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Select item 76551071.

The Drosophila Individual Activity Monitoring and Detection System (DIAMonDS)

Ki-Hyeon Seong, Taishi Matsumura, Yuko Shimada-Niwa, Ryusuke Niwa, Siu Kang

eLife. 2020; 9: e58630. Published online 2020 Nov 10. doi: 10.7554/eLife.58630

PMCID:: PMC7655107

Abstract Article PDF–13M

Select item 38898832.

Improved functional abilities of the life-extended Drosophila mutant Methuselah are reversed at old age to below control levels

Agavni Petrosyan, Óscar F. Gonçalves, I-Hui Hsieh, Kourosh Saberi

Age (Dordr) 2014 Feb; 36(1): 213–221. Published online 2013 Aug 3. doi: 10.1007/s11357-013-9568-1

PMCID:: PMC3889883

Abstract Article PDF–453K

Select item 29002003.

The predicted binding site and dynamics of peptide inhibitors to the Methuselah GPCR from Drosophila melanogaster

Jiyoung Heo, William W. Ja, Seymour Benzer, William A. Goddard, III

Biochemistry. Author manuscript; available in PMC 2010 Jul 8.

Published in final edited form as: Biochemistry. 2008 Dec 2; 47(48): 12740–12749. doi: 10.1021/bi801335p

PMCID:: PMC2900200

Abstract Article PDF–2.5M

Select item 28030974.

Extension of Drosophila melanogaster lifespan with a GPCR peptide inhibitor

William W. Ja, Anthony P. West, Jr., Silvia L. Delker, Pamela J. Bjorkman, Seymour Benzer, Richard W. Roberts

Nat Chem Biol. Author manuscript; available in PMC 2010 Jan 7.

Published in final edited form as: Nat Chem Biol. 2007 Jul; 3(7): 415–419. Published online 2007 Jun 3. doi: 10.1038/nchembio.2007.2

PMCID:: PMC2803097

Abstract Article PDF–602K

Select item 22886785.

Functional Significance of Allelic Variation at methuselah, an Aging Gene in Drosophila

Annalise B. Paaby, Paul S. Schmidt

PLoS One. 2008; 3(4): e1987. Published online 2008 Apr 16. doi: 10.1371/journal.pone.0001987

PMCID:: PMC2288678

Abstract Article PDF–333K

Select item 23598566.

An RGS-Containing Sorting Nexin Controls Drosophila Lifespan

Jae Myoung Suh, Drew Stenesen, John M. Peters, Akiko Inoue, Angela Cade, Jonathan M. Graff

PLoS One. 2008; 3(5): e2152. Published online 2008 May 14. doi: 10.1371/journal.pone.0002152

PMCID:: PMC2359856

Abstract Article PDF–524K

Select item 271147.

Adaptive evolution of a candidate gene for aging in Drosophila

Paul S. Schmidt, David D. Duvernell, Walter F. Eanes

Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20): 10861–10865. Published online 2000 Sep 19. doi: 10.1073/pnas.190338897

PMCID:: PMC27114

Abstract Article PDF–100K

Select item 39146848.

Genome-Wide Association Study of Extreme Longevity in Drosophila melanogaster

Molly K. Burke, Elizabeth G. King, Parvin Shahrestani, Michael R. Rose, Anthony D. Long

Genome Biol Evol. 2014 Jan; 6(1): 1–11. Published online 2013 Nov 19. doi: 10.1093/gbe/evt180

PMCID:: PMC3914684

Abstract Article PDF–2.0M

Select item 34440439.

Nutraceutical Interventions for Promoting Healthy Aging in Invertebrate Models

Yuqing Dong, Sujay Guha, Xiaoping Sun, Min Cao, Xiaoxia Wang, Sige Zou

Oxid Med Cell Longev. 2012; 2012: 718491. Published online 2012 Sep 6. doi: 10.1155/2012/718491

PMCID:: PMC3444043

Abstract Article PDF–696K

Select item 1035080210.

Extension of life span by down-regulation of enzymes catalyzing tryptophan conversion into kynurenine: Possible implications for mechanisms of aging

Gregory Oxenkrug, Valeriya Navrotska

Exp Biol Med (Maywood) 2023 Apr; 248(7): 573–577. Published online 2023 Jun 10. doi: 10.1177/15353702231179411

PMCID:: PMC10350802

Abstract Article PDF–799K

Select item 1028952411.

Comparison of toxic effects of 5 macrofungi against Drosophila melanogaster

Jinzhe Li, Yaqin Huang, Dezhi Wang, Nailiang Zhu, Xinrong Qiao

J Insect Sci. 2023 May; 23(3): 20. Published online 2023 Jun 23. doi: 10.1093/jisesa/iead042

PMCID:: PMC10289524

Abstract Article PDF–1.0M

Select item 978576012.

The Role and Mechanism of Polysaccharides in Anti-Aging

Xinlu Guo, Junjie Luo, Jingyi Qi, Xiya Zhao, Peng An, Yongting Luo, Guisheng Wang

Nutrients. 2022 Dec; 14(24): 5330. Published online 2022 Dec 15. doi: 10.3390/nu14245330

PMCID:: PMC9785760

Abstract Article PDF–478K

Select item 573840913.

p53 and cyclin G cooperate in mediating genome stability in somatic cells of Drosophila

Fabienne E. Bayer, Mirjam Zimmermann, Patrick Fischer, Christian Gromoll, Anette Preiss, Anja C. Nagel

Sci Rep. 2017; 7: 17890. Published online 2017 Dec 20. doi: 10.1038/s41598-017-17973-z

PMCID:: PMC5738409

Abstract Article PDF–4.9M

Select item 355203214.

Modulation of Methuselah Expression Targeted to Drosophila Insulin-producing Cells Extends Life and Enhances Oxidative Stress Resistance

Luis E. D. Gimenez, Parakashtha Ghildyal, Kathleen E. Fischer, Hongxiang Hu, William W. Ja, Benjamin A. Eaton, Yimin Wu, Steven N. Austad, Ravi Ranjan

Aging Cell. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Aging Cell. 2013 Feb; 12(1): 121–129. Published online 2012 Dec 6. doi: 10.1111/acel.12027

PMCID:: PMC3552032

Abstract Article PDF–2.6M

Select item 700846215.

Membrane ion channels and receptors in animal lifespan modulation

Yi Sheng, Lanlan Tang, Lijun Kang, Rui Xiao

J Cell Physiol. Author manuscript; available in PMC 2020 Feb 10.

Published in final edited form as: J Cell Physiol. 2017 Nov; 232(11): 2946–2956. Published online 2017 Feb 3. doi: 10.1002/jcp.25824

PMCID:: PMC7008462

Abstract Article PDF–1.1M

Select item 596387116.

Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC

Sigrun Schmähling, Arno Meiler, Yoonjung Lee, Arif Mohammed, Katja Finkl, Katharina Tauscher, Lars Israel, Marc Wirth, Julia Philippou-Massier, Helmut Blum, Bianca Habermann, Axel Imhof, Ji-Joon Song, Jürg Müller

Development. 2018 Apr 1; 145(7): dev163808. Published online 2018 Apr 5. doi: 10.1242/dev.163808