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Select item 92510521.

High abundance of CDC45 inhibits cell proliferation through elevation of HSPA6

Yuanyuan Fu, Zhiyi Lv, Deqing Kong, Yuping Fan, Bo Dong

Cell Prolif. 2022 Jul; 55(7): e13257. Published online 2022 Jun 1. doi: 10.1111/cpr.13257

PMCID:: PMC9251052

Abstract Article PDF–2.6M

Select item 43666482.

DNA Copy Number Control Through Inhibition of Replication Fork Progression

Jared T. Nordman, Elena N. Kozhevnikova, C. Peter Verrijzer, Alexey V. Pindyurin, Evgeniya N. Andreyeva, Victor V. Shloma, Igor F. Zhimulev, Terry L. Orr-Weaver

Cell Rep. Author manuscript; available in PMC 2015 Nov 6.

Published in final edited form as: Cell Rep. 2014 Nov 6; 9(3): 841–849. Published online 2014 Oct 30. doi: 10.1016/j.celrep.2014.10.005

PMCID:: PMC4366648

Abstract Article PDF–1.0M

Select item 3653833.

Molecular cloning and genetic analysis of the suppressor-of-white-apricot locus from Drosophila melanogaster.

Z Zachar, D Garza, T B Chou, J Goland, P M Bingham

Mol Cell Biol. 1987 Jul; 7(7): 2498–2505. doi: 10.1128/mcb.7.7.2498

PMCID:: PMC365383

Summary Page Browse PDF–1.8M

Select item 1107854.

Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification

David Loebel, Hella Huikeshoven, Sue Cotterill

Nucleic Acids Res. 2000 Oct 15; 28(20): 3897–3903. doi: 10.1093/nar/28.20.3897

PMCID:: PMC110785

Abstract Article PDF–784K

Select item 38169675.

Functional analysis of Drosophila DNA polymerase ε p58 subunit

Ritsuko Sahashi, Risa Matsuda, Osamu Suyari, Mieko Kawai, Hideki Yoshida, Sue Cotterill, Masamitsu Yamaguchi

Am J Cancer Res. 2013; 3(5): 478–489. Published online 2013 Nov 1.

PMCID:: PMC3816967

Abstract Article PDF–2.5M

Select item 19506846.

Differential Requirements for MCM Proteins in DNA Replication in Drosophila S2 Cells

Gilles Crevel, Reina Hashimoto, Sharron Vass, Jake Sherkow, Masamitsu Yamaguchi, Margarete M.S. Heck, Sue Cotterill

PLoS One. 2007; 2(9): e833. Published online 2007 Sep 5. doi: 10.1371/journal.pone.0000833

PMCID:: PMC1950684

Abstract Article PDF–387K

Select item 65174137.

The mechanism of DNA unwinding by the eukaryotic replicative helicase

Daniel R. Burnham, Hazal B. Kose, Rebecca B. Hoyle, Hasan Yardimci

Nat Commun. 2019; 10: 2159. Published online 2019 May 14. doi: 10.1038/s41467-019-09896-2

PMCID:: PMC6517413

Abstract Article PDF–1.2M

Select item 73824678.

Duplex DNA engagement and RPA oppositely regulate the DNA-unwinding rate of CMG helicase

Hazal B. Kose, Sherry Xie, George Cameron, Melania S. Strycharska, Hasan Yardimci

Nat Commun. 2020; 11: 3713. Published online 2020 Jul 24. doi: 10.1038/s41467-020-17443-7

PMCID:: PMC7382467

Abstract Article PDF–2.6M

Select item 63962939.

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS proteins

Ivar Ilves, Tatjana Petojevic, James J. Pesavento, Michael R. Botchan

Mol Cell. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Mol Cell. 2010 Jan 29; 37(2): 247–258. doi: 10.1016/j.molcel.2009.12.030

PMCID:: PMC6396293

Abstract Article PDF–1007K

Select item 435936710.

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome

Alessandro Costa, Ludovic Renault, Paolo Swuec, Tatjana Petojevic, James J Pesavento, Ivar Ilves, Kirsty MacLellan-Gibson, Roland A Fleck, Michael R Botchan, James M Berger

eLife. 2014; 3: e03273. Published online 2014 Aug 12. doi: 10.7554/eLife.03273

PMCID:: PMC4359367

Abstract Article PDF–3.2M

Select item 418403311.

The structural basis for MCM2–7 helicase activation by GINS and Cdc45

Alessandro Costa, Ivar Ilves, Nele Tamberg, Tatjana Petojevic, Eva Nogales, Michael R Botchan, James M Berger

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Oct 3.

Published in final edited form as: Nat Struct Mol Biol. 2011 Apr; 18(4): 471–477. Published online 2011 Mar 6. doi: 10.1038/nsmb.2004

PMCID:: PMC4184033

Abstract Article PDF–1.2M

Select item 148246712.

Isolation of the Cdc45/Mcm2–7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

Stephen E. Moyer, Peter W. Lewis, Michael R. Botchan

Proc Natl Acad Sci U S A. 2006 Jul 5; 103(27): 10236–10241. Published online 2006 Jun 23. doi: 10.1073/pnas.0602400103

PMCID:: PMC1482467

Abstract Article PDF–1.4M

Select item 342122413.

Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex

Ivar Ilves, Nele Tamberg, Michael R. Botchan

Proc Natl Acad Sci U S A. 2012 Aug 14; 109(33): 13163–13170. Published online 2012 Aug 1. doi: 10.1073/pnas.1211525109

PMCID:: PMC3421224

Abstract Article PDF–1.4M

Select item 19487114.

Drosophila Mcm10 Interacts with Members of the Prereplication Complex and Is Required for Proper Chromosome Condensation

Tim W. Christensen, Bik K. Tye

Mol Biol Cell. 2003 Jun; 14(6): 2206–2215. doi: 10.1091/mbc.E02-11-0706

PMCID:: PMC194871

Abstract Article PDF–409K

Select item 367549515.

Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome

Nadezhda E. Vorobyeva, Marina U. Mazina, Anton K. Golovnin, Daria V. Kopytova, Dmitriy Y. Gurskiy, Elena N. Nabirochkina, Sofia G. Georgieva, Pavel G. Georgiev, Aleksey N. Krasnov

Nucleic Acids Res. 2013 Jun; 41(11): 5717–5730. Published online 2013 Apr 22. doi: 10.1093/nar/gkt297