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Items: 1 to 20 of 54

1.
The 9-1-1 DNA clamp subunit RAD1 forms specific interactions with clamp loader RAD17, revealing functional implications for binding-protein RHINO
Kodai Hara, Asami Hishiki, Takako Hoshino, Kiho Nagata, Nao Iida, Yukimasa Sawada, Eiji Ohashi, Hiroshi Hashimoto
J Biol Chem. 2023 Apr; 299(4): 103061. Published online 2023 Feb 24. doi: 10.1016/j.jbc.2023.103061
PMCID:
PMC10060742
AbstractArticlePDF–2.0M
2.
Distinct Functional Consequences of MUTYH Variants associated with Colorectal Cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1
Megan K. Brinkmeyer, Sheila S. David
DNA Repair (Amst) Author manuscript; available in PMC 2016 Nov 7.
Published in final edited form as: DNA Repair (Amst). 2015 Oct; 34: 39–51. Published online 2015 Aug 12. doi: 10.1016/j.dnarep.2015.08.001
PMCID:
PMC5098423
AbstractArticlePDF–2.1M
3.
Association of the Rad9-Rad1-Hus1 Checkpoint Clamp with MYH DNA Glycosylase and DNA
Bor-Jang Hwang, Jin Jin, Randall Gunther, Amrita Madabushi, Guoli Shi, Gerald M. Wilson, A-Lien Lu
DNA Repair (Amst) Author manuscript; available in PMC 2016 Jul 1.
Published in final edited form as: DNA Repair (Amst). 2015 Jul; 31: 80–90. Published online 2015 May 16. doi: 10.1016/j.dnarep.2015.05.004
PMCID:
PMC4458174
AbstractArticlePDF–1.8M
4.
LOSS OF HUS1 SENSITIZES CELLS TO ETOPOSIDE-INDUCED APOPTOSIS BY REGULATING BH3-ONLY PROTEINS
C L Meyerkord, Y Takahashi, R Araya, N Takada, R Weiss, H-G Wang
Oncogene. Author manuscript; available in PMC 2009 Dec 11.
Published in final edited form as: Oncogene. 2008 Dec 11; 27(58): 7248–7259. Published online 2008 Sep 15. doi: 10.1038/onc.2008.336
PMCID:
PMC2605171
AbstractArticlePDF–3.2M
5.
In vivo miRNA knockout screening identifies miR-190b as a novel tumor suppressor
Hui Hong, Shun Yao, Yuanyuan Zhang, Yi Ye, Cheng Li, Liang Hu, Yihua Sun, Hsin-Yi Huang, Hongbin Ji
PLoS Genet. 2020 Nov; 16(11): e1009168. Published online 2020 Nov 2. doi: 10.1371/journal.pgen.1009168
PMCID:
PMC7660552
AbstractArticlePDF–2.9M
6.
Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp
Kodai Hara, Nao Iida, Ryota Tamafune, Eiji Ohashi, Hitomi Sakurai, Yoshinobu Ishikawa, Asami Hishiki, Hiroshi Hashimoto
J Biol Chem. 2020 Jan 24; 295(4): 899–904. Published online 2019 Nov 27. doi: 10.1074/jbc.AC119.011816
PMCID:
PMC6983850
AbstractArticlePDF–2.1M
7.
Intramolecular Binding of the Rad9 C Terminus in the Checkpoint Clamp Rad9-Hus1-Rad1 Is Closely Linked with Its DNA Binding
Yukimasa Takeishi, Rie Iwaya-Omi, Eiji Ohashi, Toshiki Tsurimoto
J Biol Chem. 2015 Aug 7; 290(32): 19923–19932. Published online 2015 Jun 18. doi: 10.1074/jbc.M115.669002
PMCID:
PMC4528151
AbstractArticlePDF–1.0M
8.
Differential Dynamics of ATR-Mediated Checkpoint Regulators
Daniël O. Warmerdam, Roland Kanaar, Veronique A. J. Smits
J Nucleic Acids. 2010; 2010: 319142. Published online 2010 Aug 17. doi: 10.4061/2010/319142
PMCID:
PMC2933903
AbstractArticlePDF–3.7M
9.
The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates NEIL1 glycosylase
Xin Guan, Haibo Bai, Guoli Shi, Corey A. Theriot, Tapas K. Hazra, Sankar Mitra, A-Lien Lu
Nucleic Acids Res. 2007 Apr; 35(8): 2463–2472. Published online 2007 Mar 29. doi: 10.1093/nar/gkm075
PMCID:
PMC1885643
AbstractArticlePDF–5.8M
10.
Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage.
C F Kostrub, K Knudsen, S Subramani, T Enoch
EMBO J. 1998 Apr 1; 17(7): 2055–2066. doi: 10.1093/emboj/17.7.2055
PMCID:
PMC1170550
SummaryPDF–596K
11.
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
Wensheng Wang, Patrick Brandt, Marie L. Rossi, Laura Lindsey-Boltz, Vladimir Podust, Ellen Fanning, Aziz Sancar, Robert A. Bambara
Proc Natl Acad Sci U S A. 2004 Nov 30; 101(48): 16762–16767. Published online 2004 Nov 19. doi: 10.1073/pnas.0407686101
PMCID:
PMC534749
AbstractArticlePDF–450K
12.
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase β and increases its DNA substrate utilisation efficiency: implications for DNA repair
Magali Toueille, Nazim El-Andaloussi, Isabelle Frouin, Raimundo Freire, Dorothee Funk, Igor Shevelev, Erica Friedrich-Heineken, Giuseppe Villani, Michael O. Hottiger, Ulrich Hübscher
Nucleic Acids Res. 2004; 32(11): 3316–3324. Published online 2004 Jun 22. doi: 10.1093/nar/gkh652
PMCID:
PMC443528
AbstractArticlePDF–378K
13.
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
Vladimir P. Bermudez, Laura A. Lindsey-Boltz, Anthony J. Cesare, Yoshimasa Maniwa, Jack D. Griffith, Jerard Hurwitz, Aziz Sancar
Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4): 1633–1638. Published online 2003 Feb 10. doi: 10.1073/pnas.0437927100
PMCID:
PMC149884
AbstractArticlePDF–324K
14.
The Human G2 Checkpoint Control Protein hRAD9 Is a Nuclear Phosphoprotein That Forms Complexes with hRAD1 and hHUS1
Robert P. St. Onge, Christian M. Udell, Richard Casselman, Scott Davey
Mol Biol Cell. 1999 Jun; 10(6): 1985–1995. doi: 10.1091/mbc.10.6.1985
PMCID:
PMC25401
AbstractArticlePDF–518K
15.
SUMO-1 modification of FEN1 facilitates its interaction with Rad9–Rad1–Hus1 to counteract DNA replication stress
Xiaoli Xu, Rongyi Shi, Li Zheng, Zhigang Guo, Liangyan Wang, Mian Zhou, Ye Zhao, Bing Tian, Khue Truong, Yuan Chen, Binghui Shen, Yuejin Hua, Hong Xu
J Mol Cell Biol. 2018 Oct; 10(5): 460–474. Published online 2018 Oct 15. doi: 10.1093/jmcb/mjy047
PMCID:
PMC6231531
AbstractArticlePDF–2.3M
16.
RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling
Laura A Lindsey-Boltz, Michael G Kemp, Christopher Capp, Aziz Sancar
Cell Cycle. 2015; 14(1): 99–108. Published online 2015 Jan 20. doi: 10.4161/15384101.2014.967076
PMCID:
PMC4614876
AbstractArticlePDF–620K
17.
Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability
Jordi Querol-Audí, Chunli Yan, Xiaojun Xu, Susan E. Tsutakawa, Miaw-Sheue Tsai, John A. Tainer, Priscilla K. Cooper, Eva Nogales, Ivaylo Ivanov
Proc Natl Acad Sci U S A. 2012 May 29; 109(22): 8528–8533. Published online 2012 May 14. doi: 10.1073/pnas.1121116109
PMCID:
PMC3365210
AbstractArticlePDF–888K
18.
The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1
Wei Song, John M. Pascal, Tom Ellenberger, Alan E. Tomkinson
DNA Repair (Amst) Author manuscript; available in PMC 2010 Aug 6.
Published in final edited form as: DNA Repair (Amst). 2009 Aug 6; 8(8): 912–919. Published online 2009 Jun 11. doi: 10.1016/j.dnarep.2009.05.002
PMCID:
PMC2759717
AbstractArticlePDF–431K
19.
Structure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint Complex
Min Xu, Lin Bai, Yong Gong, Wei Xie, Haiying Hang, Tao Jiang
J Biol Chem. 2009 Jul 31; 284(31): 20457–20461. Published online 2009 Jun 17. doi: 10.1074/jbc.C109.022384
PMCID:
PMC2742809
AbstractArticlePDF–1.4M
20.
Jab1 Mediates Protein Degradation of Rad9/Rad1/Hus1 Checkpoint Complex
Jin Huang, Honglin Yuan, Chongyuan Lu, Ximeng Liu, Xu Cao, Mei Wan
J Mol Biol. Author manuscript; available in PMC 2009 Jul 20.
Published in final edited form as: J Mol Biol. 2007 Aug 10; 371(2): 514–527. Published online 2007 Jun 4. doi: 10.1016/j.jmb.2007.05.095
PMCID:
PMC2712929
AbstractArticlePDF–4.7M

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