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Select item 104125431.

Race-specific association of an IRGM risk allele with cytokine expression in human subjects

Teminioluwa Ajayi, Prashant Rai, Min Shi, Kristin A. Gabor, Peer W. F. Karmaus, Julie M. Meacham, Kevin Katen, Jennifer H. Madenspacher, Shepherd H. Schurman, Michael B. Fessler

Sci Rep. 2023; 13: 12911. Published online 2023 Aug 9. doi: 10.1038/s41598-023-40313-3

PMCID:: PMC10412543

Abstract Article PDF–1.4M

Select item 99336302.

Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice

Kaley M. Wilburn, Rachel K. Meade, Emma M. Heckenberg, Jacob Dockterman, Jörn Coers, Christopher M. Sassetti, Andrew J. Olive, Clare M. Smith

Infect Immun. 2023 Feb; 91(2): e00510-22. Published online 2023 Jan 11. doi: 10.1128/iai.00510-22

PMCID:: PMC9933630

Abstract Article PDF–1.5M

Select item 65351153.

DR. Tracey G. Simon, Xuan Deng, Ching-Ti Liu, Raymond T. Chung, DR. Michelle T. Long

Liver Int. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Liver Int. 2019 Jun; 39(6): 1022–1026. Published online 2019 Feb 17. doi: 10.1111/liv.14039

PMCID:: PMC6535115

Abstract Article PDF–312K

Select item 63833774.

Crohn’s disease IRGM risk alleles are associated with altered gene expression in human tissues

Teminioluwa A. Ajayi, Cynthia L. Innes, Sara A. Grimm, Prashant Rai, Ryan Finethy, Jörn Coers, Xuting Wang, Douglas A. Bell, John A. McGrath, Shepherd H. Schurman, Michael B. Fessler

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1; 316(1): G95–G105. Published online 2018 Oct 18. doi: 10.1152/ajpgi.00196.2018

PMCID:: PMC6383377

Abstract Article

Select item 62305235.

IRGM Gene Variants Modify the Relationship Between Visceral Adipose Tissue and NAFLD in Patients With Crohn’s Disease

Tracey G Simon, Kimberley W J Van Der Sloot, Samantha B Chin, Amit D Joshi, Paul Lochhead, Ashwin N Ananthakrishnan, Ramnik Xavier, Raymond T Chung, Hamed Khalili

Inflamm Bowel Dis. 2018 Oct; 24(10): 2247–2257. Published online 2018 May 18. doi: 10.1093/ibd/izy128

PMCID:: PMC6230523

Abstract Article PDF–517K

Select item 60162176.

Polymorphisms in Autophagy-Related Gene IRGM Are Associated with Susceptibility to Autoimmune Thyroid Diseases

Qiu-ming Yao, Yuan-feng Zhu, Wen Wang, Zhen-yu Song, Xiao-qing Shao, Ling Li, Rong-hua Song, Xiao-fei An, Qiu Qin, Qian Li, Jin-an Zhang

Biomed Res Int. 2018; 2018: 7959707. Published online 2018 Jun 11. doi: 10.1155/2018/7959707

PMCID:: PMC6016217

Abstract Article PDF–701K

Select item 56718197.

Association between IRGM polymorphisms and tuberculosis risk: A meta-analysis

Haojun Xie, Chufang Li, Mincong Zhang, Nanshan Zhong, Ling Chen

Medicine (Baltimore) 2017 Oct; 96(43): e8189. Published online 2017 Oct 27. doi: 10.1097/MD.0000000000008189

PMCID:: PMC5671819

Abstract Article PDF–1.2M

Select item 43903418.

Coxsackievirus A16 Elicits Incomplete Autophagy Involving the mTOR and ERK Pathways

Yingying Shi, Xiaohua He, Guoguo Zhu, Huilin Tu, Zhongchun Liu, Wenhua Li, Song Han, Jun Yin, Biwen Peng, Wanhong Liu

PLoS One. 2015; 10(4): e0122109. Published online 2015 Apr 8. doi: 10.1371/journal.pone.0122109

PMCID:: PMC4390341

Abstract Article PDF–6.8M

Select item 41564159.

Association of IRGM Gene Mutations with Inflammatory Bowel Disease in the Indian Population

Kirankumar Baskaran, Srinivasan Pugazhendhi, Balakrishnan S. Ramakrishna

PLoS One. 2014; 9(9): e106863. Published online 2014 Sep 5. doi: 10.1371/journal.pone.0106863

PMCID:: PMC4156415

Abstract Article PDF–473K

Select item 395348810.

Tomonori Kimura, Eizo Watanabe, Teruo Sakamoto, Osamu Takasu, Toshiaki Ikeda, Kazumi Ikeda, Joji Kotani, Nobuya Kitamura, Tomohito Sadahiro, Yoshihisa Tateishi, Koichiro Shinozaki, Shigeto Oda

PLoS One. 2014; 9(3): e91522. Published online 2014 Mar 13. doi: 10.1371/journal.pone.0091522

PMCID:: PMC3953488

Abstract Article PDF–193K

Select item 382744011.

Association between Variants of the Autophagy Related Gene – IRGM and Susceptibility to Crohn’s Disease and Ulcerative Colitis: A Meta-Analysis

Xiao Cheng Lu, Yi Tao, Chen Wu, Peng Lai Zhao, Kai Li, Jin Yu Zheng, Li Xin Li

PLoS One. 2013; 8(11): e80602. Published online 2013 Nov 13. doi: 10.1371/journal.pone.0080602

PMCID:: PMC3827440

Abstract Article PDF–1.3M

Select item 355477712.

IRGM Variants and Susceptibility to Inflammatory Bowel Disease in the German Population

Jürgen Glas, Julia Seiderer, Stephanie Bues, Johannes Stallhofer, Christoph Fries, Torsten Olszak, Eleni Tsekeri, Martin Wetzke, Florian Beigel, Christian Steib, Matthias Friedrich, Burkhard Göke, Julia Diegelmann, Darina Czamara, Stephan Brand

PLoS One. 2013; 8(1): e54338. Published online 2013 Jan 24. doi: 10.1371/journal.pone.0054338

PMCID:: PMC3554777

Abstract Article PDF–205K

Select item 346161413.

Association of IRGM Polymorphisms and Susceptibility to Pulmonary Tuberculosis in Zahedan, Southeast Iran

Gholamreza Bahari, Mohammad Hashemi, Mohsen Taheri, Mohammad Naderi, Ebrahim Eskandari-Nasab, Mahdi Atabaki

ScientificWorldJournal. 2012; 2012: 950801. Published online 2012 Sep 23. doi: 10.1100/2012/950801

PMCID:: PMC3461614

Abstract Article PDF–982K

Select item 302501414.

Polymorphic Allele of Human IRGM1 Is Associated with Susceptibility to Tuberculosis in African Americans

Katherine Y. King, Justin D. Lew, Ngan P. Ha, Jeffery S. Lin, Xin Ma, Edward A. Graviss, Margaret A. Goodell

PLoS One. 2011; 6(1): e16317. Published online 2011 Jan 21. doi: 10.1371/journal.pone.0016317

PMCID:: PMC3025014

Abstract Article PDF–117K

Select item 299647615.

Human IRGM Regulates Autophagy and Its Cell-Autonomous Immunity Functions Through Mitochondria

Sudha B. Singh, Wojciech Ornatowski, Isabelle Vergne, John Naylor, Monica Delgado, Esteban Roberts, Marisa Ponpuak, Sharon Master, Manohar Pilli, Eileen White, Masaaki Komatsu, Vojo Deretic

Nat Cell Biol. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Nat Cell Biol. 2010 Dec; 12(12): 1154–1165. Published online 2010 Nov 21. doi: 10.1038/ncb2119

PMCID:: PMC2996476

Abstract Article PDF–2.0M

Select item 285061616.

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

Natalie J. Prescott, Katherine M. Dominy, Michiaki Kubo, Cathryn M. Lewis, Sheila A. Fisher, Richard Redon, Ni Huang, Barbara E. Stranger, Katarzyna Blaszczyk, Barry Hudspith, Gareth Parkes, Naoya Hosono, Keiko Yamazaki, Clive M. Onnie, Alastair Forbes, Emmanouil T. Dermitzakis, Yusuke Nakamura, John C. Mansfield, Jeremy Sanderson, Matthew E. Hurles, Roland G. Roberts, Christopher G. Mathew

Hum Mol Genet. 2010 May 1; 19(9): 1828–1839. Published online 2010 Jan 27. doi: 10.1093/hmg/ddq041

PMCID:: PMC2850616

Abstract Article PDF–287K

Select item 273577817.

Autophagy Gene Variant IRGM −261T Contributes to Protection from Tuberculosis Caused by Mycobacterium tuberculosis but Not by M. africanum Strains

Christopher D. Intemann, Thorsten Thye, Stefan Niemann, Edmund N. L. Browne, Margaret Amanua Chinbuah, Anthony Enimil, John Gyapong, Ivy Osei, Ellis Owusu-Dabo, Susanne Helm, Sabine Rüsch-Gerdes, Rolf D. Horstmann, Christian G. Meyer

PLoS Pathog. 2009 Sep; 5(9): e1000577. Published online 2009 Sep 11. doi: 10.1371/journal.ppat.1000577

PMCID:: PMC2735778

Abstract Article PDF–434K

Select item 273179918.

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn’s disease

Steven A McCarroll, Alan Huett, Petric Kuballa, Shannon D Chilewski, Aimee Landry, Philippe Goyette, Michael C Zody, Jennifer L Hall, Steven R Brant, Judy H Cho, Richard H Duerr, Mark S Silverberg, Kent D Taylor, John D Rioux, David Altshuler, Mark J Daly, Ramnik J Xavier

Nat Genet. Author manuscript; available in PMC 2009 Aug 25.

Published in final edited form as: Nat Genet. 2008 Sep; 40(9): 1107–1112. doi: 10.1038/ng.215

PMCID:: PMC2731799

Abstract Article PDF–1.5M

Select item 1058245119.

TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM

Mingchuang Sun, Zhaoxing Li, Xiaoyuan Wang, Meirong Zhao, Yuan Chu, Zehua Zhang, Kang Fang, Ziying Zhao, Anqi Feng, Zhuyun Leng, Jianing Shi, Li Zhang, Tao Chen, Meidong Xu

Adv Sci (Weinh) 2023 Oct; 10(29): 2300864. Published online 2023 Sep 13. doi: 10.1002/advs.202300864

PMCID:: PMC10582451

Abstract Article PDF–6.4M

Select item 856723420.

Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses

Parej Nath, Nishant Ranjan Chauhan, Kautilya Kumar Jena, Ankita Datey, Nilima Dinesh Kumar, Subhash Mehto, Saikat De, Tapas Kumar Nayak, Swatismita Priyadarsini, Kshitish Rout, Ramyasingh Bal, Krushna C Murmu, Manjula Kalia, Srinivas Patnaik, Punit Prasad, Fulvio Reggiori, Soma Chattopadhyay, Santosh Chauhan

EMBO Rep. 2021 Nov 4; 22(11): e52948. Published online 2021 Sep 1. doi: 10.15252/embr.202152948

PMCID:: PMC8567234

Abstract Article PDF–2.6M

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