. 2009 Oct 1; 334(1): 243–252. Published online 2009 Jul 24. doi: 10.1016/j.ydbio.2009.07.028
PMCID:
PMC2752849
AbstractArticlePDF–1023K
17.
Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice
Daniel Y. Weng, Yujin Zhang, Yasuhito Hayashi, Chia-Yi Kuan, Chia-Yang Liu, George Babcock, Wei-Lan Weng, Sandy Schwemberger, Winston W.-Y. Kao
Mol Vis. 2008; 14: 562–571. Published online 2008 Mar 20.
PMCID:
PMC2274927
AbstractArticlePDF–2.5M
18.
Disruption of eyelid and cornea morphogenesis by epithelial β-catenin gain-of-function
Shin Mizoguchi, Kentaro Suzuki, Jianhua Zhang, Osamu Yamanaka, Chia-Yang Liu, Yuka Okada, Masayasu Miyajima, Masahide Kokado, WinstonWY Kao, Gen Yamada, Shizuya Saika
Mol Vis. 2015; 21: 793–803. Published online 2015 Jul 31.
PMCID:
PMC4522241
AbstractArticlePDF–1.9M
19.
Gene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid Morphogenesis
Maureen Mongan, Qinghang Meng, Jingjing Wang, Winston W.-Y. Kao, Alvaro Puga, Ying Xia
J Biol Chem. 2015 Aug 7; 290(32): 19770–19779. Published online 2015 Jun 24. doi: 10.1074/jbc.M115.665729
PMCID:
PMC4528138
AbstractArticlePDF–1.9M
20.
14-3-3σ Controls Corneal Epithelium Homeostasis and Wound Healing
Qingxian Lu, Ying Xin, Fei Ye, Gary Foulks, Qiutang Li
Invest Ophthalmol Vis Sci. 2011 Apr; 52(5): 2389–2396. Published online 2011 Apr 14. doi: 10.1167/iovs.09-4981
PMCID:
PMC3081250
AbstractArticlePDF–2.7M

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