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Select item 61858551.

In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein

Agnes Karasik, András Váradi, Flóra Szeri

PLoS One. 2018; 13(10): e0205657. Published online 2018 Oct 12. doi: 10.1371/journal.pone.0205657

PMCID:: PMC6185855

Abstract Article PDF–1.3M

Select item 61376422.

Boosted coupling of ATP hydrolysis to substrate transport upon cooperative estradiol-17-β-D-glucuronide binding in a Drosophila ATP binding cassette type-C transporter

Agnes Karasik, Kaitlyn Victoria Ledwitch, Tamás Arányi, András Váradi, Arthur Roberts, Flóra Szeri

FASEB J. 2018 Feb; 32(2): 669–680. Published online 2017 Sep 22. doi: 10.1096/fj.201700606R

PMCID:: PMC6137642

Abstract Article

Select item 41760533.

Target Organ Specific Activity of Drosophila MRP (ABCC1) Moderates Developmental Toxicity of Methylmercury

Lisa Prince, Malgorzata Korbas, Philip Davidson, Karin Broberg, Matthew Dearborn Rand

Toxicol Sci. 2014 Aug 1; 140(2): 425–435. Published online 2014 May 25. doi: 10.1093/toxsci/kfu095

PMCID:: PMC4176053

Abstract Article PDF–4.7M

Select item 45888964.

Determining exon connectivity in complex mRNAs by nanopore sequencing

Mohan T. Bolisetty, Gopinath Rajadinakaran, Brenton R. Graveley

Genome Biol. 2015; 16: 204. Published online 2015 Sep 30. doi: 10.1186/s13059-015-0777-z

PMCID:: PMC4588896

Abstract Article PDF–1.0M

Select item 82299095.

Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila

Wen Liu, Hao Cao, Moses Kimari, Georgios Maronitis, Michael J. Williams, Helgi B Schiöth

Membranes (Basel) 2021 Jun; 11(6): 432. Published online 2021 Jun 8. doi: 10.3390/membranes11060432

PMCID:: PMC8229909

Abstract Article PDF–1.5M

Select item 76579926.

Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development.

Jakob Gunderson, Ashley Peppriell, Daria Vorojeikina, Matthew D. Rand

Arch Toxicol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Arch Toxicol. 2020 Dec; 94(12): 4007–4022. Published online 2020 Aug 20. doi: 10.1007/s00204-020-02879-z

PMCID:: PMC7657992

Abstract Article PDF–4.0M

Select item 48503597.

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis

Jorge Iván Castillo-Quan, Li Li, Kerri J. Kinghorn, Dobril K. Ivanov, Luke S. Tain, Cathy Slack, Fiona Kerr, Tobias Nespital, Janet Thornton, John Hardy, Ivana Bjedov, Linda Partridge

Cell Rep. 2016 Apr 19; 15(3): 638–650. Published online 2016 Apr 7. doi: 10.1016/j.celrep.2016.03.041

PMCID:: PMC4850359

Abstract Article

Select item 57752898.

Notch Target Gene E(spl)mδ Is a Mediator of Methylmercury-Induced Myotoxicity in Drosophila

Lisa M. Prince, Matthew D. Rand

Front Genet. 2017; 8: 233. Published online 2018 Jan 15. doi: 10.3389/fgene.2017.00233

PMCID:: PMC5775289

Abstract Article PDF–2.3M

Select item 41749429.

Using Drosophila melanogaster To Identify Chemotherapy Toxicity Genes

Elizabeth G. King, Galina Kislukhin, Kelli N. Walters, Anthony D. Long

Genetics. 2014 Sep; 198(1): 31–43. Published online 2014 Sep 1. doi: 10.1534/genetics.114.161968

PMCID:: PMC4174942

Abstract Article PDF–2.0M

Select item 387774310.

Integrating protein-protein interaction networks with phenotypes reveals signs of interactions

Arunachalam Vinayagam, Jonathan Zirin, Charles Roesel, Yanhui Hu, Bahar Yilmazel, Anastasia A. Samsonova, Ralph A. Neumüller, Stephanie E. Mohr, Norbert Perrimon

Nat Methods. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Nat Methods. 2014 Jan; 11(1): 94–99. Published online 2013 Nov 17. doi: 10.1038/nmeth.2733

PMCID:: PMC3877743

Abstract Article PDF–1.6M

Select item 1046830311.

Using Drosophila to identify naturally occurring genetic modifiers of amyloid beta 42- and tau-induced toxicity

Ming Yang, Matthew Zinkgraf, Cecilia Fitzgerald-Cook, Benjamin R Harrison, Alexandra Putzier, Daniel E L Promislow, Adrienne M Wang

G3 (Bethesda) 2023 Sep; 13(9): jkad132. Published online 2023 Jun 13. doi: 10.1093/g3journal/jkad132

PMCID:: PMC10468303

Abstract Article PDF–8.0M

Select item 660684812.

Rare variants in MYH15 modify amyotrophic lateral sclerosis risk

Hyerim Kim, Junghwa Lim, Han Bao, Bin Jiao, Se Min Canon, Michael P Epstein, Keqin Xu, Jie Jiang, Janani Parameswaran, Yingjie Li, Kenneth H Moberg, John E Landers, Christina Fournier, Emily G Allen, Jonathan D Glass, Thomas S Wingo, Peng Jin

Hum Mol Genet. 2019 Jul 15; 28(14): 2309–2318. Published online 2019 Apr 1. doi: 10.1093/hmg/ddz063

PMCID:: PMC6606848

Abstract Article PDF–27M

Select item 304057713.

Evolutionary Conservation of Vertebrate Blood–Brain Barrier Chemoprotective Mechanisms in Drosophila

Fahima Mayer, Nasima Mayer, Leslie Chinn, Robert L. Pinsonneault, Deanna Kroetz, Roland J. Bainton

J Neurosci. 2009 Mar 18; 29(11): 3538–3550. doi: 10.1523/JNEUROSCI.5564-08.2009

PMCID:: PMC3040577

Abstract Article PDF–661K

Select item 666909014.

The Drosophila Malpighian Tubule as a Model for Mammalian Tubule Function

Aylin R. Rodan

Curr Opin Nephrol Hypertens. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Curr Opin Nephrol Hypertens. 2019 Sep; 28(5): 455–464. doi: 10.1097/MNH.0000000000000521

PMCID:: PMC6669090

Abstract Article PDF–794K

Select item 587390715.

The Molecular and Genetic Characterization of Second Chromosome Balancers in Drosophila melanogaster

Danny E. Miller, Kevin R. Cook, Elizabeth A. Hemenway, Vivienne Fang, Angela L. Miller, Karen G. Hales, R. Scott Hawley

G3 (Bethesda) 2018 Apr; 8(4): 1161–1171. Published online 2018 Feb 2. doi: 10.1534/g3.118.200021

PMCID:: PMC5873907

Abstract Article PDF–1.8M

Select item 916152316.

Identification and characterization of a heme exporter from the MRP family in Drosophila melanogaster

Zhiqing Wang, Peng Zeng, Bing Zhou

BMC Biol. 2022; 20: 126. Published online 2022 Jun 2. doi: 10.1186/s12915-022-01332-0

PMCID:: PMC9161523

Abstract Article PDF–10M

Select item 911494417.

Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster

Shane Denecke, Hằng Ngọc Bảo Lương, Venetia Koidou, Maria Kalogeridi, Rafaella Socratous, Steven Howe, Kathrin Vogelsang, Ralf Nauen, Philip Batterham, Sven Geibel, John Vontas

Proc Biol Sci. May 25, 2022; 289(1975): 20220625. Published online May 18, 2022. doi: 10.1098/rspb.2022.0625

PMCID:: PMC9114944

Abstract Article PDF–975K

Select item 15599118.

Genome-wide analysis of nuclear mRNA export pathways in Drosophila

Andrea Herold, Luis Teixeira, Elisa Izaurralde

EMBO J. 2003 May 15; 22(10): 2472–2483. doi: 10.1093/emboj/cdg233

PMCID:: PMC155991

Abstract Article PDF–614K

Select item 911803519.

A genetic screen in Drosophila reveals the role of fucosylation in host susceptibility to Candida infection

Marcus T. Glittenberg, Ilias Kounatidis, Magda Atilano, Petros Ligoxygakis

Dis Model Mech. 2022 May 1; 15(5): dmm049218. Published online 2022 May 9. doi: 10.1242/dmm.049218

PMCID:: PMC9118035

Abstract Article

Select item 539197020.

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases

Rachel A. Kline, Kevin A. Kaifer, Erkan Y. Osman, Francesco Carella, Ariana Tiberi, Jolill Ross, Giuseppa Pennetta, Christian L. Lorson, Lyndsay M. Murray

PLoS Genet. 2017 Mar; 13(3): e1006680. Published online 2017 Mar 31. doi: 10.1371/journal.pgen.1006680