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Select item 110431071.

Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain

Simona Denaro, Lorella Pasquinucci, Rita Turnaturi, Cristiana Alberghina, Lucia Longhitano, Sebastiano Giallongo, Giuliana Costanzo, Salvatore Spoto, Margherita Grasso, Agata Zappalà, Giovanni Li Volti, Daniele Tibullo, Nunzio Vicario, Rosalba Parenti, Carmela Parenti

Mol Neurobiol. 2024; 61(5): 2672–2685. Published online 2023 Nov 3. doi: 10.1007/s12035-023-03717-w

PMCID:: PMC11043107

Abstract Article PDF–3.4M

Select item 93471742.

Activation of the sigma-1 receptor exerts cardioprotection in a rodent model of chronic heart failure by stimulation of angiogenesis

Xin Zhao, Xin Liu, Xiuhuan Chen, Xueyu Han, Yazhou Sun, Yuhong Fo, Xiukun Wang, Chuan Qu, Bo Yang

Mol Med. 2022; 28: 87. Published online 2022 Aug 3. doi: 10.1186/s10020-022-00517-1

PMCID:: PMC9347174

Abstract Article PDF–2.6M

Select item 91221063.

Effect of sigma-1 receptor antagonism on ethanol and natural reward seeking

R. Martin-Fardon, E. M. Strong, F. Weiss

Neuroreport. Author manuscript; available in PMC 2022 May 20.

Published in final edited form as: Neuroreport. 2012 Oct 3; 23(14): 809–813. doi: 10.1097/WNR.0b013e32835717c8

PMCID:: PMC9122106

Abstract Article PDF–410K

Select item 81287474.

Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain

Shao-Ming Wang, Nino Goguadze, Yuriko Kimura, Yuko Yasui, Bin Pan, Tzu-Yun Wang, Yoki Nakamura, Yu-Ting Lin, Quinn H. Hogan, Katherine L. Wilson, Tsung-Ping Su, Hsiang-en Wu

Mol Neurobiol. 2021; 58(6): 2523–2541. Published online 2021 Jan 18. doi: 10.1007/s12035-020-02276-8

Correction in:: Mol Neurobiol. 2021; 58(6): 2542.

PMCID:: PMC8128747

Abstract Article PDF–3.7M

Select item 76719475.

Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain

Seung Min Shin, Fei Wang, Chensheng Qiu, Brandon Itson-Zoske, Quinn H. Hogan, Hongwei Yu

Gene Ther. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Gene Ther. 2022 Feb; 29(1-2): 1–15. Published online 2020 May 18. doi: 10.1038/s41434-020-0157-5

PMCID:: PMC7671947

Abstract Article PDF–2.3M

Select item 62612716.

Structural basis for σ₁ receptor ligand recognition

Hayden R. Schmidt, Robin M. Betz, Ron O. Dror, Andrew C. Kruse

Nat Struct Mol Biol. Author manuscript; available in PMC 2019 Apr 5.

Published in final edited form as: Nat Struct Mol Biol. 2018 Oct; 25(10): 981–987. Published online 2018 Oct 5. doi: 10.1038/s41594-018-0137-2

PMCID:: PMC6261271

Abstract Article PDF–812K

Select item 44240677.

Sigma-1 Receptor Mediates Acquisition of Alcohol Drinking and Seeking behavior in Alcohol-Preferring Rats

Angelo Blasio, Marta Valenza, Malliga R. Iyer, Kenner C. Rice, Luca Steardo, T. Hayashi, Pietro Cottone, Valentina Sabino

Behav Brain Res. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Behav Brain Res. 2015 Jul 1; 287: 315–322. Published online 2015 Apr 4. doi: 10.1016/j.bbr.2015.03.065

PMCID:: PMC4424067

Abstract Article PDF–886K

Select item 38476298.

Sigma-1 receptor expression in sensory neurons and the effect of painful peripheral nerve injury

Madhavi L Bangaru, Dorothee Weihrauch, Qing-Bo Tang, Vasiliki Zoga, Quinn Hogan, Hsiang-en Wu

Mol Pain. 2013; 9: 47. Published online 2013 Sep 10. doi: 10.1186/1744-8069-9-47

PMCID:: PMC3847629

Abstract Article PDF–1.9M

Select item 37059619.

Insights into the Sigma-1 receptor chaperone’s cellular functions: a microarray report

Shang-Yi Tsai, Richard Kyle Rothman, Tsung-Ping Su

Synapse. Author manuscript; available in PMC 2013 Jul 9.

Published in final edited form as: Synapse. 2012 Jan; 66(1): 42–51. Published online 2011 Oct 11. doi: 10.1002/syn.20984

PMCID:: PMC3705961

Abstract Article PDF–740K

Select item 352230910.

The Lifetime of UDP-galactose:Ceramide Galactosyltransferase Is Controlled by a Distinct Endoplasmic Reticulum-associated Degradation (ERAD) Regulated by Sigma-1 Receptor Chaperones

Teruo Hayashi, Eri Hayashi, Michiko Fujimoto, Hein Sprong, Tsung-Ping Su

J Biol Chem. 2012 Dec 14; 287(51): 43156–43169. Published online 2012 Oct 26. doi: 10.1074/jbc.M112.380444

PMCID:: PMC3522309

Abstract Article PDF–3.9M

Select item 308350311.

Ethanol exposure in early adolescence inhibits intrinsic neuronal plasticity via sigma-1 receptor activation in hippocampal CA1 neurons

Jilla Sabeti

Alcohol Clin Exp Res. Author manuscript; available in PMC 2012 May 1.

Published in final edited form as: Alcohol Clin Exp Res. 2011 May; 35(5): 885–904. Published online 2011 Feb 11. doi: 10.1111/j.1530-0277.2010.01419.x

PMCID:: PMC3083503

Abstract Article PDF–930K

Select item 307932012.

Activation of σ-Receptors Induces Binge-like Drinking in Sardinian Alcohol-Preferring Rats

Valentina Sabino, Pietro Cottone, Angelo Blasio, Malliga R Iyer, Luca Steardo, Kenner C Rice, Bruno Conti, George F Koob, Eric P Zorrilla

Neuropsychopharmacology. 2011 May; 36(6): 1207–1218. Published online 2011 Feb 23. doi: 10.1038/npp.2011.5

PMCID:: PMC3079320

Abstract Article PDF–563K

Select item 266969413.

The sigma receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

Valentina Sabino, Pietro Cottone, Yu Zhao, Malliga R. Iyer, Luca Steardo, Jr, Luca Steardo, Kenner C. Rice, Bruno Conti, George F. Koob, Eric P. Zorrilla

Neuropsychopharmacology. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: Neuropsychopharmacology. 2009 May; 34(6): 1482–1493. Published online 2008 Oct 22. doi: 10.1038/npp.2008.192

PMCID:: PMC2669694

Abstract Article PDF–1.2M

Select item 52200214.

Sigma-1 receptors at galactosylceramide-enriched lipid microdomains regulate oligodendrocyte differentiation

Teruo Hayashi, Tsung-Ping Su

Proc Natl Acad Sci U S A. 2004 Oct 12; 101(41): 14949–14954. Published online 2004 Oct 4. doi: 10.1073/pnas.0402890101

PMCID:: PMC522002

Abstract Article PDF–749K

Select item 1110761215.

CREB decreases astrocytic excitability by modifying subcellular calcium fluxes via the sigma-1 receptor

A. Eraso-Pichot, R. Larramona-Arcas, E. Vicario-Orri, R. Villalonga, L. Pardo, E. Galea, R. Masgrau

Cell Mol Life Sci. 2017 Mar; 74(5): 937–950. Published online 2016 Oct 19. doi: 10.1007/s00018-016-2397-5

PMCID:: PMC11107612

Abstract Article PDF–2.3M

Select item 555083416.

Crystal structure of the human s₁ receptor

Hayden R. Schmidt, Sanduo Zheng, Esin Gurpinar, Antoine Koehl, Aashish Manglik, Andrew C. Kruse

Nature. Author manuscript; available in PMC 2017 Aug 10.

Published in final edited form as: Nature. 2016 Apr 28; 532(7600): 527–530. Published online 2016 Apr 4. doi: 10.1038/nature17391

PMCID:: PMC5550834

Abstract Article PDF–3.3M

Select item 551854217.

Sigmar1 regulates endoplasmic reticulum stress-induced C/EBP-homologous protein expression in cardiomyocytes

Shafiul Alam, Chowdhury S. Abdullah, Richa Aishwarya, A. Wayne Orr, James Traylor, Sumitra Miriyala, Manikandan Panchatcharam, Christopher B. Pattillo, Md. Shenuarin Bhuiyan

Biosci Rep. 2017 Aug 31; 37(4): BSR20170898. Prepublished online 2017 Jun 30. Published online 2017 Jul 17. doi: 10.1042/BSR20170898