PMC Links for Gene (Select 306009) - PMC

Select item 54819391.

Metal Transporter Zip14 (Slc39a14) Deletion in Mice Increases Manganese Deposition and Produces Neurotoxic Signatures and Diminished Motor Activity

Tolunay Beker Aydemir, Min-Hyun Kim, Jinhee Kim, Luis M. Colon-Perez, Guita Banan, Thomas H. Mareci, Marcelo Febo, Robert J. Cousins

J Neurosci. 2017 Jun 21; 37(25): 5996–6006. doi: 10.1523/JNEUROSCI.0285-17.2017

PMCID:: PMC5481939

Abstract Article PDF–2.4M

Select item 31915632.

Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron

Jorge J. Pinilla-Tenas, Brian K. Sparkman, Ali Shawki, Anthony C. Illing, Colin J. Mitchell, Ningning Zhao, Juan P. Liuzzi, Robert J. Cousins, Mitchell D. Knutson, Bryan Mackenzie

Am J Physiol Cell Physiol. 2011 Oct; 301(4): C862–C871. Published online 2011 Jun 8. doi: 10.1152/ajpcell.00479.2010

PMCID:: PMC3191563

Abstract Article

Select item 15642353.

Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells

Juan P. Liuzzi, Fikret Aydemir, Hyeyoung Nam, Mitchell D. Knutson, Robert J. Cousins

Proc Natl Acad Sci U S A. 2006 Sep 12; 103(37): 13612–13617. Published online 2006 Sep 1. doi: 10.1073/pnas.0606424103

PMCID:: PMC1564235

Abstract Article PDF–1.1M

Select item 65565834.

The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis

Ivo Florin Scheiber, Yuze Wu, Shannon Elizabeth Morgan, Ningning Zhao

J Biol Chem. 2019 Jun 7; 294(23): 9147–9160. Published online 2019 Apr 26. doi: 10.1074/jbc.RA119.008762

PMCID:: PMC6556583

Abstract Article PDF–2.7M

Select item 29522155.

ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin

Ningning Zhao, Junwei Gao, Caroline A. Enns, Mitchell D. Knutson

J Biol Chem. 2010 Oct 15; 285(42): 32141–32150. Published online 2010 Aug 3. doi: 10.1074/jbc.M110.143248

PMCID:: PMC2952215

Abstract Article PDF–2.4M

Select item 69165086.

The solute carriers ZIP8 and ZIP14 regulate manganese accumulation in brain microvascular endothelial cells and control brain manganese levels

Brittany L. Steimle, Frances M. Smith, Daniel J. Kosman

J Biol Chem. 2019 Dec 13; 294(50): 19197–19208. Published online 2019 Nov 7. doi: 10.1074/jbc.RA119.009371

PMCID:: PMC6916508

Abstract Article PDF–1.2M

Select item 59036757.

Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis

Gretl Hendrickx, Vere M. Borra, Ellen Steenackers, Timur A. Yorgan, Christophe Hermans, Eveline Boudin, Jérôme J. Waterval, Ineke D. C. Jansen, Tolunay Beker Aydemir, Niels Kamerling, Geert J. Behets, Christine Plumeyer, Patrick C. D’Haese, Björn Busse, Vincent Everts, Martin Lammens, Geert Mortier, Robert J. Cousins, Thorsten Schinke, Robert J. Stokroos, Johannes J. Manni, Wim Van Hul

PLoS Genet. 2018 Apr; 14(4): e1007321. Published online 2018 Apr 5. doi: 10.1371/journal.pgen.1007321

PMCID:: PMC5903675

Abstract Article PDF–19M

Select item 32205518.

Biochemical Characterization of Human ZIP13 Protein: A HOMO-DIMERIZED ZINC TRANSPORTER INVOLVED IN THE SPONDYLOCHEIRO DYSPLASTIC EHLERS-DANLOS SYNDROME

Bum-Ho Bin, Toshiyuki Fukada, Toshiaki Hosaka, Satoru Yamasaki, Wakana Ohashi, Shintaro Hojyo, Tomohiro Miyai, Keigo Nishida, Shigeyuki Yokoyama, Toshio Hirano

J Biol Chem. 2011 Nov 18; 286(46): 40255–40265. Published online 2011 Sep 14. doi: 10.1074/jbc.M111.256784

PMCID:: PMC3220551

Abstract Article PDF–2.7M

Select item 27532109.

Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter

Kuppuswami Girijashanker, Lei He, Manoocher Soleimani, Jodie M. Reed, Hong Li, Zhiwei Liu, Bin Wang, Timothy P. Dalton, Daniel W. Nebert

Mol Pharmacol. Author manuscript; available in PMC 2009 Sep 28.

Published in final edited form as: Mol Pharmacol. 2008 May; 73(5): 1413–1423. Published online 2008 Feb 12. doi: 10.1124/mol.107.043588

Correction in:: Mol Pharmacol, volume 74 on page 924

PMCID:: PMC2753210

Abstract Article PDF–1.4M

Select item 510492010.

Hepatic ZIP14-mediated Zinc Transport Contributes to Endosomal Insulin Receptor Trafficking and Glucose Metabolism

Tolunay Beker Aydemir, Catalina Troche, Min-Hyun Kim, Robert J. Cousins

J Biol Chem. 2016 Nov 11; 291(46): 23939–23951. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748632

PMCID:: PMC5104920

Abstract Article PDF–2.9M

Select item 489498011.

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism–dystonia

Karin Tuschl, Esther Meyer, Leonardo E. Valdivia, Ningning Zhao, Chris Dadswell, Alaa Abdul-Sada, Christina Y. Hung, Michael A. Simpson, W. K. Chong, Thomas S. Jacques, Randy L. Woltjer, Simon Eaton, Allison Gregory, Lynn Sanford, Eleanna Kara, Henry Houlden, Stephan M. Cuno, Holger Prokisch, Lorella Valletta, Valeria Tiranti, Rasha Younis, Eamonn R. Maher, John Spencer, Ania Straatman-Iwanowska, Paul Gissen, Laila A. M. Selim, Guillem Pintos-Morell, Wifredo Coroleu-Lletget, Shekeeb S. Mohammad, Sangeetha Yoganathan, Russell C. Dale, Maya Thomas, Jason Rihel, Olaf A. Bodamer, Caroline A. Enns, Susan J. Hayflick, Peter T. Clayton, Philippa B. Mills, Manju A. Kurian, Stephen W. Wilson

Nat Commun. 2016; 7: 11601. Published online 2016 May 27. doi: 10.1038/ncomms11601

PMCID:: PMC4894980

Abstract Article PDF–3.7M

Select item 306256712.

The Zinc Transporter SLC39A14/ZIP14 Controls G-Protein Coupled Receptor-Mediated Signaling Required for Systemic Growth

Shintaro Hojyo, Toshiyuki Fukada, Shinji Shimoda, Wakana Ohashi, Bum-Ho Bin, Haruhiko Koseki, Toshio Hirano

PLoS One. 2011; 6(3): e18059. Published online 2011 Mar 22. doi: 10.1371/journal.pone.0018059

PMCID:: PMC3062567

Abstract Article PDF–1.4M

Select item 478325413.

Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease

Alexander R. Bogdan, Masaki Miyazawa, Kazunori Hashimoto, Yoshiaki Tsuji

Trends Biochem Sci. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Trends Biochem Sci. 2016 Mar; 41(3): 274–286. Published online 2015 Dec 23. doi: 10.1016/j.tibs.2015.11.012

PMCID:: PMC4783254

Abstract Article PDF–1.6M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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