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Select item 99955031.

ARHGAP35 is a novel factor disrupted in human developmental eye phenotypes

Linda M. Reis, Nicolas Chassaing, Tanya Bardakjian, Samuel Thompson, Adele Schneider, Elena V. Semina

Eur J Hum Genet. 2023 Mar; 31(3): 363–367. Published online 2022 Dec 1. doi: 10.1038/s41431-022-01246-z

PMCID:: PMC9995503

Abstract Article PDF–878K

Select item 98409782.

Identification of an inhibitory domain in GTPase-activating protein p190RhoGAP responsible for masking its functional GAP domain

Capucine Héraud, Mathilde Pinault, Véronique Neaud, Frédéric Saltel, Valérie Lagrée, Violaine Moreau

J Biol Chem. 2023 Jan; 299(1): 102792. Published online 2022 Dec 11. doi: 10.1016/j.jbc.2022.102792

PMCID:: PMC9840978

Abstract Article PDF–5.6M

Select item 93422883.

Rho GTPase-activating protein 35 suppresses gastric cancer metastasis by regulating cytoskeleton reorganization and epithelial-to-mesenchymal transition

Yi Sun, Rui Du, Yulong Shang, Changhao Liu, Linhua Zheng, Ruiqing Sun, Yuanyong Wang, Guofang Lu

Bioengineered. 2022; 13(6): 14605–14615. Published online 2022 Jun 26. doi: 10.1080/21655979.2022.2092677

PMCID:: PMC9342288

Abstract Article PDF–7.3M

Select item 61229984.

p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity

Scott R. Frank, Clemens P. Köllmann, Phi Luong, Giorgio G. Galli, Lihua Zou, André Bernards, Gad Getz, Raffaele A. Calogero, Morten Frödin, Steen H. Hansen

J Cell Biol. 2018 Sep 3; 217(9): 3183–3201. doi: 10.1083/jcb.201710058

Correction in:: J Cell Biol. 2018 Sep 3; 217(9): 3313.

PMCID:: PMC6122998

Abstract Article PDF–3.6M

Select item 60826895.

P190RhoGAP prevents mitotic spindle fragmentation and is required to activate Aurora A kinase at acentriolar poles

Arkadi Manukyan, Lilit Sargsyan, Sarah J. Parsons, P. Todd Stukenberg

Chromosoma. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Chromosoma. 2018 Sep; 127(3): 375–386. Published online 2018 Apr 14. doi: 10.1007/s00412-018-0670-0

PMCID:: PMC6082689

Abstract Article PDF–959K

Select item 41248506.

Rho GTPase-Activating Protein 35 rs1052667 Polymorphism and Osteosarcoma Risk and Prognosis

Jinmin Zhao, Hua Xu, Maolin He, Zhe Wang, Yang Wu

Biomed Res Int. 2014; 2014: 396947. Published online 2014 Jul 20. doi: 10.1155/2014/396947

PMCID:: PMC4124850

Abstract Article PDF–692K

Select item 29306927.

Mitotic Down-regulation of p190RhoGAP Is Required for the Successful Completion of Cytokinesis

Sergio A. Sánchez Manchinelly, Joyce Agati Miller, Ling Su, Tsuyoshi Miyake, Lisa Palmer, Masahito Mikawa, Sarah J. Parsons

J Biol Chem. 2010 Aug 27; 285(35): 26923–26932. Published online 2010 Jun 9. doi: 10.1074/jbc.M110.103804

PMCID:: PMC2930692

Abstract Article PDF–1.7M

Select item 74262648.

p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth

Hanyue Ouyang, Phi Luong, Morten Frödin, Steen H. Hansen

Oncogene. 2020; 39(33): 5570–5587. Published online 2020 Jul 8. doi: 10.1038/s41388-020-1385-2

PMCID:: PMC7426264

Abstract Article PDF–5.8M

Select item 67562369.

Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation

Daici Chen, Yichen Li, Xiaowen Zhang, Haiyong Wu, Qian Wang, Jian Cai, Yanmei Cui, Huanliang Liu, Ping Lan, Jianping Wang, Zihuan Yang, Lei Wang

Oncogene. 2019; 38(37): 6429–6444. Published online 2019 Jul 22. doi: 10.1038/s41388-019-0891-6

PMCID:: PMC6756236

Abstract Article PDF–5.6M

Select item 531416610.

Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis

Prasanna Parasuraman, Peter Mulligan, James A. Walker, Bihua Li, Myriam Boukhali, Wilhelm Haas, Andre Bernards

J Biol Chem. 2017 Feb 17; 292(7): 2679–2689. Published online 2016 Dec 22. doi: 10.1074/jbc.M116.769216

PMCID:: PMC5314166

Abstract Article PDF–1.6M

Select item 399355111.

The Human Papillomavirus E7 Proteins Associate with p190RhoGAP and Alter Its Function

Biljana Todorovic, Anthony C. Nichols, Jennifer M. Chitilian, Michael P. Myers, Trevor G. Shepherd, Sarah J. Parsons, John W. Barrett, Lawrence Banks, Joe S. Mymryk

J Virol. 2014 Apr; 88(7): 3653–3663. doi: 10.1128/JVI.03263-13

PMCID:: PMC3993551

Abstract Article PDF–2.4M

Select item 389762212.

p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line

Shawna L. Organ, Josephine Hai, Nikolina Radulovich, Christopher B. Marshall, Lisa Leung, Takehiko Sasazuki, Senji Shirasawa, Chang-Qi Zhu, Roya Navab, Mitsuhiko Ikura, Ming-Sound Tsao

PLoS One. 2014; 9(1): e86103. Published online 2014 Jan 21. doi: 10.1371/journal.pone.0086103

PMCID:: PMC3897622

Abstract Article PDF–1.9M

Select item 366772213.

RhoA is down-regulated at cell–cell contacts via p190RhoGAP-B in response to tensional homeostasis

Suzanne M. Ponik, Steven M. Trier, Michele A. Wozniak, Kevin W. Eliceiri, Patricia J. Keely

Mol Biol Cell. 2013 Jun 1; 24(11): 1688–1699. doi: 10.1091/mbc.E12-05-0386

PMCID:: PMC3667722

Abstract Article PDF–1.4M

Select item 279140114.

Opposing Roles of p190RhoGAP and Ect2 RhoGEF in Regulating Cytokinesis

Masahito Mikawa, Ling Su, Sarah J. Parsons

Cell Cycle. Author manuscript; available in PMC 2009 Dec 10.

Published in final edited form as: Cell Cycle. 2008 Jul 1; 7(13): 2003–2012. doi: 10.4161/cc.7.13.6128

PMCID:: PMC2791401

Abstract Article PDF–1.2M

Select item 273988315.

Regulation of the substrate preference of p190RhoGAP by PKC–mediated phosphorylation of a phospholipid binding site

Magdolna Lévay, Jeffrey Settleman, Erzsébet Ligeti

Biochemistry. Author manuscript; available in PMC 2010 Sep 15.

Published in final edited form as: Biochemistry. 2009 Sep 15; 48(36): 8615–8623. doi: 10.1021/bi900667y

PMCID:: PMC2739883

Abstract Article PDF–802K

Select item 252912616.

Inadequate Activation of the GTPase RhoA Contributes to the Lack of Fibronectin Matrix Assembly in von Hippel-Lindau Protein-defective Renal Cancer Cells

Monica Feijóo-Cuaresma, Fernando Méndez, Alfredo Maqueda, Miguel A. Esteban, Salvador Naranjo-Suarez, Maria C. Castellanos, Mercedes Hernández del Cerro, Silvia N. Vazquez, Angeles García-Pardo, Manuel O. Landázuri, Maria J. Calzada

J Biol Chem. 2008 Sep 5; 283(36): 24982–24990. doi: 10.1074/jbc.M709390200