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Items: 1 to 20 of 44

1.
Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila
Ashutosh Pandey, Antonio Galeone, Seung Yeop Han, Benjamin A. Story, Gaia Consonni, William F. Mueller, Lars M. Steinmetz, Thomas Vaccari, Hamed Jafar-Nejad
Nat Commun. 2023; 14: 5667. Published online 2023 Sep 13. doi: 10.1038/s41467-023-40910-w
PMCID:
PMC10499810
AbstractArticlePDF–7.5M
2.
Defects in the Neuroendocrine Axis Contribute to Global Development Delay in a Drosophila Model of NGLY1 Deficiency
Tamy Portillo Rodriguez, Joshua D. Mast, Tom Hartl, Tom Lee, Peter Sand, Ethan O. Perlstein
G3 (Bethesda) 2018 Jul; 8(7): 2193–2204. Published online 2018 May 7. doi: 10.1534/g3.118.300578
Correction in:
G3 (Bethesda). 2019 Jan; 9(1): 315.
PMCID:
PMC6027897
AbstractArticlePDF–2.3M
3.
Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches
Katie G Owings, Joshua B Lowry, Yiling Bi, Matthew Might, Clement Y Chow
Hum Mol Genet. 2018 Mar 15; 27(6): 1055–1066. Published online 2018 Jan 15. doi: 10.1093/hmg/ddy026
PMCID:
PMC5886220
AbstractArticlePDF–532K
4.
An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency
Kevin A. Hope, Alexys R. Berman, Randall T. Peterson, Clement Y. Chow
PLoS Genet. 2022 Jun; 18(6): e1010228. Published online 2022 Jun 2. doi: 10.1371/journal.pgen.1010228
PMCID:
PMC9162339
AbstractArticlePDF–2.6M
5.
Evidence for an Essential Deglycosylation-Independent Activity of PNGase in Drosophila melanogaster
Yoko Funakoshi, Yuki Negishi, J. Peter Gergen, Junichi Seino, Kumiko Ishii, William J. Lennarz, Ichiro Matsuo, Yukishige Ito, Naoyuki Taniguchi, Tadashi Suzuki
PLoS One. 2010; 5(5): e10545. Published online 2010 May 10. doi: 10.1371/journal.pone.0010545
PMCID:
PMC2866665
AbstractArticlePDF–2.0M
6.
Tracing the NGLY1 footprints: insights from Drosophila
Ashutosh Pandey, Hamed Jafar-Nejad
J Biochem. 2022 Feb; 171(2): 153–160. Published online 2021 Jul 16. doi: 10.1093/jb/mvab084
PMCID:
PMC9005052
AbstractArticlePDF–743K
7.
A conserved role for AMP-activated protein kinase in NGLY1 deficiency
Seung Yeop Han, Ashutosh Pandey, Tereza Moore, Antonio Galeone, Lita Duraine, Tina M. Cowan, Hamed Jafar-Nejad
PLoS Genet. 2020 Dec; 16(12): e1009258. Published online 2020 Dec 14. doi: 10.1371/journal.pgen.1009258
PMCID:
PMC7769621
AbstractArticlePDF–3.7M
8.
A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency
Dana M Talsness, Katie G Owings, Emily Coelho, Gaelle Mercenne, John M Pleinis, Raghavendran Partha, Kevin A Hope, Aamir R Zuberi, Nathan L Clark, Cathleen M Lutz, Aylin R Rodan, Clement Y Chow
eLife. 2020; 9: e57831. Published online 2020 Dec 14. doi: 10.7554/eLife.57831
PMCID:
PMC7758059
AbstractArticlePDF–1.1M
9.
Cytosolic O-GlcNAcylation and PNG1 maintain Drosophila gut homeostasis by regulating proliferation and apoptosis
Hyun-jin Na, Lara K. Abramowitz, John A. Hanover
PLoS Genet. 2022 Mar; 18(3): e1010128. Published online 2022 Mar 16. doi: 10.1371/journal.pgen.1010128
PMCID:
PMC8959174
AbstractArticlePDF–5.7M
10.
Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation
Antonio Galeone, Joshua M Adams, Shinya Matsuda, Maximiliano F Presa, Ashutosh Pandey, Seung Yeop Han, Yuriko Tachida, Hiroto Hirayama, Thomas Vaccari, Tadashi Suzuki, Cathleen M Lutz, Markus Affolter, Aamir Zuberi, Hamed Jafar-Nejad
eLife. 2020; 9: e55596. Published online 2020 Jul 28. doi: 10.7554/eLife.55596
PMCID:
PMC7394544
AbstractArticlePDF–9.4M
11.
Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1
Antonio Galeone, Seung Yeop Han, Chengcheng Huang, Akira Hosomi, Tadashi Suzuki, Hamed Jafar-Nejad
eLife. 2017; 6: e27612. Published online 2017 Aug 4. doi: 10.7554/eLife.27612
PMCID:
PMC5599231
AbstractArticlePDF–9.5M
12.
highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models
Huai-Wei Huang, Brian Brown, Jaehoon Chung, Pedro M. Domingos, Hyung Don Ryoo
Cell Rep. Author manuscript; available in PMC 2018 Mar 1.
Published in final edited form as: Cell Rep. 2018 Feb 6; 22(6): 1384–1391. doi: 10.1016/j.celrep.2018.01.032
PMCID:
PMC5832065
AbstractArticlePDF–1.4M
13.
A Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin
Jinguo Cao, Yi Li, Wenjing Xia, Keith Reddig, Wen Hu, Wei Xie, Hong-Sheng Li, Junhai Han
EMBO J. 2011 Sep 14; 30(18): 3701–3713. Published online 2011 Jul 29. doi: 10.1038/emboj.2011.254
PMCID:
PMC3173788
AbstractArticlePDF–1.4M
14.
Activation of Sterol Regulatory Element Binding Proteins in the Absence of Scap in Drosophila melanogaster
Krista A. Matthews, Cafer Ozdemir, Robert B. Rawson
Genetics. 2010 May; 185(1): 189–198. doi: 10.1534/genetics.110.114975
PMCID:
PMC2870954
AbstractArticlePDF–1.8M
15.
The N’s and O’s of Drosophila Glycoprotein Glycobiology
Toshihiko Katoh, Michael Tiemeyer
Glycoconj J. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Glycoconj J. 2013 Jan; 30(1): 57–66. Published online 2012 Aug 31. doi: 10.1007/s10719-012-9442-x
PMCID:
PMC3548036
AbstractArticlePDF–1.0M
16.
PHYSIOLOGIC AND ANATOMIC CHARACTERIZATION OF THE BRAIN SURFACE GLIA BARRIER OF DROSOPHILA
Michael K. DeSalvo, Nasima Mayer, Fahima Mayer, Roland J. Bainton
Glia. Author manuscript; available in PMC 2012 Sep 1.
Published in final edited form as: Glia. 2011 Sep; 59(9): 1322–1340. Published online 2011 Feb 23. doi: 10.1002/glia.21147
PMCID:
PMC3130812
AbstractArticlePDF–4.6M
17.
The transcription factor Cabut coordinates energy metabolism and the circadian clock in response to sugar sensing
Osnat Bartok, Mari Teesalu, Reut Ashwall-Fluss, Varun Pandey, Mor Hanan, Bohdana M Rovenko, Minna Poukkula, Essi Havula, Arieh Moussaieff, Sadanand Vodala, Yaakov Nahmias, Sebastian Kadener, Ville Hietakangas
EMBO J. 2015 Jun 3; 34(11): 1538–1553. Published online 2015 Apr 27. doi: 10.15252/embj.201591385
PMCID:
PMC4474529
AbstractArticlePDF–1.7M
18.
Genetic Annotation of Gain-Of-Function Screens Using RNA Interference and in Situ Hybridization of Candidate Genes in the Drosophila Wing
Cristina Molnar, Mar Casado, Ana López-Varea, Cristina Cruz, Jose F. de Celis
Genetics. 2012 Oct; 192(2): 741–752. doi: 10.1534/genetics.112.143537
PMCID:
PMC3454894
AbstractArticlePDF–2.6M
19.
A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins
Annabel Guichard, Shenzhao Lu, Oguz Kanca, Daniel Bressan, Yan Huang, Mengqi Ma, Sara Sanz Juste, Jonathan C. Andrews, Kristy L. Jay, Marketta Sneider, Ruth Schwartz, Mei-Chu Huang, Danqing Bei, Hongling Pan, Liwen Ma, Wen-Wen Lin, Ankush Auradkar, Pranjali Bhagwat, Soo Park, Kenneth H. Wan, Takashi Ohsako, Toshiyuki Takano-Shimizu, Susan E. Celniker, Michael F. Wangler, Shinya Yamamoto, Hugo J. Bellen, Ethan Bier
Cell Rep. Author manuscript; available in PMC 2024 Mar 25.
Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112842. Published online 2023 Jul 20. doi: 10.1016/j.celrep.2023.112842
PMCID:
PMC10962759
AbstractArticlePDF–3.0M
20.
A Gain-of-Function Screen Identifying Genes Required for Vein Formation in the Drosophila melanogaster Wing
Cristina Molnar, Ana López-Varea, Rosario Hernández, Jose F. de Celis
Genetics. 2006 Nov; 174(3): 1635–1659. doi: 10.1534/genetics.106.061283
PMCID:
PMC1667087
AbstractArticlePDF–1.8M

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