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Select item 91046191.

Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice

Taija Heinosalo, Kalle T. Rytkönen, Niina Saarinen, Päivi Järvensivu, Pauliina Damdimopoulou, Leena Strauss, Satu Orasniemi, Petricia Horshauge, Michael Gabriel, Pasi Koskimies, Claes Ohlsson, Pauliina Kronqvist, Matti Poutanen

Int J Mol Sci. 2022 May; 23(9): 4815. Published online 2022 Apr 27. doi: 10.3390/ijms23094815

PMCID:: PMC9104619

Abstract Article PDF–2.5M

Select item 71700452.

Altered expression of 17-β-hydroxysteroid dehydrogenase type 2 and its prognostic significance in non-small cell lung cancer

Hanna Drzewiecka, Donata Jarmołowska-Jurczyszyn, Andrzej Kluk, Bartłomiej Gałęcki, Wojciech Dyszkiewicz, Paweł P. Jagodziński

Int J Oncol. 2020 Jun; 56(6): 1352–1372. Published online 2020 Mar 19. doi: 10.3892/ijo.2020.5014

PMCID:: PMC7170045

Abstract Article PDF–1.2M

Select item 71414003.

Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease

Panu K. Luukkonen, Taru Tukiainen, Anne Juuti, Henna Sammalkorpi, P.A. Nidhina Haridas, Onni Niemelä, Johanna Arola, Marju Orho-Melander, Antti Hakkarainen, Petri T. Kovanen, Om Dwivedi, Leif Groop, Leanne Hodson, Amalia Gastaldelli, Tuulia Hyötyläinen, Matej Orešič, Hannele Yki-Järvinen

JCI Insight. 2020 Mar 12; 5(5): e132158. Published online 2020 Mar 12. doi: 10.1172/jci.insight.132158

PMCID:: PMC7141400

Abstract Article PDF–1.6M

Select item 66496864.

Current knowledge of the multifunctional 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1)

Wanhong He, Misra Gauri, Tang Li, Ruixuan Wang, Sheng-Xiang Lin

Gene. Author manuscript; available in PMC 2019 Jul 23.

Published in final edited form as: Gene. 2016 Aug 15; 588(1): 54–61. Published online 2016 Apr 19. doi: 10.1016/j.gene.2016.04.031

PMCID:: PMC6649686

Article PDF–1.0M

Select item 54450485.

Involvement of 17β-hydroxysteroid dehydrogenase type gene 1 937 A>G polymorphism in infertility in Polish Caucasian women with endometriosis

Maciej Osiński, Adrianna Mostowska, Przemyslaw Wirstlein, Jana Skrzypczak, Paweł Piotr Jagodziński, Malgorzata Szczepańska

J Assist Reprod Genet. 2017 Jun; 34(6): 789–794. Published online 2017 Apr 12. doi: 10.1007/s10815-017-0911-9

PMCID:: PMC5445048

Abstract Article PDF–306K

Select item 54175356.

17β-Hydroxysteroid Dehydrogenase Type 1 Stimulates Breast Cancer by Dihydrotestosterone Inactivation in Addition to Estradiol Production

Juliette A. Aka, Mausumi Mazumdar, Chang-Qing Chen, Donald Poirier, Sheng-Xiang Lin

Mol Endocrinol. April 1, 2010; 24(4): 832–845. doi: 10.1210/me.2009-0468

PMCID:: PMC5417535

Abstract Article

Select item 45258127.

Association between HSD17B1 rs605059 polymorphisms and the risk of uterine diseases: a systemic review and meta-analysis

Xiyan Mu, Xue Du, Kui Yao, Jitong Zhao, Ce Bian, Qiao Wang, Hongwei Ma, Tao Yi, Yang Wu, Xia Zhao

Int J Clin Exp Pathol. 2015; 8(6): 6012–6018. Published online 2015 Jun 1.

PMCID:: PMC4525812

Abstract Article PDF–339K

Select item 38808978.

Gonadal status-dependent effects of in vivo β-estradiol administration to female rats on in vitro epileptiform activity induced by low [Mg²⁺]_o in combined hippocampus-entorhinal cortex slices

Jana Velíšková, Libor Velíšek

Epilepsy Res. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Epilepsy Res. 2013 Dec; 107(3): 10.1016/j.eplepsyres.2013.09.002. Published online 2013 Sep 20. doi: 10.1016/j.eplepsyres.2013.09.002

PMCID:: PMC3880897

Abstract Article PDF–160K

Select item 37247099.

Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor

Mohit K Verma, Yasuhiro Miki, Keiko Abe, Takashi Suzuki, Hiromichi Niikawa, Satoshi Suzuki, Takashi Kondo, Hironobu Sasano

J Transl Med. 2013; 11: 167. Published online 2013 Jul 9. doi: 10.1186/1479-5876-11-167

PMCID:: PMC3724709

Abstract Article PDF–1.9M

Select item 344635510.

17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration

Juliette A Aka, Mouna Zerradi, François Houle, Jacques Huot, Sheng-Xiang Lin

Breast Cancer Res. 2012; 14(3): R92. Published online 2012 Jun 12. doi: 10.1186/bcr3207

PMCID:: PMC3446355

Abstract Article PDF–1.3M

Select item 325379111.

The Contribution of 17beta-Hydroxysteroid Dehydrogenase Type 1 to the Estradiol-Estrone Ratio in Estrogen-Sensitive Breast Cancer Cells

Chen-Yan Zhang, Jiong Chen, Da-Chuan Yin, Sheng-Xiang Lin

PLoS One. 2012; 7(1): e29835. Published online 2012 Jan 9. doi: 10.1371/journal.pone.0029835

PMCID:: PMC3253791

Abstract Article PDF–446K

Select item 315347812.

Structural Basis for Species Specific Inhibition of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1): Computational Study and Biological Validation

Tobias Klein, Claudia Henn, Matthias Negri, Martin Frotscher

PLoS One. 2011; 6(8): e22990. Published online 2011 Aug 9. doi: 10.1371/journal.pone.0022990

PMCID:: PMC3153478

Abstract Article PDF–841K

Select item 290871713.

HSD17B1 genetic variants and hormone receptor-defined breast cancer

Mia M. Gaudet, Stephen Chanock, Alison Dunning, Kristy Driver, Louise A. Brinton, Jolanta Lissowska, Beata Peplonska, Paul Pharoah, Montserrat Garcia-Closas

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 Jul 22.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Oct; 17(10): 2766–2772. doi: 10.1158/1055-9965.EPI-07-2891

PMCID:: PMC2908717

Abstract Article PDF–572K

Select item 264502214.

Enhanced cortisol production rates, free cortisol, and 11β-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss

Jonathan Q. Purnell, Steven E. Kahn, Mary H. Samuels, David Brandon, D. Lynn Loriaux, John D. Brunzell

Am J Physiol Endocrinol Metab. 2009 Feb; 296(2): E351–E357. Published online 2008 Dec 2. doi: 10.1152/ajpendo.90769.2008

PMCID:: PMC2645022

Abstract Article

Select item 223867915.

Interaction of soy and 17β-HSD1 gene polymorphisms in the risk of endometrial cancer

Qi Dai, Wang-Hong Xu, Ji-Rong Long, Regina Courtney, Yong-Bing Xiang, Qiuyin Cai, Jiarong Cheng, Wei Zheng, Xiao-Ou Shu

Pharmacogenet Genomics. Author manuscript; available in PMC 2008 Feb 11.

Published in final edited form as: Pharmacogenet Genomics. 2007 Feb; 17(2): 161–167. doi: 10.1097/FPC.0b013e32801112a1

PMCID:: PMC2238679

Abstract Article PDF–345K

Select item 128795516.

Genetic Variation in the HSD17B1 Gene and Risk of Prostate Cancer

Peter Kraft, Paul Pharoah, Stephen J Chanock, Demetrius Albanes, Laurence N Kolonel, Richard B Hayes, David Altshuler, Gerald Andriole, Christine Berg, Heiner Boeing, Noel P Burtt, Bas Bueno-de-Mesquita, Eugenia E Calle, Howard Cann, Federico Canzian, Yen-Ching Chen, David E Crawford, Alison M Dunning, Heather S Feigelson, Matthew L Freedman, John M Gaziano, Ed Giovannucci, Carlos Alberto Gonzalez, Christopher A Haiman, Goran Hallmans, Brian E Henderson, Joel N Hirschhorn, David J Hunter, Rudolf Kaaks, Timothy Key, Loic Le Marchand, Jing Ma, Kim Overvad, Domenico Palli, Malcolm C Pike, Elio Riboli, Carmen Rodriguez, Wendy V Setiawan, Meir J Stampfer, Daniel O Stram, Gilles Thomas, Michael J Thun, Ruth Travis, Antonia Trichopoulou, Jarmo Virtamo, Sholom Wacholder

PLoS Genet. 2005 Nov; 1(5): e68. Published online 2005 Nov 25. doi: 10.1371/journal.pgen.0010068

PMCID:: PMC1287955

Abstract Article PDF–192K

Select item 1531217.

Structure of the ternary complex of human 17β-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP⁺

Mark W. Sawicki, Mary Erman, Terhi Puranen, Pirkko Vihko, Debashis Ghosh

Proc Natl Acad Sci U S A. 1999 Feb 2; 96(3): 840–845. doi: 10.1073/pnas.96.3.840

PMCID:: PMC15312

Abstract Article PDF–701K

Select item 857785818.

Steroid Metabolism in Children and Adolescents With Obesity and Insulin Resistance: Altered SRD5A and 20α/20βHSD Activity

Marta Sumińska, Rafał Podgórski, Piotr Fichna, Marta Fichna

Front Endocrinol (Lausanne) 2021; 12: 759971. Published online 2021 Oct 26. doi: 10.3389/fendo.2021.759971

PMCID:: PMC8577858

Abstract Article PDF–381K

Select item 403046119.

Immunoexpression of aromatase cytochrome P450 and 17β-hydroxysteroid dehydrogenase in women’s ovaries after menopause

Agnieszka Brodowska, Jacek Brodowski, Maria Laszczyńska, Sylwia Słuczanowska-Głąbowska, Bogdan Rumianowski, Iwona Rotter, Andrzej Starczewski, Mariusz Z Ratajczak

J Ovarian Res. 2014; 7: 52. Published online 2014 May 10. doi: 10.1186/1757-2215-7-52

PMCID:: PMC4030461

Abstract Article PDF–1.4M

Select item 335707120.

Genetic polymorphisms and obesity influence estradiol decline during the menopause

MaryFran R. Sowers, John F. Randolph, Huiyong Zheng, Mary Jannausch, Daniel McConnell, Sharon R. Kardia, Carolyn J. Crandall, Bin Nan

Clin Endocrinol (Oxf) Author manuscript; available in PMC 2012 May 21.

Published in final edited form as: Clin Endocrinol (Oxf). 2011 May; 74(5): 618–623. doi: 10.1111/j.1365-2265.2010.03968.x

PMCID:: PMC3357071

Abstract Article PDF–490K

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