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Items: 1 to 20 of 25

1.
Age-related Changes in p56lck Protein Levels and Phenotypic Distribution of T Lymphocytes in Young Rats
Heather J. Hosea, Edward S. Rector, Carla G. Taylor
Clin Dev Immunol. 2005 Mar; 12(1): 75–84. doi: 10.1080/17402520400017393
PMCID:
PMC2270719
SummaryPDF–557K
2.
In vitro membrane reconstitution of the T cell receptor proximal signaling network
Enfu Hui, Ronald D. Vale
Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Nat Struct Mol Biol. 2014 Feb; 21(2): 133–142. Published online 2014 Jan 26. doi: 10.1038/nsmb.2762
PMCID:
PMC4062301
AbstractArticlePDF–1.7M
3.
Identification of the dichotomous role of age-related LCK in calorie restriction revealed by integrative analysis of cDNA microarray and interactome
Daeui Park, Eun Kyeong Lee, Eun Jee Jang, Hyoung Oh Jeong, Byoung-Chul Kim, Young Mi Ha, Seong Eui Hong, Byung Pal Yu, Hae Young Chung
Age (Dordr) 2013 Aug; 35(4): 1045–1060. Published online 2012 Jul 25. doi: 10.1007/s11357-012-9426-6
PMCID:
PMC3705109
AbstractArticlePDF–743K
4.
Role of Non-receptor Protein Tyrosine Kinases During Phospholipase C-γ1 Related Uterine Contractions in the Rat
Mark Phillippe, Leigh M. Sweet, Diana F. Bradley, Daniel Engle
Reprod Sci. Author manuscript; available in PMC 2011 May 7.
Published in final edited form as: Reprod Sci. 2009 Mar; 16(3): 265–273. doi: 10.1177/1933719108327598
PMCID:
PMC3089769
AbstractArticlePDF–2.0M
5.
Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes
J Cell Biol. 1994 May 1; 125(3): 639–649. doi: 10.1083/jcb.125.3.639
PMCID:
PMC2119993
SummaryPDF–2.2M
6.
The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization.
S Yamasaki, M Takamatsu, M Iwashima
Mol Cell Biol. 1996 Dec; 16(12): 7151–7160. doi: 10.1128/mcb.16.12.7151
PMCID:
PMC231719
SummaryPDF–422K
7.
Lck tyrosine kinase mediates β1-integrin signalling to regulate Schwann cell migration and myelination
Jennifer K. Ness, Kristin M. Snyder, Nikos Tapinos
Nat Commun. 2013 May 28; 4: 1912. Published online 2013 May 28. doi: 10.1038/ncomms2928
PMCID:
PMC3674276
AbstractArticlePDF–5.7M
8.
Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts
Dominik Filipp, Jenny Zhang, Bernadine L. Leung, Andrey Shaw, Steven D. Levin, André Veillette, Michael Julius
J Exp Med. 2003 May 5; 197(9): 1221–1227. doi: 10.1084/jem.20022112
PMCID:
PMC2193969
AbstractArticlePDF–240K
9.
The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes.
L B Vogel, D J Fujita
Mol Cell Biol. 1993 Dec; 13(12): 7408–7417. doi: 10.1128/mcb.13.12.7408
PMCID:
PMC364812
SummaryPage BrowsePDF–2.7M
10.
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.
E K Barber, J D Dasgupta, S F Schlossman, J M Trevillyan, C E Rudd
Proc Natl Acad Sci U S A. 1989 May; 86(9): 3277–3281. doi: 10.1073/pnas.86.9.3277
PMCID:
PMC287114
SummaryPage BrowsePDF–1.4M
11.
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice
Florian Wiede, Benjamin J. Shields, Sock Hui Chew, Konstantinos Kyparissoudis, Catherine van Vliet, Sandra Galic, Michel L. Tremblay, Sarah M. Russell, Dale I. Godfrey, Tony Tiganis
J Clin Invest. 2011 Dec 1; 121(12): 4758–4774. Published online 2011 Nov 14. doi: 10.1172/JCI59492
Correction in:
J Clin Invest. 2023 Oct 16; 133(20): e175163.
PMCID:
PMC3226006
AbstractArticlePDF–4.7M
12.
The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5).
J C O'Connell, J F McCallum, I McPhee, J Wakefield, E S Houslay, W Wishart, G Bolger, M Frame, M D Houslay
Biochem J. 1996 Aug 15; 318(Pt 1): 255–261. doi: 10.1042/bj3180255
PMCID:
PMC1217616
SummaryPDF–419K
13.
Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity.
A Greenway, A Azad, J Mills, D McPhee
J Virol. 1996 Oct; 70(10): 6701–6708. doi: 10.1128/jvi.70.10.6701-6708.1996
PMCID:
PMC190712
SummaryPDF–281K
14.
SOCS-6 Negatively Regulates T Cell Activation through Targeting p56lck to Proteasomal Degradation
Young Bong Choi, Myoungsun Son, Mijin Park, Jaekyoon Shin, Yungdae Yun
J Biol Chem. 2010 Mar 5; 285(10): 7271–7280. Published online 2009 Dec 10. doi: 10.1074/jbc.M109.073726
PMCID:
PMC2844175
AbstractArticlePDF–1.4M
15.
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck.
D G Winkler, I Park, T Kim, N S Payne, C T Walsh, J L Strominger, J Shin
Proc Natl Acad Sci U S A. 1993 Jun 1; 90(11): 5176–5180. doi: 10.1073/pnas.90.11.5176
PMCID:
PMC46678
SummaryPage BrowsePDF–1.7M
16.
Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.
I Park, J Chung, C T Walsh, Y Yun, J L Strominger, J Shin
Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26): 12338–12342. doi: 10.1073/pnas.92.26.12338
PMCID:
PMC40352
SummaryPage BrowsePDF–1.7M
17.
Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling
Kenrick Semple, Antony Nguyen, Yu Yu, Honglin Wang, Claudio Anasetti, Xue-Zhong Yu
Blood. 2011 Mar 17; 117(11): 3096–3103. Prepublished online 2011 Jan 18. doi: 10.1182/blood-2010-08-301275
PMCID:
PMC3062312
AbstractArticle
18.
Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase- deficient mice
J Exp Med. 1995 Jan 1; 181(1): 345–349. doi: 10.1084/jem.181.1.345
PMCID:
PMC2191823
SummaryPDF–619K
19.
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
Yonghao Cao, Hai Li, Haifeng Liu, Min Zhang, Zichun Hua, Hongbin Ji, Xiaolong Liu
EMBO J. 2011 May 18; 30(10): 2083–2093. Published online 2011 Apr 12. doi: 10.1038/emboj.2011.116
PMCID:
PMC3098487
AbstractArticlePDF–1.8M
20.
Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation.
I Timokhina, H Kissel, G Stella, P Besmer
EMBO J. 1998 Nov 2; 17(21): 6250–6262. doi: 10.1093/emboj/17.21.6250
PMCID:
PMC1170951
SummaryPDF–518K

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