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Select item 95904721.

Immunosuppression Induced by Brain-Specific HDAC6 Knockdown Improves Aging Performance in Drosophila melanogaster

Yingying Zhao, Hongwen Xuan, Chao Shen, Peiyi Liu, Jing-Dong J. Han, Wei Yu

Phenomics. 2022 Jun; 2(3): 194–200. Published online 2022 Feb 23. doi: 10.1007/s43657-022-00045-2

PMCID:: PMC9590472

Abstract Article PDF–1.3M

Select item 77372022.

Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration

Haolin Zhang, Bhanu Chandra Karisetty, Akanksha Bhatnagar, Ellen M. Armour, Mariah Beaver, Tiffany V. Roach, Sina Mortazavi, Shreya Mandloi, Felice Elefant

Mol Cell Neurosci. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Mol Cell Neurosci. 2020 Dec; 109: 103570. Published online 2020 Nov 4. doi: 10.1016/j.mcn.2020.103570

PMCID:: PMC7737202

Abstract Article PDF–2.7M

Select item 43753913.

Animal and in silico models for the study of sarcomeric cardiomyopathies

Dirk J. Duncker, Jeroen Bakkers, Bianca J. Brundel, Jeff Robbins, Jil C. Tardiff, Lucie Carrier

Cardiovasc Res. 2015 Apr 1; 105(4): 439–448. Published online 2015 Jan 19. doi: 10.1093/cvr/cvv006

PMCID:: PMC4375391

Abstract Article PDF–306K

Select item 32846894.

Loss of Proteostatic Control as a Substrate for Atrial Fibrillation: A Novel Target for Upstream Therapy by Heat Shock Proteins

Roelien A. M. Meijering, Deli Zhang, Femke Hoogstra-Berends, Robert H. Henning, Bianca J. J. M. Brundel

Front Physiol. 2012; 3: 36. Published online 2012 Feb 23. doi: 10.3389/fphys.2012.00036

PMCID:: PMC3284689

Abstract Article PDF–1.1M

Select item 28371695.

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

Joo-Yong Lee, Hiroshi Koga, Yoshiharu Kawaguchi, Waixing Tang, Esther Wong, Ya-Sheng Gao, Udai B Pandey, Susmita Kaushik, Emily Tresse, Jianrong Lu, J Paul Taylor, Ana Maria Cuervo, Tso-Pang Yao

EMBO J. 2010 Mar 3; 29(5): 969–980. Published online 2010 Jan 14. doi: 10.1038/emboj.2009.405

PMCID:: PMC2837169

Abstract Article PDF–2.8M

Select item 69200296.

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

Aviel Even, Giovanni Morelli, Loïc Broix, Chiara Scaramuzzino, Silvia Turchetto, Ivan Gladwyn-Ng, Romain Le Bail, Michal Shilian, Stephen Freeman, Maria M. Magiera, A. S. Jijumon, Nathalie Krusy, Brigitte Malgrange, Bert Brone, Paula Dietrich, Ioannis Dragatsis, Carsten Janke, Frédéric Saudou, Miguel Weil, Laurent Nguyen

Sci Adv. 2019 Dec; 5(12): eaax2705. Published online 2019 Dec 18. doi: 10.1126/sciadv.aax2705

PMCID:: PMC6920029

Abstract Article PDF–1.6M

Select item 56654527.

Increased acetylation of microtubules rescues human tau-induced microtubule defects and neuromuscular junction abnormalities in Drosophila

Chuan-Xi Mao, Xue Wen, Shan Jin, Yong Q. Zhang

Dis Model Mech. 2017 Oct 1; 10(10): 1245–1252. doi: 10.1242/dmm.028316

PMCID:: PMC5665452

Abstract Article

Select item 42080978.

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

Vinay K. Godena, Nicholas Brookes-Hocking, Annekathrin Moller, Gary Shaw, Matthew Oswald, Rosa M. Sancho, Christopher C. J. Miller, Alexander J. Whitworth, Kurt J. De Vos

Nat Commun. 2014 Oct 15; 5: 5245. Published online 2014 Oct 15. doi: 10.1038/ncomms6245

PMCID:: PMC4208097

Abstract Article PDF–7.5M

Select item 33375949.

Drosophila Answers to TDP-43 Proteinopathies

Maurizio Romano, Fabian Feiguin, Emanuele Buratti

J Amino Acids. 2012; 2012: 356081. Published online 2012 Apr 18. doi: 10.1155/2012/356081

PMCID:: PMC3337594

Abstract Article PDF–1.0M

Select item 289397810.

Drosophila Histone Deacetylase 6 Protects Dopaminergic Neurons against α-Synuclein Toxicity by Promoting Inclusion Formation

Guiping Du, Xiang Liu, Xinping Chen, Mei Song, Yan Yan, Renjie Jiao, Chih-chen Wang

Mol Biol Cell. 2010 Jul 1; 21(13): 2128–2137. doi: 10.1091/mbc.E10-03-0200

PMCID:: PMC2893978

Abstract Article PDF–3.0M

Select item 300035911.

Histone Deacetylases Suppress CGG Repeat–Induced Neurodegeneration Via Transcriptional Silencing in Models of Fragile X Tremor Ataxia Syndrome

Peter K. Todd, Seok Yoon Oh, Amy Krans, Udai B. Pandey, Nicholas A. Di Prospero, Kyung-Tai Min, J. Paul Taylor, Henry L. Paulson

PLoS Genet. 2010 Dec; 6(12): e1001240. Published online 2010 Dec 9. doi: 10.1371/journal.pgen.1001240

PMCID:: PMC3000359

Abstract Article PDF–5.4M

Select item 884398712.

Acetylated α-tubulin K394 regulates microtubule stability to shape the growth of axon terminals

Harriet A. J. Saunders, Dena M. Johnson-Schlitz, Brian V. Jenkins, Peter J. Volkert, Sihui Z. Yang, Jill Wildonger

Curr Biol. Author manuscript; available in PMC 2023 Feb 7.

Published in final edited form as: Curr Biol. 2022 Feb 7; 32(3): 614–630.e5. Published online 2022 Jan 25. doi: 10.1016/j.cub.2021.12.012

PMCID:: PMC8843987

Abstract Article PDF–3.1M

Select item 1012117413.

CBP and Gcn5 drive zygotic genome activation independently of their catalytic activity

Filippo Ciabrelli, Leily Rabbani, Francesco Cardamone, Fides Zenk, Eva Löser, Melanie A. Schächtle, Marina Mazina, Vincent Loubiere, Nicola Iovino

Sci Adv. 2023 Apr; 9(16): eadf2687. Published online 2023 Apr 21. doi: 10.1126/sciadv.adf2687

PMCID:: PMC10121174

Abstract Article PDF–1.6M

Select item 758844514.

Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases

Mariah Beaver, Akanksha Bhatnagar, Priyalakshmi Panikker, Haolin Zhang, Renee Snook, Visha Parmar, Gayathri Vijayakumar, Niteesha Betini, Sunya Akhter, Felice Elefant

Sci Rep. 2020; 10: 18265. Published online 2020 Oct 26. doi: 10.1038/s41598-020-75035-3

PMCID:: PMC7588445

Abstract Article PDF–2.9M

Select item 538706115.

The Role of Histone Deacetylase 6 in Synaptic Plasticity and Memory

Sarah Perry, Beril Kiragasi, Dion Dickman, Anandasankar Ray

Cell Rep. Author manuscript; available in PMC 2017 Apr 11.

Published in final edited form as: Cell Rep. 2017 Feb 7; 18(6): 1337–1345. doi: 10.1016/j.celrep.2017.01.028

PMCID:: PMC5387061

Abstract Article PDF–1.3M

Select item 280837216.

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

Fabienne C Fiesel, Aaron Voigt, Stephanie S Weber, Chris Van den Haute, Andrea Waldenmaier, Karin Görner, Michael Walter, Marlene L Anderson, Jeannine V Kern, Tobias M Rasse, Thorsten Schmidt, Wolfdieter Springer, Roland Kirchner, Michael Bonin, Manuela Neumann, Veerle Baekelandt, Marianna Alunni-Fabbroni, Jörg B Schulz, Philipp J Kahle

EMBO J. 2010 Jan 6; 29(1): 209–221. Published online 2009 Nov 12. doi: 10.1038/emboj.2009.324

PMCID:: PMC2808372

Abstract Article PDF–1.2M

Select item 258143117.

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

Judit Pallos, Laszlo Bodai, Tamas Lukacsovich, Judith M. Purcell, Joan S. Steffan, Leslie Michels Thompson, J. Lawrence Marsh

Hum Mol Genet. 2008 Dec 1; 17(23): 3767–3775. Published online 2008 Sep 1. doi: 10.1093/hmg/ddn273

PMCID:: PMC2581431

Abstract Article PDF–328K

Select item 360698118.

HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila

Ying Xiong, Kai Zhao, Jiaxi Wu, Zhiheng Xu, Shan Jin, Yong Q. Zhang

Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12): 4604–4609. Published online 2013 Mar 4. doi: 10.1073/pnas.1207586110

PMCID:: PMC3606981

Abstract Article PDF–1.2M

Select item 700091719.

The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration

Ernest J. Monahan Vargas, Andrew J. Matamoros, Jingyun Qiu, Calvin H. Jan, Qin Wang, David Gorczyca, Tina W. Han, Jonathan S. Weissman, Yuh Nung Jan, Swati Banerjee, Yuanquan Song

Genes Dev. 2020 Feb 1; 34(3-4): 194–208. doi: 10.1101/gad.331330.119

PMCID:: PMC7000917

Abstract Article PDF–16M

Select item 631455220.

ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion

Ruoxi Wang, Jieqiong Tan, Tingting Chen, Hailong Han, Runyi Tian, Ya Tan, Yiming Wu, Jingyi Cui, Fang Chen, Jie Li, Lu Lv, Xinjie Guan, Shuai Shang, Jiahong Lu, Zhuohua Zhang

J Cell Biol. 2019 Jan 7; 218(1): 267–284. doi: 10.1083/jcb.201804165