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Select item 95394631.

DDX3X alleviates doxorubicin‐induced cardiotoxicity by regulating Wnt/β‐catenin signaling pathway in an in vitro model

Dandan Feng, Jiang Li, Liang Guo, Jing Liu, Shaochen Wang, Xiuyuan Ma, Yunxuan Song, Ju Liu, Enkui Hao

J Biochem Mol Toxicol. 2022 Aug; 36(8): e23077. Published online 2022 Apr 25. doi: 10.1002/jbt.23077

PMCID:: PMC9539463

Abstract Article PDF–1.7M

Select item 47595882.

DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis

Tsung-Ying He, De-Wei Wu, Po-Lin Lin, Lee Wang, Chi-Chou Huang, Ming-Chih Chou, Huei Lee

Sci Rep. 2016; 6: 21483. Published online 2016 Feb 19. doi: 10.1038/srep21483

PMCID:: PMC4759588

Abstract Article PDF–1.5M

Select item 66859813.

Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3

Rong Fu, Peng Yang, Zongwei Li, Wen Liu, Sajid Amin, Zhuoyu Li

Cell Death Dis. 2019 Aug; 10(8): 593. Published online 2019 Aug 7. doi: 10.1038/s41419-019-1825-5

PMCID:: PMC6685981

Abstract Article PDF–10M

Select item 50083924.

DDX3 enhances oncogenic KRAS-induced tumor invasion in colorectal cancer via the β-catenin/ZEB1 axis

De-Wei Wu, Po-Lin Lin, Ya-Wen Cheng, Chi-Chou Huang, Lee Wang, Huei Lee

Oncotarget. 2016 Apr 19; 7(16): 22687–22699. Published online 2016 Mar 17. doi: 10.18632/oncotarget.8143

PMCID:: PMC5008392

Abstract Article PDF–5.9M

Select item 46219135.

DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer

Chia-Yi Su, Tsung-Chieh Lin, Yuan-Feng Lin, Ming-Huang Chen, Chien-Hsin Lee, Hsuan-Yao Wang, Yu-Chieh Lee, Yu-Peng Liu, Chi-Long Chen, Michael Hsiao

Oncotarget. 2015 Jul 30; 6(21): 18602–18612. Published online 2015 Jun 2. doi: 10.18632/oncotarget.4329

PMCID:: PMC4621913

Abstract Article PDF–4.2M

Select item 44120776.

Ketorolac salt is a newly discovered DDX3 inhibitor to treat oral cancer

Sabindra K. Samal, Samapika Routray, Ganesh Kumar Veeramachaneni, Rupesh Dash, Mahendran Botlagunta

Sci Rep. 2015; 5: 9982. Published online 2015 Apr 28. doi: 10.1038/srep09982

PMCID:: PMC4412077

Abstract Article PDF–744K

Select item 30934057.

A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication

Anna Garbelli, Sandra Beermann, Giulia Di Cicco, Ursula Dietrich, Giovanni Maga

PLoS One. 2011; 6(5): e19810. Published online 2011 May 12. doi: 10.1371/journal.pone.0019810

PMCID:: PMC3093405

Abstract Article PDF–940K

Select item 1040428.

Hepatitis C Virus Core Protein Interacts with Cellular Putative RNA Helicase

Li-Ru You, Chun-Ming Chen, Tien-Shun Yeh, Tzung-Yuan Tsai, Ru-Tsun Mai, Chi-Hung Lin, Yan-Hwa Wu Lee

J Virol. 1999 Apr; 73(4): 2841–2853. doi: 10.1128/jvi.73.4.2841-2853.1999

PMCID:: PMC104042

Abstract Article PDF–2.1M

Select item 50104689.

RNA remodeling activity of DEAD-box proteins tuned by protein concentration, RNA length and ATP

Younghoon Kim, Sua Myong

Mol Cell. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Mol Cell. 2016 Sep 1; 63(5): 865–876. Published online 2016 Aug 18. doi: 10.1016/j.molcel.2016.07.010

PMCID:: PMC5010468

Abstract Article PDF–2.8M

Select item 457324410.

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

Lot Snijders Blok, Erik Madsen, Jane Juusola, Christian Gilissen, Diana Baralle, Margot R.F. Reijnders, Hanka Venselaar, Céline Helsmoortel, Megan T. Cho, Alexander Hoischen, Lisenka E.L.M. Vissers, Tom S. Koemans, Willemijn Wissink-Lindhout, Evan E. Eichler, Corrado Romano, Hilde Van Esch, Connie Stumpel, Maaike Vreeburg, Eric Smeets, Karin Oberndorff, Bregje W.M. van Bon, Marie Shaw, Jozef Gecz, Eric Haan, Melanie Bienek, Corinna Jensen, Bart L. Loeys, Anke Van Dijck, A. Micheil Innes, Hilary Racher, Sascha Vermeer, Nataliya Di Donato, Andreas Rump, Katrina Tatton-Brown, Michael J. Parker, Alex Henderson, Sally A. Lynch, Alan Fryer, Alison Ross, Pradeep Vasudevan, Usha Kini, Ruth Newbury-Ecob, Kate Chandler, Alison Male, the DDD Study, Sybe Dijkstra, Jolanda Schieving, Jacques Giltay, Koen L.I. van Gassen, Janneke Schuurs-Hoeijmakers, Perciliz L. Tan, Igor Pediaditakis, Stefan A. Haas, Kyle Retterer, Patrick Reed, Kristin G. Monaghan, Eden Haverfield, Marvin Natowicz, Angela Myers, Michael C. Kruer, Quinn Stein, Kevin A. Strauss, Karlla W. Brigatti, Katherine Keating, Barbara K. Burton, Katherine H. Kim, Joel Charrow, Jennifer Norman, Audrey Foster-Barber, Antonie D. Kline, Amy Kimball, Elaine Zackai, Margaret Harr, Joyce Fox, Julie McLaughlin, Kristin Lindstrom, Katrina M. Haude, Kees van Roozendaal, Han Brunner, Wendy K. Chung, R. Frank Kooy, Rolph Pfundt, Vera Kalscheuer, Sarju G. Mehta, Nicholas Katsanis, Tjitske Kleefstra

Am J Hum Genet. 2015 Aug 6; 97(2): 343–352. doi: 10.1016/j.ajhg.2015.07.004

PMCID:: PMC4573244

Abstract Article PDF–1.3M

Select item 297637111.

DDX3 Regulates Cell Growth through Translational Control of Cyclin E1

Ming-Chih Lai, Wen-Cheng Chang, Sheau-Yann Shieh, Woan-Yuh Tarn

Mol Cell Biol. 2010 Nov; 30(22): 5444–5453. Published online 2010 Sep 13. doi: 10.1128/MCB.00560-10

PMCID:: PMC2976371

Abstract Article PDF–1.6M

Select item 294147012.

Hepatitis C Virus Core-Derived Peptides Inhibit Genotype 1b Viral Genome Replication via Interaction with DDX3X

Chaomin Sun, Cara T. Pager, Guangxiang Luo, Peter Sarnow, Jamie H. D. Cate

PLoS One. 2010; 5(9): e12826. Published online 2010 Sep 17. doi: 10.1371/journal.pone.0012826

PMCID:: PMC2941470

Abstract Article PDF–1006K

Select item 599804713.

The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity

P. Doñate-Macián, J. Jungfleisch, G. Pérez-Vilaró, F. Rubio-Moscardo, A. Perálvarez-Marín, J. Diez, M. A. Valverde

Nat Commun. 2018; 9: 2307. Published online 2018 Jun 13. doi: 10.1038/s41467-018-04776-7

PMCID:: PMC5998047

Abstract Article PDF–3.6M

Select item 565382114.

DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression

Pauline Adjibade, Valérie Grenier St-Sauveur, Jonathan Bergeman, Marc-Etienne Huot, Edouard W. Khandjian, Rachid Mazroui

Sci Rep. 2017; 7: 13832. Published online 2017 Oct 23. doi: 10.1038/s41598-017-14262-7

PMCID:: PMC5653821

Abstract Article PDF–1.9M

Select item 557335115.

DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression

Wei-Ju Chen, Wei-Ting Wang, Tsung-Yuan Tsai, Hao-Kang Li, Yan-Hwa Wu Lee

Sci Rep. 2017; 7: 9411. Published online 2017 Aug 25. doi: 10.1038/s41598-017-09779-w

PMCID:: PMC5573351

Abstract Article PDF–15M

Select item 506334716.

The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription

Nian Xiang, Miao He, Musarat Ishaq, Yu Gao, Feifei Song, Liang Guo, Li Ma, Guihong Sun, Dan Liu, Deyin Guo, Yu Chen

PLoS One. 2016; 11(10): e0164471. Published online 2016 Oct 13. doi: 10.1371/journal.pone.0164471

PMCID:: PMC5063347

Abstract Article PDF–3.4M

Select item 336717517.

The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes

Rene Geissler, Ralph P. Golbik, Sven-Erik Behrens

Nucleic Acids Res. 2012 Jun; 40(11): 4998–5011. Published online 2012 Feb 9. doi: 10.1093/nar/gks070

PMCID:: PMC3367175

Abstract Article PDF–4.1M

Select item 344227218.

DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

Ricardo Soto-Rifo, Paulina S Rubilar, Taran Limousin, Sylvain de Breyne, Didier Décimo, Théophile Ohlmann

EMBO J. 2012 Sep 12; 31(18): 3745–3756. Published online 2012 Aug 7. doi: 10.1038/emboj.2012.220

PMCID:: PMC3442272

Abstract Article PDF–697K

Select item 251689019.

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

Martina Schröder, Marcin Baran, Andrew G Bowie

EMBO J. 2008 Aug 6; 27(15): 2147–2157. Published online 2008 Jul 17. doi: 10.1038/emboj.2008.143

PMCID:: PMC2516890

Abstract Article PDF–1.4M

Select item 526973320.

RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP

Tsung-Yuan Tsai, Wei-Ting Wang, Hao-Kang Li, Wei-Ju Chen, Yu-Hong Tsai, Chi-Hong Chao, Yan-Hwa Wu Lee

Sci Rep. 2017; 7: 41452. Published online 2017 Jan 27. doi: 10.1038/srep41452

PMCID:: PMC5269733

Abstract Article PDF–2.2M

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