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Select item 43679681.

An automated image analysis method to measure regularity in biological patterns: a case study in a Drosophila neurodegenerative model

Sergio Diez-Hermano, Jorge Valero, Cristina Rueda, Maria D Ganfornina, Diego Sanchez

Mol Neurodegener. 2015; 10: 9. Published online 2015 Mar 12. doi: 10.1186/s13024-015-0005-z

PMCID:: PMC4367968

Abstract Article PDF–3.7M

Select item 71085862.

Altered lipid metabolism in a Drosophila model of Friedreich's ataxia

Juan A. Navarro, Elisabeth Ohmann, Diego Sanchez, José A. Botella, Gerhard Liebisch, María D. Moltó, María D. Ganfornina, Gerd Schmitz, Stephan Schneuwly

Hum Mol Genet. 2010 Jul 15; 19(14): 2828–2840. Published online 2010 May 10. doi: 10.1093/hmg/ddq183

PMCID:: PMC7108586

Abstract Article PDF–718K

Select item 53255893.

Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress

Raquel Pascua-Maestro, Sergio Diez-Hermano, Concepción Lillo, Maria D. Ganfornina, Diego Sanchez

PLoS Genet. 2017 Feb; 13(2): e1006603. Published online 2017 Feb 9. doi: 10.1371/journal.pgen.1006603

PMCID:: PMC5325589

Abstract Article PDF–3.9M

Select item 23745524.

Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila

Julien Muffat, David W. Walker, Seymour Benzer

Proc Natl Acad Sci U S A. 2008 May 13; 105(19): 7088–7093. Published online 2008 May 5. doi: 10.1073/pnas.0800896105

PMCID:: PMC2374552

Abstract Article PDF–745K

Select item 102159705.

Apolipoprotein D in Oxidative Stress and Inflammation

Guillaume Fyfe-Desmarais, Fréderik Desmarais, Éric Rassart, Catherine Mounier

Antioxidants (Basel) 2023 May; 12(5): 1027. Published online 2023 Apr 28. doi: 10.3390/antiox12051027

PMCID:: PMC10215970

Abstract Article PDF–1.3M

Select item 43742956.

Manuela del Caño-Espinel, Judith R Acebes, Diego Sanchez, Maria D Ganfornina

Mol Neurodegener. 2015; 10: 11. Published online 2015 Mar 19. doi: 10.1186/s13024-015-0009-8

PMCID:: PMC4374295

Abstract Article PDF–2.0M

Select item 102090777.

Glycolytically impaired Drosophila glial cells fuel neural metabolism via β-oxidation

Ellen McMullen, Helen Hertenstein, Katrin Strassburger, Leon Deharde, Marko Brankatschk, Stefanie Schirmeier

Nat Commun. 2023; 14: 2996. Published online 2023 May 24. doi: 10.1038/s41467-023-38813-x

PMCID:: PMC10209077

Abstract Article PDF–1.1M

Select item 92788648.

Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia

Liping Wang, Guang Lin, Zhongyuan Zuo, Yarong Li, Seul Kee Byeon, Akhilesh Pandey, Hugo J. Bellen

Sci Adv. 2022 Jul; 8(28): eabn3326. Published online 2022 Jul 13. doi: 10.1126/sciadv.abn3326

PMCID:: PMC9278864

Abstract Article PDF–9.4M

Select item 68261359.

The role of lipid metabolism in aging, lifespan regulation, and age‐related disease

Adiv A. Johnson, Alexandra Stolzing

Aging Cell. 2019 Dec; 18(6): e13048. Published online 2019 Sep 27. doi: 10.1111/acel.13048

PMCID:: PMC6826135

Abstract Article PDF–1.2M

Select item 232378410.

Genetic Dissociation of Ethanol Sensitivity and Memory Formation in Drosophila melanogaster

Holly LaFerriere, Douglas J. Guarnieri, Divya Sitaraman, Soeren Diegelmann, Ulrike Heberlein, Troy Zars

Genetics. 2008 Apr; 178(4): 1895–1902. doi: 10.1534/genetics.107.084582

PMCID:: PMC2323784

Abstract Article PDF–370K

Select item 937836111.

‘Fly’ing from rare to common neurodegenerative disease mechanisms

Mengqi Ma, Matthew J. Moulton, Shenzhao Lu, Hugo J. Bellen

Trends Genet. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Trends Genet. 2022 Sep; 38(9): 972–984. Published online 2022 Apr 25. doi: 10.1016/j.tig.2022.03.018

PMCID:: PMC9378361

Abstract Article PDF–1.0M

Select item 1100158612.

A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis

Paula R. Haynes, Elana S. Pyfrom, Yongjun Li, Carly Stein, Vishnu Anand Cuddapah, Jack A. Jacobs, Zhifeng Yue, Amita Sehgal

Nat Neurosci. 2024; 27(4): 666–678. Published online 2024 Feb 15. doi: 10.1038/s41593-023-01568-1

PMCID:: PMC11001586

Abstract Article PDF–5.6M

Select item 362688313.

Of flies and men: insights on organismal metabolism from fruit flies

Akhila Rajan, Norbert Perrimon

BMC Biol. 2013; 11: 38. Published online 2013 Apr 15. doi: 10.1186/1741-7007-11-38

PMCID:: PMC3626883

Abstract Article PDF–621K

Select item 871988514.

Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer’s disease–associated genes

Matthew J. Moulton, Scott Barish, Isha Ralhan, Jinlan Chang, Lindsey D. Goodman, Jake G. Harland, Paul C. Marcogliese, Jan O. Johansson, Maria S. Ioannou, Hugo J. Bellen

Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2112095118. Published online 2021 Dec 23. doi: 10.1073/pnas.2112095118

PMCID:: PMC8719885

Abstract Article PDF–2.8M

Select item 806514415.

Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling

Jun Yin, Emma Spillman, Ethan S. Cheng, Jacob Short, Yang Chen, Jingce Lei, Mary Gibbs, Justin S. Rosenthal, Chengyu Sheng, Yuki X. Chen, Kelly Veerasammy, Tenzin Choetso, Rinat Abzalimov, Bei Wang, Chun Han, Ye He, Quan Yuan

Nat Commun. 2021; 12: 2408. Published online 2021 Apr 23. doi: 10.1038/s41467-021-22751-7