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Select item 95651571.

CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model

Jiaxi Yu, Tongling Liufu, Yilei Zheng, Jin Xu, Lingchao Meng, Wei Zhang, Yun Yuan, Daojun Hong, Nicolas Charlet-Berguerand, Zhaoxia Wang, Jianwen Deng

Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2208649119. Published online 2022 Oct 3. doi: 10.1073/pnas.2208649119

PMCID:: PMC9565157

Abstract Article PDF–3.1M

Select item 36909682.

TRAP1 rescues PINK1 loss-of-function phenotypes

Li Zhang, Peter Karsten, Sabine Hamm, Joe H. Pogson, A. Kathrin Müller-Rischart, Nicole Exner, Christian Haass, Alexander J. Whitworth, Konstanze F. Winklhofer, Jörg B. Schulz, Aaron Voigt

Hum Mol Genet. 2013 Jul 15; 22(14): 2829–2841. Published online 2013 Mar 21. doi: 10.1093/hmg/ddt132

PMCID:: PMC3690968

Abstract Article PDF–890K

Select item 32523003.

The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

Sven Vilain, Giovanni Esposito, Dominik Haddad, Onno Schaap, Mariya P. Dobreva, Melissa Vos, Stefanie Van Meensel, Vanessa A. Morais, Bart De Strooper, Patrik Verstreken

PLoS Genet. 2012 Jan; 8(1): e1002456. Published online 2012 Jan 5. doi: 10.1371/journal.pgen.1002456

PMCID:: PMC3252300

Abstract Article PDF–1.1M

Select item 97947284.

The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster

Kaniz Fatima Binte Hossain, Anjaneyulu Murari, Bibhuti Mishra, Edward Owusu-Ansah

Sci Rep. 2022; 12: 22433. Published online 2022 Dec 27. doi: 10.1038/s41598-022-26414-5

PMCID:: PMC9794728

Abstract Article PDF–3.7M

Select item 107182855.

Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity

Anjaneyulu Murari, Shauna-Kay Rhooms, Divya Vimal, Kaniz Fatima Binte Hossain, Sanjay Saini, Maximino Villanueva, Michael Schlame, Edward Owusu-Ansah

Cell Rep. Author manuscript; available in PMC 2023 Dec 13.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112846. Published online 2023 Jul 29. doi: 10.1016/j.celrep.2023.112846

PMCID:: PMC10718285

Abstract Article PDF–2.8M

Select item 100361226.

Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state

Abhilash Padavannil, Anjaneyulu Murari, Shauna-Kay Rhooms, Edward Owusu-Ansah, James A Letts

eLife. 2023; 12: e84415. Published online 2023 Mar 23. doi: 10.7554/eLife.84415

PMCID:: PMC10036122

Abstract Article PDF–12M

Select item 99772797.

Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster

Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst

eLife. 2023; 12: e84424. Published online 2023 Jan 9. doi: 10.7554/eLife.84424

PMCID:: PMC9977279

Abstract Article PDF–6.3M

Select item 42389768.

The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

Joe H. Pogson, Rachael M. Ivatt, Alvaro Sanchez-Martinez, Roberta Tufi, Emma Wilson, Heather Mortiboys, Alexander J. Whitworth

PLoS Genet. 2014 Nov; 10(11): e1004815. Published online 2014 Nov 20. doi: 10.1371/journal.pgen.1004815

PMCID:: PMC4238976

Abstract Article PDF–1.8M

Select item 106228409.

Cardiolipin prolongs the lifetimes of respiratory proteins in Drosophila flight muscle

Mindong Ren, Yang Xu, Colin K.L. Phoon, Hediye Erdjument-Bromage, Thomas A. Neubert, Michael Schlame

J Biol Chem. 2023 Oct; 299(10): 105241. Published online 2023 Sep 9. doi: 10.1016/j.jbc.2023.105241

PMCID:: PMC10622840

Abstract Article PDF–1.2M

Select item 728907710.

Insights from Drosophila on mitochondrial complex I

Shauna-Kay Rhooms, Anjaneyulu Murari, Naga Sri Vidya Goparaju, Maximino Vilanueva, Edward Owusu-Ansah

Cell Mol Life Sci. 2020 Feb; 77(4): 607–618. Published online 2019 Sep 4. doi: 10.1007/s00018-019-03293-0

PMCID:: PMC7289077

Abstract Article PDF–881K

Select item 579176211.

Regulation of Mitochondrial Complex I Biogenesis in Drosophila Flight Muscles

Christian Joel Garcia, Jahan Khajeh, Emmanuel Coulanges, Emily I-ju Chen, Edward Owusu-Ansah

Cell Rep. Author manuscript; available in PMC 2018 Jan 31.

Published in final edited form as: Cell Rep. 2017 Jul 5; 20(1): 264–278. doi: 10.1016/j.celrep.2017.06.015

PMCID:: PMC5791762

Abstract Article PDF–2.9M

Select item 753072112.

Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes

Hiro Takahashi, Shido Miyaki, Hitoshi Onouchi, Taichiro Motomura, Nobuo Idesako, Anna Takahashi, Masataka Murase, Shuichi Fukuyoshi, Toshinori Endo, Kenji Satou, Satoshi Naito, Motoyuki Itoh

Sci Rep. 2020; 10: 16289. Published online 2020 Oct 1. doi: 10.1038/s41598-020-73307-6

PMCID:: PMC7530721

Abstract Article PDF–1.1M

Select item 227620913.

Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species

Celine A Hayden, Giovanni Bosco

BMC Genomics. 2008; 9: 61. Published online 2008 Feb 1. doi: 10.1186/1471-2164-9-61

PMCID:: PMC2276209

Abstract Article PDF–323K

Select item 224164114.

The nuclear OXPHOS genes in insecta: a common evolutionary origin, a common cis-regulatory motif, a common destiny for gene duplicates

Damiano Porcelli, Paolo Barsanti, Graziano Pesole, Corrado Caggese

BMC Evol Biol. 2007; 7: 215. Published online 2007 Nov 8. doi: 10.1186/1471-2148-7-215

PMCID:: PMC2241641

Abstract Article PDF–1.5M

Select item 909466715.

IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system

Anjaneyulu Murari, Naga S. V. Goparaju, Shauna-Kay Rhooms, Kaniz F. B. Hossain, Felix G. Liang, Christian J. Garcia, Cindy Osei, Tong Liu, Hong Li, Richard N. Kitsis, Rajesh Patel, Edward Owusu-Ansah

Sci Adv. 2022 May; 8(19): eabl8716. Published online 2022 May 11. doi: 10.1126/sciadv.abl8716

PMCID:: PMC9094667

Abstract Article PDF–21M

Select item 550014016.

Neutral Competition for Drosophila Follicle and Cyst Stem Cell Niches Requires Vesicle Trafficking Genes

Matthew S. Cook, Coralie Cazin, Marc Amoyel, Shinya Yamamoto, Erika Bach, Todd Nystul

Genetics. 2017 Jul; 206(3): 1417–1428. Published online 2017 May 16. doi: 10.1534/genetics.117.201202

PMCID:: PMC5500140

Abstract Article PDF–2.3M

Select item 405386117.

RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins

Zhipeng Lu, Xiaojun Guan, Casey A Schmidt, A Gregory Matera

Genome Biol. 2014; 15(1): R7. Published online 2014 Jan 7. doi: 10.1186/gb-2014-15-1-r7

PMCID:: PMC4053861

Abstract Article PDF–2.0M

Select item 419936318.

Large-scale identification of chemically induced mutations in Drosophila melanogaster

Nele A. Haelterman, Lichun Jiang, Yumei Li, Vafa Bayat, Hector Sandoval, Berrak Ugur, Kai Li Tan, Ke Zhang, Danqing Bei, Bo Xiong, Wu-Lin Charng, Theodore Busby, Adeel Jawaid, Gabriela David, Manish Jaiswal, Koen J.T. Venken, Shinya Yamamoto, Rui Chen, Hugo J. Bellen

Genome Res. 2014 Oct; 24(10): 1707–1718. doi: 10.1101/gr.174615.114