PMC Links for Gene (Select 2769) - PMC

Select item 38000351.

Heterotrimeric G-Protein, G_α16, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer

Sreedevi Avasarala, Rama Kamesh Bikkavilli, Michelle Van Scoyk, Wei Zhang, Ajibike Lapite, Logan Hostetter, Joshua T. Byers, Lynn E. Heasley, Jang Won Sohn, Robert A. Winn

PLoS One. 2013; 8(10): e76895. Published online 2013 Oct 18. doi: 10.1371/journal.pone.0076895

PMCID:: PMC3800035

Abstract Article PDF–2.3M

Select item 32866412.

Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq

Richard T. Waldron, Giulio Innamorati, M. Eugenia Torres-Marquez, James Sinnett-Smith, Enrique Rozengurt

Cell Signal. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: Cell Signal. 2012 Apr; 24(4): 914–921. Published online 2011 Dec 29. doi: 10.1016/j.cellsig.2011.12.014

PMCID:: PMC3286641

Abstract Article PDF–2.1M

Select item 519223.

G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells.

T T Amatruda, 3rd, D A Steele, V Z Slepak, M I Simon

Proc Natl Acad Sci U S A. 1991 Jul 1; 88(13): 5587–5591. doi: 10.1073/pnas.88.13.5587

PMCID:: PMC51922

Summary Page Browse PDF–1.2M

Select item 475254.

Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.

T Kozasa, J R Hepler, A V Smrcka, M I Simon, S G Rhee, P C Sternweis, A G Gilman

Proc Natl Acad Sci U S A. 1993 Oct 1; 90(19): 9176–9180. doi: 10.1073/pnas.90.19.9176

PMCID:: PMC47525

Summary Page Browse PDF–1.1M

Select item 30981435.

Gα₁₆interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling

Andrew MF Liu, Rico KH Lo, Emily X Guo, Maurice KC Ho, Richard D Ye, Yung H Wong

BMC Struct Biol. 2011; 11: 17. Published online 2011 Apr 13. doi: 10.1186/1472-6807-11-17

PMCID:: PMC3098143

Abstract Article PDF–10M

Select item 12197466.

Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits.

R Gaudreau, C Le Gouill, S Métaoui, S Lemire, J Stankovà, M Rola-Pleszczynski

Biochem J. 1998 Oct 1; 335(Pt 1): 15–18. doi: 10.1042/bj3350015

PMCID:: PMC1219746

Summary PDF–244K

Select item 1552067.

Identification of Tetratricopeptide Repeat 1 as an Adaptor Protein That Interacts with Heterotrimeric G Proteins and the Small GTPase Ras

Caroline Marty, Darren D. Browning, Richard D. Ye

Mol Cell Biol. 2003 Jun; 23(11): 3847–3858. doi: 10.1128/MCB.23.11.3847-3858.2003

PMCID:: PMC155206

Abstract Article PDF–631K

Select item 30256958.

The Association of Genome-Wide Variation with the Risk of Incident Heart Failure in Adults of European and African Ancestry: A Prospective Meta-Analysis from the CHARGE Consortium

Nicholas L. Smith, Janine F. Felix, Alanna C. Morrison, Serkalem Demissie, Nicole L. Glazer, Laura R. Loehr, L. Adrienne Cupples, Abbas Dehghan, Thomas Lumley, Wayne D. Rosamond, Wolfgang Lieb, Fernando Rivadeneira, Joshua C. Bis, Aaron R. Folsom, Emelia Benjamin, Yurii S. Aulchenko, Talin Haritunians, David Couper, Joanne Murabito, Ying A. Wang, Bruno H. Stricker, John S. Gottdiener, Patricia P. Chang, Thomas J. Wang, Kenneth M. Rice, Albert Hofman, Susan R. Heckbert, Ervin R. Fox, Christopher J. O’Donnell, Andre G. Uitterlinden, Jerome I. Rotter, James T. Willerson, Daniel Levy, Cornelia M. van Duijn, Bruce M. Psaty, Jacqueline C. M. Witteman, Eric Boerwinkle, Ramachandran S. Vasan

Circ Cardiovasc Genet. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2010 Jun 1; 3(3): 256–266. Published online 2010 May 5. doi: 10.1161/CIRCGENETICS.109.895763

PMCID:: PMC3025695

Abstract Article PDF–602K

Select item 449109.

Mechanism of GTP hydrolysis by G-protein alpha subunits.

C Kleuss, A S Raw, E Lee, S R Sprang, A G Gilman

Proc Natl Acad Sci U S A. 1994 Oct 11; 91(21): 9828–9831. doi: 10.1073/pnas.91.21.9828

PMCID:: PMC44910

Summary Page Browse PDF–925K

Select item 298423810.

Systematic Mapping and Functional Analysis of a Family of Human Epididymal Secretory Sperm-Located Proteins

JianYuan Li, FuJun Liu, HaiYan Wang, Xin Liu, Juan Liu, Ning Li, FengChun Wan, WenTing Wang, ChengLin Zhang, ShaoHua Jin, Jie Liu, Peng Zhu, YunXiang Liu

Mol Cell Proteomics. 2010 Nov; 9(11): 2517–2528. doi: 10.1074/mcp.M110.001719

PMCID:: PMC2984238

Abstract Article PDF–479K

Select item 973393711.

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos

Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437

PMCID:: PMC9733937

Abstract Article PDF–2.2M

Select item 464794112.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 319082613.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011