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Items: 1 to 20 of 117

1.
Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7
Yang Yue, T. Lynne Blasius, Stephanie Zhang, Shashank Jariwala, Benjamin Walker, Barry J. Grant, Jared C. Cochran, Kristen J. Verhey
J Cell Biol. 2018 Apr 2; 217(4): 1319–1334. doi: 10.1083/jcb.201708179
PMCID:
PMC5881503
AbstractArticlePDF–2.5M
2.
An Intramolecular Association between Two Domains of the Protein Kinase Fused Is Necessary for Hedgehog Signaling
Manuel Ascano, Jr., David J. Robbins
Mol Cell Biol. 2004 Dec; 24(23): 10397–10405. doi: 10.1128/MCB.24.23.10397-10405.2004
PMCID:
PMC529051
AbstractArticlePDF–577K
3.
The Carboxyl-Terminal Domain of the Protein Kinase Fused Can Function as a Dominant Inhibitor of Hedgehog Signaling
Manuel Ascano, Jr., Kent E. Nybakken, Janek Sosinski, Melanie A. Stegman, David J. Robbins
Mol Cell Biol. 2002 Mar; 22(5): 1555–1566. doi: 10.1128/mcb.22.5.1555-1566.2002
PMCID:
PMC134684
AbstractArticlePDF–886K
4.
Contributions of Costal 2-Fused interactions to Hedgehog signaling in Drosophila
Eva V. Zadorozny, Jamie C. Little, Daniel Kalderon
Development. 2015 Mar 1; 142(5): 931–942. doi: 10.1242/dev.112904
PMCID:
PMC4352975
AbstractArticle
5.
Functional Domains of Fused, a Serine-Threonine Kinase Required for Signaling in Drosophila
P. Therond, G. Alves, B. Limbourg-Bouchon, H. Tricoire, E. Guillemet, J. Brissard-Zahraoui, C. Lamour-Isnard, D. Busson
Genetics. 1996 Apr; 142(4): 1181–1198. doi: 10.1093/genetics/142.4.1181
PMCID:
PMC1207117
SummaryPDF–3.7M
6.
Segmental Polarity in Drosophila Melanogaster: Genetic Dissection of Fused in a Suppressor of Fused Background Reveals Interaction with Costal-2
T. Preat, P. Therond, B. Limbourg-Bouchon, A. Pham, H. Tricoire, D. Busson, C. Lamour-Isnard
Genetics. 1993 Dec; 135(4): 1047–1062. doi: 10.1093/genetics/135.4.1047
PMCID:
PMC1205737
SummaryPDF–9.0M
7.
The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells
Giorgia Giordani, Marilena Barraco, Angela Giangrande, Giovanni Martinelli, Viviana Guadagnuolo, Giorgia Simonetti, Giovanni Perini, Roberto Bernardoni
Oncotarget. 2016 Aug 23; 7(34): 55313–55327. Published online 2016 Jul 28. doi: 10.18632/oncotarget.10879
PMCID:
PMC5342419
AbstractArticlePDF–8.7M
8.
The Suppressor of Fused Gene Encodes a Novel Pest Protein Involved in Drosophila Segment Polarity Establishment
A. Pham, P. Therond, G. Alves, F. B. Tournier, D. Busson, C. Lamour-Isnard, B. L. Bouchon, T. Preat, H. Tricoire
Genetics. 1995 Jun; 140(2): 587–598. doi: 10.1093/genetics/140.2.587
PMCID:
PMC1206637
SummaryPDF–6.5M
9.
The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development.
J Capdevila, M P Estrada, E Sánchez-Herrero, I Guerrero
EMBO J. 1994 Jan 1; 13(1): 71–82. doi: 10.1002/j.1460-2075.1994.tb06236.x
PMCID:
PMC394780
SummaryPage BrowsePDF–4.3M
10.
Patched and Costal-2 mutations lead to differences in tissue overgrowth autonomy
Shannon L. Moore, Frank C. Adamini, Erik S. Coopes, Dustin Godoy, Shyra J. Northington, Jordan M. Stewart, Richard L Tillett, Kayla L. Bieser, Jacob D. Kagey
Fly (Austin) 2022; 16(1): 176–189. Published online 2022 Apr 25. doi: 10.1080/19336934.2022.2062991
PMCID:
PMC9045829
AbstractArticlePDF–12M
11.
Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner
Junkai Fan, Yajuan Liu, Jianhang Jia
Dev Biol. Author manuscript; available in PMC 2013 Jun 15.
Published in final edited form as: Dev Biol. 2012 Jun 15; 366(2): 172–184. Published online 2012 Apr 19. doi: 10.1016/j.ydbio.2012.04.007
PMCID:
PMC3572470
AbstractArticlePDF–2.7M
12.
The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation
Candace E. Carroll, Suresh Marada, Daniel P. Stewart, J. Xiaoxi Ouyang, Stacey K. Ogden
Development. 2012 Feb 1; 139(3): 612–621. doi: 10.1242/dev.075614
Correction in:
Development. 2012 Feb 15; 139(4): 827.
PMCID:
PMC3252357
AbstractArticle
13.
A Quantification of Pathway Components Supports a Novel Model of Hedgehog Signal Transduction
Shohreh F. Farzan, Melanie A. Stegman, Stacey K. Ogden, Manuel Ascano, Jr, Kendall E. Black, Ofelia Tacchelly, David J. Robbins
J Biol Chem. 2009 Oct 16; 284(42): 28874–28884. Published online 2009 Aug 28. doi: 10.1074/jbc.M109.041608
PMCID:
PMC2781433
AbstractArticlePDF–1.9M
14.
Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation
Shuang Li, Guoqiang Ma, Bing Wang, Jin Jiang
Sci Signal. Author manuscript; available in PMC 2015 Oct 27.
Published in final edited form as: Sci Signal. 2014 Jul 1; 7(332): ra62. Published online 2014 Jul 1. doi: 10.1126/scisignal.2005414
PMCID:
PMC4621970
AbstractArticlePDF–2.4M
15.
A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response
Sekyung Oh, Masaki Kato, Chi Zhang, Yurong Guo, Philip A. Beachy
PLoS One. 2015; 10(8): e0135804. Published online 2015 Aug 13. doi: 10.1371/journal.pone.0135804
PMCID:
PMC4536226
AbstractArticlePDF–8.1M
16.
A Broadly Conserved G-Protein-Coupled Receptor Kinase Phosphorylation Mechanism Controls Drosophila Smoothened Activity
Dominic Maier, Shuofei Cheng, Denis Faubert, David R. Hipfner
PLoS Genet. 2014 Jul; 10(7): e1004399. Published online 2014 Jul 10. doi: 10.1371/journal.pgen.1004399
PMCID:
PMC4091690
AbstractArticlePDF–1.6M
17.
Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2
Stacey K. Ogden, Manuel Ascano, Jr., Melanie A. Stegman, Liza M. Suber, Joan E. Hooper, David J. Robbins
Curr Biol. Author manuscript; available in PMC 2013 Jul 15.
Published in final edited form as: Curr Biol. 2003 Nov 11; 13(22): 1998–2003. doi: 10.1016/j.cub.2003.10.004
PMCID:
PMC3711143
AbstractArticlePDF–1.0M
18.
The Kinesin-related Protein Costal2 Associates with Membranes in a Hedgehog-sensitive, Smoothened-independent Manner
Melanie A. Stegman, John A. Goetz, Manuel Ascano, Jr., Stacey K. Ogden, Kent E. Nybakken, David J. Robbins
J Biol Chem. Author manuscript; available in PMC 2013 May 21.
Published in final edited form as: J Biol Chem. 2004 Feb 20; 279(8): 7064–7071. Published online 2003 Nov 28. doi: 10.1074/jbc.M311794200
PMCID:
PMC3659396
AbstractArticlePDF–1.8M
19.
Costal 2 interactions with Cubitus interruptus (Ci) underlying Hedgehog-regulated Ci processing
Qianhe Zhou, Daniel Kalderon
Dev Biol. Author manuscript; available in PMC 2011 Dec 1.
Published in final edited form as: Dev Biol. 2010 Dec 1; 348(1): 47–57. Published online 2010 Sep 17. doi: 10.1016/j.ydbio.2010.09.004
PMCID:
PMC2996228
AbstractArticlePDF–2.3M
20.
Fused–Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation
Yajuan Liu, Xuesong Cao, Jin Jiang, Jianhang Jia
Genes Dev. 2007 Aug 1; 21(15): 1949–1963. doi: 10.1101/gad.1557407
PMCID:
PMC1935032
AbstractArticlePDF–1.4M

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