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Select item 69433681.

Increased HLA-DR expression and cortical demyelination in MS links with HLA-DR15

Lukas Simon Enz, Thomas Zeis, Daniela Schmid, Florian Geier, Franziska van der Meer, Guido Steiner, Ulrich Certa, Thomas Martin Christian Binder, Christine Stadelmann, Roland Martin, Nicole Schaeren-Wiemers

Neurol Neuroimmunol Neuroinflamm. 2020 Mar; 7(2): e656. Published online 2019 Dec 27. doi: 10.1212/NXI.0000000000000656

PMCID:: PMC6943368

Abstract Article PDF–1.2M

Select item 49057832.

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

Jennifer S. Yokoyama, Yunpeng Wang, Andrew J. Schork, Wesley K. Thompson, Celeste M. Karch, Carlos Cruchaga, Linda K. McEvoy, Aree Witoelar, Chi-Hua Chen, Dominic Holland, James B. Brewer, Andre Franke, William P. Dillon, David M. Wilson, Pratik Mukherjee, Christopher P. Hess, Zachary Miller, Luke W. Bonham, Jeffrey Shen, Gil D. Rabinovici, Howard J. Rosen, Bruce L. Miller, Bradley T. Hyman, Gerard D. Schellenberg, Tom H. Karlsen, Ole A. Andreassen, Anders M. Dale, Rahul S. Desikan

JAMA Neurol. Author manuscript; available in PMC 2016 Jun 13.

Published in final edited form as: JAMA Neurol. 2016 Jun 1; 73(6): 691–697. doi: 10.1001/jamaneurol.2016.0150

PMCID:: PMC4905783

Abstract Article PDF–357K

Select item 43463273.

Uncoupling the Roles of HLA-DRB1 and HLA-DRB5 Genes in Multiple Sclerosis

Stacy J. Caillier, Farren Briggs, Bruce A. C. Cree, Sergio E. Baranzini, Marcelo Fernandez-Viña, Patricia P. Ramsay, Omar Khan, Walter Royal, III, Stephen L. Hauser, Lisa F. Barcellos, Jorge R. Oksenberg

J Immunol. Author manuscript; available in PMC 2015 Mar 2.

Published in final edited form as: J Immunol. 2008 Oct 15; 181(8): 5473–5480. doi: 10.4049/jimmunol.181.8.5473

Correction in:: volume 182 on page 2551

PMCID:: PMC4346327

Abstract Article PDF–770K

Select item 11995394.

Ancient haplotypes of the HLA Class II region

Christopher K. Raymond, Arnold Kas, Marcia Paddock, Ruolan Qiu, Yang Zhou, Sandhya Subramanian, Jean Chang, Anthony Palmieri, Eric Haugen, Rajinder Kaul, Maynard V. Olson

Genome Res. 2005 Sep; 15(9): 1250–1257. doi: 10.1101/gr.3554305

PMCID:: PMC1199539

Abstract Article PDF–507K

Select item 3051365.

HLA-DR2 subtypes form an additional supertypic family of DR beta alleles.

B S Lee, N A Rust, A J McMichael, H O McDevitt

Proc Natl Acad Sci U S A. 1987 Jul; 84(13): 4591–4595. doi: 10.1073/pnas.84.13.4591

PMCID:: PMC305136

Summary Page Browse PDF–1.2M

Select item 67977756.

Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia

Fedor E. Gusev, Denis A. Reshetov, Amanda C. Mitchell, Tatiana V. Andreeva, Aslihan Dincer, Anastasia P. Grigorenko, Gennady Fedonin, Tobias Halene, Maria Aliseychik, Elena Filippova, Zhiping Weng, Schahram Akbarian, Evgeny I. Rogaev

Transl Psychiatry. 2019; 9: 256. Published online 2019 Oct 17. doi: 10.1038/s41398-019-0596-1

PMCID:: PMC6797775

Abstract Article PDF–1.2M

Select item 63457917.

Interactions of HLA-DR and Topoisomerase I Epitope Modulated Genetic Risk for Systemic Sclerosis

Sirilak Kongkaew, Thanyada Rungrotmongkol, Chutintorn Punwong, Hiroshi Noguchi, Fujio Takeuchi, Nawee Kungwan, Peter Wolschann, Supot Hannongbua

Sci Rep. 2019; 9: 745. Published online 2019 Jan 24. doi: 10.1038/s41598-018-37038-z

PMCID:: PMC6345791

Abstract Article PDF–7.4M

Select item 30566398.

Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL

Susan L. Slager, Kari G. Rabe, Sara J. Achenbach, Celine M. Vachon, Lynn R. Goldin, Sara S. Strom, Mark C. Lanasa, Logan G. Spector, Laura Z. Rassenti, Jose F. Leis, Nicola J. Camp, Martha Glenn, Neil E. Kay, Julie M. Cunningham, Curtis A. Hanson, Gerald E. Marti, J. Brice Weinberg, Vicki A. Morrison, Brian K. Link, Timothy G. Call, Neil E. Caporaso, James R. Cerhan

Blood. 2011 Feb 10; 117(6): 1911–1916. Prepublished online 2010 Dec 3. doi: 10.1182/blood-2010-09-308205

PMCID:: PMC3056639

Abstract Article

Select item 27240679.

Myelin-reactive “type B” T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice

Kazuyuki Kawamura, Katherine A. McLaughlin, Robert Weissert, Thomas G. Forsthuber

J Immunol. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: J Immunol. 2008 Sep 1; 181(5): 3202–3211. doi: 10.4049/jimmunol.181.5.3202

PMCID:: PMC2724067

Abstract Article PDF–1.0M

Select item 38709210.

Polymorphism of HLA-DR beta chains in DR4, -7, and -9 haplotypes: implications for the mechanisms of allelic variation.

P K Gregersen, T Moriuchi, R W Karr, F Obata, J Moriuchi, J Maccari, D Goldberg, R J Winchester, J Silver

Proc Natl Acad Sci U S A. 1986 Dec; 83(23): 9149–9153. doi: 10.1073/pnas.83.23.9149

PMCID:: PMC387092

Summary Page Browse PDF–828K

Select item 5151711.

Allelic diversity is generated by intraexon sequence exchange at the DRB1 locus of primates.

U B Gyllensten, M Sundvall, H A Erlich

Proc Natl Acad Sci U S A. 1991 May 1; 88(9): 3686–3690. doi: 10.1073/pnas.88.9.3686

PMCID:: PMC51517

Summary Page Browse PDF–832K

Select item 476414712.

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes

Lue Ping Zhao, Shehab Alshiekh, Michael Zhao, Annelie Carlsson, Helena Elding Larsson, Gun Forsander, Sten A. Ivarsson, Johnny Ludvigsson, Ingrid Kockum, Claude Marcus, Martina Persson, Ulf Samuelsson, Eva Örtqvist, Chul-Woo Pyo, Wyatt C. Nelson, Daniel E. Geraghty, Åke Lernmark

Diabetes. 2016 Mar; 65(3): 710–718. Published online 2016 Jan 6. doi: 10.2337/db15-1115

PMCID:: PMC4764147

Abstract Article PDF–2.0M

Select item 411212613.

Frontotemporal dementia and its subtypes: a genome-wide association study

Raffaele Ferrari, Dena G Hernandez, Michael A Nalls, Jonathan D Rohrer, Adaikalavan Ramasamy, John B J Kwok, Carol Dobson-Stone, William S Brooks, Peter R Schofield, Glenda M Halliday, John R Hodges, Olivier Piguet, Lauren Bartley, Elizabeth Thompson, Eric Haan, Isabel Hernández, Agustín Ruiz, Mercè Boada, Barbara Borroni, Alessandro Padovani, Carlos Cruchaga, Nigel J Cairns, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Gianluigi Forloni, Daniela Galimberti, Chiara Fenoglio, Maria Serpente, Elio Scarpini, Jordi Clarimón, Alberto Lleó, Rafael Blesa, Maria Landqvist Waldö, Karin Nilsson, Christer Nilsson, Ian R A Mackenzie, Ging-Yuek R Hsiung, David M A Mann, Jordan Grafman, Christopher M Morris, Johannes Attems, Timothy D Griffiths, Ian G McKeith, Alan J Thomas, P Pietrini, Edward D Huey, Eric M Wassermann, Atik Baborie, Evelyn Jaros, Michael C Tierney, Pau Pastor, Cristina Razquin, Sara Ortega-Cubero, Elena Alonso, Robert Perneczky, Janine Diehl-Schmid, Panagiotis Alexopoulos, Alexander Kurz, Innocenzo Rainero, Elisa Rubino, Lorenzo Pinessi, Ekaterina Rogaeva, Peter St George-Hyslop, Giacomina Rossi, Fabrizio Tagliavini, Giorgio Giaccone, James B Rowe, J C M Schlachetzki, James Uphill, John Collinge, S Mead, Adrian Danek, Vivianna M Van Deerlin, Murray Grossman, John Q Trojanowsk, Julie van der Zee, William Deschamps, Tim Van Langenhove, Marc Cruts, Christine Van Broeckhoven, Stefano F Cappa, Isabelle Le Ber, Didier Hannequin, Véronique Golfier, Martine Vercelletto, Alexis Brice, Benedetta Nacmias, Sandro Sorbi, Silvia Bagnoli, Irene Piaceri, Jørgen E Nielsen, Lena E Hjermind, Matthias Riemenschneider, Manuel Mayhaus, Bernd Ibach, Gilles Gasparoni, Sabrina Pichler, Wei Gu, Martin N Rossor, Nick C Fox, Jason D Warren, Maria Grazia Spillantini, Huw R Morris, Patrizia Rizzu, Peter Heutink, Julie S Snowden, Sara Rollinson, Anna Richardson, Alexander Gerhard, Amalia C Bruni, Raffaele Maletta, Francesca Frangipane, Chiara Cupidi, Livia Bernardi, Maria Anfossi, Maura Gallo, Maria Elena Conidi, Nicoletta Smirne, Rosa Rademakers, Matt Baker, Dennis W Dickson, Neill R Graff-Radford, Ronald C Petersen, David Knopman, Keith A Josephs, Bradley F Boeve, Joseph E Parisi, William W Seeley, Bruce L Miller, Anna M Karydas, Howard Rosen, John C van Swieten, Elise G P Dopper, Harro Seelaar, Yolande AL Pijnenburg, Philip Scheltens, Giancarlo Logroscino, Rosa Capozzo, Valeria Novelli, Annibale A Puca, M Franceschi, Alfredo Postiglione, Graziella Milan, Paolo Sorrentino, Mark Kristiansen, Huei-Hsin Chiang, Caroline Graff, Florence Pasquier, Adeline Rollin, Vincent Deramecourt, Florence Lebert, Dimitrios Kapogiannis, Luigi Ferrucci, Stuart Pickering-Brown, Andrew B Singleton, John Hardy, Parastoo Momeni

Lancet Neurol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Lancet Neurol. 2014 Jul; 13(7): 686–699. doi: 10.1016/S1474-4422(14)70065-1

PMCID:: PMC4112126

Abstract Article PDF–829K

Select item 343697014.

Myelin Basic Protein-Specific TCR/HLA-DRB5*01:01Transgenic Mice Support the Etiologic Role of DRB5*01:01 in Multiple Sclerosis

Jacqueline A. Quandt, Jaebong Huh, Mirza Baig, Karen Yao, Naoko Ito, Mark Bryant, Kazuyuki Kawamura, Clemencia Pinilla, Henry F. McFarland, Roland Martin, Kouichi Ito

J Immunol. Author manuscript; available in PMC 2013 Sep 15.

Published in final edited form as: J Immunol. 2012 Sep 15; 189(6): 2897–2908. Published online 2012 Aug 10. doi: 10.4049/jimmunol.1103087

PMCID:: PMC3436970

Abstract Article PDF–2.1M

Select item 267860915.

Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility

Matthew R. Lincoln, Sreeram V. Ramagopalan, Michael J. Chao, Blanca M. Herrera, Gabriele C. DeLuca, Sarah-Michelle Orton, David A. Dyment, A Dessa Sadovnick, George C. Ebers

Proc Natl Acad Sci U S A. 2009 May 5; 106(18): 7542–7547. Published online 2009 Apr 20. doi: 10.1073/pnas.0812664106

PMCID:: PMC2678609

Abstract Article PDF–335K

Select item 172809516.

Co-amoxiclav jaundice: clinical and histological features and HLA class II association

J O'Donohue, K Oien, P Donaldson, J Underhill, M Clare, R MacSween, P Mills

Gut. 2000 Nov; 47(5): 717–720. doi: 10.1136/gut.47.5.717

PMCID:: PMC1728095

Summary PDF–143K

Select item 29904517.

Allelic variation in the DR subregion of the human major histocompatibility complex.

J I Bell, D Denney, Jr, L Foster, T Belt, J A Todd, H O McDevitt

Proc Natl Acad Sci U S A. 1987 Sep; 84(17): 6234–6238. doi: 10.1073/pnas.84.17.6234

PMCID:: PMC299045

Summary Page Browse PDF–1.1M

Select item 434436718.

Association of Brain DNA Methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 With Pathological Diagnosis of Alzheimer Disease

Lei Yu, Lori B. Chibnik, Gyan P. Srivastava, Nathalie Pochet, Jingyun Yang, Jishu Xu, James Kozubek, Nikolaus Obholzer, Sue E. Leurgans, Julie A. Schneider, Alexander Meissner, Philip L. De Jager, David A. Bennett

JAMA Neurol. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: JAMA Neurol. 2015 Jan 1; 72(1): 15–24. doi: 10.1001/jamaneurol.2014.3049

PMCID:: PMC4344367

Abstract Article PDF–1.3M

Select item 355413819.

Expansion of Monocytic Myeloid-Derived Suppressor Cells Dampens T Cell Function in HIV-1-Seropositive Individuals

Aiping Qin, Weiping Cai, Ting Pan, Kang Wu, Qiong Yang, Nina Wang, Yufeng Liu, Dehong Yan, Fengyu Hu, Pengle Guo, Xiaoping Chen, Ling Chen, Hui Zhang, Xiaoping Tang, Jie Zhou

J Virol. 2013 Feb; 87(3): 1477–1490. doi: 10.1128/JVI.01759-12

PMCID:: PMC3554138

Abstract Article PDF–2.4M

Select item 193334420.

Productive Human Immunodeficiency Virus Type 1 Assembly Takes Place at the Plasma Membrane

Andrés Finzi, Alexandre Orthwein, Johanne Mercier, Éric A. Cohen

J Virol. 2007 Jul; 81(14): 7476–7490. Published online 2007 May 16. doi: 10.1128/JVI.00308-07

PMCID:: PMC1933344

Abstract Article PDF–890K

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