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Select item 14604311.

skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter release.

B A Hassan, S N Prokopenko, S Breuer, B Zhang, A Paululat, H J Bellen

Genetics. 1998 Dec; 150(4): 1527–1537. doi: 10.1093/genetics/150.4.1527

PMCID:: PMC1460431

Summary PDF–362K

Select item 66058112.

PTEN reduces endosomal PtdIns(4,5)P₂ in a phosphatase-independent manner via a PLC pathway

Virginie E. Mondin, Khaled Ben El Kadhi, Clothilde Cauvin, Anthony Jackson-Crawford, Emilie Bélanger, Barbara Decelle, Rémi Salomon, Martin Lowe, Arnaud Echard, Sébastien Carréno

J Cell Biol. 2019 Jul 1; 218(7): 2198–2214. Published online 2019 May 22. doi: 10.1083/jcb.201805155

PMCID:: PMC6605811

Abstract Article PDF–4.3M

Select item 46830983.

An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis

Giorgia Guglielmi, Joseph D. Barry, Wolfgang Huber, Stefano De Renzis

Dev Cell. 2015 Dec 7; 35(5): 646–660. doi: 10.1016/j.devcel.2015.10.020

PMCID:: PMC4683098

Abstract Article

Select item 89218344.

Septins tune lipid kinase activity and PI(4,5)P₂ turnover during G-protein–coupled PLC signalling in vivo

Aastha Kumari, Avishek Ghosh, Sourav Kolay, Padinjat Raghu

Life Sci Alliance. 2022 Jun; 5(6): e202101293. Published online 2022 Mar 11. doi: 10.26508/lsa.202101293

PMCID:: PMC8921834

Abstract Article PDF–2.1M

Select item 31877145.

Molecular networks linked by Moesin drive remodeling of the cell cortex during mitosis

Chantal Roubinet, Barbara Decelle, Gaëtan Chicanne, Jonas F. Dorn, Bernard Payrastre, François Payre, Sébastien Carreno

J Cell Biol. 2011 Oct 3; 195(1): 99–112. doi: 10.1083/jcb.201106048

PMCID:: PMC3187714

Abstract Article PDF–3.3M

Select item 25169286.

Overexpression of Partner of Numb Induces Asymmetric Distribution of the PI4P 5-Kinase Skittles in Mitotic Sensory Organ Precursor Cells in Drosophila

Carolina N. L. R. Perdigoto, Louis Gervais, Erin Overstreet, Janice Fischer, Antoine Guichet, François Schweisguth

PLoS One. 2008; 3(8): e3072. Published online 2008 Aug 27. doi: 10.1371/journal.pone.0003072

PMCID:: PMC2516928

Abstract Article PDF–1.4M

Select item 76113437.

A PI4KIIIα protein complex is required for cell viability during Drosophila wing development

Urbashi Basu, Sruthi S Balakrishnan, Vishnu Janardan, Padinjat Raghu

Dev Biol. Author manuscript; available in PMC 2021 Jul 21.

Published in final edited form as: Dev Biol. 2020 Jun 15; 462(2): 208–222. Published online 2020 Mar 17. doi: 10.1016/j.ydbio.2020.03.008

PMCID:: PMC7611343

Abstract Article PDF–2.6M

Select item 14709658.

The direct interaction between ASH2, a Drosophila trithorax group protein, and SKTL, a nuclear phosphatidylinositol 4-phosphate 5-kinase, implies a role for phosphatidylinositol 4,5-bisphosphate in maintaining transcriptionally active chromatin.

Mimi K Cheng, Allen Shearn

Genetics. 2004 Jul; 167(3): 1213–1223. doi: 10.1534/genetics.103.018721

PMCID:: PMC1470965

Summary PDF–564K

Select item 90160039.

PI(4,5)P2 controls slit diaphragm formation and endocytosis in Drosophila nephrocytes

Maximilian M. Gass, Sarah Borkowsky, Marie-Luise Lotz, Rebecca Siwek, Rita Schröter, Pavel Nedvetsky, Stefan Luschnig, Astrid Rohlmann, Markus Missler, Michael P. Krahn

Cell Mol Life Sci. 2022 May; 79(5): 248. Published online 2022 Apr 18. doi: 10.1007/s00018-022-04273-7

PMCID:: PMC9016003

Abstract Article PDF–7.2M

Select item 684200110.

Interplay between integrins and PI4P5K Sktl is crucial for cell polarization and reepithelialisation during Drosophila wound healing

Si-Hyoung Park, Chan-wool Lee, Kwang-Min Choe

Sci Rep. 2019; 9: 16331. Published online 2019 Nov 8. doi: 10.1038/s41598-019-52743-z

PMCID:: PMC6842001

Abstract Article PDF–2.4M

Select item 431071711.

A dPIP5K Dependent Pool of Phosphatidylinositol 4,5 Bisphosphate (PIP₂) Is Required for G-Protein Coupled Signal Transduction in Drosophila Photoreceptors

Purbani Chakrabarti, Sourav Kolay, Shweta Yadav, Kamalesh Kumari, Amit Nair, Deepti Trivedi, Padinjat Raghu

PLoS Genet. 2015 Jan; 11(1): e1004948. Published online 2015 Jan 29. doi: 10.1371/journal.pgen.1004948

PMCID:: PMC4310717

Abstract Article PDF–1.4M

Select item 404057312.

Polarized deposition of basement membrane proteins depends on Phosphatidylinositol synthase and the levels of Phosphatidylinositol 4,5-bisphosphate

Olivier Devergne, Karen Tsung, Gail Barcelo, Trudi Schüpbach

Proc Natl Acad Sci U S A. 2014 May 27; 111(21): 7689–7694. Published online 2014 May 14. doi: 10.1073/pnas.1407351111

PMCID:: PMC4040573

Abstract Article PDF–1.4M

Select item 320320913.

Depletion of plasma membrane PtdIns(4,5)P₂ reveals essential roles for phosphoinositides in flagellar biogenesis

Ho-Chun Wei, Janet Rollins, Lacramioara Fabian, Madeline Hayes, Gordon Polevoy, Christopher Bazinet, Julie A. Brill

J Cell Sci. Author manuscript; available in PMC 2011 Oct 28.

Published in final edited form as: J Cell Sci. 2008 Apr 1; 121(Pt 7): 1076–1084. Published online 2008 Mar 11. doi: 10.1242/jcs.024927

PMCID:: PMC3203209

Abstract Article PDF–1.8M

Select item 802340414.

Hedgehog signaling and Tre1 regulate actin dynamics through PI(4,5)P₂ to direct migration of Drosophila embryonic germ cells

Ji Hoon Kim, Caitlin D. Hanlon, Sunaina Vohra, Peter N. Devreotes, Deborah J. Andrew

Cell Rep. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Cell Rep. 2021 Mar 2; 34(9): 108799. doi: 10.1016/j.celrep.2021.108799

PMCID:: PMC8023404

Abstract Article PDF–3.2M

Select item 635821715.

Dynein-mediated transport and membrane trafficking control PAR3 polarised distribution

Julie Jouette, Antoine Guichet, Sandra B Claret

eLife. 2019; 8: e40212. Published online 2019 Jan 23. doi: 10.7554/eLife.40212

PMCID:: PMC6358217

Abstract Article PDF–6.4M

Select item 286161316.

Phosphatidylinositol 4,5-bisphosphate Directs Spermatid Cell Polarity and Exocyst Localization in Drosophila

Lacramioara Fabian, Ho-Chun Wei, Janet Rollins, Tatsuhiko Noguchi, J. Todd Blankenship, Kishan Bellamkonda, Gordon Polevoy, Louis Gervais, Antoine Guichet, Margaret T. Fuller, Julie A. Brill

Mol Biol Cell. 2010 May 1; 21(9): 1546–1555. doi: 10.1091/mbc.E09-07-0582

PMCID:: PMC2861613

Abstract Article PDF–3.4M

Select item 468365317.

Metabolomic and Gene Expression Profiles Exhibit Modular Genetic and Dietary Structure Linking Metabolic Syndrome Phenotypes in Drosophila

Stephanie Williams, Kelly Dew-Budd, Kristen Davis, Julie Anderson, Ruth Bishop, Kenda Freeman, Dana Davis, Katherine Bray, Lauren Perkins, Joana Hubickey, Laura K. Reed

G3 (Bethesda) 2015 Dec; 5(12): 2817–2829. Published online 2015 Nov 3. doi: 10.1534/g3.115.023564