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Select item 82118521.

3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia

Lu Yang, Fengling Chen, Haichuan Zhu, Yang Chen, Bingjie Dong, Minglei Shi, Weitao Wang, Qian Jiang, Leping Zhang, Xiaojun Huang, Michael Q. Zhang, Hong Wu

Nat Commun. 2021; 12: 3708. Published online 2021 Jun 17. doi: 10.1038/s41467-021-24044-5

PMCID:: PMC8211852

Abstract Article PDF–4.6M

Select item 81698562.

IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R

Chenyang Qiao, Wenjie Huang, Jie Chen, Weibo Feng, Tongyue Zhang, Yijun Wang, Danfei Liu, Xiaoyu Ji, Meng Xie, Mengyu Sun, Daiming Fan, Kaichun Wu, Limin Xia

Cell Death Dis. 2021 Jun; 12(6): 564. Published online 2021 Jun 1. doi: 10.1038/s41419-021-03833-2

PMCID:: PMC8169856

Abstract Article PDF–6.1M

Select item 60266153.

Downregulation of HOXA13 sensitizes human esophageal squamous cell carcinoma to chemotherapy

Qi Shi, Luyan Shen, Bin Dong, Hao Fu, Xiaozheng Kang, Liang Dai, Yongbo Yang, Wanpu Yan, Ke‐Neng Chen

Thorac Cancer. 2018 Jul; 9(7): 836–846. Published online 2018 May 14. doi: 10.1111/1759-7714.12758

PMCID:: PMC6026615

Abstract Article PDF–1.3M

Select item 46950254.

HOXA13 is a potential GBM diagnostic marker and promotes glioma invasion by activating the Wnt and TGF-β pathways

Ran Duan, Lei Han, Qixue Wang, Jianwei Wei, Luyue Chen, Jianning Zhang, Chunsheng Kang, Lei Wang

Oncotarget. 2015 Sep 29; 6(29): 27778–27793. Published online 2015 Jul 31. doi: 10.18632/oncotarget.4813

PMCID:: PMC4695025

Abstract Article PDF–2.2M

Select item 28892425.

A novel mutation of HOXA13 in a family with hand-foot-genital syndrome and the role of polyalanine expansions in the spectrum of Müllerian fusion anomalies

Elisa M. Jorgensen, Jane I. Ruman, Leo Doherty, Hugh S. Taylor

Fertil Steril. Author manuscript; available in PMC 2011 Sep 1.

Published in final edited form as: Fertil Steril. 2010 Sep; 94(4): 1235–1238. Published online 2009 Jul 9. doi: 10.1016/j.fertnstert.2009.05.057

PMCID:: PMC2889242

Abstract Article PDF–63K

Select item 27044996.

Diminished vaginal HOXA13 expression in women with pelvic organ prolapse

Kathleen A. Connell, Marsha K. Guess, Alison Tate, Vaagn Andikyan, Richard Bercik, Hugh S. Taylor

Menopause. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Menopause. 2009; 16(3): 529–533. doi: 10.1097/gme.0b013e31818fb0c2

PMCID:: PMC2704499

Abstract Article PDF–433K

Select item 12870777.

Novel HOXA13 Mutations and the Phenotypic Spectrum of Hand-Foot-Genital Syndrome

Frances R. Goodman, Chiara Bacchelli, Angela F. Brady, Louise A. Brueton, Jean-Pierre Fryns, Douglas P. Mortlock, Jeffrey W. Innis, Lewis B. Holmes, Alan E. Donnenfeld, Murray Feingold, Frits A. Beemer, Raoul C. M. Hennekam, Peter J. Scambler

Am J Hum Genet. 2000 Jul; 67(1): 197–202. Published online 2000 Jun 5. doi: 10.1086/302961

PMCID:: PMC1287077

Abstract Article PDF–486K

Select item 103747588.

Long non-coding RNA HOTTIP exerts an oncogenic function by regulating HOXA13 in nasopharyngeal carcinoma

Huajun Feng, Feipeng Zhao, Jian Luo, Shengen Xu, Zhuoping Liang, Wei Xu, Yilin Bao, Gang Qin

Mol Biol Rep. 2023; 50(8): 6807–6818. Published online 2023 Jul 1. doi: 10.1007/s11033-023-08598-9

PMCID:: PMC10374758

Abstract Article PDF–712K

Select item 81847809.

HOXA13 in etiology and oncogenic potential of Barrett’s esophagus

Vincent T. Janmaat, Kateryna Nesteruk, Manon C. W. Spaander, Auke P. Verhaar, Bingting Yu, Rodrigo A. Silva, Wayne A. Phillips, Marcin Magierowski, Anouk van de Winkel, H. Scott Stadler, Tatiana Sandoval-Guzmán, Luc J. W. van der Laan, Ernst J. Kuipers, Ron Smits, Marco J. Bruno, Gwenny M. Fuhler, Nicholas J. Clemons, Maikel P. Peppelenbosch

Nat Commun. 2021; 12: 3354. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23641-8

PMCID:: PMC8184780

Abstract Article PDF–13M

Select item 754097910.

Serum exosomal microRNA‐766‐3p expression is associated with poor prognosis of esophageal squamous cell carcinoma

Shuang Liu, Zheng Lin, Zerong Zheng, Wenqing Rao, Yulan Lin, Huilin Chen, QianWen Xie, Yuanmei Chen, Zhijian Hu

Cancer Sci. 2020 Oct; 111(10): 3881–3892. Published online 2020 Aug 13. doi: 10.1111/cas.14550

PMCID:: PMC7540979

Abstract Article PDF–1.8M

Select item 437204511.

The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer

Zhihua Li, Xiaohui Zhao, Yu Zhou, Yimin Liu, Quanbo Zhou, Huilin Ye, YinXue Wang, Jinlong Zeng, Yadong Song, Wenchao Gao, ShangYou Zheng, Baoxiong Zhuang, Huimou Chen, Wenzhu Li, Haigang Li, Haifeng Li, Zhiqiang Fu, Rufu Chen

J Transl Med. 2015; 13: 84. Published online 2015 Mar 12. doi: 10.1186/s12967-015-0442-z

PMCID:: PMC4372045

Abstract Article PDF–8.6M

Select item 394375912.

lncRNA HOTTIP / HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients

Luca Quagliata, Matthias S. Matter, Salvatore Piscuoglio, Leila Arabi, Christian Ruiz, Alfredo Procino, Michal Kovac, Francesca Moretti, Zuzanna Makowska, Tujana Boldanova, Jesper B. Andersen, Monika Hämmerle, Luigi Tornillo, Markus H. Heim, Sven Diederichs, Clemente Cillo, Luigi M. Terracciano

Hepatology. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: Hepatology. 2014 Mar; 59(3): 911–923. Published online 2014 Jan 28. doi: 10.1002/hep.26740

PMCID:: PMC3943759

Abstract Article PDF–4.1M

Select item 173501113.

Severe digital abnormalities in a patient heterozygous for both a novel missense mutation in HOXD13 and a polyalanine tract expansion in HOXA13

P Debeer, C Bacchelli, P Scambler, L De Smet, J Fryns, F Goodman

J Med Genet. 2002 Nov; 39(11): 852–856. doi: 10.1136/jmg.39.11.852

PMCID:: PMC1735011

Summary PDF–172K

Select item 1073994814.

Hsa-microRNA-1249-3p/Homeobox A13 axis modulates the expression of β-catenin gene in human epithelial cells

Chiara Mazziotta, Maria Rosa Iaquinta, Maria Letizia Tramarin, Giada Badiale, Christian Felice Cervellera, Giulia Tonnini, Simone Patergnani, Paolo Pinton, Giovanni Lanza, Roberta Gafà, Mauro Tognon, Fernanda Martini, Monica De Mattei, John Charles Rotondo

Sci Rep. 2023; 13: 22872. Published online 2023 Dec 18. doi: 10.1038/s41598-023-49837-0

PMCID:: PMC10739948

Abstract Article PDF–3.7M

Select item 1041540415.

HOXA13 promotes the proliferation, migration, and invasion of nasopharyngeal carcinoma HNE1 cells by upregulating the expression of Snail and MMP-2

Jinping Liu, Huajun Feng, Dingting Wang, Yuanyuan Wang, Jian Luo, Shengen Xu, Feipeng Zhao, Gang Qin

Sci Rep. 2023; 13: 12978. Published online 2023 Aug 10. doi: 10.1038/s41598-023-40041-8

PMCID:: PMC10415404

Abstract Article PDF–5.4M

Select item 1017633016.

Conclusion of diagnostic odysseys due to inversions disrupting GLI3 and FBN1

Alistair T Pagnamenta, Jing Yu, Julie Evans, Philip Twiss, Genomics England Research Consortium, Musculoskeletal GeCIP MDT, Amaka C Offiah, Mohamed Wafik, Sarju G Mehta, Mohammed K Javaid, Sarah F Smithson, Jenny C Taylor

J Med Genet. 2023 May; 60(5): 505–510. Published online 2022 Nov 21. doi: 10.1136/jmg-2022-108753

PMCID:: PMC10176330

Abstract Article PDF–3.6M

Select item 509498217.

Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer

Sophie S.W. Wang, Kenly Wuputra, Chung-Jung Liu, Yin-Chu Lin, Yi-Ting Chen, Chee-Yin Chai, Chen-Lung Steve Lin, Kung-Kai Kuo, Ming-Ho Tsai, Shin-Wei Wang, Ker-Kong Chen, Hiroyuki Miyoshi, Yukio Nakamura, Shigeo Saito, Tadashi Hanafusa, Deng-Chyang Wu, Chang-Shen Lin, Kazunari K. Yokoyama

Oncotarget. 2016 Jun 14; 7(24): 36049–36064. Published online 2016 Apr 29. doi: 10.18632/oncotarget.9102

PMCID:: PMC5094982

Abstract Article PDF–12M

Select item 314825018.

Structural Basis for Sequence Specific DNA Binding and Protein Dimerization of HOXA13

Yonghong Zhang, Christine A. Larsen, H. Scott Stadler, James B. Ames

PLoS One. 2011; 6(8): e23069. Published online 2011 Aug 1. doi: 10.1371/journal.pone.0023069

PMCID:: PMC3148250

Abstract Article PDF–826K

Select item 221669019.

A dermal HOX transcriptional program regulates site-specific epidermal fate

John L. Rinn, Jordon K. Wang, Nancy Allen, Samantha A. Brugmann, Amanda J. Mikels, Helen Liu, Todd W. Ridky, H. Scott Stadler, Roel Nusse, Jill A. Helms, Howard Y. Chang

Genes Dev. 2008 Feb 1; 22(3): 303–307. doi: 10.1101/gad.1610508

PMCID:: PMC2216690

Abstract Article PDF–465K

Select item 278155020.

Global MYCN Transcription Factor Binding Analysis in Neuroblastoma Reveals Association with Distinct E-Box Motifs and Regions of DNA Hypermethylation

Derek M. Murphy, Patrick G. Buckley, Kenneth Bryan, Sudipto Das, Leah Alcock, Niamh H. Foley, Suzanne Prenter, Isabella Bray, Karen M. Watters, Desmond Higgins, Raymond L. Stallings

PLoS One. 2009; 4(12): e8154. Published online 2009 Dec 4. doi: 10.1371/journal.pone.0008154

PMCID:: PMC2781550

Abstract Article PDF–500K

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