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1.
Endurance exercise ameliorates phenotypes in Drosophila models of spinocerebellar ataxias
Alyson Sujkowski, Kristin Richardson, Matthew V Prifti, Robert J Wessells, Sokol V Todi
eLife. 2022; 11: e75389. Published online 2022 Feb 16. doi: 10.7554/eLife.75389
PMCID:
PMC8871352
AbstractArticlePDF–5.7M
2.
Sestrin regulates acute chill coma recovery in Drosophila melanogaster
Tyler Cobb, Deena Damschroder, Robert Wessells
Insect Biochem Mol Biol. Author manuscript; available in PMC 2021 Jun 7.
Published in final edited form as: Insect Biochem Mol Biol. 2021 Jun; 133: 103548. Published online 2021 Feb 4. doi: 10.1016/j.ibmb.2021.103548
PMCID:
PMC8180487
AbstractArticlePDF–1.3M
3.
The effects of genetic background on exercise performance in Drosophila
Deena Damschroder, Kristin Richardson, Tyler Cobb, Robert Wessells
Fly (Austin) 2020; 14(1-4): 80–92. Published online 2020 Oct 26. doi: 10.1080/19336934.2020.1835329
PMCID:
PMC7714460
AbstractArticlePDF–3.4M
4.
SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway
Xin Gu, Jose M. Orozco, Robert A. Saxton, Kendall J. Condon, Grace Y. Liu, Patrycja A. Krawczyk, Sonia M. Scaria, J. Wade Harper, Steven P. Gygi, David M. Sabatini
Science. Author manuscript; available in PMC 2018 Nov 10.
Published in final edited form as: Science. 2017 Nov 10; 358(6364): 813–818. doi: 10.1126/science.aao3265
PMCID:
PMC5747364
AbstractArticlePDF–646K
5.
Octopamine Rescues Endurance and Climbing Speed in Drosophila Clkout Mutants with Circadian Rhythm Disruption
Maryam Safdar, Robert J. Wessells
Cells. 2023 Nov; 12(21): 2515. Published online 2023 Oct 25. doi: 10.3390/cells12212515
PMCID:
PMC10648926
AbstractArticlePDF–2.7M
6.
Dietary regulation in health and disease
Qi Wu, Zhi-Jie Gao, Xin Yu, Ping Wang
Signal Transduct Target Ther. 2022; 7: 252. Published online 2022 Jul 23. doi: 10.1038/s41392-022-01104-w
PMCID:
PMC9308782
AbstractArticlePDF–2.6M
7.
Identification of an AMPK Phosphorylation Site in Drosophila TSC2 (gigas) that Regulate Cell Growth
Myungjin Kim, Jun Hee Lee
Int J Mol Sci. 2015 Apr; 16(4): 7015–7026. Published online 2015 Mar 27. doi: 10.3390/ijms16047015
PMCID:
PMC4425001
AbstractArticlePDF–3.1M
8.
Characterizing dopaminergic neuron vulnerability using genome-wide analysis
Jacinta Davis, Claire Da Silva Santos, Narda Caudillo Zavala, Nicholas Gans, Daniel Patracuolla, Monica Fehrenbach, Daniel T Babcock
Genetics. 2021 Aug; 218(4): iyab081. Published online 2021 May 26. doi: 10.1093/genetics/iyab081
PMCID:
PMC8864742
AbstractArticlePDF–1.5M
9.
Exercise and Sestrin Mediate Speed and Lysosomal Activity in Drosophila by Partially Overlapping Mechanisms
Alyson Sujkowski, Robert Wessells
Cells. 2021 Sep; 10(9): 2479. Published online 2021 Sep 19. doi: 10.3390/cells10092479
PMCID:
PMC8466685
AbstractArticlePDF–5.3M
10.
Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila
Xin Gu, Patrick Jouandin, Pranav V. Lalgudi, Rich Binari, Max L. Valenstein, Michael A. Reid, Annamarie E. Allen, Nolan Kamitaki, Jason W. Locasale, Norbert Perrimon, David M. Sabatini
Nature. Author manuscript; available in PMC 2023 Apr 18.
Published in final edited form as: Nature. 2022 Aug; 608(7921): 209–216. Published online 2022 Jul 20. doi: 10.1038/s41586-022-04960-2
Correction in:
Nature. 2022 Sep 13
PMCID:
PMC10112710
AbstractArticlePDF–4.7M
11.
Sestrin2 inhibits mTORC1 through modulation of GATOR complexes
Jeong Sig Kim, Seung-Hyun Ro, Myungjin Kim, Hwan-Woo Park, Ian A. Semple, Haeli Park, Uhn-Soo Cho, Wei Wang, Kun-Liang Guan, Michael Karin, Jun Hee Lee
Sci Rep. 2015; 5: 9502. Published online 2015 Mar 30. doi: 10.1038/srep09502
Correction in:
Sci Rep. 2015; 5: 14029.
PMCID:
PMC4377584
AbstractArticlePDF–2.9M
12.
Sestrins are evolutionarily conserved mediators of exercise benefits
Myungjin Kim, Alyson Sujkowski, Sim Namkoong, Bondong Gu, Tyler Cobb, Boyoung Kim, Allison H. Kowalsky, Chun-Seok Cho, Ian Semple, Seung-Hyun Ro, Carol Davis, Susan V. Brooks, Michael Karin, Robert J. Wessells, Jun Hee Lee
Nat Commun. 2020; 11: 190. Published online 2020 Jan 13. doi: 10.1038/s41467-019-13442-5
PMCID:
PMC6955242
AbstractArticlePDF–2.4M
13.
Disruption of Methionine Metabolism in Drosophila melanogaster Impacts Histone Methylation and Results in Loss of Viability
Mengying Liu, Valerie L. Barnes, Lori A. Pile
G3 (Bethesda) 2016 Jan; 6(1): 121–132. Published online 2015 Nov 6. doi: 10.1534/g3.115.024273
PMCID:
PMC4704710
AbstractArticlePDF–1.5M
14.
Maintenance of metabolic homeostasis by Sestrin 2 and 3
Jun Hee Lee, Andrei V. Budanov, Saswata Talukdar, Eek Joong Park, Hae Li Park, Hwan-Woo Park, Gautam Bandyopadhyay, Ning Li, Mariam Aghajan, Insook Jang, Amber M. Wolfe, Guy A. Perkins, Mark H. Ellisman, Ethan Bier, Miriam Scadeng, Marc Foretz, Benoit Viollet, Jerrold Olefsky, Michael Karin
Cell Metab. Author manuscript; available in PMC 2013 Jun 20.
Published in final edited form as: Cell Metab. 2012 Sep 5; 16(3): 311–321. doi: 10.1016/j.cmet.2012.08.004
PMCID:
PMC3687365
AbstractArticlePDF–5.0M
15.
An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway
Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini
Nat Commun. 2024; 15: 2517. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46680-3
PMCID:
PMC10957897
AbstractArticlePDF–2.0M
16.
The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3
Ambikai Gajan, Valerie L. Barnes, Mengying Liu, Nirmalya Saha, Lori A. Pile
Epigenetics Chromatin. 2016; 9: 4. Published online 2016 Feb 3. doi: 10.1186/s13072-016-0053-9
PMCID:
PMC4740996
AbstractArticlePDF–4.3M
17.
Fat body p53 regulates systemic insulin signaling and autophagy under nutrient stress via Drosophila Upd2 repression
María Clara Ingaramo, Juan Andrés Sánchez, Norbert Perrimon, Andrés Dekanty
Cell Rep. Author manuscript; available in PMC 2022 Apr 25.
Published in final edited form as: Cell Rep. 2020 Oct 27; 33(4): 108321. doi: 10.1016/j.celrep.2020.108321
PMCID:
PMC9036415
AbstractArticlePDF–1.3M
18.
Toxicity of Dithiothreitol (DTT) to Drosophila melanogaster
Yiwen Wang, Maïlys Misto, Jing Yang, Nicole Gehring, Xiaoyu Yu, Bernard Moussian
Toxicol Rep. 2021; 8: 124–130. Published online 2020 Dec 26. doi: 10.1016/j.toxrep.2020.12.014
PMCID:
PMC7782319
AbstractArticlePDF–2.2M
19.
TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich’s Ataxia
Pablo Calap-Quintana, Sirena Soriano, José Vicente Llorens, Ismael Al-Ramahi, Juan Botas, María Dolores Moltó, María José Martínez-Sebastián
PLoS One. 2015; 10(7): e0132376. Published online 2015 Jul 9. doi: 10.1371/journal.pone.0132376
PMCID:
PMC4497667
AbstractArticlePDF–1.1M
20.
Low FoxO expression in Drosophila somatosensory neurons protects dendrite growth under nutrient restriction
Amy R Poe, Yineng Xu, Christine Zhang, Joyce Lei, Kailyn Li, David Labib, Chun Han
eLife. 2020; 9: e53351. Published online 2020 May 19. doi: 10.7554/eLife.53351
PMCID:
PMC7308081
AbstractArticlePDF–11M

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